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| 1 | 我国胆石病十年来的变迁显示文摘作者报道了由全国胆道外科学组组织的来自7个省市、33所医院3911例胆结石手术病例的第二次全国临床调查资料并与十年前首次调查的结果(中华外科杂志1987,25:321~329)比较。调查证实:胆石病仍是我国普外临床的多发病,约占同时期住院患者的11.5%;多见于50岁以上的女性;女:男约2.57:1。约80%的单一部位结石分布于胆囊,以胆固醇类结石为主;而以胆色素类为主的胆管结石仅占10%。与十年前相比,胆囊:胆管结石从1.5:1上升至7.36:1;胆固醇:胆色素结石从1.4:1升至3.4:1。调查还发现:上述关于结石类型及结石部位上的变化与近十年来胆道蛔虫及胆道感染率的显著下降及饮食结构的变化有关。 | Zhu Xueguang Zhang Shengduo HuangZhiqiang et al. People′s Hospital,Beijing Medical U-niversity,Beijing100044. | 1995 | 中华外科杂志1995，33，11： | 155 |
| 2 | 1994年中国糖尿病患病率及其危险因素显示文摘为调查全国糖尿病及糖耐量低减(IGT)的患病率及糖尿病危险因素,对全国19省市年龄≥25岁的224251人群进行横向普查,根据1985年WHO标准,年龄在25~64岁的213515人群中,糖尿病患病率为2.51%,糖耐量低减患病率为3.20%(按1990年全国人口年龄标化后患病率);新诊断糖尿病的比例(70.33%)明显高于已确诊的糖尿病者。现患病率是10年前的3.0倍左右,其中农村患病率的增长高于城市。经多因素logistic逐步回归分析显示,年龄、体重指数或腰臀围比、糖尿病家族史、高血压、低体力活动、高收入为非胰岛素依赖型糖尿病(NIDDM)的独立危险因素,而且在高收入人群中,低文化程度也为NIDDM的独立危险因素。 | Pan Xiaoren *, Yang Wenying, Liu Juan, et al. *Department of Endocrinology, China Japan Friendship Hospital, Beijing 100029 | 1997 | 中华内科杂志1997，36，6： | 415 |
| 3 | Immunohisto chemical Study on the Effects of Pyrethroids on Gluta-mate and γ-Aminobutyric Acid in Rat Central Nervous System显示文摘Objective\ In order to study the effects of pyrethroids on glutamate (Glu) and gamma aminobutyric acid (GABA) in rat central nervous system. Methods\ Male SD rats were treated with permethrin (7 mg/kg, i.p) or cypermethrin (70 mg/kg, i.p) once a day for 3 days. Glu and GABA immunoreactive cells and transmitters in CNS were studied by immunohistochemical method. Results\ The total number, percentage of positive area and integral optical density of glutamate immunoreactive cell in cerebral cortex, hippocampus decreased significantly in permethrin or cypermethrin, while GABA was enhanced. Cypermethrin is more tent than permethrin on either Glu or GABA. Conclusion\ Disturbance of Glu and GABA is likely to play a role in the development of pyrethroids excitatory neurotoxicity. | Wu Jianping, Lu Chun\+1, Wang Ying, et al. Wu Jianping, Lu Chun\+1, Wang Ying, et al. Institute of Toxicology, Nanjing Medical University, Nanjing\ 210029 Acta Universitatis Medicinalis Nanjing,19(6):450 | 1999 | The Journal of Biomedical Research1999，23，2： | 68 |
| 4 | 米索前列醇和PG05配伍米非司酮终止早孕的临床多中心随机比较试验显示文摘本研究为一项由十个单位参加的多中心临床试验,随机比较了三种用药方案:1.米非司酮25mgQ12h×5+PG051mg阴道塞药(组Ⅰ),2.米非司酮,同前十米索600μg(组Ⅱ),3.米非司酮200mg+米索600μg(组Ⅲ)终止早孕的安全性、有效性和可接受性。结果显示完全流产率为94.22%(913/969),其中组Ⅲ为91.50%,明显低于组Ⅰ(95.22%)和组Ⅰ(96.12%)(P=0.025);失败率为1.65%(16/969),其中组Ⅲ为3.52%,显著高于组Ⅰ(1.37%)、组Ⅱ(0%)(P=0.001);不完全流产率为2.89%(28/969),失访(结局不明)率为1.24%(12/969),三组间均无明显差异(P>0.05);自应用PG至孕囊排出时间,三组分别为3.06±1.65,2.81±2.75,3.21±1.61h(X±SD),组Ⅱ稍短于其他两组,其差异有统计学意义(P<0.05);阴道出血持续时间和转经时间无明显组间差异(P>0.05)。90%以上的对象均对药物流产方法表示满意。结果提示米索配伍米非司酮的安全性、有效性和可接受性令人满意;米非司酮低剂量多次给药与米索有较好的协同作用。 | He Chang-hai Gao Er-sheng Chen Jun-hang Gu Jiang Gui You-lnn and Cao Feng-zhen et al.(Collabrating Grou) for Clinical Study on Misoprostol to induce Abortion, Shanghai, 200032) | 1994 | 生殖与避孕1994，14，1： | 47 |
