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| 1 | Combining computer vision and deep learning to enable ultra-scale aerial phenotyping and precision agriculture:A case study of lettuce production显示文摘Aerial imagery is regularly used by crop researchers,growers and farmers to monitor crops during the growing season.To extract meaningful information from large-scale aerial images collected from the field,high-throughput phenotypic analysis solutions are required,which not only produce high-quality measures of key crop traits,but also support professionals to make prompt and reliable crop management decisions.Here,we report AirSurf,an automated and open-source analytic platform that combines modern computer vision,up-to-date machine learning,and modular software engineering in order to measure yield-related phenotypes from ultra-large aerial imagery.To quantify millions of in-field lettuces acquired by fixed-wing light aircrafts equipped with normalised difference vegetation index(NDVI)sensors,we customised AirSurf by combining computer vision algorithms and a deep-learning classifier trained with over 100,000 labelled lettuce signals.The tailored platform,AirSurf-Lettuce,is capable of scoring and categorising iceberg lettuces with high accuracy(>98%).Furthermore,novel analysis functions have been developed to map lettuce size distribution across the field,based on which associated global positioning system(GPS)tagged harvest regions have been identified to enable growers and farmers to conduct precision agricultural practises in order to improve the actual yield as well as crop marketability before the harvest. | Alan Bauer Aaron George Bostrom Joshua Ball Christopher Applegate Tao Cheng Stephen Laycock Sergio Moreno Rojas Jacob Kirwan Ji Zhou | 2019 | Horticulture Research2019，6，1： | 14 |
| 2 | 为学生营造舒适的学习共享空间——以美国印第安纳州普渡大学印第安纳波利斯分校图书馆为例显示文摘对印第安纳州普渡大学印第安纳波利斯分校(IUPUI)图书馆非计算机区和非图书馆区域的系统观察表明,图书馆在个人和小组学习区域选择中有重要作用,图书馆是学生首选的学习场所。研究表明,图书馆座位的设置、空间使用情况包括笔记本电脑的使用需求及性别偏好等都是图书馆设计应该考虑的重要问题。 | Rachel Applegate 姚玲杰 | 2010 | 图书馆建设2010，，3： | 8 |
| 3 | High-attenuation mucus plugs on MDCT in a child with cystic fibrosis: potential cause and differential diagnosis显示文摘 | Andrey Morozov Kimberly E. Applegate Shanaree Brown Michelle Howenstine | 2007 | Pediatric Radiology2007，，6： | 3 |
| 4 | Role of retinoids in the prevention and treatment of colorectal cancer显示文摘Vitamin A and its derivatives, retinoids, have been widely studied for their use as cancer chemotherapeutic agents. With respect to colorectal cancer(CRC), several critical mutations dysregulate pathways implicated in progression and metastasis, resulting in aberrant Wnt/β-catenin signaling, gain-of-function mutations in K-ras and phosphatidylinositol-3-kinase/Akt, cyclooxygenase-2 over-expression, reduction of peroxisome proliferatoractivated receptor γ activation, and loss of p53 function. Dysregulation leads to increased cellular proliferation and invasion and decreased cell-cell interaction and differentiation. Retinoids affect these pathways by various mechanisms, many involving retinoic acid receptors(RAR). RAR bind to all-trans-retinoic acid(ATRA) to induce the transcription of genes responsible for cellular differentiation. Although most research concerning the chemotherapeutic efficacy of retinoids focuses on the ability of ATRA to decrease cancer cell proliferation, increase differentiation, or promote apoptosis; as CRC progresses, RAR expression is often lost, rendering treatment of CRCs with ATRA ineffective. Our laboratory focuses on the ability of dietary vitamin A to decrease CRC cell proliferation and invasion via RAR-independent pathways. This review discusses our research and others concerning the ability of retinoids to ameliorate the defective signaling pathways listed above and decrease tumor cell proliferation and invasion through both RAR-dependent and RAR-independent mechanisms. | Catherine C Applegate Michelle A Lane | 2015 | World Journal of Gastrointestinal Oncology2015，7，10： | 2 |
