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8篇 您的检索式:作者名="Allan MF"
    题名 作者 年代 出处 被引量
1Acquired segmental colonic hypoganglionosis in an adult Caucasian male:A case report显示文摘BACKGROUND Hypoganglionosis is a rare condition that most often presents with abnormal gastrointestinal transit and usually arises in early childhood or adolescence. Two types have been described(Type I and Type II). The adult-onset form(acquired hypoganglionosis) is extremely uncommon and is thought to arise due to cellular remodelling as a result of chronic inflammation. It differs from Hirschprung's disease in that there is a reduction in ganglion cells in the colonic neural plexuses as opposed to being completely absent.CASE SUMMARY A 31 year-old male presented to hospital with recurrent abdominal pain and vomiting over thirteen months. Abdominal computed tomography scans demonstrated thickening and stranding affecting the transverse, descending and sigmoid colon. Endoscopic appearances were non-specific but confirmed a mixed picture of mucosal inflammation and necrosis in various stages of healing.Numerous investigations were performed to elucidate an underlying aetiology but neither an infective nor ischaemic cause could be proven. Biopsy features were not typical of inflammatory bowel disease. Due to persistence of his symptoms and failure of medical management, a segmental colectomy was performed. Histological examination of the specimen revealed an unexpected finding of segmental hypoganglionosis. Complete surgical excision of the diseased segment of colon was curative and since his operation the patient has had no recurrence of symptoms requiring hospitalisation.CONCLUSION Our case serves to raise awareness of acquired hypoganglionosis as a rare condition that can result from chronic colitis.Allan MF Kwok Andrew B Still Kimberly Hart 2019World Journal of Gastrointestinal Surgery2019,11,2:3
2The M16 mouse: an outbred animal model of early onset polygenic obesity and diabesity显示文摘Allan MF Eisen EJ Pomp D 2004Obes Res2004,12,9:1
3Fatalities due to anaphylactic reactions to foods显示文摘Allan S Anne MF Hugh AS 2001J Allergy Clin Immunol2001,107,1:1
4Further fatalities caused by anaphylactic reactions to food, 2001-2006显示文摘Allan S Anne MF Hugh AS 2007J Allergy Clin Immunol2007,119,4:1
5Further fatalities caused by anaphylactic reactions to food,2001-2006显示文摘Allan S Anne MF Hugh AS 2007J Allergy Clin Immunol2007,119,4:1
6The M16 mouse: an outhred animal model of early onset polygenic obesi- ty and diabesity显示文摘Allan MF Eisen EJPomp D 2004Obes Res2004,12,9:1
7The M16 mouse: an outbred animal model of early onset polygenic obesity and diabesity显示文摘Allan MF Eisen EJ Pomp D 2004Obes Res2004,12,10:1
8Localization ofPeriodl mRNA in the ruminant oocyte and investigations of itsrole in ovarian function显示文摘Cushman RA Allan MF Jones SA 2007Anim Reprod Sci2007,99,12:1
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