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| 1 | Efficacy of mosapride citrate with polyethylene glycol solution for colonoscopy preparation显示文摘AIM:To evaluate the efficacy and safety of adjunctive mosapride citrate for bowel preparation before colonoscopy. METHODS:We conducted a randomized,double-blind, placebo-controlled study with mosapride in addition to polyethylene glycol(PEG)-electrolyte solution.Of 250 patients undergoing colonoscopy,124 were randomized to receive 2 L PEG plus 15 mg of mosapride citrate (mosapride group),and 126 received 2 L PEG plus placebo(placebo group).Patients completed a questionnaire reporting the acceptability and tolerability of the bowel preparation process.The efficacy of bowel preparation was assessed by colonoscopists using a 5-point scale based on Aronchick's criteria.The primary end point was optimal bowel preparation rates(scores of excellent/good/fair vs poor/inadequate). RESULTS:A total of 249 patients were included in the analysis.In the mosapride group,optimal bowel preparation rates were significantly higher in the left colon compared with the placebo group(78.2%vs 65.6%,P<0.05),but not in the right colon(76.5%vs 66.4%,P=0.08).After excluding patients with severe constipation,there was a significant difference in bowel preparation in both the left and right colon(82.4%vs 66.7%,80.8%vs 67.5%,P<0.05,P<0.01).The incidence of adverse events was similar in both groups. Among the subgroup who had previous colonoscopy experience,a significantly higher number of patients in the mosapride group felt that the current preparation was easier compared with patients in the placebo group(34/72 patients vs 24/74 patients,P<0.05). CONCLUSION:Mosapride citrate may be an effective and safe adjunct to PEG-electrolyte solution that leads to improved quality of bowel preparation,especially in patients without severe constipation. | Masahiro Tajika Yasumasa Niwa Vikram Bhatia Hiroki Kawai Shinya Kondo Akira Sawaki Nobumasa Mizuno Kazuo Hara Susumu Hijioka Kazuya Matsumoto Yuji Kobayashi Akira Saeki Asana Akabane Koji Komori Kenji Yamao | 2012 | World Journal of Gastroenterology2012，18，20： | 21 |
| 2 | Successful surgical resection of ruptured cholangiolocellular carcinoma:A rare case of a primary hepatic tumor显示文摘Spontaneous rupture is one of the most fatal complications of hepatic tumors such as hepatocellular carcinoma. In fact, many studies have shown that the in-hospital and 30-d mortality rates are as high as 25%-100%. Cholangiolocellular carcinoma(Co CC) is a rare primary hepatic tumor, usually small in size, that is thought to originate from the ductules and/or canals of Hering. Here, we present a case of spontaneous rupture of a Co CC that was successfully resected by radical surgery. Although Co CC is a rare primary hepatic tumor, it demonstrates certain specific clinical features, including a better prognosis than for other primary liver cancers, and thus should be distinguished from those other cancers. Moreover, Co CC can appear as a ruptured huge tumor, and when it does, radical hepatectomy can be an effective measure to achieve both absolute hemostasis and curability of tumor. | Shota Akabane Takushiro Ban Shunsaku Kouriki Hiroyuki Tanemura Haruhiro Nakazaki Masayuki Nakano Nobuaki Shinozaki | 2017 | World Journal of Hepatology2017，9，16： | 2 |
| 3 | Surgicaloutcomes in juvenile retinal detachment 显示文摘 | Akabane N Yamamoto S Tsukahara I | 2001 | Jpn Jophthalmol2001，45，4： | 1 |
| 4 | Monitoring visual evoked potentials during retraction of the canine optic nerve:protective effect of unroofing the optic canal显示文摘 | AKABANE A SAITO K SUZUKI Y | 1995 | J Neurosurg1995，82，： | 1 |
| 5 | Computed tomography fol- low-up for the detection of hepatocellular carcinoma recurrence after initial radiofrequency ablation: a single-center experience 显示文摘 | Mikami S Tateishi R Akabane M | 2012 | J Vasc Interv Radiol2012，23，10： | 1 |
| 6 | Esti- mating stature from the length of the lumbar part of the spine in Japanese显示文摘 | Terazawa K Akabane H Gotouda H | 1990 | Med Sci Law1990，30，4： | 1 |
| 7 | Retinal ischemia and angle neovasculafization in proliferate diabetic retinopachy显示文摘 | Hamanaka T Akabane N Yajina J | 2001 | Am J Ophthalmol2001，132，4： | 1 |
| 8 | Induction of brain-derived neuretrophic factor(BDNF) and the receptor trk B mRNA following middle cerebral artery occlusion in Rat 显示文摘 | Arai S Kinouchi H Akabane A | 1996 | Neuorsci Lett1996，211，1： | 1 |
| 9 | Identification of a novel male germ cell-specific gene TESF-l in mice显示文摘 | Fan J Graham M Akabane H | 2006 | Biochem Biophys Res Commun2006，340，1： | 1 |
| 10 | Expression of prostaglandin F2alpha(PGF2alpha)receptor and its isoforms in the bovine corpus luteum during the estrous cycle and PGF2alpha-induced luteolysis显示文摘 | Shirasuna K Akabane Y Beindorff N | 2012 | Domest Anim Endocrinol2012，43，3： | 1 |
| 11 | Monitoring visual evoked potentials during retrction of the canine optic nerve,Protective effect of unroofing the optic canal显示文摘 | Akabane A Saito K Suzuki Y | 1995 | J Neurosurg1995，82，3： | 1 |
| 12 | Retinal ischemia and angle neovasculafization in proliferative diabetic retinopathy显示文摘 | Hamanaka T Akabane N Yajina T | | 0，，04： | 1 |
| 13 | Induction of brain derived neurotrophic fator and the receptor rukB mRNA following middle cerebral artery occlusion in rat显示文摘 | Arai S Kinouchi H Akabane A | 1996 | Neurosci Lett1996，211，1： | 1 |
| 14 | Vitrectomy for diabetic macular edema:the role of posterior vitreous detachment and epimacular mem- brane 显示文摘 | Yamamoto T Akabane N Takeuchi S | 2014 | Ophthalmol2014，132，： | 1 |
| 15 | Surgical outcomes in juvenile retinal detachment显示文摘 | Akabane N Yamamoto S Tsukahara I Ishida M Mitamura Y Yamamoto T | 2001 | Jpn J Ophthalmol2001，45，4： | 1 |
| 16 | Monitoring visual evoked potentials during retraction of the canine optic nerve:protetive effect of unroofing the optic canal显示文摘 | Akabane A Saito K Suzuki Y Shibuya M Sugita K | 1995 | J Neuro Surg1995，82，： | 1 |
| 17 | Production and characterization of antibodies reactive with leukotoxin 显示文摘 | Akabane H Nagao M Zhang W-D | 1993 | Jpn J Leg Med1993，47，： | 1 |
| 18 | Induction of brain-derived neurotrophic factor(BDNF) and the recepter trkB mRNA filowing middle cerebral artery occlusion in rat显示文摘 | Arai S Kinouchi H Akabane A | 1996 | Neurosci Lett1996，211，1： | 1 |
| 19 | Effect of MX-68 on air- way inflammation and hyperresponsiveness in mice and guinea- pigs 显示文摘 | Nagao K Akabane H Masuda T | 2004 | J Pharm Pharmacol2004，56，2： | 1 |
| 20 | Immunoreactive endothelin-1 contents in brain regions from spontaneously hypertensive rats显示文摘 | Kawano Y Akabane S | 1991 | J Cardiovasc Pharmacol1991，17，7： | 1 |
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