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| 1 | Hepatoprotective activity of Sapindus mukorossi and Rheum emodi extracts: In vitro and in vivo studies显示文摘AIM: To study the hepatoprotective capacity of Sapindus mukorossi (S. mukorossi) and Rheum emodi (R. emodi) extracts in CCl4 treated male rats. METHODS: The dried powder of S. mukorossi and R. emodi was extracted successively with petroleum ether, benzene, chloroform, and ethanol and concentrated in vacuum. Primary rat hepatocyte monolayer cultures were used for in vitro studies. In vivo, the hepatoprotective capacity of the extract of the fruit pericarp of S. mukorossi and the rhizomes of R. emodi was analyzed in liver injured CCl4-treated male rats. RESULTS: In vitro: primary hepatocytes monolayer cultures were treated with CCl4 and extracts of S. mukorossi & R. emodi. A protective activity could be demonstrated in the CCl4 damaged primary monolayer culture. In vivo : extracts of the fruit pericarp of S. mukorossi (2.5 mg/mL) and rhizomes of R. emodi (3.0 mg/mL) were found to have protective properties in rats with CCl4 induced liver damage as judged from serum marker enzyme activities. CONCLUSION: The extracts of S. mukorossi and R. emodi do have a protective capacity both in vitro on primary hepatocytes cultures and in in vivo in a rat model of CCl4 mediated liver injury. | Mohammed Ibrahim Mohammed Nane Khaja Anjum Aara Aleem Ahmed Khan Mohammed Aejaz Habeeb Yalavarthy Prameela Devi Mangamoori Lakshmi Narasu Chitoor Mohammed Habibullah | 2008 | World Journal of Gastroenterology2008，14，16： | 24 |
| 2 | A survey on trust based detection and isolation of malicious nodes in ad-hoc and sensor networks显示文摘 | Adnan AHMED Kamalrulnizam ABU BAKAR Muhammad Ibrahim CHANNA Khalid HASEEB Abdul Waheed KHAN | 2015 | Frontiers of Computer Science2015，9，2： | 15 |
| 3 | Effect of alternative antibiotics in treatment of cefotaxime resistant spontaneous bacterial peritonitis显示文摘AIM:To evaluate effective alternative antibiotics in treatment of cefotaxime-resistant spontaneous bacterial peritonitis.METHODS:One hundred cirrhotic patients with spontaneous bacterial peritonitis [ascitic fluid polymorphonuclear cell count(PMNLs) ≥ 250 cells/mm 3 at admission] were empirically treated with cefotaxime sodium 2 g/12 h and volume expansion by intravenous human albumin.All patients were subjected to history taking,complete examination,laboratory tests(including a complete blood cell count,prothrombin time,biochemical tests of liver and kidney function,and fresh urine sediment),chest X-ray,a diagnostic abdominal paracentesis,and the sample subjected to total and differential cell count,chemical examination,aerobic and anaerobic cultures.Patients were divided after 2 d by a second ascitic PMNL count into group Ⅰ;patients sensitive to cefotaxime(n = 81),group Ⅱ(n = 19);cases resistant to cefotaxime(less than 25% decrease in ascitic PMNL count).Patients of group Ⅱ were randomly assigned into meropenem(n = 11) or levofloxacin(n = 8) subgroups.All patients performed an end of treatment ascitic PMNL count.Patients were considered improved when:PMNLs decreased to < 250 cells/mm 3,no growth in previously positive culture cases,and improved clinical manifestations with at least 5 d of antibiotic therapy.RESULTS:Age,sex,and Child classes showed no significant difference between group Ⅰ and group Ⅱ.Fever and abdominal pain were the most frequent manifestations and were reported in 82.7% and 80.2% of patients in group Ⅰ and in 94.7% and 84.2% of patients in group Ⅱ,respectively.Patients in group Ⅱ had a more severe ascitic inflammatory response than group Ⅰ and this was demonstrated by more ascitic lactate