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| 1 | Epstein-Barr virus is related with 5-aminosalicylic acid, tonsillectomy, and CD19^+ cells in Crohn's disease显示文摘AIM: To study anti-Epstein-Barr virus(EBV) Ig G antibodies in Crohn′s disease in relation to treatment, immune cells, and prior tonsillectomy/appendectomy.METHODS: This study included 36 CD patients and 36 healthy individuals(controls), and evaluated different clinical scenarios(new patient, remission and active disease), previous mucosa-associated lymphoid tissue removal(tonsillectomy and appendectomy) and therapeutic regimens(5-aminosalicylic acid, azathioprine, anti-tumor necrosis factor, antibiotics, and corticosteroids). T and B cells subsets in peripheral blood were analyzed by flow cytometry(markers included: CD45, CD4, CD8, CD3, CD19, CD56, CD2, CD3, TCRαβ and TCRγδ) to relate with the levels of anti-EBV Ig G antibodies, determined by enzyme-linked immunosorbent assay.RESULTS: The lowest anti-EBV Ig G levels were observed in the group of patients that were not in a specific treatment(95.4 ± 53.9 U/m L vs 131.5 ± 46.2 U/m L, P = 0.038). The patients that were treated with 5-aminosalicylic acid showed the highest anti-EBV Ig G values(144.3 U/m L vs 102.6 U/m L, P = 0.045). CD19+ cells had the largest decrease in the group of CD patients that received treatment(138.6 vs 223.9; P = 0.022). The analysis of anti-EBV Ig G with respect to the presence or absence of tonsillectomy showed the highest values in the tonsillectomy group of CD patients(169.2 ± 20.7 U/m L vs 106.1 ± 50.3 U/m L, P = 0.002). However, in the group of healthy controls, no differences were seen between those who had been tonsillectomized and subjects who had not been operated on(134.0 ± 52.5 U/m L vs 127.7 ± 48.1 U/m L, P = 0.523).CONCLUSION: High anti-EBV Ig G levels in CD are associated with 5-aminosalicylic acid treatment, tonsillectomy, and decrease of CD19+ cells. | Juan C Andreu-Ballester Rafael Gil-Borrás Carlos García-Ballesteros Ignacio Catalán-Serra Victoria Amigo Virgina Fernández-Fígares Carmen Cuéllar | 2015 | World Journal of Gastroenterology2015，21，15： | 3 |
| 2 | 激光表面熔化对Ti-30Nb-4Sn合金晶体织构、显微组织、弹性模量和硬度的影响显示文摘骨科植入物的生物相容性与其弹性模量和表面性能密切相关。本研究的目的是阐明冷轧、再结晶和表面激光熔化(LSM)对双相(α″+β)Ti-30Nb-4Sn合金显微组织和力学性能的影响。对冷轧态基体进行X射线衍射织构分析(XRD)显示有[302]α″//ND织构成分,而对再结晶态基体的分析显示有[302]α″//ND和[110]α″//ND织构成分。XRD不能直接检测出β相织构,但是通过考虑α′′相和β相之间的位向关系可成功预测出[111]β||ND织构的存在。纳米压痕测试结果表明,冷轧态基体的弹性模量(63 GPa)低于再结晶态基体(74 GPa)。根据已有文献和本文研究结果,认为这种差异是由冷变形过程中晶体缺陷的引入造成的。纳米压痕/EBSD分析表明,纳米压痕结果不受晶体取向的影响。LSM对变形合金硬度、弹性模量和晶体织构产生的变化类似于再结晶热处理产生的变化,均在表面和基体之间产生刚度梯度。 | Leonardo FANTON Nelson Batista de LIMA Emilio Rayon ENCINAS Vicente Amigo BORRAS Conrado Ramos Moreira AFONSO Joao Batista FOGAGNOLO | 2020 | Transactions of Nonferrous Metals Society of China2020，30，2： | 2 |
| 3 | Acute activation or Maxi-Kchannels (hSlo) by estradiol binding to the beta subunit显示文摘 | Rojas P Amigo J | 1999 | Scince1999，285，： | 1 |
| 4 | Enrichment of benzo pyrene in vegetable oils and determination by HPLC - FL 显示文摘 | Vazquez Troche S Garcla Falc6n M S Gonzalaz Amigo S | 2000 | Talanta2000，51，6： | 1 |
