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| 1 | AHA/ASA关于卒中和短暂性脑缺血发作患者卒中预防推荐的更新显示文摘在卒中和短暂性脑缺血发作(transient ischemic attack,TIA)患者卒中预防推荐发表以后,美国心脏协会和美国卒中协会(American Heart Association/American Stroke Association,AHA/ASA)著述委员会对最近的一些试验结果进行了回顾。本文的目的是对这些新资料做简要回顾、更新某些推荐意见并说明进行这些修改的理由。在2个领域已发表了一些新的重要临床试验结果:(1)在非心源性栓塞所致缺血性卒中或TIA患者卒中二级预防中具体抗血小板药的应用;(2)他汀类药物在预防卒中复发中的应用。 | Robert J. Adams Greg Albers Mark J. Alberts Oscar Benavente Karen Furie Larry B. Goldstein Philip Gorelick Jonathan Halperin Robert Harbaugh S. Claiborne Johnston Irene Katzan Margaret Kelly-Hayes Edgar J. Kenton Michael Marks Ralph L. Sacco Lee H. Schwamm 赵洪芹 李海峰 (译) | 2008 | 国际脑血管病杂志2008,16,4: | 123 |
| 2 | 高技术产业技术投入和生产率增长之间关系的研究显示文摘本研究通过一个基于内生增长理论的生产函数模型分析了中国高技术产业行业部门水平上各类技术投入和生产率变动之间的关系。文章使用永续盘存法估算了资本存量和R&D存量,估计了R&D存量和其他知识存量的产出弹性系数,结果显示,当考虑各类技术投入的单独作用时,R&D与国内购入技术的作用比较显著,而当考虑各类技术的交互影响时,R&D与从国外引进技术的合作对生产率的作用非常显著,反映了它们之间的互补关系,即R&D具有提高进口技术吸收能力的作用。 | 王玲 Adam Szirmai | 2008 | 经济学(季刊)2008,7,2: | 91 |
| 3 | 卒中或短暂性脑缺血发作患者的卒中预防指南 美国心脏协会/美国卒中协会为医疗卫生专业人员制定的指南显示文摘本指南旨在为缺血性卒中或短暂性脑缺血发作存活患者的卒中预防提供全面和及时的循证推荐,包括危险因素的控制、动脉粥样硬化性疾病的于预、心源性栓塞的抗栓治疗以及非心源性栓塞性卒中的抗血小板治疗。另外,还对其他许多特殊情况下的复发性卒中预防提供了推荐意见,包括动脉夹层分离、卯圆孔未闭、高同型半胱氨酸血症、高凝状态、镰状细胞病、脑静脉窦血栓形成、女性卒中(尤其是与妊娠和绝经后雌激素替代治疗相关性卒中)、脑出血后抗凝药的使用等,以及实施本指南及其在高危人群中应用的特定方法。 | Karen L. Furie Scott E. Kasner Robert J. Adams Gregory W. Albers Ruth L. Bush Susan C. Fagan Jonathan L. Halperin S. Claiborne Johnston Irene Katzan Walter N. Kernan Pamela H. Mitchell Bruce Ovbiagele Yuko Y. Palesch Ralph L. Sacco Lee H. Schwamm Sylvia Wassertheil-Smoller Tanya N. Turan Deidre Wentworth 李海峰(译) 刘涛(译) 杨潘(译) 王鹏(译) | 2011 | 国际脑血管病杂志2011,19,1: | 391 |
| 4 | 急性缺血性卒中患者早期处理指南:美国心脏协会/美国卒中协会对医疗专业人员的指南(续前)显示文摘7静脉溶栓
7.1静脉rtPA
急性卒中的静脉溶栓治疗现已得到普遍接受。美国FDA于1996年批准静脉应用rtPA,部分基于NINDSrtPA卒中试验结果。 | Edward C. Jauch Jeffrey L. Saver Harold P. Adams Askiel Bruno J.J. (Buddy) Connors Bart M. Demaerschalk Pooja Khatri Paul W. McMullan Adnan I. Qureshi Kenneth Rosenfield Phillip A. Scott Debbie R. Summers David Z. Wang Max Wintermark Howard Yonas 李海峰(译) 岳耀先(译) 王琦(译) 张贤军(译) 丁晓君(译) | 2013 | 国际脑血管病杂志2013,21,8: | 975 |
| 5 | 婴幼儿卒中的处理:来自美国心脏协会卒中委员会和青少年心血管病委员会专门写作组的科学声明显示文摘目的:本声明旨在回顾有关儿童卒中的文献,为最佳的诊断和治疗提供推荐意见,供负责诊断和治疗婴儿、儿童和青少年脑血管病的医生使用。方法:写作组成员由美国心脏协会卒中委员会科学声明监督委员会任命,由多个不同领域的专家组成。应用美国心脏协会卒中委员会的证据分级标准对每条推荐意见进行分级。在经过小组成员审查后,草稿由4位同行评议专家和卒中委员会指导委员会成员审阅,并由美国心脏协会科学咨询和协调委员会批准。我们预计该声明需在4年内进行更新。结果:为镰状细胞病、烟雾病、颈一脑动脉夹层分离和心源性栓塞引起的缺血性卒中的预防提供循证推荐,同时为出血性卒中的评价和处理提供推荐意见。提出儿童使用肝素和华法林的剂量方案。另外,还为围产期卒中和儿童脑静脉窦血栓形成的评价和处理提供推荐。 | E.Steve Roach(著) Meredith R. Golomb(著) Robert Adams(著) Jose Biller(著) Stephen Daniels(著) Gabrielle deVeber(著) Donna Ferriero(著) Blaise V. Jones(著) Fenella J. Kirkham(著) R. Michael Scott(著) Edward R. Smith(著) 刘丽芳(译) 王胜男(译) 王伟(译) 林镇洲(译) 朱佳佳(译) 潘速跃(译) | 2008 | 国际脑血管病杂志2008,16,11: | 60 |