dehydrogenase(LDH) [median:540 IU/L(range:150-1200 IU/L) vs median:240 IU/L(range:180-500 IU/L),P = 0.000] and PMNL [median:15 000 cell/mm 3(range:957-23 822 cell/mm 3) vs 3400 cell/mm 3(range:695-26 400 cell/mm 3),P = 0.000] counts.Ascitic fluid culture was positive in 32% of cases.Cefotaxime failed in 19% of patients;of these patients,11(100%) responded to meropenem and 6(75%) responded to levofloxacin.Two patients with failed levofloxacin therapy were treated according to the in vitro culture and sensitivity(one case was treated with vancomycin and one case was treated with ampicillin/sulbactam).In group Ⅱ the meropenem subgroup had higher LDH(range:108-860 IU/L vs 120-491 IU/L,P = 0.042) and PMNL counts(range:957-23 822 cell/mm 3 vs 957-15 222 cell/mm 3,P = 0.000) at initiation of the alternative antibiotic therapy;there was no significant difference in the studied parameters between patients responsive to meropenem and patients responsive to levofloxacin at the end of therapy(mean ± SD:316.01 ± 104.03PMNLs/mm 3 vs 265.63 ± 69.61 PMNLs/mm 3,P = 0.307).The isolated organisms found in group Ⅱ were;enterococci,acinetobacter,expanded-spectrum β-lactamase producing Escherichia coli,β-lactamase producing Enterobacter and Staphylococcus aureus.CONCLUSION:Empirical treatment with cefotaxime is effective in 81% of cases;meropenem is effective in cefotaxime-resistant cases. | Ahmed Abouelkhair Badawy Tarik Ibrahim Zaher Samar Mahmoud Sharaf Mohamed Hassan Emara Noha Elsaid Shaheen Talaat Fathy Aly | 2013 | World Journal of Gastroenterology2013，19，8： | 13 |
| 4 | Effect of Aging on the Toughness of Austenitic and Duplex Stainless Steel Weldments显示文摘In the present study,the effect of aging heat treatment at 650,750,and 850?C on the impact toughness of 316L austenitic stainless steel,2205 duplex stainless steel and their weldments has been investigated.Welding process was conducted using the TIG(tungsten inert gas) welding technique.Instrumented impact testing,at room temperature,was employed to determine the effect of aging treatment on the impact properties of investigated materials.Aging treatment resulted in degradation in the impact toughness as demonstrated by the reduction in the impact fracture energy and deformation parameters(strain hardening capacity,fracture deffection,and crack initiation and propagation energy).The degree of embrittlement was more noticeable in duplex stainless steel parent and weld-metal than in 316L stainless steel and became greater with the increase of aging temperature.The degradation in impact toughness was discussed in relation to the observed precipitation of the intermetallic sigma phase in the microstructure of the stainless steel weldments and the corresponding fracture surface morphology. | Omyma Hassan Ibrahim Ibrahim Soliman Ibrahim Tarek Ahmed Fouad Khalifa | 2010 | Journal of Materials Science & Technology2010，26，9： | 12 |
| 5 | Age distribution,polyps and rectal cancer in the Egyptian population-based cancer registry显示文摘AIM:To describe the clinical and epidemiologic profiles of the disease and to compare the findings with those generated from the previous hospital-based studies.METHODS:The Gharbiah cancer registry is the only population-based cancer registry in Egypt since 1998.We analyzed the data of all colorectal cancer patients included in the registry for the period of 1999-2007.All medical records of the 1364 patients diagnosed in Gharbiah during the study period were retrieved and the following information abstracted:age,residence,diagnosis date,grade,stage,topology,clinical characteristics,and histology variables.Egyptian census data for 1996 and 2006 were used to provide the general population's statistics on