| 5 | Is it the time to reconsider the choice of valves for cardiac surgery: mechanical or bioprosthetic?显示文摘Valvular heart disease is a pathologic processinvolving one or more of the four valves (aortic,pulmonary, mitral and tricuspid) of the heart typified bystenosis or regurgitation and leading to patient symp-toms. The most common causes are tissue degeneration,rheumatic fever and congenital heart diseases. Aorticvalve replacement (AVR) using either mechanical orbioprosthetic (tissue) valves via open-heart surgicalAVR (SAVR) is the most widely accepted standardtreatment. | Patricia M Applegate W. Douglas Boyd Richard L. Applegate, Ⅱ Hong Liu | 2017 | The Journal of Biomedical Research2017，31，5： | 2 |
| 6 | Hydrogen from natural gas:part I-autothermal reforming in an integrated fuel processor显示文摘 | LEE S H D APPLEGATE D V AHMED S | 2005 | Int J Hydrogen Energy2005，30，8： | 1 |
| 7 | When appendicitis is suspected in children显示文摘 | Sivit C J Siegel M J Applegate K E | 2001 | Radiographics2001，21，1： | 1 |
| 8 | Periacinar stellate shaped cells in rat pancreas- identification,isolation,and culture显示文摘 | Apte MV Haber PS Applegate TL | 1998 | Gut1998，43，： | 1 |
| 9 | Superior in-hospital and 30-day outcomes with abciximab versus eptifibatide:a contemporary analysis of 495 consecutive percutaneous coronary interventions显示文摘 | Deliargyris EN Upadhya B Applegate RJ | 2004 | J Invasive Cardiol2004，16，11： | 1 |
| 10 | Intussusception in children:imaging choices显示文摘 | Applegate KE | 2008 | Semin Roentgenol2008，43，： | 1 |
| 11 | Optics of aberroscopy and super vision显示文摘 | Applegate RA Thibos LN Hilmantel G | | 0，，： | 1 |
| 12 | Optimizing wetland restoration and management for avian communities using a mixed integer programming approach 显示文摘 | STRALBERG D APPLEGATE D L PHILLIPS S J | 2009 | Biological Conservation2009，142，： | 1 |
| 13 | Predicting crystalline lens fall caused by accommodation from changes in wavefront error显示文摘 | He L Applegate RA | 2011 | Cataraet Re- fract Surg2011，37，7： | 1 |
| 14 | Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: a meta-analysis of randomised controlled trials 显示文摘 | Pahor M Psaty BM Alderman MH Applegate WB Williamson JD Cavazzini C Furberg CD | 2000 | Lancet2000，356，9246： | 1 |
| 15 | Change in depression as aprecursor of cardiovascular events: SHEP Cooperative Research Group (systolic hypertensionin the elderly)显示文摘 | 2,Wasserthiel-Smoller S Applegate WB Berge K | 1996 | Arch Intern Med1996，156，5： | 1 |
| 16 | Standards for reporting the optical aberrations of eyes显示文摘 | Thibos LN Applegate RA Schwiegerling JT | 2002 | J Refract Surg2002，18，： | 1 |
| 17 | Incidence of coronary stent thrombosis based on academic research consortium definitions显示文摘 | Applegate RJ Sacfinty MT Little WC | 2008 | Am J Cardiol2008，102，6： | 1 |
| 18 | The role of plaque size and degree of stenosis in acute myocardial infarction显示文摘 | APPLEGATE R J | 1996 | Cardiol Clin1996，14，： | 1 |
| 19 | Exercise and detraining-effect on food intake,adiposity and lipogenesis in Osborne-Mendel rats made obese by a high fat diet显示文摘 | Applegate EA Upton DE Stern JS | 1984 | J Nutr1984，114，2： | 1 |
| 20 | Trends in vascular complications after diagnostic cardiac catheterization and percutaneous coronary intervention via the femoral artery, 1998 to 2007显示文摘 | Applegate R J Saerinty MT Kutcher MA | 2008 | JACC Cardiovase Interv2008，1，： | 1 |
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