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6篇 您的检索式:作者名="Adarsh N"
    题名 作者 年代 出处 被引量
1显示文摘Sahoo P Adarsh N N Chaeko G E 2009Langmuir2009,25,15:1
2Efficient reaction based eolorimetric probe for sensitive detection, quantification, and on-site analysis of nitrite ions in nat- ural water resources显示文摘Adarsh N Shanmugasundaram M Ramaiah D 2013Analytical chemistry2013,85,10:1
3Tuning photosensitized singlet oxygen generation efficiency of novel aza-BODIPY dyes显示文摘Adarsh N Avirah RR Ramaiah D 2010Org Lett2010,12,24:1
4Determination of chlorpyrilos 20% EC in scented rose and its products显示文摘Ajay K Girecesh N Adarsh S 2004Chromatogr A2004,1050,:1
5Selective separation of the sulfate anion by in situ crystallization of Cd^Ⅱ coordination compounds derived from bis (pyridyl) ligands equipped with a urea/amide hydrogen-bonding backbone 显示文摘Banerjee S Adarsh N N Dastidar P 2010Eur J Inorg Chem2010,,:1
6Monitoring adenoviral based gene delivery in rat glioma by molecular imaging显示文摘AIM:To determine whether endothelial progenitor cells(EPCs)can be used as delivery vehicle for adenoviral vectors and imaging probes for gene therapy in glioblastoma.METHODS:To use cord blood derived EPCs as delivery vehicle for adenoviral vectors and imaging probes for glioma gene therapy,a rat model of human glioma was made by implanting U251 cells orthotopically.EPCs were transfected with an adenovirus(AD5/carrying hNIS gene)and labeled with iron oxide and inoculated them directly into the tumor 14 d following implantation of U251 cells.Magnetic resonance imaging(MRI)was used to in vivo track the migration of EPCs in the tumor.The expression of gene products was determined by in vivo Tc-99m single photon emission computed tomography(SPECT).The findings were validated with immunohistochemistry(IHC).RESULTS:EPCs were successfully transfected with the adenoviral vectors carrying hNIS which was proved by significantly(P<0.05)higher uptake of Tc-99m in transfected cells.Viability of EPCs following transfection and iron labeling was not altered.In vivo imaging showed the presence of iron positive cells and the expression of transgene(hNIS)product on MRI and SPECT,respectively,all over the tumors following administration of transfected and iron labeled EPCs in the tumors.IHC confirmed the distribution of EPC around the tumor away from the injection site and also showed transgene expression in the tumor.The results indicated the EPCs’ability to deliver adenoviral vectors into the glioma upon intratumor injection.CONCLUSION:EPCs can be used as vehicle to deliver adenoviral vector to glioma and also act as imaging probe at the same time.Nadimpalli Ravi S Varma Kenneth N Barton Branislava Janic Adarsh Shankar ASM Iskander Meser M Ali Ali S Arbab 2013World Journal of Clinical Oncology2013,4,4:0
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