age,sex,residence and other related demographic factors.In addition to age-and sex-specific incidence rate analyses,we analyze the data to explore the incidence distribution by rural-urban differences among the 8 districts of the province.We also compared the incidence rates of Gharbiah to the rates of the Surveillance Epidemiology and End Results(SEER) data of the United States.RESULTS:Over the 9 year-period,1364 colorectal cancer cases were included.The disease incidence under age 40 years was relatively high(1.3/10 5) while the incidence in the age groups 40 and over was very low(12.0/10 5,19.4/10 5 and 21.2/10 5 in the age groups 40-59 years,60-69 years and > 70 years,respectively).The vast majority of tumors(97.2%) had no polyps and 37.2% of the patients presented with primary lesions in the rectum.Colorectal cancer was more common in patients from urban(55%) than rural(45%) areas.Regional differences in colon and rectal cancer incidence in the 8 districts of the study province may reflect different etiologic patterns in this population.The registry data of Egypt shows a slightly higher incidence of colorectal cancer than the United States in subjects under age 40 years.The results also shows significantly lower incidence of colorectal cancer in subjects over age 40 years compared to the same age group in the United States SEER.CONCLUSION:Low rate of polyps,low incidence in older subjects,and high rate of rectal cancer in Egypt.Future studies should explore clinical and molecular disease patterns. | Darlene Veruttipong Amr S Soliman Samuel F Gilbert Taylor S Blachley Ahmed Hablas Mohamed Ramadan Laura S Rozek Ibrahim A Seifeldin | 2012 | World Journal of Gastroenterology2012，18，30： | 12 |
| 6 | 太阳活动峰年和谷年期间黑子群与耀斑的统计分析显示文摘基于NOAA/SWPC公布的太阳活动数据,我们选取第24太阳活动峰年附近的12个连续月份(2011年7月至2012年6月)和第23太阳活动周谷年附近的12个连续月份(2005年7月至2006年6月),统计了这两段时间中太阳黑子群和耀斑的活动规律,并根据时间、黑子群分布纬度、寿命和磁场类型等对峰年和谷年进行了详细分析和比较,主要结论如下所述.(1)黑子群数随时间的变化在峰年和谷年均比较随机,峰年期间黑子数比谷年增多1.5倍左右.耀斑爆发与黑子群活动具有良好的相关性,但峰年期间存在某个月份耀斑数很少的现象,而谷年期间存在某个月份耀斑数集中增多的现象.(2)无论峰年还是谷年,δ类型黑子群的耀斑产率(耀斑总数与黑子群总数之比)最大,但β型黑子群产生的耀斑爆发最多.耀斑产率与磁场类型有密切关系,但与其所处太阳活动周中的阶段无关.(3)黑子群和耀斑的纬度分布的南北不对称性,以X级耀斑最为显著.峰年较谷年的耀斑数增加主要集中在C级和M级.(4)耀斑产率同黑子群寿命具有良好的相关性,但黑子群的数目同它们的寿命之间没有明显的规律. | 赵明宇 陈军权 刘煜 IBRAHIM Ahmed 闫晓理 敦金平 | 2014 | 中国科学:物理学、力学、天文学2014，44，1： | 12 |
| 7 | Ultrasound-guided transrectal extended prostate biopsy:a prospective study显示文摘Aim: To evaluate the diagnostic value of the 10 systematic transrectal ultrasound-guided (TRUS) prostate biopsy compared with the sextant biopsy technique for patients with suspected prostate cancer. Methods: One hundred and fifty-two patients with suspected prostate cancer were included in the study. Patients were entered in the study because they presented with high levels of prostate specific antigen (PSA) (over 4ng/mL) and/or had undergone an abnormal digital rectal examination (DRE). In addition to sextant prostate biopsy cores, four more biopsies were obtained from the lateral peripheral zone with additional cores from each suspicious area revealed by transrectal ultrasound. Sextant, lateral peripheral zone and suspicious area biopsy cores were submitted separately to the pathological department. Results: Cancer detection rates were 27.6%(42/152) and 19.7%(30/152) for the 10-core and sextant core biopsy protocols, respectively. Adding the lateral peripheral zone (PZ) to the sextant prostate biopsy showed a 28.6%(12/42) increase in the cancer detection rate in patients with positive prostate cancer (P<0.01).The cancer detection rate in patients who presented with elevated PSA was 29.3%(34/116). When serum PSA was 4-10ng/mL TRUS-guided biopsy detected cancer in 20.6%, while the detection rate was 32.4% and 47.0% when serum PSA was 10-20ng/mL and above 20ng/mL, respectively. Conclusion: The 10 systematic TRUS-guided prostate biopsy improves the detection rate of prostate cancer by 28.6% when compared with the sextant biopsy technique alone, without increase in the morbidity. We therefore recommend the 10-core biopsy protocol to be the preferred method for early detection of prostate cancer. | Mohammed Ahmed Al-Ghazo Ibrahim Fathi Ghalayini Ismail Ibrahim Matalka | 2005 | Asian Journal of Andrology2005，7，2： | 10 |
