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| 1 | Association of CagA and VacA presence with ulcer and non-ulcer dyspepsia in a Turkish population显示文摘AIM: The mostly known genotypic virulence features, of H. pyloriare cytotoxin associated gene A (ragA) and Vacuolating cytotoxin gene A (VacA). We investigated the association of these major virulence factors with ulcer and non-ulcer dyspepsia in our region.METHODS: One hundred and forty two dyspeptic patients were studied (average age 44.8±15.9 years, range 15-87years, 64 males and 78 females). Antral and corpus biopsies were taken for detecting and genotyping of H. pylori. 107patients who were H. pylori positive by histological assessment were divided into three groups according to endoscopic findings: Duodenal ulcer (DU), gastric ulcer (GU)and non-ulcer dyspepsia (NUD). The polymerase chain reaction (PCR) was used to detect CagA and VacA genes of H.pylori using specific primers.RESULTS: H.pyloriwas isolated from 75.4 % (107/142) of the patients. Of the 107 patients, 66 (61.7 %) were cagApositive and 82 (76.6 %) were Vacl-positive. CagA gene was positively associated with DU and GU (P<0.01, P<0.02),but not with NUD (P>0.05). Although VacA positivity in ulcer patients was higher than that in NUD group, the difference was not statistically significant (P>0.05).CONCLUSION: There is a significantly positive association between CagA genes and DU and GU. The presence of VacA is not a predictive marker for DU, GU, and NUD in our patients. | Kantarceken Bulent Aladag Murat Atik Esin Koksal Fatih Harputluoglu MMMurat Harputluoglu Hakan Karincaoglu Melih Ares Mehmet Yildirim Bulent Hilmioglu Fatih | 2003 | World Journal of Gastroenterology2003，9，7： | 8 |
| 2 | Melatonin ameliorates cerebral vasospasm after experimental subarachnoidal haemorrhage cot recting imbalance of nitric oxide levels in rats 显示文摘 | Aladag MA Turkoz Y Parlakpinar H | 2009 | Neurochem Res2009，34，11： | 1 |
| 3 | Acute seriousfor primary angioplasty 显示文摘 | Yurtdas M Yaylali YT Aladag N | 2014 | Case Rep Med2014，2014，19： | 1 |
| 4 | 砷暴露工人的主动脉弹性参数评价显示文摘砷对人体健康影响的主要并发症就是高血压。砷相关性高血压,及砷对动脉系统的不良反应如氧化应激、血管收缩/舒张失衡可能导致主动脉的弹性受损。该研究旨在评估砷对主动脉弹性参数,包括主动脉应变力和扩张性的影响。方法:纳入职业性砷暴露工人112例和健康对照组人群60名作为研究对象。 | 刘莉 叶鹏 Karakulak UN Yilmaz OH Tutkun E Aladag E Evranos B Bal C Gunduzoz M Ayturk M Ozturk MT | 2016 | 中华高血压杂志2016，24，4： | 1 |
| 5 | The effect of neighborhood structures on tabu search algorithm in solving course timetabling problem显示文摘 | Aladag C H Hocaoglu G Basaran M A | 2009 | Expert Systems with Applications2009，36，12： | 1 |
| 6 | A new time invariant fuzzy time series forecasting method based on particle swarm optimization显示文摘 | Aladag C H Yolcu U Egrioglu E | 2012 | Original Research Article Applied Soft Computing2012，12，10： | 1 |
| 7 | Seroprevalence of Helicobacter pylori infection in patients with chronic nonspecific pharyngitis: preliminary study显示文摘 | Aladag I Bulut Y Guven M | 2008 | J Laryng01 Otol2008，122，1： | 1 |
| 8 | A new liner&nonlinear artificial neural network model for time series forecasting显示文摘 | Yolcu U Egrioglu E Aladag C H | 2013 | Decision Support System2013，54，3： | 1 |
| 9 | Comparison of five antimicrobial regimens for the treatment of brucellar spondylitis: a prospective, randomized study 显示文摘 | BAY1NDIR Y SONMEZ E ALADAG A | 2003 | J Chemother2003，15，5： | 1 |
| 10 | Effect of trimetazidine on late potentials after acute myocardial infarction显示文摘 | Ozdemir R Tuncer C Aladag M | 1999 | Cardiovasc Drugs Ther1999，13，2： | 1 |
| 11 | The effect of neighborhood structures on tabu search algorithm in sol- ving course timetabling problem 显示文摘 | Aladag C H Hocaoglu G Basaran M A | 2009 | Expert Syst with Ap- pli2009，36，12： | 1 |
| 12 | Forecasting in high order fuzzy times series by using neural networks to define fuzzy relations 显示文摘 | Aladag C H Basaran M A Egrioglu E | 2009 | Expert Systems with Applica- tions2009，36，3： | 1 |
| 13 | A high order fuzzy time series forecasting model based on adaptive expectation and artificial neural networks 显示文摘 | Aladag C H Yolcu U Egrioglu E | 2010 | Mathematics and Computers in Simulation2010，81，4： | 1 |
| 14 | Finding an opti- mal interval length in high order fuzzy time series 显示文摘 | EgTioglu E Aladag C H Yolcu U | 2010 | Ex- pert Systems with Applications2010，37，7： | 1 |
| 15 | The efficacy of Nutrition Risk Screening-2002 (NRS-2002) to decide on the nutritional support in general surgery patients 显示文摘 | Cur AS Ataban K Aladag I | 2009 | Bratislavske Lekarske Listy2009，110，5： | 1 |
| 16 | Erdosteine ameliorates PTZ-in- duced oxidative stress in mice seizure model显示文摘 | Ilhan A Aladag MA Kocer A | 2005 | Brain Res Bulletin2005，65，6： | 1 |
| 17 | Fuzzy time series forecasting method based on Gustafson-Kessel fuzzy cluste- ring显示文摘 | Egrioglu E Aladag C H Yolcu U | 2011 | Expert Systems with Applications2011，38，10： | 1 |
| 18 | The Relationship of Heart Rate Variability with Severity and Prognosis of Cirrhosis显示文摘 | Fehmi Ates Ergun Topal Feridun Kosar Melih Karincaoglu Bulent Yildirim Yuksel Aksoy Murat Aladag Murat M. M. Harputluoglu Ulvi Demirel Hakan Alan Fatih Hilmioglu | 2006 | Digestive Diseases and Sciences2006，，9： | 1 |
| 19 | Forecasting in high order fuzzy time series by using neural networks to define fuzzy relations显示文摘 | Aladag C H Basaran M A Egrioglu E | | 0，，03： | 1 |
| 20 | Erdosteine ameliorates PTZ-induced oxidative stress in mice seizure model显示文摘 | Ilhan A Aladag MA Kocer A | 2005 | Brain ResBull2005，65，6： | 1 |
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