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| 1 | Identification, synthesis and characterization of process related impurities of benidipine hydrochloride, stress-testing/stability studies and HPLC/UPLC method validations显示文摘Benidipine hydrochloride, used as an antihypertensive agent and long-acting calcium antagonist, is synthesized for commercial use as a drug substance in highly pure form. During the synthetic process development studies of benidipine, process related impurities were detected. These impurities were identi fi ed, synthesized and characterized and mechanisms of their formation were discussed in detail.After all standardization procedures, they were used as reference standards for analytical studies. In addition, a separate HPLC method was developed and validated for detection of residual 1-benzylpiperidin-3-ol(Ben-2), which is used during benidipine synthesis and controlled as a potential process related impurity. As complementary of this work, stress-testing studies of benidipine were carried out under speci fi ed conditions and a stability-indicating UPLC assay method was developed, validated and used during stability studies of benidipine. | Esen Bellur Atici Bekir Karl??a | 2015 | Journal of Pharmaceutical Analysis2015，5，4： | 2 |
| 2 | Modeling with Fractional Equations 显示文摘 | Atici F M Sengul S | 2010 | J Math Anal Appl2010，369，： | 1 |
| 3 | Assessment of ovarian reserve 显示文摘 | Bukulmez O and Atici A | 2004 | Curr Opin Obstet Gynecol2004，16，3： | 1 |
| 4 | On the existence of positive solutions for nonlinear differential equations with periodic boundary conditions显示文摘 | ATICI F M GUSEINOV G S | 2001 | Journal of Computational and Applied Mathematics2001，132，2： | 1 |
| 5 | Two-point boundary value problems for finite fractional difference equations 显示文摘 | Atici F M Eloe P W | 2011 | J Difference Equ Appl2011，17，4： | 1 |
| 6 | Cisplatin-based chemotherapy in elderly patients with advanced stage ( III B and IV ) non-small cell lung cancer patients显示文摘 | Ozkaya S Findik S Atici AG | 2011 | Neoplasma2011，58，4： | 1 |
| 7 | Hormonal and henry namic changes during percutaneous nephrolithotomy显示文摘 | Atici S Zeren S Aribogan A | 2001 | Int Urol Nephrol2001，32，3： | 1 |
| 8 | Accuracy of anatomical references used for rotational alignment of tibial component in total knee arthroplasty 显示文摘 | Sahin N Atici T Ozturk A | 2012 | Knee Surg Sports Traumatol Arthrosc2012，20，3： | 1 |
| 9 | Intestinal ischemia-reperfusion impairs liver regeneration after partial hepatectomy in rats显示文摘 | Atici AE Kaya Y Coskun T | 2003 | Hepatogastroenterology2003，50，51： | 1 |
| 10 | Evaluation of shoulder balance through growing rod intervention for early- onset scoliosis显示文摘 | Uzumcugil O Atici Y Ozturkmen Y Yalcinkaya M | 2011 | J Spinal Disord Tech2011，11，： | 1 |
| 11 | Initial value problems in discrete fractional calculus显示文摘 | ATICI F M ELOE P W | 2009 | Pro Amer Math-Soc2009，137，2： | 1 |
| 12 | A transform method in discrete fractional calculus 显示文摘 | ATICI F M ELOE P W | 2007 | lnt J Differ Eqs2007，2，2： | 1 |
| 13 | Carbon Emissions, Trade Liberalization, and the Japau-A SEAN Interaction: A Group-wise Examination显示文摘 | Atici C | 2012 | Journal of the Japanese and International Economies2012，26，4： | 1 |
| 14 | Mutation analysis in the fibroblast growth factor 14 gene: frameshift mutation and polymorphisms in patients with inherited ataxias显示文摘 | Dalski A Atici J Kreuz FR | 2005 | Europ J Hum Genet2005，13，： | 1 |
| 15 | Initial value problems in discrete fractional calculus 显示文摘 | ATICI F M ELOE P W | 2009 | Proc Amer Math Soc2009，，： | 1 |
| 16 | The effect of preventive use of alanyl-glutamine on diaphragm muscle function in cecal ligation and puncture-induced sepsis model显示文摘 | Doruk N Buyukakilli B Atici S | 2005 | JPEN J Parenter Enteral Nutr2005，29，1： | 1 |
| 17 | Two-point boundary value problems for finite fractional difference equations 显示文摘 | ATICI F M ELOE P W | 2011 | J Differ Eqs Appl2011，17，4： | 1 |
| 18 | The effect of tumor necrosis factor-α inhibitor soon after hypoxia-ischemia on heart in neonatal rats显示文摘 | Büyükakilli B Atici A zkan A | | 0，，21： | 1 |
| 19 | C-reactive protein values and erythrocyte sedimentation rates after total hip and total knee arthroplasty显示文摘 | Bilgen O Atici T Durak K | 2001 | J Int Med Res2001，29，1： | 1 |
| 20 | Wear characteristics of circular diamond saws in the cutting of different hard and abrasive rocks 显示文摘 | ERSOY A BUYUKSAGIS IS ATICI U | 2005 | Wear2005，258，： | 1 |
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