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| 1 | Assessment of knowledge, attitude and practice regarding oxygen therapy at emergency departments in Riyadh in 2017: A cross-sectional study显示文摘BACKGROUND: Administering oxygen therapy(OT) has an essential role in preventing/managing hypoxemia in both acute and chronic conditions. It should be adjusted to achieve the normal oxygen saturation of 94%–98% in most cases. This study aims to evaluate knowledge, attitude and practice(KAP) of nurses, paramedics, emergency medical technicians(EMTs) and Emergency Medical Services(EMS) physicians working at emergency departments(ED) in Riyadh, Saudi Arabia. METHODS: In this cross-sectional study, a structured questionnaire was used to assess KAP related to OT of nurses, paramedics, EMTs and EMS physicians currently working at an ED of a tertiary care hospital. Knowledge and attitude were assessed using a Likert scale from 1–5, whereas practice was assessed as a yes/no categorical variable.RESULTS: A total of 444 emergency health-care workers(EHCWs) participated, of which 225(50.7%) were male, with the majority(77%) in the age group of 20–35 years. Over half of the sample were nurses(266; 59.9%). The mean score for knowledge about OT was 5.51±1.45, attitude was 26.31±3.17 and for practices 4.55±1.76. The main factors which were associated with poor KAP were workload and lack of local guidelines. The distribution of overall practice score was signifi cantly better among paramedics – nurses group and EMT – nurses group.CONCLUSION: This study demonstrates that there is a gap in EHCWs' KAP, particularly regarding when to provide OT to a patient. This gap can affect patients' safety. Extensive educational and training programs about OT are needed to raise awareness among health-care providers. | Amairah Fahad Aloushan Faisal Abdullah Almoaiqel Raid Naysh Alghamdi Fatmah Ismail Alnahari Abdulaziz Fahad Aldosari Nazish Masud Nawfal Abdullah Aljerian | 2019 | World Journal of Emergency Medicine2019，10，2： | 8 |
| 2 | Ordered porous metal oxide semiconductors for gas sensing显示文摘Among various gas sensing materials, metal oxide semiconductors have shown great potential as resistive type sensors. The ordered porous structural metal oxide semiconductors with well-defined meso-or macro-pores chemically synthesized via soft-templating method and nanocasting strategy have high porosity, highly interconnected pore channels and high surface area with enormous active sites for interacting with gaseous molecules. These features enable them good performance in gas sensing,including high sensitivity, fast response and recovery, good selectivity. This review gives a comprehensive summary about the porous metal oxides with focus on the synthesis methods, structure related properties, as well as the modification strategies for gas sensing improved performances. | Xinran Zhou Xiaowei Cheng Yongheng Zhu Ahmed A. Elzatahry Abdulaziz Alghamdi Yonghui Deng Dongyuan Zhao | 2018 | Chinese Chemical Letters2018，29，3： | 5 |
| 3 | Recyclable Fenton-like catalyst based on zeolite Y supported ultrafine,highly-dispersed Fe_2O_3 nanoparticles for removal of organics under mild conditions显示文摘A versatile wet impregnation method was employed to conveniently and controllably deposit Fe_2O_3 nanoparticles on zeolites including commercial Y, mordenite and ZSM-5 with the similar framework Si/Al ratios and crystal sizes, respectively. The ultrafine Fe_2O_3 nanoparticles in size of 5 nm can be highly dispersed on zeolite Y matrix due to its much better wettability than ZSM-5 and mordenite. By using the obtained Fe_2O_3/zeolite composite as the heterogeneous Fenton-like catalysts, the degradation of phenol as a model reaction was systematically investigated, including the zeolite supports, particle size and dispersion of Fe_2O_3, and reaction conditions of H_2O_2 concentration, temperature, and pH value. The catalyst based on zeolite