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| 1 | Electrocardiographic markers of cardiac resynchronization therapy response:delayed time to intrinsicoid deflection onset in lateral leads显示文摘Cardiac resynchronization therapy(CRT)has emerged as an important intervention for patients with heart failure(HF)with reduced ejection fraction and delayed ventricular activation.In these patients,CRT has demonstrated to improve quality of life,promote reverse left ventricular(LV)remodeling,reduce HF hospitalizations,and extend survival.However,despite advancements in our understanding of CRT,a significant number of patients do not respond to this therapy.Several invasive and non-invasive parameters have been assessed to predict response to CRT,but the electrocardiogram(ECG)has remained as the prevailing screening method albeit with limitations.Ideally,an accurate,simple,and reproducible ECG marker or set of markers would dramatically overcome the current limitations.We describe the clinical utility of an old ECG parameter that can estimate ventricular activation delay:the onset to intrinsicoid deflection(ID).Based on the concept of direct measurement of ventricular activation time(intrinsic deflection onset),time to ID onset measures on the surface ECG the time that the electrical activation time takes to reach the area subtended by the corresponding surface ECG lead.Based on this principle,the time to ID on the lateral leads can estimate the delay activation to the lateral LV wall and can be used as a predictor for CRT response,particularly in patients with non-specific intraventricular conduction delay or in patients with left bundle branch block and QRS<150 ms.The aim of this review is to present the current evidence and potential use of this ECG parameter to estimate LV activation and predict CRT response. | Rubén KA Tapia-Orihuela S Michael Gharacholou Samuel J Asirvatham Freddy Del-Carpio Munoz | 2022 | Journal of Geriatric Cardiology2022，19，1： | 3 |
| 2 | Clinical Presentation, Investigation, and Management of Pulmonary Vein Stenosis Complicating Ablation for Atrial Fibrillation显示文摘 | Douglas L. Packer Paul Keelan Thomas M. Munger Jerome F. Breen Sam Asirvatham Laura A. Peterson Kristi H. Monahan Mary F. Hauser K Chandrasekaran Lawrence J. Sinak David R. Holmes | 2005 | Circulation2005，，5： | 2 |
| 3 | Comparative outcomes of subcutaneous and transvenous cardioverter-defibrillators显示文摘Background: The comparative outcomes of subcutaneous implantable cardioverter-defibrillator (S-ICD) and transvenous (T-ICD) have not been well studied. The aim of this study was to evaluate the safety and efficacy of currently available S-ICD and T-ICD. Methods: The study included 86 patients who received an S-ICD and 1:1 matched to those who received single-chamber T-ICD by gender, age, diagnosis, left ventricular ejection fraction (LVEF), and implant year. The clinical outcomes and implant complications were compared between the two groups. Results: The mean age of the 172 patients was 45 years, and 129 (75%) were male. The most common cardiac condition was hypertrophic cardiomyopathy (HCM, 37.8%). The mean LVEF was 50%. At a mean follow-up of 23 months, the appropriate and inappropriate ICD therapy rate were 1.2% vs. 4.7%(X^2= 1.854, P=0.368) and 9.3% vs. 3.5%(X^2 = 2.428, P = 0.211) in S-ICD and T-ICD groups respectively. There were no significant differences in device-related major and minor complications between the two groups (7.0% vs. 3.5%, X^2 = 1.055, P = 0.496). The S-ICD group had higher T-wave oversensing than T-ICD group (9.3% vs. 0%, X^2 = 8.390, P=0.007). Sixty-five patients had HCM (32 in S-ICD and 33 in T-ICD). The incidence of major complications was not significantly different between the two groups. Conclusions: The efficacy of an S-ICD is comparable to that of T-ICD, especially in a dominantly HCM patient population. The S-ICD is assodated with fewer major complications demanding reoperation. | Jin-Jun Liang Hideo Okamura Roshini Asirvatham Andrew Schneider David O. Hodge Mei Yang Xu-Ping Li Ming-Yan Dai Ying Tian Pei Zhang Bryan C. Cannon Cong-Xin Huang Paul A. Friedman Yong-Mei Cha | 2019 | Chinese Medical Journal2019，，6： | 2 |
