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| 1 | A predictive score for retinopathy of prematurity by using clinical risk factors and serum insulin-like growth factor-1 levels显示文摘AIM: To detect the impact of insulin-like growth factor-1(IGF-1) and other risk factors for the early prediction of retinopathy of prematurity(ROP) and to establish a scoring system for ROP prediction by using clinical criteria and serum IGF-1 levels.METHODS: The study was conducted with 127 preterm infants. IGF-1 levels in the 1 st day of life, 1 st, 2 nd, 3 rd and 4 th week of life was analyzed. The score was established after logistic regression analysis, considering the impact of each variable on the occurrences of any stage ROP. A validation cohort containing 107 preterm infants was included in the study and the predictive ability of ROP score was calculated.RESULTS: Birth weights(BW), gestational weeks(GW) and the prevalence of breast milk consumption were lower, respiratory distress syndrome(RDS), bronchopulmonarydysplasia(BPD) and necrotizing enterocolitis(NEC) were more frequent, the duration of mechanical ventilation and oxygen supplementation was longer in patients with ROP(P<0.05). Initial serum IGF-1 levels tended to be lower in newborns who developed ROP. Logistic regression analysis revealed that low BW(<1250 g), presence of intraventricular hemorrhage(IVH) and formula feeding increased the risk of ROP. Afterwards, the scoring system was validated on 107 infants. The negative predictive values of a score less than 4 were 84.3%, 74.7% and 79.8% while positive predictive values were 76.3%, 65.5% and 71.6% respectively.CONCLUSION: In addition to BW <1250 g and IVH, formula consumption was detected as a risk factor for the development of ROP. Breastfeeding is important for prevention of ROP in preterm infants. | Yesim Coskun Ceyhun Dalkan Ozge Yabas Ozlem Onay Demirel Elif Samiye Bayar Sibel Sakarya Tuba Muftuoglu Dilaver Ersanli Nerin Bahceciler ipek Akman | 2017 | International Journal of Ophthalmology(English edition)2017，10，11： | 4 |
| 2 | Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats显示文摘Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle cerebral artery occlusion were intraperitoneally administered daidzein. Biochemical and immunohistochemical tests showed that superoxide dismutase and nuclear respiratory factor 1 expression levels in the brain tissue decreased after ischemia and they increased obviously after daidzein administration; malondialdehyde level and apoptosis-related cysteine peptidase caspase-3 and caspase-9 immunoreactivity in the brain tissue increased after ischemia and they decreased obviously after daidzein administration. Hematoxylin-eosin staining and luxol fast blue staining results showed that intraperitoneal administration of daidzein markedly alleviated neuronal damage in the ischemic brain tissue. These findings suggest that daidzein exhibits neuroprotective effects on ischemic brain tissue by decreasing oxygen free radical production, which validates the aforementioned hypothesis. | Adem Bozkurt Aras Mustafa Guven Tar?k Akman Adile Ozkan Halil Murat Sen Ugur Duz Y?ld?ray Kalkan Coskun Silan Murat Cosar | 2015 | Neural Regeneration Research2015，10，1： | 4 |
| 3 | Imatinib response of gastrointestinal stromal tumor patients with germline mutation on KIT exon 13:A family report显示文摘Familial gastrointestinal stromal tumor(GIST) is a rare autosomal dominant disorder associated with mutations in the KIT gene in the majority of cases. Although, exon 11 appears to be the hot spot region for approximately 95% of germline mutations, pathogenic variations have also been identified in exon 8, 13 and 17. Exon 13 germline mutations are extremely rare amongst familial GISTs and seven families with a germline mutation have been reported to date. Moreover, the role of imatinib mesylate in this rare familiar settings is not completely known so far. We describe here clinical, imaging, pathological and genetic findings of a family with four affected members; grandmother, his son and two grand-sons having a germline gain-of-function mutation of KIT in exon 13 and discuss the imatinib mesylate treatment surveillance outcomes towards disease management. | Gulgun Engin Serpil Eraslan Hülya Kayserili Yersu Kapran Haluk Akman Ali Akyuz Nuri Faruk Aykan | 2017 | World Journal of Radiology2017，9，9： | 3 |
| 4 | Open reduction of a total talar dislocation: A case report and review of the literature显示文摘BACKGROUND Total talar dislocation (TTD) is very uncommon for many orthopedic surgeons and emergency/trauma specialists. Scarce cases of TTD have been reported, mainly in the form of open fracture-dislocation injury. CASE SUMMARY We report a very rare injury of closed TTD with a follow-up period of 36 mo. Initial closed reduction was not successful because of a fractured highly unstable medial malleolus displaced into the ankle mortise, blocking the relocation of the talus. The patient was able to walk pain-free after the 3rd month of surgery. At the 36-mo follow-up, there were 10 degrees of flexion loss and 10 degrees of extension loss in the tibiotalar joint. Furthermore, 5 degrees of subtalar joint inversion-eversion loss was present. CONCLUSION Open reduction should be performed for closed TTDs unless closed reduction is successful. | Furkan Yapici Mehmet Coskun Muhammet Coskun Arslan Erman Ulu Yunus Emre Akman | 2019 | World Journal of Clinical Cases2019，7，14： | 2 |
