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| 1 | 国际文摘——静脉畸形与局限性血管内凝血显示文摘静脉畸形是先天性低流速血管畸形.局限性血管内凝血(LIC)可导致疼痛及血栓形成,术中有发生大出血的危险。该文旨在确定易发生血管内凝血的静脉畸形的类型。对140例患者进行前瞻性研究,记录临床资料,测量凝血参数,检测患者血浆D-二聚体水平,110例行MRI检查。结果,59例(42%)D-二聚体水平升高,36例f61%)高于1.0mg/mL。6例纤维蛋白原水平降低。单因素分析显示。表面积大、静脉石及病变位于躯干者具有较高的血浆D-二聚体水平。多因素分析显示,表面积大及静脉石是与高水平D-二聚体相关的独立因素,严重UH与四肢静脉畸形有关。结论:LIH与静脉畸形大小的关系具有统计学意义。 | Dompmartin A Acher A Thibon P 王延安 | 2008 | 中国口腔颌面外科杂志2008，6，5： | 6 |
| 2 | Transperineal prostate biopsies for diagnosis of prostate cancer are well tolerated: a prospective study using patient-reported outcome measures显示文摘我们试图在有一般麻药 transperineal (TP ) 的男人决定短期的报导病人的结果前列腺活体检视。未来的队研究在有诊断 TP 活体检视的男人被执行。这用立即活体检视以后的一张验证并且适应的问询表并且在后续被做在越过三个第三级的工作分派的 7 和 14 天之间,有回答的医院 51.6% 评价。立即,在活体检视以后,人的 43/201 (21.4%) 感觉到头昏眼花, syncopal,或承受中略。百分之 53 个人在活体检视以后感到了不快(与 95% 得分 < 5 在 0-10 规模) 。12 在过程以后立即从 196 个人(6.1%) 感到了疼痛。尽管有症状的高发生(例如直到 75% 有的一些血尿症, 47% 得了一些疼痛) ,它不是为大多数的一个中等或严重的问题,除了 31 个人承受了的 hemoejaculate。十一个人需要 catheterization (5.5%) 。由于复杂并发症没有住院病人录取(血尿症,败血) 。在重复在一个以后的时间点询问以后,仅仅人的 25/199 (12.6%) 说尽管有重要、显著的减小,重复活体检视将是一个重要问题。从这研究,我们断定那 TP 活体检视很好与类似的副作用侧面和人的态度被容忍重复活体检视到有 TRUS 活体检视的人。这些数据给予与局部麻醉 TP 活体检视为 tolerability 在 TP 活体检视和一个基准以前人建议通知为临床的使用正在被开发。 | Karan Wadhwa Lina Carmona-Echeveria Timur Kuru Gabriele Gaziev Eva Serrao Deepak Parasha Julia Frey Ivailo Dimov Jonas Seidenader Pete Acher Gordon Muir Andrew Doble Vincent Gnanapragasam Boris Hadaschik Christof Kastner | 2017 | Asian Journal of Andrology2017，19，1： | 5 |
| 3 | VSITA, an Improved Approach of Target Amplification in the Identification of Viral Pathogens显示文摘Objective Unbiased next generation sequencing(NGS) is susceptible to interference from host or environmental sequences. Consequently, background depletion and virome enrichment techniques are usually needed for clinical samples where viral load is much lower than background sequences. Methods A viral Sequence Independent Targeted Amplification(VSITA) approach using a set of non-ribosomal and virus-enriched octamers(V8) was developed and compared with traditionally used random hexamers(N6). Forty-five archived clinical samples of different types were used in parallel to compare the V8 and N6 enrichment performance of viral sequences and removal performance of ribosomal sequences in the step of reverse transcription followed by quantitative PCR(qP CR). Ten sera samples from patients with fever of unknown origin and 10 feces samples from patients with diarrhea of unknown origin were used in comparison of V8 and N6 enrichment performance following NGS analysis. Results A minimum 30 hexamers matching to viral reference sequences(sense and antisense) were selected from a dataset of random 4,096(4~6) hexamers(N6). Two random nucleotides were added to the 5' end of the selected hexamers, and 480(30 × 4~2) octamers(V8) were obtained. In general, VSITA approach showed higher enrichment of virus-targeted c DNA and enhanced ability to remove unwanted ribosomal sequences in the majorities of 45 predefined clinical samples. Moreover, VSITA combined