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| 1 | Real time endoscopic ultrasound elastography and strain ratio in the diagnosis of solid pancreatic lesions显示文摘AIM To evaluate the accuracy of the elastography score combined to the strain ratio in the diagnosis of solid pancreatic lesions(SPL). METHODS A total of 172 patients with SPL identified by endoscopic ultrasound were enrolled in the study to evaluate the efficacy of elastography and strain ratio in differentiating malignant from benign lesions. The semi quantitative score of elastography was represented by the strain ratio method. Two areas were selected, area(A) representing the region of interest and area(B) representing the normal area. Area(B) was then divided by area(A). Sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV), and accuracy were calculated by comparing diagnoses made by elastography, strain ratio and final diagnoses.RESULTS SPL were shown to be benign in 49 patients and malignant in 123 patients. Elastography alone had a sensitivity of 99%, a specificity of 63%, and an accuracy of 88%, a PPV of 87% and an NPV of 96%. The best cut-off level of strain ratio to obtain the maximal area under the curve was 7.8 with a sensitivity of 92%, specificity of 77%, PPV of 91%, NPV of 80% and an accuracy of 88%. Another estimated cut off strain ratio level of 3.8 had a higher sensitivity of 99% and NPV of 96%, but with less specificity, PPV and accuracy 53%, 84% and 86%, respectively. Adding both elastography to strain ratio resulted in a sensitivity of 98%, specificity of 77%, PPV of 91%, NPV of 95% and accuracy of 92% for the diagnosis of SPL. CONCLUSION Combining elastography to strain ratio increases the accuracy of the differentiation of benign from malignant SPL. | Hussein Okasha Shaimaa Elkholy Ramy El-Sayed Mohamed-Naguib Wifi Mohamed El-Nady Walid El-Nabawi Waleed A El-Dayem Mohamed I Radwan Ali Farag Yahya El-sherif Emad Al-Gemeie Ahmed Salman Mohamed El-Sherbiny Ahmed El-Mazny Reem E Mahdy | 2017 | World Journal of Gastroenterology2017，23，32： | 11 |
| 2 | Prognostic factors in patients with advanced cholangiocarcinoma: Role of surgery, chemotherapy and body mass index显示文摘AIM: To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS: A retrospective review of the medical records of 55 patients diagnosed with cholangio- carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to determine the impact of surgery, chemotherapy, body mass index, bilirubin level and other factors on survival. RESULTS: The median survival of all patients was 8.57 mo (0.03-105.2). Univariate analysis showed that low bilirubin level (< 10 mg/dL), radical surgery and chemotherapy administration were significantly associated with better survival (P = 0.012, 0.038 and 0.038, respectively). In subgroup analysis on patients who had no surgery, chemotherapy administration prolonged median survival significantly (17.0 mo vs 3.5 mo, P = 0.001). Multivariate analysis identifiedonly low bilirubin level < 10 mg/dL and chemotherapy administration as independent predictors associated with better survival (P < 0.05). CONCLUSION: Our data show that palliative and postoperative chemotherapy as well as a bilirubin level < 10 mg/dL are independent predictors of a significant increase in survival in patients with cholangiocarcinoma. | Mirna H Farhat Ali I Shamseddine Ayman N Tawil Ghina Berjawi Charif Sidani Wael Shamseddeen Kassem A Barada | 2008 | World Journal of Gastroenterology2008，14，20： | 9 |
| 3 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 4 | Drainage vs. non-drainage after cholecystectomy for acute cholecystitis:a retrospective study显示文摘Many surgeons practice prophylactic drainage after cholecystectomy without reliable evidence,this study was conducted to answer the question whether to drain or not to drain after cholecystectomy for acute calculous cholecystitis.A retrospective review of all patients who had cholecystectomy for acute cholecystitis in Aseer Central Hospital,Abha,Saudi Arabia,was conducted from April 2010 to April 2012.Data were extracted from hospital case files.Preoperative data included clinical presentation,routine investigations and liver function tests.Operative data included excessive adhesions,bleeding,bile leak,and drain insertion.Complicated cases such as pericholecystic collections,mucocele and empyema were also reported.Patients who needed therapeutic drainage were excluded.Postoperative data included hospital stay,volume of drained fluid,time of drain removal,and drain site problems.The study included 103 patients allocated into two groups;group A(n = 38) for patients with operative drain insertion and group B(n = 65) for patients without drain insertion.The number of patients with preoperative diagnosis of acute non-complicated cholecystitis was significantly greater in group B(80%) than group A(36.8%)(P < 0.001).Operative time was significantly longer in group A.All patients who were converted from laparoscopic to open cholecystectomy were in group A.Multivariate analysis revealed that hospital stay was significantly(P < 0.001) longer in patients with preoperative complications.There was no added benefit for prophylactic drain insertion after cholecystectomy for acute calculous cholecystitis in non-complicated or in complicated cases. | Mohammed A Bawahab Walid M Abd El Maksoud Saeed A Alsareii Fahad S Al Amri Hala F Ali Abdul Rahman Nimeri Abdul Rahman M Al Amri Adel A Assiri Mohammed I Abdul Aziz | 2014 | The Journal of Biomedical Research2014，28，3： | 3 |