Y with Fe loading of 9% exhibited the best phenol degradation efficiency (> 90%)in neutral pH within 2 h. Its high catalytic activity in Fenton reaction can be attributed to the bifunctional properties of strong surface BrФnsted acidity and high reactivity of octahedral Fe^(3+) in the highlydispersed ultrafine Fe_2O_3 nanoparticles in size of 5 nm, which were the primary active centers to quickly decompose H_2O_2 into hydroxyl radicals. Since phenol degradation can be performed under mild conditions of ambient temperature (283-323 K) and a wide pH range (4.0-7.0), the catalysts can be easily recovered for recyclable use with stable degradation activity, which own the immense potential in deep treatment of organic pollutants in industrial wastewater. | Xuanyu Yang Xiaowei Cheng Ahmed A.Elzatahry Jinyang Chen Abdulaziz Alghamdi Yonghui Deng | 2019 | Chinese Chemical Letters2019，30，2： | 4 |
| 4 | Inflammatory bowel disease: An evaluation of health information on the internet显示文摘AIM To evaluate the quality and accuracy of websites written to the public on inflammatory bowel disease(IBD)(Crohn's disease and ulcerative colitis) and assess their readability level.METHODS Google?, Bing?, and Yahoo? search engines were searched independently by three researchers in December 2014. Only English-language websites were selected on the basis of predetermined inclusion and exclusion criteria. Researchers independently evaluated the quality of each website by using the DISCERN and the HONcode instruments. The readability levels were calculated using two formulas; the Flesch-Kincaid Grade Level Index, and the Coleman-Liau Readability Index. The agreement between the evaluators was calculated using Cohen kappa coefficient.RESULTS Eighty-four websites were finally identified. Scores varied from a minimum DISCERN score of 18 to a maximum of 68 [mean ± SD, 42.2 ± 10.7; median = 41.5, interquartile range, interquartile range (IQR) = 15.8] and a minimum score of HONcode of 0.14 and a maximum of 0.95 (mean ± SD, 0.16 ± 0.19; median = 0.45, IQR = 0.29). Most of these websites were reviewed in 2014 and 2015 (n = 51). The creators of these websites were: universities and research centers(n = 25, 30%), foundations and associations (n = 15, 18%), commercial and pharmaceutical companies(n =25, 30%), charities and volunteer work(n = 9, 10%), and non-university educational bodies (n = 10, 12%). The Flesch-Kincaid Grade Level readability score(mean ± SD) was 11.9 ± 2.4 and the Coleman-Liau Readability Index score was 12.6 ± 1.5. Significant correlation was found between the two readability scores (R2 = 0.509, P = 0.001). The overall agreement between evaluators measured by Cohen kappa coefficient was in the range of 0.804-0.876; rated as 'Good'.CONCLUSION The DISCERN and the HONcode scores of websites varied and the readability levels of most websites were above the public readability level. The study highlights the areas that need further improvement and development in patient education online materials about IBD. | Samy A Azer Thekra I AlOlayan Malak A AlGhamdi Malak A AlSanea | 2017 | World Journal of Gastroenterology2017，23，9： | 4 |
| 5 | Bowel perforation due to break and distal passage of the safety ring of an adjustable intra-gastric balloon: A potentially life threatening situation显示文摘A 45-year-old man of Middle Eastern origin, morbid obese, with a body mass index of 39 had an intragastric balloon, filled with 500 mL of saline/methylene blue and intended as definite therapy, inserted some8 wk previously. He was admitted to the emergency department with abdominal cramps. An ultrasound of the abdomen was performed in ER which confirmed the balloon to be in place without any abnormality.He was discharged home on symptomatic medication.Patient remains symptomatic therefore he reported back to ER 2 d later. Computed tomography scan was performed this time for further evaluation which revealed a metallic ring