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| 1 | B lymphocytes regulate airway granulocytic inflammation and cytokine production in a murine model of fungal allergic asthma显示文摘到真菌的促进感受性经常导致是特别地困难的临床上设法的气喘的一种严重形式,导致在这些病人的增加的病态和住院。尽管 B 淋巴细胞可能通过 IgE 的生产加重气喘症状,这些房间可能也在对吸入的真菌的保护的反应是重要的。通过 cytokine 版本和 T 房间相互作用,这些淋巴细胞可能也影响航线墙纤维变性的发展和维护。J H −/− 老鼠为抗体的重链部件缺乏 JH 基因,它为 B 房间功能和幸存是批评的。这些动物在很多有免疫力的回答便于 B 淋巴细胞的角色的说明;然而, J H −/− 老鼠没被用来学习真菌的过敏症。在这研究,我们用曲霉属菌 fumigatus 检验了 B 淋巴细胞的角色模仿被环境真菌的暴露触发的人的航线疾病的鼠科的真菌的高空过敏症模型。我们在敏化的野类型的 BALB/c 和 J 暴露于的 H −/− 老鼠重复了真菌的暴露并且没在大航线附近在航线 hyperresponsiveness,全面肺的发炎或骨胶原免职发现差别。然而, Th2 类型 cytokines IL-4 和 IL-13 的层次显著地在 J 相对 BALB/c 控制的 H −/− 鼠标。由对比,煽动性的 cytokines IL-17A 和 IL-6 的层次显著地在 J H −/− 动物,并且有显著地更柔韧的航线嗜曙红血球过多和 neutrophilia 比在控制动物。一起拿,这些调查结果表明淋巴细胞帮助在肺的分隔空间调整 granulocytic 回答到真菌的暴露的那 B。 | Sumit Ghosh Scott A Hoselton Scott V Asbach Breanne N Steffan Steve B Wanjara Glenn P Dorsam Jane M Schuh | 2015 | Cellular & Molecular Immunology2015，12，2： | 2 |
| 2 | A prospective study for comparison of MR and CT imaging for detection of coronary artery stenosis 显示文摘 | Hamdan A Asbach P WeUnhofer E | 2011 | Journal of JACC Cardiovascular Imaging2011，4，1： | 1 |
| 3 | Viscoelasticity-based staging of hepatic fibrosis with muhifrequency MR elastogra- phy 显示文摘 | Asbach P Klatt D Schlosser B | 2010 | Radiology2010，257，1： | 1 |
| 4 | Statin- associated focal myositis显示文摘 | Asbach P Paetsch I Stawowy P | 2009 | Int J Cardiol2009，133，： | 1 |
| 5 | Magnetic resonance cholangiopancreatography using a free-breathing T2 -weightoA turbo spin -echo sequence with navigator-triggered prospective acquisition correction显示文摘 | Klessen C Kroencke TJ | 2005 | Mngn Reson Imaging2005，23，9： | 1 |
| 6 | Ultrasound-based navigation and 3D CT compared in acetabular cup position显示文摘 | Hasart O Poepplau BM Asbach P | | 0，，10： | 1 |
| 7 | Magnetic resonance imaging findings of atypical focal nodular hyperplasia of the liver显示文摘 | Asbach P Klessen C Koch M | 2007 | Clinical Imaging2007，31，4： | 1 |
| 8 | The ependymal 'Dot-Dash' sign: an MR imaging finding of early multiple sclerosis显示文摘 | Lisanti C J Asbach P Bradley WG | 2005 | AJNR Am J Neuroradiol2005，26，8： | 1 |
| 9 | The epen- dymal 'Dot Dash' sign= An MR imaging finding of early mul tiple sclerosis显示文摘 | LISANTI C J ASBACH P BRADLEY WG J R | 2005 | Am J Neuroradiol2005，26，8： | 1 |
| 10 | In vivo determination of hepatic stiffness using steady-state free precession magnetic resonance elastography显示文摘 | Klatt D Asbach P Rump J | 2006 | Invest Radiol2006，41，： | 1 |
| 11 | Brk/Protein tyrosine ki- nase 6 phosphorylates p27KIP1, regulating the activity of Cyclin D - Cyclin - dependent kinase 4 显示文摘 | Patel P Asbach B Shteyn E | 2015 | Mol Cell Biol2015，35，9： | 1 |
| 12 | Behavior of metal implants used in ENT surgery in 7 Tesla magnetic resonance imaging显示文摘 | Thelen A Bauknecht HC Asbach P | 2006 | Eur Arch Otorhinolaryngol2006，263，： | 1 |
| 13 | Magnetic resonance imaging of the upper abdomen using a free-breathing T2-weighted turbo spin echo sequence with navigator triggered prospective acquisition correction 显示文摘 | Klessen Cv Asbach P Kroencke TJ | 2005 | J Magn Reson Imaging2005，21，5： | 1 |
| 14 | Free-breathing echo-planar imaging based diffusion-weighted magnetic resonance imaging of the liver with prospective acquisition correction显示文摘 | Asbach P Hein PA Stemmer A | 2008 | JCAT2008，32，： | 1 |
| 15 | Magnetic resonance cholangiopancreatography using a free-breathing T2-weighted turbo spin-echo sequence with navigator-triggered prospective acquisition correction显示文摘 | Asbach P Klessen C Kroencke T J | 2005 | Magn Reson Imaging2005，23，9： | 1 |
| 16 | Viscoelasticity-based stag- ing of hepatic fibrosis with muhifrequency MR elastography显示文摘 | Asbach P Klatt D Schlosser B | 2010 | Radiology2010，257，1： | 1 |
| 17 | In vivo determination of hepatic stiffness using steady-state free precession magnetic resonance elastography 显示文摘 | KLATT D ASBACH P RUMP J | 2006 | Invest Radiol2006，41，： | 1 |
| 18 | Ultrasound-based navigation and 3D CT compared in acetabular cup position显示文摘 | Hasart O Poepplau BM Asbach P | 2009 | Orthopedics2009，32，10： | 1 |
| 19 | Viscoelasticity-based staging of hepatic fibrosis with multifrequency MR elastography 显示文摘 | Asbach P Klatt D Schlosser B | 2010 | Radiology2010，257，1： | 1 |
| 20 | Magnetic resonance cholangiopancreatography using a free - breathing T2 - weighted turbo spin - echo sequence with navigator - triggered prospective acquisition correct 显示文摘 | Asbach P Klessen C Thomas J | 2005 | Magnetic resonance imaging2005，23，9： | 1 |
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