| 5 | Split-dose menthol-enhanced PEG vs PEG-ascorbic acid for colonoscopy preparation显示文摘AIM:To compare the efficacy and palatability of 4L polyethylene glycol electrolyte(PEG)plus sugar-free menthol candy(PEG+M)vs reduced-volume 2 L ascorbic acid-supplemented PEG(Asc PEG).METHODS:In a randomized controlled trial setting,ambulatory patients scheduled for elective colonoscopy were prospectively enrolled.Patients were randomized to receive either PEG+M or Asc PEG,both splitdosed with minimal dietary restriction.Palatability was assessed on a linear scale of 1 to 5(1=disgusting;5=tasty).Quality of preparation was scored by assignment-blinded endoscopists using the modified Aronchick and Ottawa scales.The main outcomes were the palatability and efficacy of the preparation.Secondary outcomes included patient willingness to retake the same preparation again in the future and completion of the prescribed preparation.RESULTS:Overall,200 patients were enrolled(100patients per arm).PEG+M was more palatable than Asc PEG(76%vs 62%,P=0.03).Completing the preparation was not different between study groups(91%PEG+M vs 86%Asc PEG,P=0.38)but more patients were willing to retake PEG+M(54%vs 40%respectively,P=0.047).There was no significant difference between PEG+M vs Asc PEG in adequate cleansing on both the modified Aronchick(82%vs77%,P=0.31)and the Ottawa scale(85%vs 74%,P=0.054).However,PEG+M was superior in the left colon on the Ottawa subsegmental score(score0-2:94%for PEG+M vs 81%for Asc PEG,P=0.005)and received significantly more excellent ratings than Asc PEG on the modified Aronchick scale(61%vs 43%,P=0.009).Both preparations performed less well in afternoon vs morning examinations(inadequate:29%vs 15.2%,P=0.02).CONCLUSION:4 L PEG plus menthol has better palatability and acceptability than 2 L ascorbic acidPEG and is associated with a higher rate of excellentpreparations;Clinicaltrial.gov identifier:NCT01788709. | Ala I Sharara Ali H Harb Fayez S Sarkis Jean M Chalhoub Rami Badreddine Fadi H Mourad Mahmoud Othman Omar Masri | 2015 | World Journal of Gastroenterology2015，21，6： | 2 |
| 6 | Comparing emulsion polymerization of methacrylate-monomers with different hydrophilicitty显示文摘 | A M I mroz Ali Klaus Tauer Mlios Sedlak | 2005 | Polymer2005，46，： | 1 |
| 7 | ' Abasin -95' , a new oilseed rape cultivar developed through induced mutations 显示文摘 | Shah S A Ali I Rahman K | 2001 | Mut Breed Newsletter2001，45，： | 1 |
| 8 | Advanced interpolation techniques for NC machines 显示文摘 | BEDI S ALI I QUAN N | 1993 | Journal of Engineering for Industry1993，115，8： | 1 |
| 9 | Potentiation of the effect of erlotinib by genistein in pancreatic cancer: the role of Akt and nuclear factor-kappaB 显示文摘 | EIRAYES B F ALI S ALI I F | 2006 | Cancer Res2006，66，10： | 1 |
| 10 | Experimental and numerical investigation on the behavior of transverse limited micro-grooves in EHL point contacts显示文摘 | Ali F Kaneta M K~upka I | 2015 | Tribology International2015，84，： | 1 |
| 11 | Space-time spectral model for object detection in dynamic textured background显示文摘 | ALI I MILLE J TOUGNE L | 2012 | Pattern recognition letters2012，33，13： | 1 |
| 12 | Current status and future prospects of epizootic hacmorrhagic disease of deer-a review 显示文摘 | Aradaib I Ali N | 2004 | Veterinarski Arhiv2004，74，1： | 1 |
| 13 | Defluoridation of wastewaters u- sing waste carbon slurry显示文摘 | GUPTA V ALI I SAINI V | 2007 | Water Research2007，41，15： | 1 |
| 14 | Dynamic behavior and vibration control of a tensegrity structure 显示文摘 | BEL N HADJ ALI SMITH I F C | 2010 | International Journal of Solids and Structures2010，47，9： | 1 |
| 15 | Soil and nutrient losses by water erosion undermono-cropping and legume inter-cropping on sloping land显示文摘 | Ali I Khan F Bhatti A | 2007 | PakistanJournal of Agricultural Research^ Pakistan)2007，20，34： | 1 |
| 16 | The financial accelerator in an estimated New Keynesian model显示文摘 | CHRISTENSEN I ALI DIB | | 0，，01： | 1 |
| 17 | Polysaccharides chiral stationary phases in liquid chromatography 显示文摘 | Ali I Saleem K Hussain I | 2009 | Sep Purif Rev2009，38，： | 1 |
| 18 | Interactions of some Schiff base compounds with mild steel surface in hydrochloric acid solution显示文摘 | Emel Bayol Tijen G i rten Ali G rten A | 2008 | Materials Chemistry and Physics2008，，6： | 1 |
| 19 | Reducing the friction of lubricated nonconformal point contacts by transverse shallow micro- grooves显示文摘 | Ali F K~upka I Hartl M | 2014 | Engineering Tribology2014，，： | 1 |
| 20 | Sequencing ofNOTCH1, GATA5 , TGFBR1 and TGFBR2 genes in familialcases of bicuspid aortic valve 显示文摘 | FOFFA I AIT ALI L PANESI P | 2013 | BMC Med Genet2013，14，： | 1 |
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