| 8 | Soil salinity prediction in the Lower Cheliff plain(Algeria) based on remote sensing and topographic feature analysis显示文摘Soil salinity and ground surface morphology in the Lower Cheliff plain(Algeria) can directly or indirectly impact the stability of environments. Soil salinization in this area is a major pedological problem related to several natural factors, and the topography appears to be important in understanding the spatial distribution of soil salinity. In this study, we analyzed the relationship between topographic parameters and soil salinity, giving their role in understanding and estimating the spatial distribution of soil salinity in the Lower Cheliff plain. Two satellite images of Landsat 7 in winter and summer 2013 with reflectance values and the digital elevation model(DEM) were used. We derived the elevation and slope gradient values from the DEM corresponding to the sampling points in the field. We also calculated the vegetation and soil indices(i.e. NDVI(normalized difference vegetation index), RVI(ratio vegetation index), BI(brightness index) and CI(color index)) and soil salinity indices, and analyzed the correlations of soil salinity with topography parameters and the vegetation and soil indices. The results showed that soil salinity had no correlation with slope gradient, while it was significantly correlated with elevation when the EC(electrical conductivity) values were less than 8 d S/m. Also, a good relationship between the spectral bands and measured soil EC was found, leading us to define a new salinity index, i.e. soil adjusted salinity index(SASI). SASI showed a significant correlation with elevation and measured soil EC values. Finally, we developed a multiple linear regression for soil salinity prediction based on elevation and SASI. With the prediction power of 45%, this model is the first one developed for the study area for soil salinity prediction by the combination of remote sensing and topographic feature analysis. | Ibrahim YAHIAOUI Abdelkader DOUAOUI ZHANG Qiang Ahmed ZIANE | 2015 | Journal of Arid Land2015，7，6： | 9 |
| 9 | 观测站有位置误差的多维标度时频差定位算法显示文摘定位精度对观测站位置误差很敏感。论文针对观测站位置和速度有误差的情况,提出了一种加权多维标度时频差定位算法。该算法利用了多维标度定位通过特征结构和维度信息抑制噪声的优势,它将定位残差表示成测量误差和观测站位置误差的线性形式,然后通过加权最小二乘给出了目标位置和速度估计的闭式解。仿真结果表明,在小的测量误差和观测站位置误差时,该算法对目标位置和速度的估计能够达到克拉美劳下界。与两步加权最小二乘和约束总体最小二乘算法相比,该算法在测量噪声和观测站位置误差较大时有更高的定位精度。 | 曹景敏 万群 欧阳鑫信 邹延宾 Hesham Ibrahim Ahmed | 2017 | 信号处理2017，33，1： | 9 |
| 10 | History of cupping(Hijama):a narrative review of literature显示文摘Cupping(Hijama in Arabic) is an ancient, holistic method for the treatment of a variety of diseases. Though the exact origin of cupping therapy is a matter of controversy, its use has been documented in early Egyptian and Chinese medical practices. Diverse human civilizations have contributed to the historical development and continuation of cupping therapy. This narrative review describes the history of cupping, historical definitions, cupping instruments and uses of cupping therapy. Electronic searches of relevant databases(Pub Med, Google Scholar and Ovid SP) were conducted using keywords and Boolean operators. Manual searches and references of published articles and books were