| 5 | Expression and regulation of scavenger receptor class B type I ( SR - BI) in gall bladder epithelium 显示文摘 | MIQUEL JF MORENO M AMIGO L | 2003 | Gut2003，52，7： | 1 |
| 6 | Acute activation of Maxi-K channels(h Slo)by estradiol binding to theβsubunit显示文摘 | Valverde MA Rojas P Amigo J | 1999 | Science1999，285，： | 1 |
| 7 | Hepatic overexpression of sterol carder protein- 2 inhibits VLDL production and reciprocally enhances biliary lipid secretion显示文摘 | Amigo L Zanlungo S Miquel JF | 2003 | Lipid Res2003，44，： | 1 |
| 8 | Homozygous HLA-G·0105N Healthy Individuals Indicate that Membrane associated HLA G1 Molecule is not Necessary for Survival显示文摘 | Casro M J Morales P Rojo Amigo R | 2000 | Tissue Antigens2000，56，3： | 1 |
| 9 | Identification of the ini- tial binding sites of αs2- casein f ( 183 - 207 ) and effect on bacterial membranes and cell morphology 显示文摘 | Lopez - ExpositoI Amigo L Recio I | 2008 | Biochim Biophys Acta2008，1778，10： | 1 |
| 10 | Homozygous HLA-G * 0105N healthy individuals indicate that membrane-anchored HLA-G1 molecule is not necessary for survival 显示文摘 | CASRO M J MORALES P ROJO AMIGO | 2000 | Tissue Antigens2000，56，3： | 1 |
| 11 | Azacitidine adverse effects in patients with myelodysplastic syndromes 显示文摘 | San Miguel Amigo L Franco Osorio R Mercadal Vilchez S | 2011 | AdvTher2011，28，14： | 1 |
| 12 | Cryptographically secure substitutions based on the Approximation of mixing Maps显示文摘 | SZCZEPANSKI J AMIGo J Michalek T Kacarev L | 2005 | IEEE Trans CAS- I2005，52，： | 1 |
| 13 | Synergistic effect between different milk - derived peptides and proteins 显示文摘 | Lopez - ExpositoI Pellegrini A Amigo L | 2008 | J Dairy Sci2008，91，6： | 1 |
| 14 | Modulation of intrahepatic cholesterol trafficking:evidence by in vivo antisense treatment for the involvement of sterol carrier protein-2 in newly synthesized cholesterol transport into rat bile显示文摘 | Puglielli L Rigotti A Amigo L | 1996 | Biochem J1996，317，3： | 1 |
| 15 | Influence of processing variables on mechanical characteristics of sunlight aged polyester-glass fiber composites 显示文摘 | SEGOVIA F FERRER C SALVADOR M D AMIGO V | 2001 | Polymer Degradation and Stability2001，71，： | 1 |
| 16 | Sterol carrier protein 2 gene transfer changes lipid metabolism and enterohepatic sterol circulation in mice显示文摘 | Zanlungo S Amigo L Mendoza H | 2000 | Gastroenterology2000，119，6： | 1 |
| 17 | A chaosbased approach to the design of cryptographically secure substitutions显示文摘 | AMIGo J SZCZEPANSKI J KACAREV L | 2005 | Physics Letters A2005，343，： | 1 |
| 18 | A GATA - 1 - regulated microRNA locus essential for erythropoiesis 显示文摘 | Dore L C Amigo J D Dos Santos C O | 2008 | Proc Natl Acad Sci USA2008，105，9： | 1 |
| 19 | Discrete chaos-I: theory显示文摘 | Kocarev L Szczepanski J Amigo J M | 2006 | IEEE Transactions on Circuits and Systems I: Fundamental Theory and Applications2006，53，6： | 1 |
| 20 | Enrichment of canalicular membrane with cholesterol and sphingomyelin prevents bile salt-induced hepatic damage显示文摘 | Amigo L Mendoza H Zanlungo S | 1999 | Journal of Lipids Research1999，40，3： | 1 |
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