| 6 | 中国大陆肺炎发病率与死亡率:1985-2008年中英文文献的系统分析显示文摘目的肺炎是全球传染性疾病最主要的死因之一,但中国的肺炎疾病负担还知之甚少,因为很多数据资料都是以非英文文献的形式发表的。方法系统回顾了中国大陆关于肺炎发病率与死亡率的中文和英文文献,这些研究都是具有第一手数据的研究,1985-2008年有37篇论文符合纳入标准。结果各项研究的质量差异较大。5岁以下儿童肺炎发病率为(0.06~0.27)次/人年,肺炎死亡率为184/10万~1 223/10万人口。肺炎的发病率与死亡率随着时间稳定不变或者呈下降趋势,且农村高于城市。结论肺炎仍然是中国儿童的主要公共卫生问题之一。肺炎发病率与死亡率估计的变化差异大。继续降低发病率与死亡率需要可靠的监测数据和新的预防措施的实施,特别是在农村等高发地区。 | 官旭华 Benjamin J Silk Wenkai Li Aaron T. Fleishchauer 邢学森 蒋晓清 余宏杰 Sonja J. Olsen Adam L. Cohen | 2011 | 公共卫生与预防医学2011,22,1: | 54 |
| 7 | 湿粘水稻土深松过程离散元分析显示文摘湿粘水稻土的深耕松对作业机具设计与作业参数的要求不同于旱作制,为探究水稻土条件下土壤深松扰动过程及其内在相互作用机理,本文结合田间实测土壤物理参数,借助离散元EDEM软件,建立适用于粘性水稻土的深松耕作离散元模型。利用粘性水稻土模型对水稻土的机械深松耕作过程进行离散元模拟仿真,并结合田间试验结果对机具耕作阻力、土壤宏观扰动进行对比验证,进一步从仿真的角度揭示深松土壤扰动的微观过程、土壤失效破碎的微观机理。结果表明,该模型下深松耕作阻力平均误差为6.63%,土壤扰动的起垄宽度平均误差为4.39%,起垄高度平均误差为19.22%;DEM仿真对土壤的微观扰动过程分析进一步论证了宏观试验测试结果及假说的正确,并且能够从土颗粒接触力学层面表达土壤扰动的边界生成、土体内部破碎等过程;结合DEM仿真角度提出的反映土体破碎程度指标——断裂系数,与传统试验的指标参数碎土系数对比两者误差为3.46%,该指标更有利于对土壤破碎过程微观机理的表达。 | 丁启朔 任骏 BELAL Eisa Adam 赵吉坤 葛双洋 李杨 | 2017 | 农业机械学报2017,48,3: | 57 |
| 8 | 土壤微生物多样性研究的新方法显示文摘传统的分离培养和鉴定土壤微生物方法所具有的困难性和局限性 ,是造成难以深入了解土壤微生物生态学特性和多样性组成方面的主要障碍。本文运用分子生物学技术 ,以澳大利亚两种主要森林类型的土壤微生物多样性研究为实例 ,介绍了从土壤中直接提取土壤微生物DNA的方法以及末端限制性酶切片段长度多态性 (T RFLP)分析的基本原理和方法。作者认为 ,用该方法提取的土壤真菌DNA的纯度高 ,完全适合PCR扩增和T RFLP分析的要求。T | 马万里 Josquin Tibbits Mark Adams | 2004 | 土壤学报2004,41,1: | 59 |
| 9 | 他汀、高密度脂蛋白胆固醇与冠状动脉粥样硬化消退显示文摘背景:他汀类药物可以降低低密度脂蛋白胆固醇(low—density lipoprotein cholesterol,LDL—C)水平并减缓冠状动脉粥样硬化的进展。然而,对于他汀类药物所致高密度脂蛋白胆固醇(high—density lipoprotein cholesterol,HDL—C)变化与疾病进展的关系,目前仍无相关数据描述。目的:了解LDL—C和HDL—C水平变化与动脉粥样硬化的相互关系。设计、地点及患者:对4项前瞻性随机试验(1999~2005年在美国、北美、欧洲和澳大利亚进行)的原始数据进行事后分析。其中1455例经血管造影证实的冠心病患者在接受他汀治疗(18个月或24个月)时进行了系列血管内超声扫描。所有超声分析均在相同的核心实验室中进行。主要观测指标:脂蛋白水平变化与冠状动脉粥样斑块体积的相互关系。结果:他汀治疗期间,LDL—C平均(SD)水平从124.0(38.3)mg,/dL(3.2[0.99]mmol/L)降至87.5(28.8)mg,/dL(2.3[0.75]mmol/L)(下降23.5%;P〈0.001),HDL—C水平从42.5(11.0)mg/dL(1.1[0.28]mmol/L)升至45.1(11.4)mg/dL(1.2[0.29]mmol/L)(上升7.5%;P〈0.001)。LDL—C与HDL—C比值从平均(SD)3.0(1.1)降至2.1(0.9)(下降26.7%;P〈0.001)。这些变化同时伴随平均(SD)百分粥样斑块体积的增加(从39.7%[9.8%]增至40.1%[9.7%])(增加0.5%[3.9%];P=0.001)以及平均(SD)总粥样斑块体积的减小(2.4[23.6]mm^3;P〈0.001)。在单变量分析中,LDL—C、总胆固醇、非HDL胆固醇、载脂蛋白B以及载脂蛋白B与载脂蛋白A-1比值平均水平和治疗引起的变化与动脉粥样硬化进展速率显著相关,而治疗所致HDL—C变化则与动脉粥样斑块体积负相关。在多变量分析中,平均LDL—C水平(β系数,0.11[95%可信区间,0.07~0.15])以及HDL—C升高(β系数,-0.26[95%可信区间,-0.41--0.10])依然为动脉粥样硬化消退的独立预测因子。动脉硬化显著消退(动脉粥样斑块体积减少≥5%)见于治疗期间LDL—C水平低于均值(87.5mg/dL)和HDL—C升高百分比大于均值(7.5%;P〈0.001)的患者。临床事件的发生未见显著差异。结论:在LDL—C显著降低以及HDL上升〉7.5%时,他汀治疗与冠状动脉粥样硬化消退相关。这些结果提示他汀治疗的获益源自致动脉粥样硬化脂蛋白的降低以及HDL.C的升高。尽管血脂水平的这些变化与动脉粥样硬化消退相关,但是后者是否可以转化为临床事件的显著减少,并改善临床预后仍有待进一步研究确定。 | Stephen J. Nicholls, MBBS, PhD E. Murat Tuzcu, MD IIke Sipahi, MD Adam W. Grasso, MD Paul Schoenhagen, MD Tingfei Hu, MS Kathy Wolski, MPH Tim Crowe, BS Milind Y. Desai, MD Stanley L. Hazen, MD, PhD Samir R. Kapadia, MD Steven E. Nissen, MD 李呈亿(译) | 2007 | 美国医学会杂志(中文版)2007,26,3: | 48 |
