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| 1 | Increased incidence of and microbiologic changes in pyogenic liver abscesses in the Mexican population显示文摘BACKGROUND Pyogenic liver abscess(PLA)is a rare disease with an estimated incidence that varies widely across the globe,being as high as 115.4/100000 habitants in Taiwan and as low as 1.1-1.2/100000 habitants in Europe and Canada.Even though there are multiple microorganisms capable of producing an abscess in the liver,including Entamoeba histolytica,fungi,and viruses,most abscesses are derived from bacterial infections.The epidemiology of PLA in Mexico is currently unknown.AIM To describe the clinical,demographic and microbiologic characteristics of PLA in Mexico.METHODS This is a retrospective study carried out in two centers,and included patients seen between 2006 and 2018 with the diagnosis of pyogenic abscess.We collected demographic,clinical,and microbiological information,treatment,complications,and outcomes.A logistic regression analysis was used to determine the association between different variables and mortality rates.RESULTS A total of 345 patients were included in this study.233(67.5%)had confirmed PLA,133(30%)patients had no positive culture and negative serology and 9(2.5%)had mixed abscesses.The mean age was 50 years(ranging from 16-97 years)and 63%were female.65%of the patients had positive cultures for Extended Spectrum Beta-Lactamases(ESBL)-Escherichia coli and Klebsiella pneumoniae.Cefotaxime was administered in 60%of cases.The most common sources of infection were ascending cholangitis and cholecystitis in 34(10%)and 31(9%),respectively.The median length of hospital stay was 14 d.165 patients underwent percutaneous catheter drainage.The inpatient mortality rate was 63%.Immunocompromised state[OR 3.9,95%CI:1.42-10.46],ESBL-Escherichia coli[OR 6.7,95%CI:2.7-16.2]and Klebsiella pneumoniae[OR 4-8,95%CI:1.6-14.4]predicted inpatient mortality by multivariate analysis.CONCLUSION The prevalence of PLA is increasing in Mexico and has a very high mortality rate.ESBL-Escherichia coli and Klebsiella pneumoniae are the most common microorganisms causing PLA and are independent predictors of inpatient mortality. | Juanita Pérez-Escobar Wagner Ramirez-Quesada Daniel Alejandro Calle-Rodas Luis Alberto Chi-Cervera Nalu Navarro-Alvarez Jorge Aquino-Matus Juan Pablo Ramírez-Hinojosa Carlos Moctezuma-Velázquez Aldo Torre | 2020 | World Journal of Hepatology2020，12，10： | 5 |
| 2 | Piez- oelectric transducers for real-time evaluation of fruit firm- ness 显示文摘 | Enrico macrell Aldo Romani Rudi P Paganelli | 2013 | Sensor and Actuators A: Physical2013，201，： | 1 |
| 3 | Selective determination of aromatic amines in water samples by capillary zone electrophoresis and solid-phase extraction显示文摘 | ALDO C VITTORIO P FLAVIA N SILVANO C CLAUDIO R | 1995 | J Chromatogr:A1995，709，2： | 1 |
| 4 | Placental viral infection sensitizes to endotoxin-induced pre-term labor: a double hit hypothesis 显示文摘 | Cardenas I Mor G Aldo P | 2011 | Am J Reprod Immunol2011，65，： | 1 |
| 5 | Gamma-glutamyltrans- ferase atherosclerosis, and cardiovascular disease: triggering oxidative stress within the plaque 显示文摘 | Michele E Alfonso P Aldo P | 2005 | Cireulation2005，112，7： | 1 |
| 6 | Human atherosclerotic plaques contain gamma-glutamyl transpeptidase enzyme activity显示文摘 | Aldo P Michele E Erri G | 2004 | Circulation2004，109，11： | 1 |
| 7 | Serum and tissue thyroglobulin measurement: clinical application in thyroid disease显示文摘 | Furion P Aldo P | 1999 | Bioch1999，81，： | 1 |
| 8 | Spontaneous and piezoelectric polarization effects on the oput characteristics of AlGaN/GaN heterojunction modulation doped FETs显示文摘 | Fabio Sacconi Aldo Di Carlo P Lugli | 2001 | IEEE Trans Electron Device2001，48，3： | 1 |
| 9 | Alteration of the E-cadherin /β-catenin cell adhesion system is common in pulmonary neuroendocrine tumors and is an independent predictor of lymph node metastasis in atypical carcinoids显示文摘 | Giuseppe P Aldo S Giacomo P | 2005 | Cancer2005，103，6： | 1 |
| 10 | Thyrotropin Receptor Polymorphisms and thyoid diseases 显示文摘 | Aldo P | 2000 | J Clin Endocrinol Metab2000，85，26： | 1 |
| 11 | Activation of TLR3 in the trophoblast is associated with preterm delivery显示文摘 | KOGA K CARDENAS I ALDO P | 2009 | Amer- ican Journal of Reproductive Immunology2009，61，3： | 1 |
| 12 | Human atherosclerotic plaques contain gamma-glutamy transpeptidase enzyme acticity 显示文摘 | Aldo P Michele E Erri G | 2004 | Circulation2004，109，： | 1 |
| 13 | A rapid and sensitive 384 -microtiter wells format chemiluminescent enzyme immunoassay for clenbuterol显示文摘 | ALDO R ANNA C M FRANCESCO P | 2000 | Talanta2000，52，2： | 1 |
| 14 | Phylogeography and population genetic structure of the Talas tuco-tuco (Ctenomys talarum): integrating demographic and habitat histories显示文摘 | Mora Mat?as S Cutrera Ana P Lessa Enrique P Vassallo Aldo I D’Anatro Alejandro Mapelli Fernando J | 2013 | Journal of Mammalogy2013，，2： | 1 |
| 15 | Intermittent androgen deprivation for locally advanced and metastatic prostate cancer; results from a randomised phase 3 study of the South European Uroncological Group显示文摘 | Fernando E C Aldo V B Whelan P | 2009 | Eur Urol2009，55，6： | 1 |
| 16 | Editorial : orbital radiotherapy for Graves' ophthalmopathy显示文摘 | Luigi B Claudio M Aldo P | 2004 | JCEM2004，89，1： | 1 |
| 17 | A rapid and sensitive 384-well microtitre format chemiluminescent enzyme immunoassay for 19- nortestosterone显示文摘 | Aldo R Anna CM Ottavio P | 2003 | Original Research2003，18，： | 1 |
| 18 | Polyurethane resin-based adhesives: curing reaction and properties of cured systems显示文摘 | Giulio M ALDO P FRANCO F | 2005 | International Journal of Adhesion and Adhesives2005，25，1： | 1 |
| 19 | Management of Graves′ ophthalmopathy :Reality and perspectives 显示文摘 | Luigi B Aldo P Claudio M | 2000 | J Endocrine Rev2000，21，： | 1 |
| 20 | Cardiac endocrine function is an essential component of the homeostatic regulation network:physiological and clinical implications显示文摘 | Aldo C Fabio AR Claudio P | 2006 | Am J Physiol Heart Circ Physiol2006，290，： | 1 |
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