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| 1 | Analyzing predictors of graft survival in patients undergoing liver transplantation with donors aged 70 years and over显示文摘AIM To increase the number of available grafts.METHODS This is a single-center comparative analysis performed between April 1986 and May 2016. Two hundred and twelve liver transplantation(LT) were performed with donors ≥ 70 years old(study group). Then, we selected the first cases that were performed with donors < 70 years old immediately after the ones that were performed with donors ≥ 70 years old(control group).RESULTS Graft and patient survivals were similar between both groups without increasing the risk of complications, especially primary non-function, vascular complications and biliary complications. We identified 5 risk factors as independent predictors of graft survival: recipient hepatitis C virus(HCV)-positivity [hazard ratio(HR) = 2.35; 95% confidence interval(CI): 1.55-3.56; P = 0.00]; recipient age(HR = 1.04; 95%CI: 1.02-1.06; P = 0.00); donor age X model for end-stage liver disease(D-MELD)(HR = 1.00; 95%CI: 1.00-1.00; P = 0.00); donor value of serum glutamic-pyruvic transaminase(HR = 1.00; 95%CI: 1.00-1.00; P = 0.00); and donor value of serum sodium(HR = 0.96; 95%CI: 0.94-0.99; P = 0.00). After combining D-MELD and recipient age we obtained a new scoring system that we called DR-MELD(donor age X recipient age X MELD). Graft survival significantly decreased in patients with a DR-MELD score ≥ 75000, especially in HCV patients(77% vs 63% at 5 years in HCV-negative patients, P = 0.00; and 61% vs 25% at 5 years in HCV-positive patients; P = 0.00). CONCLUSION A DR-MELD ≥ 75000 must be avoided in order to obtain the best results in LT with donors ≥ 70 years old. | Oscar Caso-Maestro Carlos Jiménez-Romero Iago Justo-Alonso Jorge Calvo-Pulido David Lora-Pablos Alberto Marcacuzco-Quinto Félix Cambra-Molero Alvaro García-Sesma Marina Pérez-Flecha Carlos Munoz- Arce Carmelo Loinaz-Segurola Alejandro Manrique-Municio | 2018 | World Journal of Gastroenterology2018，24，47： | 2 |
| 2 | Human KLRFI, a novel member of the killer cell lectin-like receptor gene family: molecular characterization, genomic, structure, physical mapping to the NK gene complex and expression analysis 显示文摘 | Roda-Navarro P Arce I Renedo M | 2000 | Eur J Immunol2000，30，2： | 1 |
| 3 | Clinical outcome following stimulation with highly purified hMG or recombinant FSH in Patients undergoing IVF:a randomized assessor-blind controlled trial显示文摘 | Andersen AN Devroey P Arce JC | 2006 | Hum Reprod2006，21，12： | 1 |
| 4 | Molecular characterization of two novel alternative spliced variants of the KLRF1 gene and subcellular distribution of KLRF1 isoforms 显示文摘 | Roda-Navarro P Hemanz-Falcon P Arce I | 2001 | Biochim Biophys Acta2001，1520，2： | 1 |
| 5 | Formation of hydroxyl radicals,hydrogen peroxides and aqueous electrons by pulsed streamer corona discharge in aqueous solution显示文摘 | Joshi A A Locke B R Arce P | 1995 | J Hazardous Materials1995，41，1： | 1 |
| 6 | Weathering traces in ancient bricks from historic buildings 显示文摘 | Lopez Arce P Garcia Guinea J | 2005 | Building and Environment2005，40，： | 1 |
| 7 | Theoretical analysis of the MAX/Median filter显示文摘 | Arce G R McLoughlin M P | 1987 | IEEE Trans Acoust Speech Signal Processing1987，35，1： | 1 |
| 8 | Formation of hydroxyl radicals, hydrogen peroxide and aqueous electrons by pulsed streamer corona discharge in aqueous solution显示文摘 | Joshi A A Locke B R Arce P | 1995 | Journal of Hazardous Materials1995，41，1： | 1 |
| 9 | Determining corneal power using Orbscan Ⅱ videokeratography for IOL calculation after excimer laser surgery for myopia显示文摘 | Arce CG Campos M Schor P | | 0，，： | 1 |
| 10 | Effect of total ammonia nitrogen concentration and pH on growth rates of duckweed(Spirodela polyrrhiza) 显示文摘 | Caidedo J R N Steen P V D Arce O G ilzen H J | 2000 | Wat Res2000，34，15： | 1 |
| 11 | The potato transcriptional co-activator StMBF1 is up-regulated in response to oxidative stress and interacts with the TATA-box binding protein显示文摘 | ARCED P TONON C ZANETTI M E | 2006 | Journal of Biochemistry and Molecular Biology2006，39，4： | 1 |
| 12 | Clinical outcome following stimulation with highly purified hMG or recombinant FSH in patients undergoing IVF: a randomized assessor-blind controlled trial显示文摘 | Andersen A N Devroey P Arce J C | 2006 | Hum Reprod2006，21，12： | 1 |
| 13 | Formation of hydroxyl radicals,hydrogen peroxides and aqueous electrons by pulsed streamer corona discharge in aqueous solution显示文摘 | Joshi A A Locke B R Arce P | 1995 | J Hazardous Materials1995，41，1： | 1 |
| 14 | A preliminary study of pulsed streamer corona discharge for the degradation of MB in aqueous solution显示文摘 | Sharma A K Locke B R Arce P | 1993 | Hazardous Waste and Hazardous Materials1993，10，2： | 1 |
| 15 | Formation of hydroxyl radicals, hydrogen peroxide and aqueous electrons by pulsed streamer corona discharge in aqueous solution显示文摘 | JOSHI A A LOCKE B R ARCE P | 1995 | Journal of Hazardous Materials1995，41，1： | 1 |
| 16 | A preliminary study of pulsed streamer corona discharge for the degradation of phenol in aqueous solutions显示文摘 | SHARMA A K LOCKE B R ARCE P | 1993 | Hazardous Waste and Hazardous Materials1993，10，2： | 1 |
| 17 | Effect of total ammonia nitrogen concentration and pH on growth rates of duckweed (Spirodela polyrrhiza)显示文摘 | Caicedo J R Van der Steen N P Arce O | 2000 | Water Research2000，34，15： | 1 |
| 18 | Recognizing spinal cord emergencies 显示文摘 | ARCE D SASS P ABUL - KHOUDOUD H | 2001 | Am Faro Physician2001，64，4： | 1 |
| 19 | A preliminary study of pulsed streamer corona discharge for degration of phenol in aqueous solution 显示文摘 | Sharma A K Locke B R Arce P | 1993 | Hazardous waste & Hazardous material1993，10，2： | 1 |
| 20 | Effect of total ammonia nitrogen concentration and pH on growth rates of duckweed(Spirodela polyrrhiza) 显示文摘 | Caicedo J R van der Steen N P Arce O Gijzen H J | 2000 | Water Research2000，34，： | 1 |
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