| 10 | Apoptosis and DNA damage in human spermatozoa显示文摘DNA 损坏经常在 subfertile 男性的精子被遇到并且包括损害授精与不利临床的结果的一个范围被相关,破坏 preimplantation 胚胎的开发,流产的增加的率和在子孙的疾病的提高的风险。在人的精子的 DNA 破碎的病原学密切与氧化的底的外观被相关使内收并且损害精子形式的证据。我们假设那个氧化压力阻碍精子形式,与糟糕改变的染色质导致精子的产生。这些有缺点的房间有一个趋势默认到线粒体与活动性损失, caspase 激活, phosphatidylserine exteriorization 和免费激进的产生的激活联系的一条 apoptotic 小径。后者导致类脂化合物 peroxidation 和氧化 DNA 损坏,它然后导致 DNA 破碎和房间死亡。精子的物理体系结构阻止从获得存取到原子 DNA 并且导致它的破碎由于这 apoptotic 进程激活的任何核酸酶。是为这个原因在人的精子遇到的 DNA 损坏的一个多数似乎氧化。给氧化应力似乎在 DNA 损坏的病原学有的重要角色,应该为在这个条件的处理的抗氧化剂有一个重要角色。如果在精子的氧化 DNA 损坏正在提供全身的氧化应力的敏感读出,这些调查结果的含意能在我们试着作为一篇序言在精子最小化 DNA 损坏到帮助概念治疗的立即的目标以外拉长。 | R John Aitken Adam J Koppers | 2011 | Asian Journal of Andrology2011,13,1: | 46 |
| 11 | Pathophysiological and clinical aspects of gastric hyperplastic polyps显示文摘Gastric polyps become a major clinical problem because of high prevalence and tendency to malignant transformation of some of them. The development of gastric hyperplastic polyps results from excessive proliferation of foveolar cells accompanied by their increased exfoliation, and they are macroscopically indistinguishable from other polyps with lower or higher malignant potential. Panendoscopy allows detection and differentiation of gastric polyps, usually after obtaining histopathological biopsy specimens. Unremoved gastric hyperplastic polyps may enlarge and sometimes spontaneously undergo a sequential progression to cancer. For this reason, gastric hyperplastic polyps larger than 5 mm in size should be removed in one piece. After excision of polyps with atypical focal lesion, endoscopic surveillance is suggested depending on histopathological diagnosis and possibility of confirming the completeness of endoscopic resection. Because of the risk of cancer development also in gastric mucosa outside the polyp, neighboring fragments of gastric mucosa should undergo microscopic investigations. This procedure allows for identification of patients who can benefit most from oncological endoscopic surveillance. If Helicobacter pylori(H. pylori) infection of the gastric mucosa is confirmed, treatment strategies should include eradication of bacteria, which may prevent progression of intestinal metaplasia. The efficacy of H. pylori eradication should be checked 3-6 mo later. | Adam Roman Markowski Agnieszka Markowska Katarzyna Guzinska-Ustymowicz | 2016 | World Journal of Gastroenterology2016,22,40: | 42 |
