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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Concomitant gonadotropin-releasing hormone agonist and menotropin treatment for the synchronized induction of multiple follicles显示文摘 | Palermo R Amodeo G Navot D | 1988 | Fertil Steril1988，49，2： | 1 |
| 3 | F- unct ional characterization and localization of AQP3 in the human colon 显示文摘 | SILBERSTEIN C KIERBEL A AMODEO G | 1999 | Braz J Med Biol Res1999，32，： | 1 |
| 4 | Erythrocyte deformability and nitric oxide metabolites in athletes before and after a cardiopul- monary test显示文摘 | Caimi G Canino B Amodeo G | 2009 | Clin J Sport Med2009，19，4： | 1 |
| 5 | The role of aquaporins and membrane damage in chilling and hydro gen peroxide induced changes in the hydraulic conductance of maize roots 显示文摘 | Aroca R Amodeo G Fernandez-Illescas S | 2005 | Plant Physiol2005，137，1： | 1 |
| 6 | The role of aqua- porins and membrane damage in chilling and hydrogen per- oxide induced changes in the hvdraulic conductance of maize roots 显示文摘 | Aroca R Amodeo G Fernandez I S | 2005 | Plant Physio12005，137，： | 1 |
| 7 | Sensitivity analysis of differential absorption lidar measurements in the mid-infrared region显示文摘 | AMODEO A DI G P | 2000 | Applied Optics2000，39，36： | 1 |
| 8 | The beneficial vortex and best spatial arrangement in total extracardiac cavopulmonary connection显示文摘 | AMODEO A GRIGIONI M OPPIDO G | 2002 | J Thorac Cardiovasc Surg2002，124，3： | 1 |
| 9 | The beneficialvortex and best spatial arrangement in total extracardiaccavopulmonary connection显示文摘 | Amodeo A Grigioni M Oppido G | 2002 | J Thorac Cardiovasc Surg2002，124，3： | 1 |
| 10 | The water permeability of Arabidopsis plasma membrane is regulated by divalent cations and pH显示文摘 | Gerbeau P Amodeo G Henzler T | 2002 | Plant J2002，，30： | 1 |
| 11 | The role of aquaporins and membrane damage in chilling and hydrogen peroxide induced changes in the hydraulic conductance of maize roots显示文摘 | Aroca R Amodeo G Fernandez-Illescas S | 2005 | Plant Physiol2005，137，1： | 1 |
| 12 | Functional characterization and localization of AQP3 in the human colon 显示文摘 | SILBERSTEIN C KIERBEL A AMODEO G | 1999 | Braz J Med Biol Res1999，32，10： | 1 |
| 13 | Functional charac- terization and localization of AQP3 in the human colon显示文摘 | Silberstein C Kierbel A Amodeo G | 1999 | Braz J Med Biol Res1999，32，10： | 1 |
| 14 | The role of Aquaporins and membrane damage in chilling and hydrogen peroxide induced changes in the hydraulic conductance of maize roots显示文摘 | Aroca R Amodeo G Fernandez-Illescas S | 2005 | Plant Physiology2005，137，1： | 1 |
| 15 | Functional characterization and localization of AQP3 in the human colon 显示文摘 | Silberstein C Kierbel A Amodeo G | 1999 | Braz J Med Biol Res1999，32，10： | 1 |
| 16 | Solution structure of human calcitonin in membrane - mimetic environment: The role of the amphipathic helix显示文摘 | Motta A Andreotti G Amodeo P | 1998 | Proteins1998，32，3： | 1 |
| 17 | The beneficial vortex and best spatial arrangement in total extracardiac cavopulmonary connection显示文摘 | Amodeo A Grigioni M Oppido G | 2002 | J Thorac Cardiovasc Surg2002，124，3： | 1 |
| 18 | Comparison of single-pill strategies first line in hypertension: perindopril/amlo- dipine versus valsartan/amlodipirte显示文摘 | Giuseppe Mancia G Asmar R Amodeo C | 2015 | J Hypertens2015，33，2： | 1 |
| 19 | The role of aquaporins and membrane damage in chilling and hydrogen peroxide induced changes in the hydraulic conductance of maize roots显示文摘 | Aroca R Amodeo G Fernandez-Illescas S | 2005 | Plant Physiol2005，137，： | 1 |
| 20 | Intractable haematuria: long-term results after selective embolization of the internal iliac arteries显示文摘 | Liguori G Amodeo A Mucelli FP | 2010 | BJU Int2010，106，4： | 1 |
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