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| 1 | Short and long term prognosis in perinatal asphyxia: An update显示文摘Interruption of blood flow and gas exchange to the fetus in the perinatal period, known as perinatal asphyxia, can, if significant, trigger a cascade of neuronal injury, leading on to neonatal encephalopathy(NE) and resultant long-term damage. While the majority of infants who are exposed to perinatal hypoxia-ischaemia will recover quickly and go on to have a completely normal survival, a proportion will suffer from an evolving clinical encephalopathy termed hypoxic-ischaemic encephalopathy(HIE) or NE if the diagnosis is unclear. Resultant complications of HIE/NE are wide-ranging and may affect the motor, sensory, cognitive and behavioural outcome of the child. The advent of therapeutic hypothermia as a neuroprotective treatment for those with moderate and severe encephalopathy has improved prognosis. Outcome prediction in these infants has changed, but is more important than ever, as hypothermia is a time sensitive intervention, with a very narrow therapeutic window. To identify those who will benefit from current and emerging neuroprotective therapies we must be able to establish the severity of their injury soon after birth. Currently available indicators such as blood biochemistry, clinical examination and electrophysiology are limited. Emerging biological and physiological markers have the potential to improve our ability to select those infants who will benefit most from intervention. Biomarkers identified from work in proteomics, metabolomics and transcriptomics as well as physiological markers such as heart rate variability, EEG analysis and radiological imaging when combined with neuroprotective measures have the potential to improve outcome in HIE/NE. The aim of this review is to give an overview of the literature in regards to short and longterm outcome following perinatal asphyxia, and to discuss the prediction of this outcome in the early hours after birth when intervention is most crucial; looking at both currently available tools and introducing novel markers. | Caroline E Ahearne Geraldine B Boylan Deirdre M Murray | 2016 | World Journal of Clinical Pediatrics2016，5，1： | 16 |
| 2 | 全球国际收支失衡:欧洲的观点显示文摘 | Alan Ahearne Klaus Regling In Jun Kim Dariusz Rosati 施建淮 | 2006 | 国际经济评论2006，，5： | 5 |
| 3 | Metal Construction显示文摘 | Ahearn J S | 1982 | 14(4): 192-1971982，14，4： | 1 |
| 4 | Behavioural disorders, disability and quality of life in Parkinson' s disease显示文摘 | Leroi I Ahearn D J Andrews M | 2011 | Age Ageing2011，40，： | 1 |
| 5 | The outcome following fixa- tion of bicondylar tibial plateau fractures 显示文摘 | Ahearn N Oppy A Halliday R | 2014 | Bone Joint J2014，96，7： | 1 |
| 6 | Purine derivatives as potent gamma-secretase modulators 显示文摘 | RIVKIN A AHEARN S P CHICHETTI S M | 2010 | Bioorg Med Chem Lett2010，20，7： | 1 |
| 7 | A Comparison of the SPOT and landsat thematic mapper satellite systems for detecting gypsy moth defoliation in Michigan显示文摘 | JORIA P E AHEARN S C | 1991 | Photogrammetric Engineering&Remote Sensing1991，57，12： | 1 |
| 8 | Structure and function of the complement receptors, CR1(CD35) and CR2(CD21)显示文摘 | Fearon DT | 1989 | Adv Immunol1989，46，： | 1 |
| 9 | Medical therapy for pulmonary arterial hypertension:updated ACCP evidence-based clinical practice guidelines显示文摘 | Badesch DB Abman SH Ahearn GS | 2007 | Chest2007，131，6： | 1 |
| 10 | Organizational citizenship behavior and the quantity and quality of work group performance显示文摘 | PODSKOFF P M AHEARNE M MACKENZIE S B | 1998 | Journal of Applied Psychology1998，，2： | 1 |
| 11 | Organizational citizenship behavior and the quantity and quality of work group performance显示文摘 | Podsakoff P M Ahearne M Mackenzie S B | 1998 | Journal of Applied Psychology1998，2，： | 1 |
| 12 | Antecedents and Conse- quences of Customer - Company Identification: Expanding the Role of Relationship Marketing 显示文摘 | Ahearne M Bhattacharya C Gruen T | 2005 | The Journal of Applied Psy- chology2005，90，： | 1 |
| 13 | Some possible antecedents of in-role and extra-role salesperson performance 显示文摘 | MACKENZIE S B PODSAKOFF P M AHEARNE M | 1998 | Journal of Marking1998，62，： | 1 |
| 14 | Piperazinyl pyrimidine derivatives as potent gamma-secretase modulators显示文摘 | RIVKIN A AHEARN S P CHICHETTI S M | 2010 | Bioorg Med Chem Lett2010，20，3： | 1 |
| 15 | Determination of the role for CD21 during Epstein-Barr virus infection of B-lymphoblastoid cells显示文摘 | Martin D Marlowe R Ahearn J | 1994 | J Virol1994，68，8： | 1 |
| 16 | A neuroanatomic model for depression显示文摘 | Byrum CE Ahearn EP Krishnan KR | 1999 | Prog Neuropsychopharmacol Biol Psychiatry1999，23，： | 1 |
| 17 | 显示文摘 | Davis G D Ahearn J S Matienzo L J | 1985 | Journal of Materials Science1985，20，： | 1 |
| 18 | Environmental durability of phosphoric acid anodized aluminium adhesive joints protected with hydration inhibitors显示文摘 | D. A. Hardwick J. S. Ahearn A. Desai J. D. Venables | 1986 | Journal of Materials Science1986，，1： | 1 |
| 19 | Resistance to brand switching when a radically new brand is introduced: A so- cial identity theory perspective 显示文摘 | Lain S K Ahearne M Hu Y | 2010 | Journal of Marketing2010，74，6： | 1 |
| 20 | Cardiovascular disease biomarkers across autoimmune diseases 显示文摘 | AHEARN J SHIELDS K J LIU C C | 2015 | Clinlmmunol2015，161，1： | 1 |
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