3篇
您的检索式：作者名="Alexandre RM"
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| 1 | The Spanish Journal of Psychology 显示文摘 | Alexandre FC Paulo RM | 2008 | 11 (2) :593 -5992008，11，2： | 1 |
| 2 | Nosocomial bloodstream infections in Brazilian hospitals:analysis of 2,563 cases from a prospective nationwide surveillance study显示文摘 | Alexandre RM Luis FC Antonio CP | 2011 | J clin microbiol2011，5，： | 1 |
| 3 | MiRNA in bladder carcinogenesis:A review显示文摘Bladder cancer(BC)is the second urological malignancy in incidence,currently being one of the most neoplasms studied with profile and biology poorly defined.In the world,BC is responsible by about 386000 new cases and 150000 deaths annually with considerable economic impact and high costs for health systems.After its discovery more than 20 years,micro RNAs(miR NAs)have been recognized as molecules that work specifically in post-transcriptional control in majority of eukaryote genomes.MiR NAs are a family of small noncoding RNAs of 19-25 nucleotides in length,expressedin a wide variety of organisms,comprising plants,worms and mammals,including humans.They have a fundamental role in physiological and pathological processes in organs and tissues in a context-dependent manner.This review brings new roles of protective and oncogenic miR NAs linked to carcinogenesis of urothelial carcinoma of the bladder,and associated with behavior of disease.Many studies have demonstrated promising roles of miR NAs working as diagnostic and prognostic biomarkers or involved in target therapies,consolidating mi RNAs as crucial players in human cancer.This review allowed a reflection about the true functions of mi RNAs in bladder carcinogenesis.Not only by their wide capacities of action,but also by abilities in define the cell date.The future of anti-tumor target therapies will be based not in one,but in groups of miR NAs working together in several steps of carcinogenic process,being able to identify the disease,predicting behavior and effectively treat bladder cancer. | Nelson Dip Sabrina T Reis Nayara I Viana Denis R Morais Caio M Moura Betina Katz Daniel K Abe Alexandre Iscaife Iran A Silva Miguel Srougi Kátia RM Leite | 2014 | World Journal of Clinical Urology2014，3，3： | 0 |
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