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| 1 | Osteoclastic and pleomorphic giant cell tumors of the pancreas:A review of clinical,endoscopic,and pathologic features显示文摘Giant cell tumors of the pancreas come in three varieties-osteoclastic,pleomorphic,and mixed histology.These tumors have distinctive endoscopic,clinical,and cytological features.Giant cell tumors have a controversial histogenesis,with some authors favoring an epithelial origin and others favoring a mesenchymal origin.The true origin of these lesions remains unclear at this time.These are also very rare tumors but proper identification and differentiation from more common pancreatic adenocarcinoma is important.The risk factors of these tumors and the prognosis may be different from those associated with standard pancreatic adenocarcinoma.Recognition of these differences can significantly affect patient care.These lesions have a unique appearance when imaged with endoscopic ultrasound(EUS),and these lesions can be diagnosed via EUS guided Fine Needle Aspiration(FNA).This manuscript will review the endoscopic,clinical,and pathologic features of these tumors. | Jill C Moore Joel S Bentz Kristen Hilden Douglas G Adler | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，1： | 7 |
| 2 | Efficacy of pancreatoscopy for pancreatic duct stones:A systematic review and meta-analysis显示文摘BACKGROUND Pancreatic duct stones can lead to significant abdominal pain for patients.Per oral pancreatoscopy(POP)-guided intracorporal lithotripsy is being increasingly used for the management of main pancreatic duct calculi(PDC)in chronic pancreatitis.POP uses two techniques:Electrohydraulic lithotripsy(EHL)and laser lithotripsy(LL).Data on the safety and efficacy are limited for this procedure.We performed a systematic review and meta-analysis with a primary aim to calculate the pooled technical and clinical success rates of POP.The secondary aim was to assess pooled rates of technical success,clinical success for the two individual techniques,and adverse event rates.AIM To perform a systematic review and meta-analysis of POP,EHL and LL for management of PDC in chronic pancreatitis.METHODS We conducted a comprehensive search of multiple electronic databases and conference proceedings including PubMed,EMBASE,Cochrane,Google Scholar and Web of Science databases(from 1999 to October 2019)to identify studies with patient age greater than 17 and any gender that reported on outcomes of POP,EHL and LL.The primary outcome assessed involved the pooled technical success and clinical success rate of POP.The secondary outcome included the pooled technical success and clinical success rate for EHL and LL.We also assessed the pooled rate of adverse events for POP,EHL and LL including a subgroup analysis for the rate of adverse event subtypes for POP:Hemorrhage,post-endoscopic retrograde cholangiopancreatography pancreatitis(PEP),perforation,abdominal pain,fever and infections.Technical success was defined as the rate of clearing pancreatic duct stones and clinical success as the improvement in pain.Randomeffects model was used for analysis.Heterogeneity between study-specific estimates was calculated using the Cochran Q statistical test and I2 statistics.Publication bias was ascertained,qualitatively by visual inspection of funnel plot and quantitatively by the Egger test.RESULTS A total of 16 studies including 383 patients met the inclusion criteria.The technical success rate of POP was 76.4%(95%CI:65.9-84.5;I2=64%)and clinical success rate was 76.8%(95%CI:65.2-85.4;I2=66%).The technical success rate of EHL was 70.3%(95%CI:57.8-80.3;I2=36%)and clinical success rate of EHL was 66.5%(95%CI:55.2-76.2;I2=19%).The technical success rate of LL was 89.3%(95%CI:70.5-96.7;I2=70%)and clinical success rate of LL was 88.2%(95%CI:66.4-96.6;I2=77%).The incidence of pooled adverse events for POP was 14.9%(95%CI:9.2-23.2;I2=49%),for EHL was 11.2%(95%CI:5.9-20.3;I2=15%)and for LL was 13.1%(95%CI:6.3-25.4;I2=31%).Subgroup analysis of adverse events showed rates of PEP at 7%(95%CI:3.5-13.6;I2=38%),fever at 3.7%(95%CI:2-6.9;I2=0),abdominal pain at 4.7%(95%CI:2.7-7.8;I2=0),perforation at 4.3%(95%CI:2.1-8.4;I2=0),hemorrhage at 3.4%(95%CI:1.7-6.6;I2=0)and no mortality.There was evidence of publication bias based on funnel plot analysis and Egger’s test.CONCLUSION Our study highlights the high technical and clinical success rates for POP,EHL and LL.POP-guided lithotripsy could be a viable option for management of chronic pancreatitis with PDC. | Syed M Saghir Harmeet S Mashiana Babu P Mohan Banreet S Dhindsa Amaninder Dhaliwal Saurabh Chandan Neil Bhogal Ishfaq Bhat Shailender Singh Douglas G Adler | 2020 | World Journal of Gastroenterology2020，26，34： | 5 |
