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| 1 | Imaging and radiological interventions in extra-hepatic portal vein obstruction显示文摘Extrahepatic portal vein obstruction(EHPVO) is a primary vascular condition characterized by chronic long standing blockage and cavernous transformation of portal vein with or without additional involvement of intrahepatic branches, splenic or superior mesenteric vein. Patients generally present in childhood with multiple episodes of variceal bleed and EHPVO is the predominant cause of paediatric portal hypertension(PHT) in developing countries. It is a pre-hepatic type of PHT in which liver functions and morphology are preserved till late. Characteristic imaging findings include multiple parabiliary venous collaterals which form to bypass the obstructed portal vein with resultant changes in biliary tree termed portal biliopathy or portal cavernoma cholangiopathy. Ultrasound with Doppler, computed tomography, magnetic resonance cholangiography and magnetic resonance portovenography are non-invasive techniques which can provide a comprehensive analysis of degree and extent of EHPVO, collaterals and bile duct abnormalities. These can also be used to assess in surgical planning as well screening for shunt patency in post-operative patients. The multitude of changes and complications seen in EHPVO can be addressed by various radiological interventional procedures. The myriad of symptoms arising secondary to vascular, biliary, visceral and neurocognitive changes in EHPVO can be managed by various radiological interventions like transjugular intra-hepatic portosystemic shunt, percutaneous transhepatic biliary drainage, partial splenic embolization, balloon occluded retrograde obliteration of portosystemic shunt(PSS) and revision of PSS. | Sudheer S Pargewar Saloni N Desai S Rajesh Vaibhav P Singh Ankur Arora Amar Mukund | 2016 | World Journal of Radiology2016，8，6： | 8 |
| 2 | Endoscopic ultrasound staging for early esophageal cancer: Are we denying patients neoadjuvant chemo-radiation?显示文摘AIM To evaluate the accuracy of endoscopic ultrasound(EUS) in early esophageal cancer(EC) performed in a highvolume tertiary cancer center. METHODS A retrospective review of patients undergoing esophagectomy was performed and patients with c T1 N0 and c T2 N0 esophageal cancer by EUS were evaluated. Patient demographics, tumor characteristics, and treatment were reviewed. EUS staging was compared to surgical pathology to determine accuracy of EUS. Descriptive statistics was used to describe the cohort. Student's t test and Fisher's exact test or χ~2 test was used to compare variables. Logistic regression analysis was used to determine if clinical variables such as tumor location and tumor histology were associated with EUS accuracy.RESULTS Between 2000 and 2015, 139 patients with clinical stage Ⅰ or Ⅱ?A esophageal cancer undergoing esophagectomy were identified. There were 25(18%) female and 114(82%) male patients. The tumor location included the middle third of the esophagus in 11(8%) and lower third and gastroesophageal junction in 128(92%) patients. Ninety-three percent of patients had adenocarcinoma. Preoperative EUS matched the final surgical pathology in 73/139 patients for a concordance rate of 53%. Twenty-nine patients(21%) were under-staged by EUS; of those, 19(14%) had unrecognized nodal disease. Positron emission tomography(PET) was used in addition to EUS for clinical staging in 62/139 patients. Occult nodal disease was only found in 4 of 62 patients(6%) in whom both EUS and PET were negative for nodal involvement. CONCLUSION EUS is less accurate in early EC and endoscopic mucosal resection might be useful in certain settings. The addition of PET to EUS improves staging accuracy. | Carrie Luu Marisa Amaral Jason Klapman Cynthia Harris Khaldoun Almhanna Sarah Hoffe Jessica Frakes Jose M Pimiento Jacques P Fontaine | 2017 | World Journal of Gastroenterology2017，23，46： | 8 |
