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1篇 您的检索式:作者名="Akpan Joseph Linus"
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1Antimalarial potency of the leaf extract of Aspilia africana(Pers.) C.D.Adams显示文摘Objective:To investigate the antimalarial activity of ethanol extract of Aspilin africana (A.africana) leaf.Methods:The ethanol extract of A.africana leaf(100-400 mg/kg) was screened for blood schizonticidal effect against chloroquine-sensitive Plasmodium berghei(P. berghei) in mice both in early and established models of antimalarial studies.Results:The leaf extract exhibited significant(P<0.05) antiplasmodial activity in 4-day early infection and in established infection tests with a considerable mean survival time comparable to that of standard drug,chloroquine(10 mg/kg).Conclusions:The findings show thai ethanol extract of A.africana leaf possesses potent antiplasmodial activity which justify the use in ethnomedicine and can be developed in malaria therapy.Akuodor Godwin Christian Amos Grace Mfon Essien Augustine Dick Essien David-Oku Akpan Joseph Linus Ezeokpo Basil Chukwuma 2012Asian Pacific Journal of Tropical Medicine2012,5,2:2
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