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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | The cesarean delivery scar pouch:clinical implications and diagnostic correlation between transvaginal sonography and hysteroscopy显示文摘 | Fabres C Aviles G De La Jara C | | 0，，07： | 1 |
| 3 | Surveillance of methicillin - resistant Staphylococcus aureus in a pediatric hospital in Mexico City during a 7 - year period ( 1997 to 2003) : clonal evolution and impact of infection control显示文摘 | Velazquez - Meza ME Aires de Sousa M Echaniz - Aviles G | 2004 | J Clin Microbiol2004，42，8： | 1 |
| 4 | The cesarean delivery scar pouch:clinical implications and diagnostic correlation between transvaginal sonography and hysteroscopy显示文摘 | Fabres C Aviles G De La Jara C | 2003 | J Ultrasound Med2003，22，7： | 1 |
| 5 | Scaling differences between large interpolate and intraplate earthquakes显示文摘 | Scholz C H Aviles C A Wesnousky S G | 1986 | Bull Seismol Soe Am1986，76，1： | 1 |
| 6 | The cesarean delivery scar pouch: clinical implications and diagnostic correlation between transvaginal sonography and hysteroscopy 显示文摘 | Fabres C Aviles G De La lara C | 2003 | JUltrasound Med2003，22，： | 1 |
| 7 | Markers of airway remodeling ininducedsputum from healthy smokers 显示文摘 | Avils B’Belda J Margarit G Bellido-Casado J Martlnez-Bni C Casan P | 2006 | ArchBronconeumol2006，42，5： | 1 |
| 8 | Transmission of western equine encephalomyelitis virus by argentine Aedes albifasciatus ( Diptera: Culicidae) 显示文摘 | Aviles G Sabattini MS Mitchell CJ | 1992 | J Med Entomol1992，29，5： | 1 |
| 9 | The cesarean delivery scar pouch: clinical implications and diagnostic correlation between transvaginal sonography and hysteros- copy显示文摘 | Fabres C Aviles G De La Jara C | 2003 | J Ultrasound Med2003，22，7： | 1 |
| 10 | Phylogenetie relationships of dengue-1 viruses from argentina and paraguay显示文摘 | AVILES G ROWE J MEISSNER J | 2002 | Arch Virol2002，147，11： | 1 |
| 11 | The conformation of histone h5 显示文摘 | AVILES Francisco J CHAPMAN George E KNEALE Geoff G | 1978 | Europe- an Journal of Biochemistry1978，88，2： | 1 |
| 12 | Markers of airway remodeling in induced sputum from healthy smokers 显示文摘 | Aviles B Belda J Margarit G | 2006 | Arch Bronconeumol2006，42，5： | 1 |
| 13 | The cesarean delivery scar pouch: clinical implications and diagnostic correlation between transvaginal sonography and hysteroscopy 显示文摘 | Fabres C Aviles G De La Jara C | 2003 | J Ultrasound Med2003，22，7： | 1 |
| 14 | The cesarean deliv- ery scar pouch clinical implications and diagnostic correlation between transvaginal sonography and hysteroseopy显示文摘 | Fabres C Aviles G De La Jara C | 2003 | J Ul- trasound Med2003，22，7： | 1 |
| 15 | The cesarean delivery scar pouch: clinical implications and diagnostic correlation between transvaginal sonography and hysteroscopy 显示文摘 | Fabres C Aviles G De La Jara C | 2003 | J Ultrasound Med2003，22，7： | 1 |
| 16 | Induction of broad cytotoxic T cells by protective DNA vaccination against marburg and ebola显示文摘 | Shedlock D J Avile J Talbott K T Wong G Wu S J Villarreal D O Myles D J Croyle M A Yan J Kobinger G P Weiner D B | 2013 | Mol Ther2013，21，7： | 1 |
| 17 | The cesarean delivery scarpouch : clinical implications and diagnostic correlation between trans-vaginai sonography and hysteroscopy 显示文摘 | Fabres C Aviles G De La Jara C | 2003 | J Ultrasound Med2003，22，7： | 1 |
| 18 | Phylogenetic relationships of dengue -1 viruses from Argentina and Paraguay显示文摘 | Aviles G Rowe J Meissner J | 2002 | Arch Virol2002，147，20： | 1 |
| 19 | The cesarean delivery scar pouch: clinical implications and diagnostic correlation between transvaginal sonography and hysteroscopy显示文摘 | Fabres C Aviles G De La Jara C | 2003 | J Ultrasound Med2003，22，7： | 1 |
| 20 | Phylogenetic relationships of dengue-1 viruses from Argentina and Paraguay显示文摘 | Aviles G Rowe J Meissner J | 2002 | Arch Virol2002，147，11： | 1 |
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