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2篇 您的检索式:作者名="AUGE Jacques"
    题名 作者 年代 出处 被引量
1Synthesis of alkynes and alkynyl iodides bearing a protected amino alcohol moiety as functionalized amino acids precursors显示文摘Amino acid precursors in protected amino alcohol form are important synthons that can be used as building-blocks for the hemisynthesis of non-natural amino acids.Serine can be used as a common starting material for the synthesis of such compounds differently protected.Particularly,protected amino alcohols bearing an ethynyl and/or an iodoethynyl group can be used in cross-couplings,in 1,3-dipolar cycloadditions and/or in Nozaki-Hiyama-Kishi type reactions.We thus demonstrated that the efficiently protected amino alcohols derived from serine can be coupled to a sugar derivative by an indium mediated alkynylation reaction.The conditions of this coupling are compatible with such functionalized derivatives and allow envisaging an access to C-glycosylated amino acids.AYED Charfedinne PICARD Julien LUBIN-GERMAIN Nadège UZIEL Jacques AUGE Jacques 2010Science China Chemistry2010,53,9:1
2Water promoted organic reaction显示文摘 Augé Jacques Queneau Yves 1994Synthesis1994,8,:1
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