present in the small bowel while the intra-gastric balloon was in its proper position.There was no clinical or radiological sign of intestinal obstruction. Patient was hospitalized for observation and conservative management. The following night,patient experienced sudden and severe abdominal pain, therefore an X-ray of the abdomen in erect position was done, which showed free air under the right dome of diaphragm. Patient was transferred to O.R for emergency laparotomy. There were two small perforations identified at the site of the metallic ring entrapment. The ring was removed and the perforations were repaired. Due to increasing prevalence of obesity and advances in modalities for its management,physicians should be aware of treatment options, their benefits, complications and clinical presentation of the known complications. Physicians need to be updated to approach these complications within time, to avoid lifethreatening situations caused by these appliances. | Ali M Al-Zubaidi Hassan U Alghamdi Abdu H Alzobydi Irshad A Dhiloon Laeeque A Qureshi | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，4： | 3 |
| 6 | Study on the SEIQR model and applying the epidemiological rates of COVID-19 epidemic spread in Saudi Arabia显示文摘This article attempts to establish a mathematical epidemic model for the outbreak of the new COVID-19 coronavirus.A new consideration for evaluating and controlling the COVID-19 outbreak will be constructed based on the SEIQR Pandemic Model.In this paper,the real data of COVID-19 spread in Saudi Arabia has been used for the mathematical model and dynamic analyses.Including the new reproductive number and detailed stability analysis,the dynamics of the proposed SEIQR model have been applied.The local sensitivity of the reproduction number has been analyzed.The domain of solution and equilibrium based on the SEIQR model have been proved using a Jacobian linearization process.The state of equilibrium and its significance have been proved,and a study of the integrity of the disease-free equilibrium has been carried out.The Lyapunov stability theorem demonstrated the global stability of the current model equilibrium.The SEIQR model has been numerically validated and projected by contrasting the results from the SEIQR model with the actual COVID-19 spread data in Saudi Arabia.The result of this paper shows that the SEIQR model is a model that is effective in analyzing epidemic spread,such as COVID-19.At the end of the study,we have implemented the protocol which helped the Saudi population to stop the spread of COVID-19 rapidly. | Hamdy Youssef Najat Alghamdi Magdy A.Ezzat Alaa A.El-Bary Ahmed M.Shawky | 2021 | Infectious Disease Modelling2021，6，1： | 3 |
| 7 | 喝咖啡和饮茶与分化型甲状腺癌发病风险的前瞻性队列研究显示文摘在细胞和动物研究中,咖啡和茶的成分均显示出一些抗肿瘤活性,包括抗甲状腺癌,但是流行病学证据仍然有限且结果不一致。本研究目的是在大型前瞻性研究中探索咖啡和茶与甲状腺癌的关联。欧洲癌症与营养(EPIC)的前瞻性队列研究共纳入476108名研究对象,采用经各国验证的膳食问卷收集咖啡和茶的摄入情况。在平均14年的随访期间,共发现748例分化型甲状腺癌新发病例,包括601例乳头状癌和109例滤泡状癌。 | 任艳军(编译) Zamora-Ros R Alghamdi MA Cayssials V | 2019 | 中华预防医学杂志2019，53，11： | 2 |
| 8 | Outcomes of Ahmed valve surgery for refractory glaucoma in Dhahran, Saudi Arabia显示文摘AIM: To evaluate the outcomes of Ahmed glaucoma valve(AGV) implantation surgery for refractory glaucoma.METHODS: This one-armed historical cohort study was conducted in 2011. Refractory glaucoma was defined as eyes with an intraocular pressure(IOP) greater than21 mm Hg with maximally tolerated glaucoma medications, failed surgeries, or both. For all eyes with refractory glaucoma that underwent AGV implantation,data were collected on IOP, the best corrected visual acuity(BCVA) and glaucoma medications preoperatively and 4, 6, 12, 24 and 56 wk postoperatively. Logarithm values of IOP were calculated and compared. RESULTS: The study group was comprised of 30patients(30 eyes, 16 males and 14 females) with refractory glaucoma. Mean preoperative IOP was 39.3 ±13.8 mm Hg. Postoperative mean IOP was 15.7±7.1 mm Hg,19.6 ±12.8 mm Hg and 13.9 ±14.2 mm Hg at 12, 24 and56 wk respectively. BCVA was ≥6/60 in 11 eyes preoperatively, and five eyes had BCVA ≥6/60 at 56 wk postoperatively. Preoperatively, more than four medications were used to treat glaucoma in 21 eyes. At12 wk postoperatively, no medications were required to control IOP in 20 eyes. At 56 wk postoperatively, at least one medication was required to control IOP in 10 eyes.Over the entire follow up period, four eyes were treated with yttrium aluminium garnet(YAG) laser and 14 eyes required a second surgery. The AGV was removed in four eyes.CONCLUSION: AGV implantation reduced IOP and the number of medications required to control refractory glaucoma. However, there was a higher risk of decreased vision. Long-term follow up and prompt intervention are recommended. | Tariq Alasbali Abdullah Ali Alghamdi Rajiv Khandekar | 2015 | International Journal of Ophthalmology(English edition)2015，8，3： | 2 |
| 9 | Enhancement of gemcitabine against pancreatic cancer by loading in mesoporous silica vesicles显示文摘Gemcitabine(Gem) is currently the first-line chemotherapeutic drug in management of pancreatic cancer, however the therapeutic efficacy of Gem is limited due to its short half-life and poor cell membrane permeability. Here we designed mesoporous silica vesicles(MSVs) with large pore sizes as a novel drug delivery system. The MSVs were synthesized using cetyltrimethyl ammonium bromide(CTAB) as a structure-directing agent, tetraethoxysilane(TEOS) as silica source in n-hexane/water biliquid system. By virtue of the large pore size and large pore volume of the MSVs, Gem was loaded into the mesoporous of MSVs via 'nanocasting' method. In vitro drug release experiments of gemcitabineloaded MSVs showed an accelerating release of gemcitabine in acidic condition. These fluorescently labeled MSVs could be effectively internalized by both a human(BxPC-3) and a mouse pancreatic cancer cell lines(Pan02). Additionally, some MSVs could even reach the nuclei of the pancreatic cancer cells. Cell viability assays demonstrated that gemcitabine-loaded MSVs exhibited enhanced anticancer activity in inhibiting the proliferation of Bx PC-3 and Pan02 cells compared with free Gem, while the MSVs alone showed no significant cytotoxicity. Our results indicate that our synthesized MSVs might represent a promising novel drug delivery platform for the treatment of pancreatic cancer. | Jun-Tao Dai Yu Zhang Heng-Chao Li Yong-Hui Deng Ahmed A. Elzatahry Abdulaziz Alghamdi De-Liang Fu Yong-Jian Jiang Dong-Yuan Zhao | 2017 | Chinese Chemical Letters2017，28，3： | 2 |
| 10 | Recent advance in synthesis and application of heteroatom zeolites显示文摘Incorporation of heteroatoms into the framewo rk of zeolites has become a significant strategy to improve their performance in catalysis and adsorption,because the obtained heteroatom zeolites exhibit quite different properties from the conventional aluminosilicate zeolites in aspects of surface acidity,pore structures,particle size and so on.In this review,the progress on the heteroatom zeolites including their synthesis and application is highlighted.First,the recent advance on the design and synthesis of different heteroatom zeolites is summarized.Special emphasis is placed on the introduction and comparison of three typical methods,including the direct synthesis,post synthesis and improved direct synthesis,for the traditional heteroatom zeolites(such as TS-1,Sn-MFI,Sn-β) and newly-reported heteroatom zeolites(such as W-MFI,Mo-MFI).According to their intrinsic characteristics,the application of heteroatom zeolites in diverse fields,such as production of fine chemicals,air pollution control and biomass conversion is then discussed.Finally,the challenges and perspective on the future development of heteroatom zeolites in low-cost preparation and practical application are proposed. | Tingting Pang Xuanyu Yang Chenyi Yuan Ahmed A.Elzatahry Abdulaziz Alghamdi Xing He Xiaowei Cheng Yonghui Deng | 2021 | Chinese Chemical Letters2021，32，1： | 2 |