| 12 | Trace element characteristics of partial melts produced by melting of metabasalts at high pressures: Constraints on the formation condition of adakitic melts显示文摘Experiments were conducted on a natural basalt (with 5 wt.% added H2O) at 1.0―2.5 GPa and 900―1100℃. Experimental products include partial melts (quenched glasses) + residual mineral assemblages of amphibolite or eclogite. Electron microprobe and LAM-ICP-MS were used to determine major and trace element compositions of these quenched melts, respectively. Major ele- ment compositions of all the melts are tonalitic- trondhjemitic, similar to adakite. Their trace element characteristics are controlled by coexisting residual minerals. Signatures of adakite such as high Sr/Y, low HREE and negative Nb-Ta anomaly, etc. are present only in the melts coexisting with residual assemblages containing rutile and garnet (rutile-bearing eclogite or rutile-bearing amphibole-eclogite). Garnet leads to HREE depletion in melts, whereas rutile controls Nb and Ta partitioning during the partial melting and causes negative Nb-Ta anomaly in melts. Therefore, in addition to garnet, rutile is also a necessary residual phase during the generation of adakite or TTG magmas to account for the negative Nb-Ta anomaly of the magmas. The depth for the generation of adakite/TTG magmas via melting of metabasalt must be more than about 50 km based on the approximate 1.5 GPa mini- mum-pressure for rutile stability in the partial melting field of hydrous basalt. | J. Adam T.H. Green | 2006 | Science China Earth Sciences2006,49,9: | 33 |
| 13 | Prevalence of HPV Infection And Cervical Intraepithelial Neoplasia And Attitudes towards HPV Vaccination among Chinese Women Aged 18-25 in Jiangsu Province显示文摘Objective:Few data are available on the epidemiology of HPV and cervical cancer among Chinese women younger than 25 years old.This study aimed to estimate the HPV infection rate and the prevalence of cervical intraepithelial neoplasia(CIN) in women aged 18-25,as well as their knowledge of and attitudes towards HPV vaccination.Methods:A population-based cervical cancer screening study was conducted on women aged 18-25 in Jiangsu province in 2008.Participants provided socio-demographic,reproductive and behavioral information and completed a survey about their knowledge of and attitudes towards HPV vaccination.Women then underwent a gynecologic exam to provide two cervical exfoliated cell samples for high risk HPV DNA testing and liquid-based cytology(LBC) as well as visual inspection with acetic acid(VIA).Women testing positive for any test were referred to colposcopy and biopsy.The gold standard for diagnosis of cervical lesions was directed or random biopsies.Results:Within the sample of 316 women,3.4% of them were diagnosed with CIN grade 2 or worse lesions and 17.1% were found to be positive for HPV DNA.Among these young women,extra-marital