| 3 | Association of NFKB1 gene polymorphism (rs28362491) with levels of inflammatory biomarkers and susceptibility to diabetic nephropathy in Asian Indians显示文摘AIM To investigate the association of NFKB1 gene-94 ATTG insertion/deletion(rs28362491) polymorphism with inflammatory markers and risk of diabetic nephropathy in Asian Indians.METHODS A total of 300 subjects were recruited(100 each), normoglycemic,(NG); type 2 diabetes mellitus(T2DM) without any complications(DM) and T2 DM with diabetic nephropathy [DM-chronic renal disease(CRD)]. Analysis was carried out by polymerase chain reaction-restriction fragment length polymorphism and ELISA. Pearson's correlation, analysis of variance and logistic regression wereused for statistical analysis.RESULTS The allelic frequencies of-94 ATTG insertion/deletion were 0.655/0.345(NG), 0.62/0.38(DM) and 0.775/0.225(DM-CRD). The-94 ATTG ins allele was associated with significantly increased levels of urinary monocyte chemoattractant protein-1(u MCP-1); u MCP-1(P = 0.026) and plasma tumor necrosis factor-alpha(TNF-α); TNF-α(P = 0.030) and almost doubled the risk of diabetic nephropathy(OR = 1.91, 95%CI: 1.080-3.386, P = 0.025).CONCLUSION-94 ATTG ins/ins polymorphism might be associated with increased risk of developing nephropathy in Asian Indian subjects with diabetes mellitus. | Amar Gautam Stuti Gupta Mohit Mehndiratta Mohini Sharma Kalpana Singh Om P Kalra Sunil Agarwal Jasvinder K Gambhir | 2017 | World Journal of Diabetes2017，8，2： | 4 |
| 4 | Scaling behaviour in the growth of companies显示文摘 | Stanley M H R Amaral L A N Buldyrev S V Havlin S Leschhorn H Maass P Salinger M A Stanley H E | 1996 | Nature1996，379，： | 1 |
| 5 | Structural and Magnetic Study of Self-doped La1-x-yCaxφyMnO3显示文摘 | Figueiras F Araùjo J P Amaral V S | 2004 | Journal of Magnetism and Magnetic Materials2004，，： | 1 |
| 6 | A SYBR green real-time PCR assay to detect and quantify pork meat in processed poultry meat products显示文摘 | SOARES S AMARAL J S OLIVEIRA M B P P | 2013 | Meat Science2013，94，： | 1 |
| 7 | Palhogenesis and pharmacological strategies for mitigating secondary damage in acute spinal cord injury 显示文摘 | Amar A P Levy M L | 1999 | Neurosurgery1999，44，5： | 1 |
| 8 | Depressive symptoms,anxiety,and quality of life in women with pelvic endometriosis显示文摘 | Sepulcri Rde P Amaral VF | 2009 | Eur J Obstet Gynecol Reprod Biol2009，142，1： | 1 |
| 9 | Metabolic endotoxemia initiates obesity and insulin resistance 显示文摘 | CANI P D AMAR J IGLESIAS M A | 2007 | Diabetes2007，56，7： | 1 |
| 10 | Total parenteral nutrition with glutamine in bone marrow transplantation and other clinical applications显示文摘 | Schloerb P R Amare M | 1993 | J Parenter Enteral Nutr1993，17，5： | 1 |
| 11 | Bayesian Approach to Parameter Estimation of the Generalized Pareto Distribution显示文摘 | P de Zea Bermudez M A Amaral Turkman | 2003 | Test (Journal of Statistics and Probability)2003，12，1： | 1 |
| 12 | Dicyclohexano-18-Crown-6 in Butanol-Octanol Mixture: A Promising Extractant of Sr( Ⅱ ) From Nitric Acid Medium显示文摘 | Amar K Mohapatra P K Pathak P N | 1997 | Talanta1997，45，： | 1 |
| 13 | Efficient multigram synthesis of the repeating unit of gallic aeid-triethylene glycol dendrimers 显示文摘 | AMARAL S P FERNANDEZ-VILLAMARIN M CORREA J | 2011 | Organic Letters2011，13，17： | 1 |
| 14 | Trypsin-like enzyme from intestine and pyloric caeca of spotted goaffish ( Pseudupeneus maeulatus ) 显示文摘 | Souza A A G Amaral I P G Santo A R E | 2007 | Food Chem2007，100，4： | 1 |
| 15 | A model for the growth dynamics of economic organizations显示文摘 | Amaral L A N Gopikrishnan P Plerou V Stanley H E | 2001 | Physica A2001，299，： | 1 |
| 16 | Fluorescence in situ hybridization : a highly efficient technique of molecular diagnosis and predication for disease course in patients with myeloid leukemias 显示文摘 | Amare P S Baisane C Saikia T | 2001 | Cancer Genet Cytogenet2001，31，2： | 1 |
| 17 | Excess membrane cholesterol alters human gallbladder muscle contractility and membrane fluidity 显示文摘 | Chen Q Amaral J Biancani P | 1999 | Gastroenterology1999，116，3： | 1 |
| 18 | 显示文摘 | Strathmann H Kock K Amar P | 1975 | Desalina tion1975，16，2： | 1 |
| 19 | Optical properties of LiGaTiO4:Fe^3+显示文摘 | SOSMAN L P ABRITTA T AMARAL M R | 1998 | Solid State Commun1998，105，2： | 1 |
| 20 | Pre-dictive value of serum prolactin levels measured immediate-ly after transsphenoidal surgery显示文摘 | COULDWELL W T CHEN J C | 2002 | J Neurosurg2002，97，2： | 1 |
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