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| 1 | Ketamine anesthesia reduces intestinal ischemia/reperfusion injury in rats显示文摘AIM: To investigate the effects of ketamine anesthesia on the motility alterations and tissue injury caused by ischemia/reperfusion in rats. METHODS: Thirty male Wistar rats weighing 200-250 g were used. Ischemia was induced by ob-structing blood flow in 25% of the total small intesti-nal length (ileum) with a vascular clamp for 45 min, after which either 60 min or 24 h of reperfusion was allowed. Rats were either anesthetized with pento-barbital sodium (50 mg/kg) or ketamine (100 mg/kg). Control groups received sham surgery. After 60 min of reperfusion, the intestine was examined for mor-phological alterations, and after 24 h intestinal basic electrical rhythm (BER) frequency was calculated, and intestinal transit determined in all groups. RESULTS: The intestinal mucosa in rats that were anesthetized with ketamine showed moderate altera-tions such as epithelial lifting, while ulceration and hemorrhage was observed in rats that received pento-barbital sodium after 60 min of reperfusion. Quantita-tive analysis of structural damage using the Chiu scaleshowed significantly less injury in rats that received ketamine than in rats that did not (2.35 ± 1.14 vs 4.58 ± 0.50, P < 0.0001). The distance traveled by a mark-er, expressed as percentage of total intestinal length, in rats that received pentobarbital sodium was 20% ± 2% in comparison with 25.9% ± 1.64% in rats that re-ceived ketamine (P = 0.017). BER was not statistically different between groups. CONCLUSION: Our results show that ketamine anesthesia is associated with diminished intestinal injury and abolishes the intestinal transit delay induced by ischemia/reperfusion. | Carlos Rodrigo Cámara Francisco Javier Guzmán Ernesto Alexis Barrera Andrés Jesús Cabello Armando Garcia Nancy Esthela Fernández Eloy Caballero Jesus Ancer | 2008 | World Journal of Gastroenterology2008，14，33： | 5 |
| 2 | Clinical applications of advanced magnetic resonance imaging techniques for arthritis evaluation显示文摘Magnetic resonance imaging(MRI) has allowed a comprehensive evaluation of articular disease, increasing the detection of early cartilage involvement, bone erosions, and edema in soft tissue and bone marrow compared to other imaging techniques. In the era of functional imaging, new advanced MRI sequences are being successfully applied for articular evaluation in cases of inflammatory, infectious, and degenerative arthropathies. Diffusion weighted imaging, new fat suppression techniques such as DIXON, dynamic contrast enhanced-MRI, and specific T2 mapping cartilage sequences allow a better understanding of the physiopathological processes that underlie these different arthropathies. They provide valuable quantitative information that aids in their differentiation and can be used as potential biomarkers of articular disease course and treatment response. | Teodoro Martín Noguerol Antonio Luna Marta Gómez Cabrera Alexie D Riofrio | 2017 | World Journal of Orthopedics2017，8，9： | 2 |
| 3 | Subcutaneous emphysema, pneumomediastinum and pneumoperitoneum after unsuccessful ERCP: a case report 显示文摘 | Alexiou K Sakellaridis T Sikalias N | 2009 | Cases J2009，2，1： | 1 |
| 4 | Differ ential estrogen receptor subtype modulators: assessment of estrogen receptor subtype-binding selectivity and transcription-regulating properties of new cycloalkyl pyrazoles显示文摘 | Alexi X Kasiotis K M Fokialakis N | 2009 | J Steroid Biochem Mol Biol2009，117，45： | 1 |
| 5 | The genetic basis of craniofacial and dental abnormalities显示文摘 | Kouskoura T Fragou N Alexiou M | 2011 | Schweiz Monatsschr Zahn- med2011，121，78： | 1 |
| 6 | The health effects of non-industrial indoor air pollution 显示文摘 | BERNSTEIN J A ALEXIS N BACCHUS H | 2008 | J Allergy Clin Immunol2008，121，3： | 1 |
| 7 | Effect of density on growth rate and production of rainbow trout (Salmo gairdneri) over a full rearing period显示文摘 | Papoutsoglou S E Papaparaskeva-Papoutsoglou E Alexis M N | 1987 | Aquac1987，66，： | 1 |
| 8 | Doctoral education in social work :what we know and what we need to know显示文摘 | Jeane W A Alexis N K | 2009 | Social Work2009，54，1： | 1 |
| 9 | Investigation to determine digestibility coefficients of various raw materials in diets for gilthead sea bream, Sparus auratns L显示文摘 | Nengas I Alexis M N Davies S J | 1995 | Aquaculture Research1995，26，： | 1 |
| 10 | Serum levels of E-selectin, ICAM-1 and VCAM-1 in colorectal cancer patients: correlations with clinicopathological features, patient survival and tumour surgery 显示文摘 | Alexiou D Karayiannakis A J Syrigos K N | 2001 | Eur J Cancer2001，37，18： | 1 |
| 11 | Clinical significance of serum levels of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in gastric cancer patients显示文摘 | Alexiou D Karayiannakis A J Syrigos K N | 2003 | Am J Gastroenterol2003，98，2： | 1 |
| 12 | Cutting edge: A critical role of B and T lymphocyte attenuator in peripheral T cell tolerance induction显示文摘 | Liu X Alexiou M Martin-Orozco N etal | 2009 | J Immunol2009，182，： | 1 |
| 13 | Comparison of wild and cultured gilthead sea bream ( Sparus aurata ) ; Composition,appearance and seasonal variations 显示文摘 | Grigorakis K Alexis M N Taylor K D A | 2002 | International Journal of Food Science and Technology2002，37，： | 1 |
| 14 | Tissue ascorbic acid levels in European sea bass (Dicentrarchus labrax)and gilthead sea bream (Sparus aurata L)fingerlings fed diets containing different forms of ascorbic acid 显示文摘 | Alexis M N NengasI Fountoulaki E | 1999 | Aquaculture1999，179，： | 1 |
| 15 | The health effects of nonin- dustrial indoor air pollution显示文摘 | Bernstein JA Alexis N Bacchus H | 2008 | J Allergy Clin Immunol2008，121，： | 1 |
| 16 | Effects of extrusion and inclusion level of soybean meal on diet digestibility, performance and nutrient u- tilization of gilthead sea bream ( Sparus aurata ) 显示文摘 | VENOU B ALEXIS M N FOUNTOULAKI E | 2006 | Aquaculture2006，261，1： | 1 |
| 17 | Effects of fasting on the meat quality and flat deposition of commercial-size firmed gilthead sea bream SparusaurataL fed different dietary regimes显示文摘 | Grigorakis K Alexis M N | | Aquaculture Nutrition0，1，： | 1 |
| 18 | Development and Integration of Rain Ingestion Effects in Engine Per- formance Simulations 显示文摘 | Roumeliotis I Alexiou A Aretakis N | 2014 | Journal of Engineering for Gas Turbines and Power2014，137，04： | 1 |
| 19 | Serum levels of E-selectin, ICAM-1 and VCAM-1 in colorectal cancer patients :correlations with clinicopathological features, patient survival and tumor surgery 显示文摘 | Alexiou D Karayiannakis A J Syrigos K N | 2001 | Eur J Cancer2001，37，18： | 1 |
| 20 | Inter-species differences in hematocrit to blood viscosity ratio显示文摘 | Nemeth N Alexy T Furka A | 2009 | Biorheology2009，46，2： | 1 |
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