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| 1 | Serum vitamin D content is associated with semen|parameters and serum testosterone levels in men显示文摘The present study aimed to evaluate the influence of serum vitamin D levels on semen quality and testosterone levels.This is a crosssectional study conducted at Androscience,Science and Innovation Center in Andrology and High-Complex Clinical and Andrology Laboratory in Sao Paulo,Brazil,with 508 male patients,aged 18-60 years,from 2007 to 2017.Seminal parameters and serum sexual hormones were correlated with serum vitamin D concentrations in 260 men selected by strict selection criteria.Patients were divided into normozoospermic group(NZG,n=124)and a group with seminal abnormalities(SAG,n=136).Evaluation included complete physical examination,past medical history,habits and lifestyle factors,two complete seminal analysis with sperm functional tests,serum levels of 25-hydroxy-vitamin D_(3)(25(OH)VD_(3)),total and free testosterone,luteinizing hormone(LH),follicle-stimulating hormone(FSH),sex hormone-binding globulin(SHBG),total cholesterol,homeostatic model assessment of insulin resistance(HOMA-IR)index,and karyotype.The mean concentration of 25(OH)VD_(3)was significantly lower in the SAG(P<0.001)and positively correlated with all baseline seminal parameters and total testosterone levels.In addition,serum vitamin D_(3)concentration was found to be positively correlated with sperm concentration(β=2.103;P<0.001),total number of spermatozoa with progressive motility(β=2.069;P=0.003),total number of motile spermatozoa(β=2.571;P=0.015),and strict morphology(β=0.056;P=0.006),regardless of other variables.This is the first comparative study to address the issue of serum vitamin D_(3)content between normozoospermic patients and those with sperm abnormalities.It clearly demonstrates a direct and positive relationship between serum vitamin D level and overall semen quality,male reproductive potential,and testosterone levels. | Inari M Ciccone Elaine MF Costa Juliana R Pariz Thiago A Teixeira Joel R Drevet Parviz Gharagozloo Robert J Aitken Jorge Hallak | 2021 | Asian Journal of Andrology2021，23，1： | 2 |
| 2 | Dimeric inhibins in amniotic fluid, maternal serum, and fetal serum in human pregnancy显示文摘 | Riley SC Crossley JA Ritoe SC Horne A Shade M Ellis PM Aitken DA Groome NP | 1997 | J Clin Endocrinol Metab1997，82，1： | 1 |
| 3 | Redox regulation of tyro- sine phosphorylation in human spermatozoa and its role in human spermatozoa and its role in human sperm function 显示文摘 | Aitken R J Paterson M Fisher H | 1995 | J Cell Sci1995，108，： | 1 |
| 4 | A cDNA encoding farnesyl pyrophosphate synthase in white lupin 显示文摘 | Attucci S Aitken S M Ibrahim R K | 1995 | Plant Physiol1995，108，： | 1 |
| 5 | Prescription drug spending trends in the United States: looking beyond the turning point 显示文摘 | AITKEN M BERNDT ER CUTLER DM | 2009 | Health Aft (Millwood)2009，28，1： | 1 |
| 6 | Swithing maternal dietary intake at the end of the first trimester has profound effects on placenta development and fetal growth in adolescent ewes carrying singleton fetuses显示文摘 | WALLACE J M BOURKE M D A AITKEN R P | 1999 | Biol Reprod1999，61，： | 1 |
| 7 | Prevalence of clinical sinusitis in young chil- dren followed up by primary care pediatricians显示文摘 | Aitken M Taylor JA | 1998 | Arch Pediatr Adolesc Med1998，152，： | 1 |
| 8 | Prescription Drug Spending Trends in the United States: Looking Beyond the Turning Point显示文摘 | Aitken M Berndt ER Cutler DM | 2009 | Health Affair (Millwood)2009，28，1： | 1 |
| 9 | Oxidation of phenolic pollutants by a lignin degrading enzyme from the white-rotfungus Phanerochaete chrysosporium显示文摘 | AITKEN M D VENKATADRI R IRVINE R L | 1989 | Water Research1989，23，4： | 1 |
| 10 | Surfactant enhanced dissolution of phenanthrene into water for laminar flow condition 显示文摘 | Grimberg S J Miller C T Aitken M D | 1996 | Environ Sci Technol1996，30，10： | 1 |
| 11 | Impact of oxidative stress on the health and immune function of dairy cattle 显示文摘 | Sordillo L M Aitken S L | 2009 | Vet Immunol Immunop2009，128，： | 1 |
| 12 | Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa显示文摘 | BAKER M A HETHERINGTON L AITKEN R J | 2006 | J Cell Sci2006，119，15： | 1 |
| 13 | Effect of neonatal handling on age-related impairments associated with the hippocampus显示文摘 | MEANEY M J AITKEN D H VAN BERKEL C | 1988 | Science1988，239，48411： | 1 |
| 14 | Annual dose conversion factors for TL and ESR dating显示文摘 | Nambi K S V Aitken M J | 1986 | Archacometry1986，28，： | 1 |
| 15 | A genetic linkage map in autotetraploid lucerne adapted to northern Australia, and use of the map to identify DNA markers linked to resistance to Phytophthora medicaginis显示文摘 | Musial J M Aitken K S Mackie J M | 2005 | Australian Journal of Agricultural Research2005，56，： | 1 |
| 16 | The gene encoding thephosphatidylinositol transfer protein is essential for cell growth 显示文摘 | AITKEN J F VAN HEUSDEN G P TEMKIN M | 1990 | The Journal of Biological Chemistry1990，265，： | 1 |
| 17 | Vitamin-E supplements and their effect on vitamin-E status in blood and genetic damage rate in peripheral blood lymphocytes显示文摘 | Fenech M Dreosti I Aitken C | 1997 | Carcinogenesis1997，18，： | 1 |
| 18 | Analysis of sequential aliquots of hypertonic saline solution-induced sputum from clinically stable patients with cystic fibrosis 显示文摘 | AITKEN M L GREENE K E TONELLI M R | 2003 | Chest2003，123，： | 1 |
| 19 | Lucerne genetic improvement for quantitatively inherited anthracnose (Colletotrichum trifolii) resistance facilitated by molecular markers显示文摘 | Irwin J A G Aitken K S Mackie J M | 2006 | Australian Plant Pathology2006，35，： | 1 |
| 20 | 14-3-3 proteins in neurodegenera- tion显示文摘 | Steinacker P Aitken A Otto M | 2011 | Semin Cell Dev Biol2011，22，： | 1 |
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