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| 1 | Predictors of suboptimal bowel preparation in asymptomatic patients undergoing average-risk screening colonoscopy显示文摘AIM To identify risk factors for a suboptimal preparation among a population undergoing screening or surveillance colonoscopy.METHODS Retrospective review of the University of Michigan and Veteran's Administration(VA) Hospital records from 2009 to identify patients age 50 and older who underwent screening or surveillance procedure and had resection of polyps less than 1 cm in size and no more than 2 polyps. Patients with inflammatory bowel disease or a family history of colorectal cancer were excluded. Suboptimal procedures were defined as procedure preparations categorized as fair, poor or inadequate by the endoscopist. Multivariable logistic regression was used to identify predictors of suboptimal preparation.RESULTS Of 4427 colonoscopies reviewed, 2401 met our inclusion criteria and were analyzed. Of our population, 16% had a suboptimal preparation. African Americans were 70% more likely to have a suboptimal preparation(95%CI: 1.2-2.4). Univariable analysis revealed that narcotic and tricyclic antidepressants(TCA) use, diabetes, prep type, site(VA vs non-VA), and presence of a gastroenterology(GI) fellow were associated with suboptimal prep quality. In a multivariable model controlling for gender, age, ethnicity, procedure site and presence of a GI fellow, diabetes [odds ratio(OR) = 2.3; 95%CI: 1.6-3.2], TCA use(OR = 2.5; 95%CI: 1.3-4.9), narcotic use(OR = 1.7; 95%CI: 1.2-2.5) and Miralax-Gatorade prep vs 4L polyethylene glycol 3350(OR = 0.6; 95%CI: 0.4-0.9) were associated with a suboptimal prep quality. CONCLUSION Diabetes, narcotics use and TCA use were identified as predictors of poor preparation in screening colonoscopies while Miralax-Gatorade preps were associated with better bowel preparation. | Shail M Govani Eric E Elliott Stacy B Menees Stephanie L Judd Sameer D Saini Constantinos P Anastassiades Annette L Urganus Suzanna J Boyce Philip S Schoenfeld | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，17： | 7 |
| 2 | Exogenous cytokinin application to Actinidia chinensis var. deliciosa ‘Hayward’ fruit promotes fruit expansion through water uptake显示文摘Exogenous application of a cytokinin-like compound forchlorfenuron(CPPU)can promote fruit growth,although often at the expense of dry matter(DM),an important indicator of fruit quality.Actinidia chinensis var.deliciosa‘Hayward’fruit are very responsive to CPPU treatments,but the mechanism underlying the significant fruit weight increase and associated decrease in DM is unclear.In this study,we hypothesised that CPPU-enhanced growth increases fruit carbohydrate demand,but limited carbohydrate supply resulted in decreased fruit DM.During fruit development,CPPU effects on physical parameters,metabolites,osmotic pressure and transcriptional changes were assessed under conditions of both standard and a high carbohydrate supply.We showed that CPPU increased fruit fresh weight but the dramatic DM decrease was not carbohydrate limited.Enhanced glucose and fructose concentrations contributed to an increase in soluble carbohydrate osmotic pressure,which was correlated with increased water accumulation in CPPU-treated fruit and up-regulation of water channel aquaporin gene PIP2.4 at 49 days after anthesis.Transcipt analysis suggested that the molecular mechanism contributing to increased glucose and fructose concentrations was altered by carbohydrate supply.At standard carbohydrate supply,the early glucose increase in CPPU fruit was associated with reduced starch synthesis and increased starch degradation.When carbohydrate supply was high,the early glucose increase in CPPU fruit was associated with a general decrease in starch synthesis but up-regulation of vacuolar invertase and fructokinase genes.We conclude that CPPU affected fruit expansion by increasing the osmotically-driven water uptake and its effect was not carbohydrate supply-limited. | Simona Nardozza Helen L Boldingh Mark W Wohlers Andrew P Gleave Zhiwei Luo Guglielmo Costa Elspeth A MacRae Michael J Clearwater Annette C Richardson | 2017 | Horticulture Research2017，4，1： | 2 |