with NGS enabled to detect not only more viruses but also achieve more viral reads hit and higher viral genome coverage in 20 clinical samples with diarrhea or fever of unknown origin. Conclusion The VSITA approach designed in this study is demonstrated to possess higher sensitivity and broader genome coverage than traditionally used random hexamers in the NGS-based identification of viral pathogens directly from clinical samples. | ZHANG Yi ZHANG Chen LI Bo LI Yang HE Xiao Zhou LI Acher WU Wei DUAN Su Xia QIU Fang Zhou WANG Ji SHEN Xin Xin YANG Meng Jie LI De Xin MA Xue Jun | 2018 | Biomedical and Environmental Sciences2018，31，4： | 3 |
| 4 | Photodecomposition of Propachlor显示文摘 | Rejto M Saltzman S Acher A J | 1984 | Journal of Agricultural and Food Chemistry1984，32，2： | 1 |
| 5 | Redefining the limits of flexible ureterorenoscopy 显示文摘 | Hussain M Acher P Penev B | 2011 | J Endourol2011，25，： | 1 |
| 6 | Redefining the limits of fle-xible ureterorenoscopy显示文摘 | Hussain M Acher P Penev B | | 0，，01： | 1 |
| 7 | Impact of intraoperative ar- teriograp-hy on limb salvage for traumatic popliteal artery injury 显示文摘 | Callcut RA Acher CW Hoch J | 2009 | J Trauma2009，67，2： | 1 |
| 8 | Indications,results and safetyprofile of transperineal sector biopsies (TPSB) of the prostate:asingle centre experience of 634 cases显示文摘 | Vyas L Acher P Kinsella J | 2014 | BJU Int2014，114，1： | 1 |
| 9 | 显示文摘 | Acher O Jacquart P M Fontaine J M | 1994 | IEEE Trans Magn1994，30，6： | 1 |
| 10 | 显示文摘 | Toneguzzo Ph Acher O | 1997 | J Appl Phys1997，81，8： | 1 |
| 11 | Redefining the limits of flexible ureterorenoscopy 显示文摘 | HUSSAIN M ACHER P PENEV B | 2011 | J Endourol2011，25，1： | 1 |
| 12 | Preparation and microwave characterization of spherical and monodisperse CoNi particles显示文摘 | RAVEL F ACHER P | 1994 | Appl Phys1994，，10： | 1 |
| 13 | Dye-sensitized-photo-oxidation:A new approach to the treatment of organic matter in sewage effluents显示文摘 | Acher A J Rosenthal I | 2000 | Water Research2000，11，2： | 1 |
| 14 | Effect of Echistatin and RGD peptide on orthodontic tooth movement显示文摘 | Dloce C Vakani A Acher L | 2003 | J Dent Res2003，82，9： | 1 |
| 15 | Investigation of high frequency permeability of thin amorphous wires 显示文摘 | Acher O Jacquart P M Boscher C | 1994 | IEEE Trans Magn1994，30，6： | 1 |
| 16 | 显示文摘 | Acher O Jacquart P M Boscher C | 1994 | IEEE Trans Magn1994，30，6： | 1 |
| 17 | Chloroplast and mitochondrial molecular tests identify European×Japanese larch hybrids显示文摘 | V. Acheré P. Faivre Rampant L. E. Paques D. Prat | 2004 | Theoretical and Applied Genetics2004，，8： | 1 |
| 18 | 显示文摘 | Acher O Baclet P Perrin G | 1996 | J Magn Magn Mater1996，157，158： | 1 |
| 19 | 显示文摘 | Acher O Pierrin O | 1996 | IEEE Trans Microwave Theory Tech1996，44，5： | 1 |
| 20 | Preparation and microwave characterization of spherical and monodisperse Co-Ni particles 显示文摘 | Viau G Ravel F Acher O Fievet-Vincent F Fievet F | 1995 | Journal of Magnetism and Magnetic Materials1995，140，144： | 1 |
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