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121篇 您的检索式:作者名="ALPING A"
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1Relation of atrophic gastritis with Helicobacter pylori-CagA^+ and interleukin-1 gene polymorphisms显示文摘AIM: To determine the association of Helicobacter pylori (H pylori) CagA+ infection and pro-inflammatory poly-morphisms of the genes interleukin (IL)-1RN and IL-1B with the risk of gastric atrophy and peptic ulcers in a dyspeptic population in Costa Rica, a country with high incidence and mortality of gastric cancer. METHODS: Seven biopsy specimens, a fasting blood sample and a questionnaire concerning nutritional and sociodemographic factors were obtained from 501 con-secutive patients who had undergone endoscopy for dyspeptic symptoms. A histopathological diagnosis was made. Pepsinogen concentrations were analyzed by enzyme linked immunosorbent assay (ELISA). Infection with H pylori CagA+ was determined by serology and polymerase chain reaction (PCR). IL-1B and IL-1RN polymorphisms genotyping was performed by PCR-restriction fragment length polymorphism (PCR-RFLP)and PCR respectively. RESULTS: In this dyspeptic population, 86% were H pylori positive and of these, 67.8% were positive for CagA. Atrophic antral gastritis (AAG) was associated with CagA+ status [odd ratio (OR) = 4.1; P < 0.000] and fruit consumption (OR = 0.3; P < 0.00). Atrophic body gastritis (ABG) was associated with pepsinogen PGI/PGII < 3.4 (OR = 4.9; P < 0.04) and alcohol consumption (OR = 7.3; P < 0.02). Duodenal ulcer was associated with CagA+ (OR = 2.9; P < 0.04) and smoking (OR = 2.4; P < 0.04). PGI < 60 μg/L as well as PGI/PGII < 3.4 were associated with CagA+. CONCLUSION: In a dyspeptic population in Costa Rica, H pylori CagA+ is not associated with ABG, but it is a risk factor for AAG. The pro-inflammatory cytokine poly-morphisms IL-1B + 3945 and IL-1RN are not associated with the atrophic lesions of this dyspeptic population.Rafaela Sierra Clas Une Vanessa Ramírez Warner Alpízar-Alpízar María I González José A Ramírez Antoine de Mascarel Patricia Cuenca Guillermo Pérez-Pérez Francis Mégraud 2008World Journal of Gastroenterology2008,14,42:2
2The effects of the novel anti-anginal RS43285 on, and pH in a canine model of transient my ocardial ischaemia显示文摘ALLEY M C ALPS B J N KILPATRICK A T 1987Biochem Soc Trans1987,15,6:1
3A modified yoga-based exercise program in hemodialysis patients: a randomized controlled study显示文摘Yurtkuran M Alp A Yurtkuran M 2007Complement Ther Med2007,15,3:1
4CYP17 and CYP2C19 gene polymorphisms in patients with endometriosis显示文摘Bozdag G Alp A Saribas Z 2010Reprod Biomed Online2010,20,2:1
5Colour Doppler imaging of the orbital vasculature in Graves' disease with computed tomographic correlation显示文摘Alp MN Ozgen A Can I 2000BrJ Ophthalmol2000,84,9:1
6Ventilator associated pneumonia and infection control显示文摘Alp E Voss A 2006Ann Clin Microbiol Antimicrob2006,5,1:1
7Bioleaching of complex zinc sulphides using mesophilic and thermophilic bacteria:Comparative importance of pH and iron显示文摘Deveci H Akcil A Alp I 2004Hydrometallurgy2004,73,34:1
8Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase Ⅰ overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice显示文摘Alp N J McAteer M A Khoo J 2004Arterioscler Thromb Vasc Biol2004,24,3:1
9Relationship between blood pressure and outdoor temperature in a large sample of elderly individuals:the three-city study显示文摘Alpérovitch A Lacombe J M Hanon O 0,,01:1
10Risk factors for nosoco-mial infection and mortality in bum patients: 10 years ofexperience at a university hospital 显示文摘Alp E Coruh A Gunay G K 2012Journal of BumCare & Research2012,33,3:1
11A rapid troponin-I-based protocol for assessing acute chest pain显示文摘ALP N J BELL J A M Shahi 2001QJM2001,94,12:1
12Conjunctival rotation autograft for primary pterygium 显示文摘Alp BN Yanyali A Ay GM Keskin O 2002Ophthalmologica2002,216,5:1
13Utility of a commercial quantitative hepatitis C virus core antigen assay in a diagnostic laboratory setting显示文摘Ergunay K Sener B Alp A 2011Diaqn Microbiology Infect Dis2011,70,4:1
14TAR-cointegration neural network model:An empirical analysis of exchange rates and stock returns显示文摘BILDIRICI M ALP E A ERSIN O O 2010Expert Systems with Applications2010,37,1:1
15Ant colony opimization for the single modelU-type assembly line balancing problem显示文摘Sabuncuoglu I Erel E Alp A 2009International Journal ofProduction Economics2009,120,2:1
16Electrical noise measurement on laser diodes for monitoring of optical feedback and mode hopping 显示文摘ANDREKSON P A ANDERSSON P ALPING A 1986Electron Lett1986,22,:1
17Reduced vascular NO bioavailability in diabetes increases platelet activation in vivo 显示文摘Schafer A Alp N J Cai S 2004Arterioscler Thromb Vasc Biol2004,24,9:1
18Human model simulating right ventricular outflow tract tachycardia by high - frequency stimulation in the left pulmonary artery: autonomies and idiopathic ventricular ar- rhythmias 显示文摘Hasdemir C Alp A Aydin M 2009J Cardiovasc Electrophysiol2009,20,7:1
19Phonon density of states of iron up to 153 Gigapascals显示文摘Mao H.K Xu J Struzhkin V.V Shu J.F Hemley R.J Sturhahn W Wu M.Y Alp E.E Vocadlo L Alfe D Price G.D Gillan M.J Schwoerer-B(o)hning M H(a)usermann D Eng P Shen G Giefers H Lubbers R Wortmann G 0,,:1
20Reproducibility of endometrial intraepithelial neoplasia diagnosis is good, but influenced by the diagnostic style of pathologists 显示文摘Usubutun Alp Mutter GL Saglam A 2012Mod Pathol2012,10,:1
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