| 5 | Syringaldehyde exerts neuroprotective effect on cerebral ischemia injury in rats through anti-oxidative and anti-apoptotic properties显示文摘There are few studies on the neuroprotective effects of syringaldehyde in a rat model of cerebral ischemia. The study aimed to elucidate the mechanisms underlying the neuroprotective effects of syringaldehyde on ischemic brain cells. Rat models of cerebral ischemia were intraperitoneally administered syringaldehyde. At 6 and 24 hours after syringaldehyde administration, cell damage in the brain of cerebral ischemia rats was obviously reduced, superoxide dismutase activity and nuclear respiratory factor 1 expression in the brain tissue were markedly increased, malondiadehyde level was obviously decreased, apoptosis-related cysteine peptidase caspase-3 and-9 immunoreactivity was obviously decreased, and neurological function was markedly improved. These findings suggest that syringaldehyde exerts neuroprotective effects on cerebral ischemia injury through anti-oxidation and anti-apoptosis. | Aras Adem Bozkurt Guven Mustafa Akman Tar?k Ozkan Adile Sen Halil Murat K?l?coglu Mesut Kalkan Y?ld?ray Silan Coskun Cosar Murat | 2014 | Neural Regeneration Research2014，9，21： | 2 |
| 6 | Visa trial of international trade:evidence from support vector machines and neural networks显示文摘International trade depends on networking,interaction and in-person meetings which stimulate cross-border travels.The countries are seeking policies to encourage inbound mobility to support bilateral trade,tourism,and foreign direct investments.Some nations have been implementing liberal visa regimes as an important part of facilitating policies in view of security concerns.Turkey has been among the nations introducing liberal visa policies to support trade in the last decade and recorded significant increases in the volumes of exports.In this paper,we employed machine learning methodologies,Support vector machines(SVM)and Neural networks(NN),to investigate the facilitating impact of liberal visa policies on bilateral trade,using the export data from Turkey for the period of 2000–2014.The research disentangled the variables that have the strongest impact on trade utilizing SVM and NN models and exhibited that visa policies have significant impacts on the bilateral trade.More relaxed visa policies are recommended for the countries in the pursuit of increasing exports. | Engin Akman Abdullah S.Karaman Cemil Kuzey | 2020 | Journal of Management Analytics2020，7，2： | 2 |
| 7 | Isokinetic measurement of trunk muscle strngth in woman with chronic low-back pain显示文摘 | Bayramoglu M Akman MN Kilinic S | 2001 | Am J Phys Med Rehabil2001，80，9： | 1 |
| 8 | Magnetic resonance imaging of tuberculous spondylitis 显示文摘 | Akman S Sirvanci M Talu U | 2003 | Orthopedics2003，26，1： | 1 |
| 9 | Comparison of percutaneous nephrolithotomy and retrograde flexible nephrolithotripsy for the management of 2-4 cm stones: a matched-pair analysis 显示文摘 | Akman T Binbay M Ozgor F | 2012 | BJU int2012，109，9： | 1 |
| 10 | Nonconvulsive status epilepticus and continuous spike and slow wave of sleep in children显示文摘 | Akman CI | 2010 | Seminars in Pediat Neurol2010，17，3： | 1 |
| 11 | Factors affecting bleeding during percutaneous nephrolithotomy:single surgen experience显示文摘 | AKMAN T BINBAY M SARI E | 2011 | J Endourol2011，25，2： | 1 |
| 12 | Current Approaches to Punctuation in Computational Linguistics显示文摘 | Say B Akman V | 1997 | Computers and the Humanities1997，30，6： | 1 |
| 13 | Auditory neuropathy in hyperbilirubinemia: ls there a correlation between serum bilirubin, neuron-specific enolase levels and audilory neuropathy显示文摘 | Akman I Ozek E Kulekei S | 2004 | Inl J Audiol2004，43，9： | 1 |
| 14 | Congenital vulvar lymphangioma circumscriptum显示文摘 | Dikmen Y Terek MC Akman L | 2008 | Int J Clin Oncol2008，13，5： | 1 |
| 15 | Auditory neuropathy in hyperbilirubinemia :Is there a correlation between serum bilirubin, neuron -specific enolase levels and auditory neuropathy显示文摘 | Akman I Ozek E Kulekci S | 2004 | Int J Audiol2004，43，9： | 1 |
| 16 | Penile anatomy under the pubic arch: reconstructive implications显示文摘 | Akman Y Liu W Li YW | 2001 | J Urol2001，166，1： | 1 |
| 17 | A comparison of the postoperative analgesic efficacy of single-dose epidural tramadol versus morphine in children显示文摘 | Demiraran Y Kocaman B Akman RY | 2005 | Br J Anaesth2005，95，4： | 1 |
| 18 | Nonconvulsive status epilepticus and continuous spike and slow wave of sleep in children 显示文摘 | Akman CI | 2010 | Semin Pediatr Neuro12010，17，5： | 1 |
| 19 | Tubeless procedure is most important factor in reducing length of hospitalization after per- cutaneous nephrolithotomy:results of univariable and multivariable models 显示文摘 | AKMAN T BINBAY M YURUK E | 2011 | Urology2011，77，2： | 1 |
| 20 | Treatment of acne with intermittent and conventional isotretinoin:a randomized,controlled multicenter study显示文摘 | Akman A Durusoy C Senturk M | | 0，，10： | 1 |
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