| 3 | Role of pancreatic endoscopic ultrasonography in 2010显示文摘Endoscopic ultrasonography (EUS) was introduced 25 years ago aiming at better visualization of the pancreas compared to transabdominal ultrasonography. This update discusses the current evidence in 2010 concerning the role of EUS in the clinical management of patients with pancreatic disease. Major indications of EUS are:(1) Detection of common bile duct stones (e.g. in acute pancreatitis); (2) Detection of small exo-and endocrine pancreatic tumours; and (3) Performance of fine needle aspiration in pancreatic masses depending on therapeutic consequences. EUS seems to be less useful in cases of chronic pancreatitis and cystic pan-creatic lesions. Moreover the constant improvement of computed tomography has limited the role of EUS in pancreatic cancer staging. On the other hand,new therapeutic options are available due to EUS,such as pancreatic cyst drainage and celiac plexus neurolysis,offering a new field in which new techniques may arise. So the main goal of this review is to determine the exact role of EUS in a number of pancreatic and biliary diseases. | Ioannis S Papanikolaou Pantelis S Karatzas Konstantinos Triantafyllou Andreas Adler | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，10： | 3 |
| 4 | Neuromuscular electrical stimulation and testosterone did not influence heterotopic ossification size after spinal cor injury: A case series显示文摘Neuromuscular electrical stimulation(NMES) and testosterone replacement therapy(TRT) are effective rehabilitation strategies to attenuate muscle atrophy and evoke hypertrophy in persons with spinal cord injury(SCI). However both interventions might increase heterotopic ossification(HO) size in SCI patients. We present the results of two men with chronic traumatic motor complete SCI who also had pre-existing HO and participated in a study investigating the effects of TRT or TRT plus NMES resistance training(RT) on body composition. The 49-year-old male, Subject A, has unilateral HO in his right thigh. The 31-year-old male, Subject B, has bilateral HO in both thighs. Both participants wore transdermal testosterone patches(4-6 mg/d) daily for 16 wk. Subject A also underwent progressive NMES-RT twice weekly for 16 wk. Magnetic resonance imaging scans were acquired prior to and post intervention. Cross-sectional areas(CSA) of thewhole thigh and knee extensor skeletal muscles, femoral bone, and HO were measured. In Subject A(NMES-RT + TRT), the whole thigh skeletal muscle CSA increased by 10%, the knee extensor CSA increased by 17%, and the HO + femoral bone CSA did not change. In Subject B(TRT), the whole thigh skeletal muscle CSA increased by 13% in the right thigh and 6% in the left thigh. The knee extensor CSA increased by 7% in the right thigh and did not change in the left thigh. The femoral bone and HO CSAs in both thighs did not change. Both the TRT and NMES-RT + TRT protocols evoked muscle hypertrophy without stimulating the growth of preexisting HO. | Pamela D Moore Ashraf S Gorgey Rodney C Wade Refka E Khalil Timothy D Lavis Rehan Khan Robert A Adler | 2016 | World Journal of Clinical Cases2016，4，7： | 3 |
| 5 | Social capital:prospects for a new concept显示文摘 | ADLER P S KWON S W | 2002 | The Academy of Management Review2002，27，1： | 1 |
| 6 | Social Capital: Prospects for a New Concept 显示文摘 | Adler P Kwon S | 2002 | Acaderay of Managonent Review2002，，27： | 1 |
| 7 | Accuracy of a novel automatic atrial capture threshold algorithm显示文摘 | Adler S 2nd Schaerf R Quan KJ | 2003 | PACE2003，26，： | 1 |
| 8 | Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease显示文摘 | Vasa M Fichtlscherer S Adler K | 2001 | Circulation2001，103，24： | 1 |
| 9 | Strategic management of technical functions 显示文摘 | Adler P S McDonald D W MacDonald F | 1992 | Sloan Management Review1992，33，2： | 1 |
| 10 | Prevention of chronic fibrillation by pacing in the region of bachmann's bundle:Results of a multicenter randomized trial显示文摘 | Bailin SJ Adler S Giudici M | 2001 | J Cardivasc Electrophys2001，12，8： | 1 |
| 11 | Flexibility versus efficiency?A case study of model changeovers in the Toyota production system显示文摘 | ADLER P S GOLDOFTAS B LEVINE D I | 1999 | Organization Science1999，10，1： | 1 |
| 12 | Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B显示文摘 | Wahl C Liptay S Adler G | | 0，，： | 1 |
| 13 | Efficacy and safety of oral tolvaptan therapy in patients with the syndrome of inappropriate antidiuretic hormone secretion显示文摘 | Verbalis JG Adler S Schrier RW | | 0，，05： | 1 |
| 14 | The calcimimetic AMG 073 as a potential treatment for secondary hyperparathyroidism of end-stage renal disease显示文摘 | Fuarles LD Sherrard DJ Adler S | 2005 | Am J Soc Nephrol2005，14，3： | 1 |
| 15 | Familial trans mission ofrisk factors in the first degree relatives of schizophrenic people显示文摘 | Waldo MC Adler LE Leonard S | 2000 | BiolPsychiatry2000，47，3： | 1 |
| 16 | The role of macrophages in the protection of mice against leptospirosis: in vitro and in vlvo studies 显示文摘 | Tu V Adler B Faine S | 1982 | Pathology1982，14，4： | 1 |
| 17 | Potential of cervical electrosurgical excision procedure for diagnosis and treatment of cervical intraepithelial neoplasia显示文摘 | Herzoh TJ Williams S Adler LM | 1995 | Gynecol Oncol1995，，3： | 1 |
| 18 | Prediotors of the progression of renal disease in the Modification of Diet in Renal Disease Study显示文摘 | Hunsicker LG Adler S Caggiula A | 1997 | Kidney Int1997，51，6： | 1 |
| 19 | Patterns of vascular and anatomical response after rotator cuff repair显示文摘 | Fealy S Adler RS Drakos MC et at | 2006 | Am J Sports Med2006，34，1： | 1 |
| 20 | Possible participation of nitric oxide in the increase of norepinephrine release caused by angiotensin peptides in rat atria显示文摘 | HIRONACCI M M LOVENZO P S ADLER GRASCHINSKY E | 1997 | Hypertension1997，29，6： | 1 |
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