also conducted. A number of articles(N = 625) were retained for extensive review, and finally 83 articles were included in this paper. The historical descriptions of cupping therapy were found in ancient human civilizations of the Eastern and Western world. There were inconsistent data concerning the origin of cupping, definitions, instruments, procedures, definite advancements and research in Hijama over centuries. Cupping therapy fell out of favor in 17 th and mid-18 th centuries but recovered popularity in modern medicine. Currently, cupping therapy is used for health promotion, prophylaxis and treatment of a variety of diseases around the world. Cupping therapy with a good safety profile has a checkered history and is a well-recognized traditional method for managing medical conditions. Currently, the scope of cupping therapy is expanding, and a growing body of research is providing additional evidence-based data for the further advancement of cupping therapy in the treatment of a variety of diseases. | Naseem Akhtar Qureshi Gazzaffi Ibrahim Ali Tamer Shaban Abushanab Ahmed Tawfik El-Olemy Meshari Saleh Alqaed Ibrahim S. EI-Subai Abdullah M.N. AI-Bedah | 2017 | Journal of Integrative Medicine2017，15，3： | 4 |
| 11 | Differential expression of cell cycle regulators in HCV-infection and related hepatocellular carcinoma显示文摘AIM:To investigate cell cycle proteins in chronic hepatitis C virus infection in order to analyze their role in the process of hepatocyte transformation and to characterize their prognostic properties. METHODS:Subjects of the current study included 50 cases of chronic hepatitis C(CHC) without cirrhosis,30 cases of CHC with liver cirrhosis(LC) ,and 30 cases of hepatitis C-related hepatocellular carcinoma(HCC) admitted to the Department of Hepato-Gastroenterology,Theodor Bilharz Research Institute(TBRI) ,Giza,Egypt.Fifteen wedge liver biopsies,taken during laparoscopic cholecystectomy,were also included as normal controls.Laboratory investigations including urine and stool analysis,liver function tests and prothrombin concentration;serologic markers for viral hepatitis and ultrasonography were done for all cases of the study together with immunohistochemical analysis using primary antibodies against Cyclin D1,Cyclin E,p21,p27 and Rb/p105 proteins. RESULTS:Normal wedge liver biopsies didn't express Cyclin E or Rb/p105 immunostaining but show positive staining for Cyclin D1,p21 and p27.Cyclin D1 expressed nuclear staining that was sequentially increased from CHC to LC(P<0.01) to HCC(P<0.001) cases;meanwhile,Cyclin E revealed nuclear positivity only in the case of HCCs patients that was directly correlated to Rb/p105 immuno-reactivity.The expression of p21 and p27 was significantly increased in CHC and LC cases compared to normal controls and HCCs with no significant difference between well-and poorlydifferentiated tumors.p21 showed only a nuclear pattern of staining,while,p27 presented with either cytoplasmic and/or nuclear reactivity in all studied cases.Correlation analysis revealed a direct relation between Cyclin D1 and p21 in CHC cases(P<0.001) ,between Cyclin D1 and Cyclin E in HCCs(P<0.01);however,an inverserelationship was detected between Cyclin D1 and p21 or p27(P<0.001) and between p21 and Rb/p105(P<0.05) in HCCs. CONCLUSION:Upregulation of Cyclin D1 in CHC plays a vital role in the development and differentiation of HCC;while,Cyclin E may be a useful marker for monitoring tumor behavior.p21 and p27 can be used as predictive markers for HCC.Furthermore,higher expression of Rb/p105 as well as inverse relation with p21 and histologic grades suggests its important role in hepatic carcinogenesis. | Azza E El Bassiouny Mona M Nosseir Mona K Zoheiry Noha A Ameen Ahmed M Abdel-Hadi Ibrahim M Ibrahim Suher Zada Abdel-Hakeem Saad El-Deen Nora E El-Bassiouni | 2010 | World Journal of Hepatology2010，2，1： | 3 |