| 5 | 全国第二次冠心病介入性治疗病例注册登记资料分析显示文摘目的 分析 1997年和 1998年我国冠心病介入性治疗发展趋势。方法 采用填写统一发放的表格的方法 ,收集 1997、1998两年各医院冠心病介入性治疗病例资料 ,进行回顾性分析。结果共注册经皮冠状动脉腔内成形术 (PTCA)病例总数 872 5例 ,来自全国范围内 75所医院 ,总成功数 83 69例 (95 9% )。其中 1997年 3 74 0例 ,成功 3 5 5 3例 (95 0 % ) ;1998年 4 985例 ,成功 4 816例 (96 6% )。共扩张病变 10 2 18处 ,成功 965 0处 ,病变成功率为 94 4 %。急性心肌梗死 (AMI)急诊PTCA 10 4 5例 ,成功10 0 1例 (95 8% )。全组患者发生重要并发症 95 9例 (11 0 % ) ,包括死亡 3 2例 (0 3 7% )。冠状动脉支架置入术 63 2 9例 ,共置入支架 774 8只 ,其中左冠状动脉主干置入支架 86只 (占 1 1% )。置入成功7677只 (99 1% )。发生重要并发症 5 10例 (8 1% ) ,包括死亡 2 5例 (0 4 0 % )。全部患者服用噻氯匹啶 ,其中 13 8例 (1 8% )发生粒细胞减少症。另外 ,注册登记冠状动脉斑块旋磨术 93例 (94支血管 ) ,成功率为 93 6%。结论 1997年和 1998年我国冠心病介入治疗例数有大幅度增长 ,两年内完成病例数远远超过过去 12年积累病例总数 ,成功率较过去有增加趋势 ,但地区间及医院间发展仍很不平衡。 | Section of Interventional Cardiology, Chinese Society of Cardiology, Chinese Medical Association, et al. (Correspondent: GAO Runlin. Fu Wai Hospital, PUMC & CAMS, Beijing 100037, China) | 2000 | 中华心血管病杂志2000，28，1： | 50 |
| 6 | An Eperimental Study on the Transplantation of Human Fetal Brain Cells into Monkey Models of Parkinson's Disease.显示文摘Unilateral administration of methly-phenyl-tetrahydropyridine(MPTP) into the common carotid | Liu Zhengou, et al. Dept Neur Ruijin, Hospital. Shanghai Second Med Uni, Shanghai 200025, Chin J Neuro Psych 1994 | 1995 | Chinese Medical Journal1995，，2： | 34 |
| 7 | 64320例烧伤病人的分析显示文摘本文收集和分析了全军1980~1992年29个单位烧伤住院病人64320例,并与前阶段(1958~1979年)分析的16个单位48978例病人进行了对比。本阶段病人伤情虽较前阶段为重,但平均住院日明显缩短,特别有Ⅲ度者缩短达12d之多,总LA50(半数面积死亡率)及有Ⅲ度LA50分别由前阶段的75.93%和46.19%提高到96.99%和90.87%。治疗进步的主要原因,与本阶段广泛采用了早期切痂全覆盖植皮以及休克和感染的防治进步有关。另分析本阶段主要死亡原因为内脏功能不全(50.30%)、全身性感染(19.04%)和吸入性损伤(16.24%),三者占死亡总数的85%以上。为今后防治的重点。内脏功能不全中又以肺功能不全居首位,认为与吸入性损伤关系密切。 | Li Ao Huang Yaosheng Zhang Ning et al.(Third Military Medical College, Chongching 630038) | 1995 | 解放军医学杂志1995，20，1： | 29 |
| 8 | China's wetland change (1990-2000) determined by remote sensing显示文摘Two wetland maps for the entire China have been produced based on Landsat data acquired around 1990 and 2000. Wetlands in China have been divided into 3 broad categories with 15 sub-categories except rice fields. In 1990, the total wetland area in China was 355208 km2 whereas in 2000 it dropped to 304849 km2 with a net loss of 50360 km2. During an approximate 10-year period, inland wetland reduced from 318326 to 257922 km2, coastal wetland dropped from 14335 to 12015 km2, while artificial wetland increased from 22546 to 34911 km2. The greatest natural wetland loss occurred in Heilongjiang, Inner Mon- golia, and Jilin with a total loss of over 57000 km2 of wetland. In western China, over 13000 km2 of wetlands were newly formed in Xinjiang, Tibet, and Qinghai. About 12000 km2 of artificial wetlands were also added for fish