3篇
您的检索式：作者名="Alexander Mathes"
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| 1 | Hepatoprotective actions of melatonin:Possible mediation by melatonin receptors显示文摘Melatonin,the hormone of darkness and messenger of the photoperiod,is also well known to exhibit strong direct and indirect antioxidant properties. Melatonin has previously been demonstrated to be a powerful organ protective substance in numerous models of injury; these beneficial effects have been attributed to the hormone's intense radical scavenging capacity. The present report reviews the hepatoprotective potential of the pineal hormone in various models of oxidative stress in vivo,and summarizes the extensive literature showing that melatonin may be a suitable experimental substance to reduce liver damage after sepsis,hemorrhagic shock,ischemia/reperfusion,and in numerous models of toxic liver injury. Melatonin's influence on hepatic antioxidant enzymes and other potentially relevant pathways,such as nitric oxide signaling,hepatic cytokine and heat shock protein expression,are evaluated. Based on recent literature demonstrating the functional relevance of melatonin receptor activation for hepatic organ protection,this article finally suggests that melatonin receptors could mediate the hepatoprotective actions of melatonin therapy. | Alexander M Mathes | 2010 | World Journal of Gastroenterology2010，16，48： | 3 |
| 2 | Beneficial effects of hirudotherapy in a chronic case of complex regional pain syndrome显示文摘We report about hirudotherapy in a patient with chronic complex regional pain syndrome(CRPS) in the right hand. CRPS is a multifactorial disease associated with disabling pain as well as sensory and motor deficits. The optimal therapeutic management is based on personalized multimodal treatment approaches;however, hirudotherapy has not been described in the available literature. To date, we have completed five medicinal leech treatments. Altogether, hirudotherapy led to rapid and substantial relief of symptoms, especially with respect to pain intensity ratings and skin temperature asymmetries. In addition, the patient’s active and passive agility of the affected limb improved obviously. | Rebecca Kulbida Alexander Mathes Johannes Loeser | 2019 | Journal of Integrative Medicine2019，17，5： | 2 |
| 3 | Radiation injury显示文摘 | Mathes SJ Alexander J | 1996 | Surg Oncol Clin N Am1996，5，4： | 1 |
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