| 12 | Post-Percutaneous Nephrolithotomy Extensive Hemorrhage: A Study of Risk Factors显示文摘 | Ahmed R. El-Nahas Ahmed A. Shokeir Ahmed M. El-Assmy Tarek Mohsen Ahmed M. Shoma Ibrahim Eraky Mahmoud R. El-Kenawy Hamdy A. El-Kappany | 2007 | The Journal of Urology2007，，2： | 3 |
| 13 | Activated Anilide in Heterocyclic Synthesis: Synthesis of New Dihydropyridines, Dihydropyridazines and Thiourea Derivatives显示文摘一系列新 dihydropyridines, butanamide, dihydropyridazines 和 thiourea 衍生物通过 3-aminopyridine (1 ) 和 N-(pyridin-3-yl )-3-(pyridin-3-ylimino)butanamide 的反应被准备了 3 与一些 electrophilic 试剂,芳基重氮基盐和 isothiocyanates。基本分析, MS,红外,和 1H NMR 系列证实了产品的身份。 | Hafiz, Ibrahim S. A. Ramiz, Mahmoud M. M. Sarhan, Ahmed A. M. | 2011 | Chinese Journal of Chemistry2011，29，6： | 3 |
| 14 | Fulminant hepatic failure caused by Salmonella paratyphi A infection显示文摘我们报导暴发性的肝的失败的一个案例把感染与沙门氏菌 paratyphi 联系了,在进入有二天的发烧的特别护理单位(ICU ) 的一个 29 岁的病人,头疼并且呕吐列在后面由行为变化和丧失方向感。在检查上,病人显得尖锐地病了,鼓动,糊涂,并且深深地 jaundiced。C 的温度 38.5 度,脉搏 92/min,血压 130/89 毫米汞柱。血的两件样品种了 S。paratyphi A,它对 ceftriaxone 和 ciprofloxacin 敏感。Ceftriaxon 与高剂量的地塞米松被管理。有 ceftriaxon 的二星期术后疗法,病人处于令人满意的状况被解除。 | Fahmi Yousef Khan Ahmed A Kamha Ibrahim Y Alomary | 2006 | World Journal of Gastroenterology2006，12，32： | 3 |
| 15 | Tumor necrosis factor-α-G308A polymorphism is associated with liver pathological changes in hepatitis C virus patients显示文摘AIM To investigate the association of tumor necrosis factor alpha(TNFα)-G308 A polymorphism with different liver pathological changes in treatment-na?ve Egyptian patients infected with hepatitis C virus(HCV) genotype 4.METHODS This study included 180 subjects,composed of 120 treatment-na?ve chronic HCV patients with different fibrosis grades(F0-F4) and 60 healthy controls. The TNFα-G308 A region was amplified by PCR and the different genotypes were detected by restriction fragment length polymorphism analysis. The TNFα protein was detected by enzyme-linked immunosorbent assay. The influence of different TNFα-G308 A genotypes on TNFα expression and liver disease progression were statistically analyzed. The OR and 95%CI were calculated to assess the relative risk confidence.RESULTS Current data showed that the TNFα-G308 A SNP frequency was significantly different between controls and HCV infected patients(P = 0.001). Both the AA genotype and A allele were significantly higher in late fibrosis patients(F2-F4,n = 60) than in early fibrosis patients(F0-F1,n = 60)(P = 0.05,0.04 respectively). Moreover,the GA or AA genotypes increased the TNFα serum level greater than the GG genotype(P = 0.002). The results showed a clear association between severe liver pathological conditions(inflammation,steatosis and fibrosis) and(GA + AA) genotypes(P = 0.035,0.03,0.04 respectively). The stepwise logistic regression analysis showed that the TNFα genotypes(GA + AA) were significantly associated with liver inflammation(OR = 3.776,95%CI: 1.399-10.194,P = 0.009),severe steatosis(OR = 4.49,95%CI: 1.441-14.0,P = 0.010) and fibrosis progression(OR = 2.84,95%CI: 1.080-7.472,P = 0.034). Also,the A allele was an independent risk factor for liver inflammation(P = 0.003),steatosis(P = 0.003) and fibrosis(P = 0.014). CONCLUSION TNFα SNP at nucleotide-308 represents an important genetic marker that can be used for the prognosis of different liver pathological changes in HCV infected | Noha G Bader El Din Sally Farouk Reem El-Shenawy Marwa K Ibrahim Reham M Dawood Mostafa M Elhady Ahmed M Salem Naglaa Zayed Ahmed Khairy Mostafa K El Awady | 2016 | World Journal of Gastroenterology2016，22，34： | 3 |