farm and reservoir constructions. The newly formed wetlands in western China were caused primarily by climate warming over that region whereas the newly created artificial wetlands were caused by economic developments. China’s wetland loss is caused mainly by human activities. | Peng Gong ZhenGuo Niu Xiao Cheng KuiYi Zhao DeMin Zhou JianHong Guo Lu Liang XiaoFeng Wang DanDan Li HuaBing Huang et al. | 2010 | Science China Earth Sciences2010，53，7： | 28 |
| 9 | 高白细胞性急性白血病 244 例临床分析显示文摘为了解高白细胞性急性白血病(HAL)的临床规律和预后因素。对244例HAL和同期非HAL进行回顾性对照分析。结果显示:发现HAL构成比为8.5%,HAL中急性淋巴细胞白血病(ALL)较多,在急性髓细胞白血病(AML)中M5占的比例最多,为40.5%。HAL发病时肝、脾、淋巴结肿大,DIC,中枢神经系统白血病(CNSL)较非HAL为多。完全缓解(CR)率为41.4%,低于非HAL的54.2%,早期病死率是23.8%。早期死亡的主要原因是颅内出血,占50%。早期死亡的高危因素有发病时Hb≤40g/L,血小板≤30×109/L,DIC,感染,CNSL。结果显示:HAL完全缓解率低,早期死亡率高,预后差,特别是HAL-AML的早期死亡率明显高于HAL-ALL,要重视其早期处理。 | Shanghai Leukemia Cooperation Group Wang Xiaoqin, Lin Guowei, Wang Jun, et al. Shanghai Huashan Hospital, Shanghai 200040 | 1997 | 中华内科杂志1997，36，8： | 27 |
| 10 | Elimination of cholesterol in human endothelial cells显示文摘Eliminationofcholesterolinhumanendothelialcels.XiuRuijuan,DuanChonggao,LiHongwei,etal.InstituteofMicrocirculation,ChineseAcad... | Xiu Ruijuan, Duan Chonggao, Li Hongwei, et al. Institute of Microcirculation, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100005, China. | 1998 | Chinese Medical Journal1998，，1： | 26 |
| 11 | 中日竞走运动员高原训练的生理机能及运动能力的研究显示文摘10名世居高原(2260米)的中国竞走运动员和10名居平原(10m)的日本竞走运动员在多巴(2366米),作4周高原训练。高原训练后期与前期、高原与平原相比,观察到有益的代偿性改变。如运动后的恢复心率(1分至1分10秒)下降加快(13次/分降至105次/分);在负荷心率相近条件下,步速加快(3.61m/s增至3.80m/s),无氧阈速度加快(中方,3.01增至3.22;日方,2.78增至3.30m/s);左室功能有改善(SV:日男由85.4→98.1ml;C1:中男由3.10→3.28L/m^2·min);乳酸—速度曲线右移(日男由7.2→5.4mM,中男由6.2→5.6mM);缓冲系统的能力有改善(女子:BE,—4.7→0.2mM;HCO_3,18.6→25.2mM);肺通气功能有所加强(MVV:中方,108.6→113.5L/min,日方,139.8→146.6L/min)。高原训练后,下平原比赛,中日各有8名队员提高了本人最好成绩。 | Li Hua, et al. (Qinghai Institute of Sports Science, Xining, China 810000)J. Aoki, et al(University of Zuntendo, Japan) Sino-Japanese Research Group for Altitude Training | 1995 | 体育科学1995，15，5： | 23 |
| 12 | Experimental Stody on Immediate Endosseous Implantation.显示文摘Screw type implants (ITI series) were implanted into the socket of extracted teeth of adult dogs to investigate the histologic recovery process of implantation. Two groups | Tan Baosheng, et al. Beijing Hospital of Stomatology, Capital University of Medical Science, Beijing 100050. | 1995 | Chinese Medical Journal1995，，9： | 23 |
| 13 | 空气质量模型及参数选用导则显示文摘本研究是为了在大气污染物浓度估算中提供一个可以接受的技术分析的共同尺度,将所需用的空气质量模式分为三个等级。第一级模式作为在制定大气环境管理的法规和政策时主要应用的模式。第二、三级模式作为研究级模式。本文详细介绍了第一级模式的主要应用原则,简要介绍了第二、三级模式。 | Lin Hong(Chinese Research Academy of Environmental Sciences, Beijing 100012)Sang Jianguo(Beijing University,Beijing 100871)Xu Dahai et al.(The Research Academy of Meteorology, Beijing 100086) | 1993 | 环境科学研究1993，6，4： | 18 |