| 4 | Puhnonary vein-related maneuvers:part Ⅰ 显示文摘 | Asirvatham SJ | 2007 | Heart Rhythm2007，4，4： | 1 |
| 5 | Premature ventricular contractions and non-sustained ventricular tachycardia: association with sudden cardiac death, risk stratification, and management strategies 显示文摘 | Sheldon SH Gard JJ Asirvatham S J | 2010 | Indian Pacing Electrophysiol J2010，10，8： | 1 |
| 6 | Mapping the Proteome of Barrel Medic (Medicago truncatula)显示文摘 | Watson B S Asirvatham V S Wang L J | 2003 | Plant Physiology2003，131，： | 1 |
| 7 | Teaching rounds in cardiac elee-trophysiology显示文摘 | Stevenson WG Asirvatham SJ | 2010 | Cire Arrhythm Electrophysiol2010，3，6： | 1 |
| 8 | The fourth dimension: endoeavitary ventrieular tachyeardia显示文摘 | Madhavan M Asirvatham SJ | 2010 | Circ Arrhythm Eleetrophysiol2010，3，： | 1 |
| 9 | Terrain rendering using GPU-based geometry Clipmaps显示文摘 | Asirvatham A Hoppe H | 2005 | GPU gems2005，2，2： | 1 |
| 10 | MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components显示文摘 | Asirvatham AJ Gregorie CJ Hu Z | 2008 | Mol Immunol2008，45，7： | 1 |
| 11 | Pediatric tumors of the central nervous system: a retrospective study of 1,043 cases from a tertiary care center in South India 显示文摘 | Asirvatham JR Deepti AN Chyne R | 2011 | Childs Nerv Syst2011，27，8： | 1 |
| 12 | Proximal tibial extension medial rotation osteotomy to correct knee flexion contracture and lateral rotation deformity of tibia after polio显示文摘 | Asirvatham R Rooney RJ Watts HG | 1991 | J Pediatr Orthop1991，11，： | 1 |
| 13 | Success of ablation for atrial fibrillation in isolated left ventricular diastolic dysfunction: a comparison to systolic dysfunction and normal ventricular function显示文摘 | Cha YM Wokhlu A Asirvatham SJ etal | 2011 | Circ Arrhythm Electrophysiol2011，4，5： | 1 |
| 14 | Upgrade and de novo cardiac resynchronization therapy:impact of paced or intrinsic QRS morphology on outcomes and survival显示文摘 | Wokhlu A Rea RF Asirvatham SJ | 2009 | Heart Rhythm2009，6，10： | 1 |
| 15 | miRNA regulation of cytokine genes显示文摘 | Asirvatham A J Magner WJ Tomasi TB | 2009 | Cytokine2009，45，： | 1 |
| 16 | Left atrial appendage as a target for reducing strokes :justifiable rationale? Safe and effec- tive approaches? 显示文摘 | Syed FF Asirvatham SJ | 2011 | Heart Rhythm2011，8，2： | 1 |
| 17 | Clinical Presentation, Investigation, and Management of Pulmonary Vein Stenosis Complicating Ablation for Atrial Fibrillation显示文摘 | Douglas L. Packer Paul Keelan Thomas M. Munger Jerome F. Breen Sam Asirvatham Laura A. Peterson Kristi H. Monahan Mary F. Hauser K Chandrasekaran Lawrence J. Sinak David R. Holmes | 2005 | Circulation2005，，5： | 1 |
| 18 | Premature ventricular contractions and non-sustained ventricular tachycardia: association with sudden cardiac death, risk stratification, and management strategies 显示文摘 | Sheldon S H Gard J J Asirvatham S J | 2010 | Indian Pacing Electrophysiol J2010，10，8： | 1 |
| 19 | Noncontact mapping to guide ablation of fight ventricular outflow tract tachycardia显示文摘 | Friedman PA Asirvatham S J Grice S | 2002 | J Am Coll Cardiol2002，39，11： | 1 |
| 20 | The presence of ventricular muscular extensions into the pulmonary artery and aorta beyond the semilunar valves显示文摘 | Asirvatham SJ Friedman PA Packer DL | 2001 | PACE2001，24，： | 1 |
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