| 16 | 土体等向固结曲线的Logistic模型显示文摘基于非饱和土等向压缩试验和Logistic函数,提出了一种土体等向固结曲线的模型。首先,对目前土体体变方程中常用的单对数和双对数线性模型的不足进行了分析;然后,借助Logistic函数,建立了各向等压条件下的土体孔隙比和压力模型,并给出了模型中各参数的确定方法以及前期固结压力的解析表达;最后,通过与已有试验数据进行对比,验证了该模型的有效性,分析了各参数随非饱和土中吸力的变化规律。 | 周凤玺 邵彦平 MUSA Abdallah Ibrahim Ahmed | 2020 | 岩土工程学报2020，42，5： | 2 |
| 17 | Climate change impact and adaptation on wheat yield, water use and water use efficiency at North Nile Delta显示文摘Investigation of climate change impacts on food security has become a global hot spot.Even so,efforts to mitigate these issues in arid regions have been insufficient.Thus,in this paper,further research is discussed based on data obtained from various crop and climate models.Two DSSATcrop models(CMs)(CERESWheat and N-Wheat)were calibrated with two wheat cultivars(Gemiza9 and Misr1).A baseline simulation(1981-2010)was compared with different scenarios of simulations using three Global Climate Models(GCMs)for the 2030s,2050s and 2080s.Probable impacts of climate change were assessed using the GCMs and CMs under the high emission Representative Concentration Pathway(RCP8.5).Results predicted decreased wheat grain yields by a mean of 8.7%,11.4%and 13.2%in the 2030s,2050s and 2080s,respectively,relative to the baseline yield.Negative impacts of climatic change are probable,despite some uncertainties within the GCMs(i.e.,2.1%,5.0%and 8.0%)and CMs(i.e.,2.2%,6.0%and 9.2%).Changing the planting date with a scenario of plus or minus 5 or 10 days from the common practice was assessed as a potentially effective adaptation option,which may partially offset the negative impacts of climate change.Delaying the sowing date by 10 days(from 20 November to 30 November)proved the optimum scenario and decreased further reduction in wheat yields resulting from climate change to 5.2%,6.8%and 8.5%in the 2030s,2050s and 2080s,respectively,compared with the 20 November scenario.The planting 5-days earlier scenario showed a decreased impact on climate change adaptation.However,the 10-days early planting scenario increased yield reduction under projected climate change.The cultivar Misr1 was more resistant to rising temperature than Gemiza9.Despite the negative impacts of projected climate change on wheat production,water use efficiency would slightly increase.The ensemble of multi-model estimated impacts and adaptation uncertainties of climate change can assist decision-makers in planning climate adaptation strategies. | Marwa Gamal Mohamed Ali Mahmoud Mohamed Ibrahim Ahmed El Baroudy Michael Fullen El-Said Hamad Omar Zheli Ding Ahmed Mohammed Saad Kheir | 2020 | Frontiers of Earth Science2020，14，3： | 2 |
| 18 | Toxicity assessment of polyethylene microplastics in combination with a mix of emerging pollutants on Physalaemus cuvieri tadpoles显示文摘Studies in recent years have shown that aquatic pollution by microplastics(MPs)can be considered to pose additional stress to amphibian populations.However,our knowledge of how MPs affect amphibians is very rudimentary,and even more limited is our understanding of their effects in combination with other emerging pollutants.Thus,we aimed to evaluate the possible toxicity of polyethylene MPs(PE-MPs)(alone or in combination with a mix of pollutants)on the health of Physalaemus cuvieri tadpoles.After 30 days of exposure,multiple biomarkers were measured,including morphological,biometric,and developmental indices,behavioral parameters,mutagenicity,cytotoxicity,antioxidant and cholinesterase responses,as well as the uptake and accumulation of PE-MPs in animals.Based on the results,there was no significant change in any of the parameters measured in tadpoles exposed to treatments,but induced stress