| 14 | Experimental exploration and research prospect of physical bases and functional characteristics of meridians显示文摘The physical basis of meridians and acupoints (acupuncture points) is in a complex system mainly of connective tissue and interwoven with the blood capillaries, nerves, lymph vessels,etc. Elements of Ca, P, K, Fe, Zn, Mn, etc are found concentrated in the deep connective tissue structures in locations corresponding to acupoints. On this physical basis, the specific waveband of high efficiency for transmission of infrared rays exists in the collagenous fibre in a liquid crystal state. The development direction and new idea of researching on acupuncture and meridians are discussed. | Lun Fei Huansheng Cheng Deheng Cai Shixun Yang Jianrong Xu Eryu Chen Ruishan Dang Guanghong Ding Xueyong Shen Yi Tang et al. | 1998 | Chinese Science Bulletin1998，43，15： | 15 |
| 15 | Progress and records in the study of endogenetic mineralization during collisional orogenesis显示文摘To develop and perfect the theory of plate tectonics and regional metallogeny, metal-logenesis during collisional orogenesis should be thoroughly studied and will attract increasing at-tention of more and more scientists. This paper presents the main aspects of research and discus-sions on metallogenesis during collisional orogenesis after the development of plate tectonics, and accordingly divides the study history into two stages, i.e. the junior stage during 1971-1990 and the senior stage after 1990. Beginning with the negation of mineralization in the collision regime by Guild (1971), the focus of study was put on whether there occurred any mineralization during collisional orogenesis at the junior stage. At the senior stage, which is initiated by the advance of met-allogenic and petrogenic model for collisional orogenesis, scientists begin to pay their attention to the geodynamic mechanism of metallogenesis, spatial and temporal distribution of ore deposits, ore-forming fluidization, relationship | Yanjing Chen Huayong Chen Yulin Liu Guangjun Guo Yong Lai Shan Qin Baoling Huang Zengjie Zheng Yinghui Sui Chao Li et al. | 2000 | Chinese Science Bulletin2000，45，1： | 13 |
| 16 | Isolation and Identification of a Specific cDNA Mapping to the Bam HI-I2 and -LFragments within the Inverted Repeats ofUnique Long Re-gion (IRL) in the Genom e ofMarek′s Disease Herpesvirus (MDV) Oncogenic Strain Beijing-1显示文摘Objective\ To understand the transcription of BamHI L DNA fragment from genome of strong virulent GA strain of Marek′s disease herpesvirus (MDV) in lymphoblastoid tumor tissue induced by oncogenic strain Beijing 1 (a specific local strain in China) of MDV. Methods\ Two oligonucleotide primers were synthesized according to the reported sequence of \%meq\% gene an ideal oncogenic candidate and our previously determined sequence of BamHI