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| 1 | 复杂场源形态的海洋可控源电磁三维正演显示文摘在使用电偶极发射源的可控源电磁法(CSEM)勘探中,发射源的方位、长度、形状等对观测数据有重要的影响,然而现有的大部分三维数值模拟方法没有全面地将这些因素考虑进来,很多都只能应对非常简单的场源形态,例如单一方位的点电偶极子,这有可能显著降低模拟结果的准确性.本文实现了基于交错网格有限体积(FV)离散的海洋CSEM三维正演算法,能够模拟形态相对复杂的场源,包括任意方位的有限长直导线和弯曲导线发射源.该算法使用一次场/二次场方法,只需对二次场使用FV法求解,避免了场源的奇异性问题;一次场的计算为一维正演问题,使用准解析法求解,并且只要在计算一次场时考虑复杂的场源形态便可以实现同样场源的三维正演.通过与一维理论模型的解析解对比验证了三维程序的准确性,并针对三维理论模型进行了一系列正演测试,初步考察了场源形态对三维正演结果的影响. | 韩波 胡祥云 Adam SCHULTZ 左博新 李建慧 蔡建超 | 2015 | 地球物理学报2015，58，3： | 32 |
| 2 | Combination therapy with androgen deprivation for hormone sensitive prostate cancer: A new frontier显示文摘Androgen deprivation therapy(ADT)has been the standard of care for the last 75 years in metastatic hormone sensitive prostate cancer(PCa).However,this approach is rarely curative.Recent clinical trials have demonstrated that ADT combined with other agents,notably docetaxel and abiraterone,lead to improved survival.The mechanisms surrounding this improved cancer outcomes are incompletely defined.The response of cancer cells to ADT includes apoptosis and cell death,but a significant fraction remains viable.Our laboratory has demonstrated both in vitro and in vivo that cellular senescence occurs in a subset of these cells.Cellular senescence is a phenotype characterized by cell cycle arrest,senescenceassociated b-galactosidase(SA-b-gal),and a hypermetabolic state.Positive features of cellular senescence include growth arrest and immune stimulation,although persistence may release cytokines and growth factors that are detrimental.Senescent tumor cells generate a catabolic state with increased glycolysis,protein turnover and other metabolic changes that represent targets for drugs,like metformin,to be applied in a synthetic lethal approach.This review examines the response to ADT and the putative role of cellular senescence as a biomarker and therapeutic target in this context. | Tyler Etheridge Shivashankar Damodaran Adam Schultz Kyle A.Richards Joseph Gawdzik Bing Yang Vincent Cryns David F.Jarrard | 2019 | Asian Journal of Urology2019，6，1： | 3 |
| 3 | Impact flash spectroscopy显示文摘 | Schultz P H Adams M A Perry J W | 1996 | Lunarand Planetary Science1996，27，3： | 1 |
| 4 | Spectroscopic measurements of vapor clouds due to oblique impacts显示文摘 | Sugita S Schultz P H Adams M A | 1998 | Journal of Geophysical Research1998，103，19： | 1 |
| 5 | A case history: Effects of mixing regime on nutrient dynamics and community structure in the Third Sister Lake, Michigan during late winter and early spring 2003显示文摘 | JUDD K E ADAMS H E BOSCH N S KOSTRZEWSKI J M SCOTT C E SCHULTZ B M WANG D H KLING G W | 2005 | Lake and Reservoir Management2005，21，： | 1 |
| 6 | Continuous localization using evidence grids显示文摘 | Schultz A C Adams W | 1998 | Robotics and Automation1998，，4： | 1 |
| 7 | Effects of epidermal growth factor,fibroblast growth factor,and transforming growth factor-beta on corneal cell chemotaxis显示文摘 | Grant MB Khaw PT Schultz GS Adams JL Shimizu RW | 1992 | Invest Ophthalmol Vis Sci1992，33，12： | 1 |
| 8 | Spectroscopic measurements of vapor clouds due to oblique impacts显示文摘 | Sugita S Schultz P H Adams M A | 1998 | Journal of Geophysical Re- search1998，103，19： | 1 |
| 9 | Impact flash spectroscopy显示文摘 | Schultz P H Adams M A Perry J W | 1996 | Lunar and Planetary Science1996，27，： | 1 |
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