was observed in tadpoles exposed to PE-MPs combined with themixture of pollutants,reflecting significant changes in physiological and biochemical responses.Through principal component analysis(PCA)and integrated biomarker response(IBR)assessment,effects induced by pollutants in each test group were distinguished,confirming that the exposure of P.cuvieri tadpoles to the PE-MPs in combination with a mix of emerging pollutants induces an enhanced stress response,although the uptake and accumulation of PE-MPs in these animalswas reduced.Thus,our study provides newinsight into the danger to amphibians of MPs coexisting with other pollutants in aquatic environments. | Amanda Pereira da Costa Araújo Thiarlen Marinho da Luz Mohamed Ahmed Ibrahim Ahmed Mir Mohammad Ali Md.Mostafizur Rahman Bojan Nataraj Daniela de Melo e Silva DamiàBarceló Guilherme Malafaia | 2023 | Journal of Environmental Sciences2023，，5： | 2 |
| 19 | Isolated antibody to hepatitis B core antigen in patients with chronic hepatitis C virus infection显示文摘瞄准:与长期的丙肝在病人评估孤立的 anti-HBc 的流行病毒(HCV ) 感染,和它与疾病严厉的关系。方法:我们屏蔽了所有病人,长期的 HCV 感染指了肝炎 B 表面抗原(HBsAg ) 的法萨尔国王专家医院和研究中心,到肝炎 B 表面抗原(anti-HBs ) 的抗体,和 anti-HBc。为 HBsAg 和 anti-HBs 测试了 negative 的一百和 69 个病人在这研究被包括。结果:病理地, 59 有证明活体检视的肝硬化和 110 有的长期的活跃肝炎(CAH ) 。这 169 个病人,(50.3%) 85 测试了为 anti-HBc 积极。有 CAH 的病人与肝硬化比病人有孤立的 anti-HBc 的显著地更高的流行, 71 (64.5%) 并且 14 (23.7%) 分别地(P <
0.001 ) 。25 个病人被质的 PCR 为 HBV DNA 测试。测试在他们中的 3 个是阳性的(12% ;秘密 HBV 感染) 。结论:孤立的 anti-HBc 独自在有长期的 HCV 感染的沙特阿拉伯的病人是普通的,并且是显著地在那些更普通与 CAH 比那些与肝硬化。因此,仅仅在这些病人为 HBsAg 和 anti-HBs 测试的屏蔽策略将错过可能潜在地传染的有孤立的 anti-HBc 的很多个人。 | Ahmed Helmy Mohammed Ibrahim Al-Sebayel | 2006 | World Journal of Gastroenterology2006，12，27： | 2 |
| 20 | Novel non-invasive biological predictive index for liver fibrosis in hepatitis C virus genotype 4 patients显示文摘AIM To investigate the diagnostic ability of a non-invasive biological marker to predict liver fibrosis in hepatitis C genotype 4 patients with high accuracy.METHODS A cohort of 332 patients infected with hepatitis C genotype 4 was included in this cross-sectional study. Fasting plasma glucose, insulin, C-peptide, and angiotensinconverting enzyme serum levels were measured. Insulin resistance was mathematically calculated using the homeostasis model of insulin resistance(HOMA-IR).RESULTS Fibrosis stages were distributed based on Metavir score as follows: F0 = 43, F1 = 136, F2 = 64, F3 = 45 and F4 = 44. Statistical analysis relied upon reclassification of fibrosis stages into mild fibrosis(F0-F) = 179, moderate fibrosis(F2) = 64, and advanced fibrosis(F3-F4) = 89. Univariate analysis indicated that age, log aspartate amino transaminase, log HOMA-IR and log platelet count were independent predictors of liver fibrosis stage(P < 0.0001). A stepwise multivariate discriminant functional analysis was used to drive a discriminative model for liver fibrosis. Our index used cut-off values of ≥ 0.86 and ≤-0.31 to diagnose advanced and mild fibrosis, respectively, with receiving operating characteristics of 0.91 and 0.88, respectively. The sensitivity, specificity, positive predictive value, negative predictive value and positive likelihood ratio were: 73%, 91%, 75%, 90% and 8.0 respectively for advanced fibrosis, and 67%, 88%, 84%, 70% and 4.9, respectively, for mild fibrosis.CONCLUSION Our predictive model is easily available and reproducible, and predicted liver fibrosis with acceptable accuracy. | Mahmoud Khattab Mohamed Amin Sakr Mohamed Abdel Fattah Youssef Mousa Elwy Soliman Ashraf Breedy Mona Fathi Salwa Gaber Ahmed Altaweil Ashraf Osman Ahmed Hassouna Ibrahim Motawea | 2016 | World Journal of Hepatology2016，8，32： | 2 |
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