L fragment of Marek′s disease herpesvirus (MDV), respectively. Reverse transcriptase PCR(RT PCR) assay was performed by using these primers and the mRNA as a template which was isolated from visceral lymphoblastoid tumors obtained from chickens artificially infected with strain Beijing 1 of oncogenic MDV. Southern blot molecular hybridization was further carried out to detect the product of RT PCR with digoxigenin labeled nucleotide probe from BamHI I2 and L fragment in the gene library of MDV strain GA, respectively. Results\ Two probes could simultaneously hybridize this cDNA amplified by RT PCR with a length of about 730 bp. Conclusion\ It is suggested that \%meq\% transcription could extend from the right hand end of BamHI I2 to the adjacent BamHI L, and the BamHI L region was likely to be transcribed in MDV induced lymphoblastoid tumors. | Lu Chun, Wu Jianping, Zhang Xunhai, et al. Lu Chun, Wu Jianping, Zhang Xunhai, et al. Department of Microbiology and Immunology, Nanjing Medical University, Nanjing\ 210029 Acta Universitatis Medicinalis Nanjing, 19(6):447 | 1999 | The Journal of Biomedical Research1999，23，2： | 13 |
| 17 | 南方阔叶树材干燥初期应变特点的研究显示文摘在不同温度和平衡含水率条件下研究南方阔叶树材干燥初期应变特点。试验结果表明,干燥初期表层呈现伸张弹性应变和塑性应变,内层为压缩应变,伸张弹性应变的最大值是产生表裂的主要原因,塑性应变而引起的表层固定变形是产生内裂的原因。弹性和塑性应变受平衡含水率的影响较大,并且与含水率梯度存在相关关系、干燥初期阶段的延续时间,可由表层达到最大伸张应变时的含水率与初含水率的比值来确定。 | Guo Yanming et al. (Research Institute of Wood Industry,CAF,Beijing 100091) | 1995 | 木材工业1995，9，4： | 13 |
| 18 | 我国不同地区稻田甲烷排放量及控制措施研究显示文摘1993—1995连续3年在天津模拟微型小区进行了4组水稻对比试验,1995年又在武汉和广州大田上进行了两组早晚稻验证试验,研究不同地区稻田甲烷排放通量及其控制措施,包括:施用沼渣代替普通堆肥(A),施用包被复合肥(B)、硫铵(C)、硝铵(D)代替尿素,稻田间歇落干(E),以及施用氧化硅粉(F)等农作措施,对减少稻田甲烷排放量的作用。每种设计措施重复2—3年。试验结果表明:①不施或轻施堆肥(主要施用化肥)的稻田甲烷排放通量中值范围为0.66—13.39(天津一季稻0.66—1.70,南方早稻5.67,晚稻13.39)mg/(m2·h),可代表我国稻田一般情况。特别重施堆肥的稻田甲烷排放量中值范围分别为18.80—28.48mg/(m2·h)(包括晚稻),与国外报告的平均范围相当;但重施腐熟沼渣的与单施尿素的甲烷排放通量无差异。②6项设计控制甲烷的措施比同等无控制措施农作方法减少稻田甲烷排放量11%—90%以上,水稻产量无显著增减。综合归纳各种设计措施减少稻田甲烷排放通量中值依次排列为:A(97.9%)>B(44.0%)>F(43.5%)>C,D(41.1%)>E(33.6%)。 | Tao Zhan et al.(Agro-environ.Prot.Inst., Tianjin, 300191) , | 1998 | 农业环境保护1998，17，1： | 12 |
| 19 | Study on Lymphokine-Activated Killer Cells Induced from Cord Blood显示文摘 | Wang Yi-feng, et al. Affiliated Hospital, Shandong Med Uni, Jinan 250012. Chin J Obst Gynecol 1994 | 1994 | Chinese Medical Journal1994，，8： | 12 |
| 20 | 新型固定式宫内节育器与TCu220C的临床效果比较性研究显示文摘本文系研究新型固定式宫内节育器(Fix—CuU300IUD)的临床避孕效果、副反应和可接受性,选用目前公认较为理想的TCu220C作对照,采用多中心随机比较性研究。自1993年2月至5月共接收合格对象2104例(各1052例),1年随访率为99.95%。使用12个月结果表明:FIX-Cu300IUD累积妊娠率为0.09%,对照组为1.43%(P<0.01);脱落率分别为0.95%和2.28%(P<0.05);因症取出率依次为1.04%和2.09%(P>0.05);续用率分别为97.33%和93.82%(P<0.05)。98%以上受试者对所使用的Fix-Cu300IUD的避孕效果满意,证实此种IUD符合WHO的可接受性IUD标准。 | Wang Shuzhen,et al. Wu Han New Type Fix - Cu IUD ResearchGroup, 430030. | 1995 | 中国实用妇科与产科杂志1995，11，4： | 11 |
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