| 11 | 角膜基质环植入术治疗圆锥角膜的临床疗效(英文)显示文摘目的:评估角膜基质环植入术治疗圆锥角膜的临床疗效。方法:这一回顾性对照干预性研究对56例87眼圆锥角膜患者进行手术后随访。所有患者完善眼科检查,评估视力。15眼使用飞秒激光制备角膜隧道。72眼使用机械的方法制备角膜隧道。结果:所有患者术前裸眼视力1.38±0.37。术后4mo裸眼视力达到0.58±0.32。术后16mo达到0.48±0.30。结论:角膜基质环植入术是治疗圆锥角膜的有效方法。有效的干预与理想的术后视力相关。飞秒激光角膜隧道制备和机械方法一样安全。 | Abdullhamid Alghamdi | 2018 | 国际眼科杂志2018，18，8： | 2 |
| 12 | Performance of American Society for Gastrointestinal Endoscopy guidelines for dyspepsia in Saudi population: Prospective observational study显示文摘AIM: To evaluate adherence of primary care physicians(PCPs) to international guidelines when referring patients for upper-gastrointestinal endoscopy(UGE), evaluate the importance of alarm symptoms and the performance of the American Society for Gastrointestinal Endoscopy(ASGE) guidelines in a Saudi population.METHODS: A prospective, observational cross-sectional study on dyspeptic patients undergoing UGE who were referred by PCPs over a 4 mo period. Refer-rals were classified as appropriate or inappropriate according to adherence to ASGE guidelines.RESULTS: Total of 221 dyspeptic patients was enrolled; 161 patients met our inclusion criteria. Mean age was 40.3 years(SD ± 18.1). Females comprised 70.1%. Alarm symptoms included low hemoglobin level(39%), weight loss(18%), vomiting(16%), loss of appetite(16%), difficulty swallowing(3%), and gastrointestinal bleeding(3%). Abnormal endoscopy findings included gastritis(52%), duodenitis(10%), hiatus hernia(7.8%), features suggestive of celiac disease(6.5%), ulcers(3.9%), malignancy(2.6%) and gastroesophageal reflux disease(GERD: 17%). Among patients who underwent UGE, 63% met ASGE guidelines, and 50% had abnormal endoscopic findings. Endoscopy was not indicated in remaining 37% of patients. Among the latter group, endoscopy was normal in 54% of patients. There was no difference in proportion of abnormal endoscopic findings between two groups(P = 0.639).CONCLUSION: Dyspeptic patients had a low prevalence of important endoscopic lesions, and none of the alarm symptoms could significantly predict abnormalendoscopic findings. | Nahla A Azzam Majid A Almadi Hessah Hamad Alamar Lamis Atyah Almalki Rehab Nawaf Alrashedi Rawabi Saleh Alghamdi Waleed Al-hamoudi | 2015 | World Journal of Gastroenterology2015，21，2： | 2 |
| 13 | Hepatic-associated immunoglobulin-A nephropathy in a child with liver cirrhosis and portal hypertension显示文摘 | Alghamdi SA Saadah 0I Almatury N | | 0，，03： | 1 |
| 14 | Osseous grafting part I:autografts and allografts for periodontal regeneration--a literature review显示文摘 | AlGhamdi AS Shibly O Ciancio SG | 2010 | J Int Acad Periodontol2010，12，2： | 1 |
| 15 | Use of plastic adhesive drapes dur- ing surgery for preventing surgical site infections显示文摘 | Webster J Alghamdi AA | 2007 | Cochrane Database Syst Rev2007，4，00： | 1 |
| 16 | Remediation of Cu(Ⅱ), Ni(Ⅱ), and Cr( Ⅲ) ions from simulated wastewater by dendrim- er/titania composites 显示文摘 | BARAKAT M A RAMADAN M H ALGHAMDI MA | 2013 | Journal of Environmental Management2013，117，： | 1 |
| 17 | The pattern of Middle East respiratory syndrome coronavirus in Saudi Arabia:a descriptive epide- miological analysis of data from the Sandi Ministry of Health显示文摘 | Alghamdi IG Hussain II Almalki SS | 2014 | Int J Gen Med2014，7，： | 1 |
| 18 | Use of octreotide for the prevention of pancreatic fistula after elective pancreatic surgery: a systematic review and meta-analysis 显示文摘 | Alghamdi AA Jawas AM Hart RS | 2007 | Can J Surg2007，50，6： | 1 |
| 19 | Microorganisms associated particulate matter:a preliminary study显示文摘 | Alghamdi M A Shamy M Redal M A | 2014 | Sci Total Environ2014，，： | 1 |
| 20 | A square-wave adsorptive stripping voltammetric method for the determination of Amaranth,a food additive dye显示文摘 | Alghamdi AH | 2005 | Journal of AOAC International2005，88，3： | 1 |
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