| 3 | Effects of particulate air pollution on blood pressure and heart rate in subjects with cardiovascular disease: a multicenter approach显示文摘 | Angela IM Kirsi LT Annette P | 2004 | Environ Health Perspect2004，112，： | 1 |
| 4 | Organochlorine exposure and risk of breast cancer显示文摘 | Annette P H Philippe G Torben J | 1998 | Lancet1998，352，： | 1 |
| 5 | IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice显示文摘 | Annette E Markus B Thomas P | 2007 | Hepatology2007，45，2： | 1 |
| 6 | Secretory expression and characterization of insulin in Pichia pastoris显示文摘 | Annette F P Morten H | 1999 | Biotechnol Appl Biochem1999，29，： | 1 |
| 7 | Deletion of the gene encoding p60 in Listeria monocytogenes leads to abnormal cell division and loss of actin-based motility显示文摘 | SABINE P ANNETTE K M IVAYLO G | 2003 | Infect Immun2003，71，6： | 1 |
| 8 | Reesttabish in freshwater wetlands in Denmark显示文摘 | CARL C H ANNETTE B P | 2006 | Ecological Engineering2006，，9： | 1 |
| 9 | Improved RNA extraction and one-tube RT-PCR assay simultaneous detection of control plant RNA plus several viruses in plant extracts显示文摘 | Elisa P Katherine Helmeczy | 2000 | Journal of Virological Methodes2000，90，： | 1 |
| 10 | Deletion of the Gene Encoding p60 in Listeria monocytogenes leads to abnormal cell division and loss of actin-based motility显示文摘 | SABINE P ANNETTE K M IVAYLO G | 2003 | Infect Immun2003，71，6： | 1 |
| 11 | From soil to gut: Bacillus cereus and its food poisoning toxins 显示文摘 | LOTTE P STENFORS ARNESEN ANNETTE FAGERLUND PER E GRANUM | 2008 | FEMS Microbiol Rev2008，32，4： | 1 |
| 12 | Particulate air pollution and risk of ST-segment depression during repeated submaximal exercise tests among subjects with coronary heart disease: the Exposure andRisk Assessment for Fine and Ultrafine Particles in Ambient Air (ULTRA) study显示文摘 | Juha P Annette P Gerard H | 2002 | Circulation2002，106，8： | 1 |
| 13 | Improved RNA extrac- tion and one-tube RT-PCR assay for simultaneous detec- tion of control plant RNA plus several viruses in plant extracts 显示文摘 | Annette N Elisa P Katherine H | 2000 | Journal of Virological Methods2000，90，1： | 1 |
| 14 | Assessing the environmental impacts of freshwater consumption in LCA 显示文摘 | STEPHAN P ANNETTE K STEFANIE H | 2009 | Enxironmental Science and Technology2009，43，11： | 1 |
| 15 | Deletion of the Gene Encoding p60 in Listeria monocytogenes lead to abnormal cell division and lose'actin-based motility显示文摘 | Sabine P Annette K M Ivaylo G | 2003 | Infect Immun2003，71，6： | 1 |
| 16 | Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape 显示文摘 | Andrew K S David A P Annette Oxenius | 2000 | Stem Cells2000，18，4： | 1 |
| 17 | Peptide surfactants (pepfactants) for switchable foams and emulsions 显示文摘 | Andrew S M Annette F D Anton P J | 2007 | Chem Eng2007，2，5： | 1 |
| 18 | Detection of rancidity in freeze stored turkey meat using acommercial gas-sensor array system显示文摘 | John-Erik H Frank L Jens P W Annette V | 2006 | Sensors and Actuators2006，116，12： | 1 |
| 19 | A Method for Measuring Team Skills 显示文摘 | Annett J Cunnlngham D Mathias -Jones P | 2000 | Ergonomics2000，43，8： | 1 |
| 20 | Generation o f transgenic wheat (Triticum aestivum L)for constitutive accumulation of an Aspergillus phytase显示文摘 | Henrik B P Annette O Sren K R | 2000 | Molecular Breeding2000，6，： | 1 |
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