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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Guidelines for percutaneous coronary interventions.The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology显示文摘 | Silber S Albertsson P Aviles FF | | 0，，： | 2 |
| 3 | For the Task Force for Percutaneous Coronary interventions of the European Society of Cardiology: Guidelines for percutaneous coronary interventions 显示文摘 | SILBER S ALBERTSSON P AVILES FF | 2005 | Eur Heart J2005，26，： | 1 |
| 4 | The task force for percutaneous coronary interventions of the European Society of Cardiology显示文摘 | Silber S Albertsson P Aviles FF | 2005 | Eur Heart J2005，26，6： | 1 |
| 5 | Imnmnotactoid glomerulopathy in sickle cell anemia 显示文摘 | Aviles D H Craver R Warrier R P | 2001 | Pediatr Nephrol2001，16，1： | 1 |
| 6 | Conformal deformations of complete manifolds with negative curvature 显示文摘 | AVILES P MCOWEN R | 1985 | J Diff Geom1985，21，： | 1 |
| 7 | Guidelines for percutaneous coronary interventions显示文摘 | Albertsson P Aviles FF | 2005 | Eur Heart J2005，26，8： | 1 |
| 8 | Guidelines for percutaneous coronary interventions显示文摘 | Silber S Albertsson P Aviles FF | 2005 | European Heart Journal2005，26，： | 1 |
| 9 | Markers of airway remodeling ininducedsputum from healthy smokers 显示文摘 | Avils B’Belda J Margarit G Bellido-Casado J Martlnez-Bni C Casan P | 2006 | ArchBronconeumol2006，42，5： | 1 |
| 10 | Guidelines for Percutaneous coronary intervention显示文摘 | Albertsson P Aviles FF | 2005 | Eur Heart J2005，26，8： | 1 |
| 11 | Guidelines for percuta neous coronary interventions The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology显示文摘 | Silber S Albertsson P Avils FF | 2005 | Eur Heart J2005，26，8： | 1 |
| 12 | Guidelines for pereutaneous coronary interventions:the task force for percutaneous coronary interventions of the European Society of Cardiology显示文摘 | Silber S Albertsson P Avilés FF | | 0，，08： | 1 |
| 13 | Thermal study of the effect of several solvents on polymerization of acrylonitrile and their subsequent pyrolysis显示文摘 | Sanchez-Soto P J Aviles M A del Rio J C | 2001 | Journal of analytical and applied pyrolysis2001，5859，： | 1 |
| 14 | Use- fulness of b-trace protein and cystatin C for the pre- diction of mortality in non ST segment elevation acute coronary syndromes显示文摘 | Manzano-Ferna'ndez S Lo'pez-Cuenca A Januzzi JL Par- ra- Pallares S Mateo-Martl'nez A Sa'nchez-Martl'nez M Pe'rez Berbel P Orenes-Pinero E Romero-Aniorte AI Avile's Plaza F Valde's-Chavarri M Marl'n F | 2012 | AmJ Cardiol2012，110，12： | 1 |
| 15 | Automated structure based prediction of functional sites in proteins: applications to assessing the validity of inheriting protein function from homology in genome annotation and to protein docking 显示文摘 | Aloy P Querol E Aviles FX | 2001 | Mol Biol2001，311，2： | 1 |
| 16 | Guidelines for percutaneous coronary interventions:the task force for percutaneous coronary interventions of the European Society of Cardiology显示文摘 | Silber S Albertsson P Aviles FF | 2005 | Eur Heart J2005，26，8： | 1 |
| 17 | Guidelines for percutaneous coronary interventions: The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology 显示文摘 | Silber S Albertsson P Aviles FF | 2005 | Eur Heart J2005，26，8： | 1 |
| 18 | Guidelines for percutaneous coronary interventions显示文摘 | Silber S Albertsson P Aviles FF | 2005 | Rev Esp Cardiol2005，58，6： | 1 |
| 19 | Induction of broad cytotoxic T cells by protective DNA vaccination against marburg and ebola显示文摘 | Shedlock D J Avile J Talbott K T Wong G Wu S J Villarreal D O Myles D J Croyle M A Yan J Kobinger G P Weiner D B | 2013 | Mol Ther2013，21，7： | 1 |
| 20 | Validation of a sensitive assay for thiocoraline in mouse plasma using liquid chromatography-tandem mass spectrometry 显示文摘 | Yin JM Aviles P Leea W | 2003 | oJournal f Chromatography B2003，794，： | 1 |
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