sexual behavior of them(OR=2.0,95%CI:1.1-3.8) or their husbands(OR=2.6,95%:1.4-4.7) were associated with an increased risk of HPV positivity.Although overall HPV awareness was low,after a brief educational intervention,98.4% reported they would electively receive HPV vaccination and would also recommend that their daughters be vaccinated.However,most urban and rural women reported their ideal maximum out-of-pocket contribution for HPV vaccination to be less than 500 RMB and 50-100 RMB,respectively.Conclusion:Our study indicates cervical disease burden is relatively high among sampled Chinese women aged 18-25.Appropriate educational interventions for female adolescents and strategies to subsidize vaccine costs are definitely needed to ensure the effectiveness of vaccination campaigns in China. | Shang-ying Hu Ying Hong Fang-hui Zhao Adam K. Lewkowitz Feng Chen Wen-hua Zhang O.in-jing Pan Xun Zhang Cindy Fei Hui Li You-lin Qiao | 2011 | Chinese Journal of Cancer Research2011,23,1: | 31 |
| 14 | Weaning stress and gastrointestinal barrier development:Implications for lifelong gut health in pigs显示文摘The gastrointestinal(GI) barrier serves a critical role in survival and overall health of animals and humans. Several layers of barrier defense mechanisms are provided by the epithelial, immune and enteric nervous systems. Together they act in concert to control normal gut functions(e.g., digestion,absorption, secretion, immunity, etc.) whereas at the same time provide a barrier from the hostile conditions in the luminal environment. Breakdown of these critical GI functions is a central pathophysiological mechanism in the most serious GI disorders in pigs. This review will focus on the development and functional properties of the GI barrier in pigs and how common early life production stressors, such as weaning, can alter immediate and long-term barrier function and disease susceptibility.Specific stress-related pathophysiological mechanisms responsible for driving GI barrier dysfunction induced by weaning and the implications to animal health and performance will be discussed. | Adam J.Moeser Calvin S.Pohl Mrigendra Rajput | 2017 | Animal Nutrition2017,,4: | 33 |
| 15 | 复杂场源形态的海洋可控源电磁三维正演显示文摘在使用电偶极发射源的可控源电磁法(CSEM)勘探中,发射源的方位、长度、形状等对观测数据有重要的影响,然而现有的大部分三维数值模拟方法没有全面地将这些因素考虑进来,很多都只能应对非常简单的场源形态,例如单一方位的点电偶极子,这有可能显著降低模拟结果的准确性.本文实现了基于交错网格有限体积(FV)离散的海洋CSEM三维正演算法,能够模拟形态相对复杂的场源,包括任意方位的有限长直导线和弯曲导线发射源.该算法使用一次场/二次场方法,只需对二次场使用FV法求解,避免了场源的奇异性问题;一次场的计算为一维正演问题,使用准解析法求解,并且只要在计算一次场时考虑复杂的场源形态便可以实现同样场源的三维正演.通过与一维理论模型的解析解对比验证了三维程序的准确性,并针对三维理论模型进行了一系列正演测试,初步考察了场源形态对三维正演结果的影响. | 韩波 胡祥云 Adam SCHULTZ 左博新 李建慧 蔡建超 | 2015 | 地球物理学报2015,58,3: | 32 |
| 16 | 基于时序NDVI的露天煤矿区土地损毁与复垦过程特征分析显示文摘露天煤矿区是人类活动强扰动地区之一。该文以阿巴拉契亚煤田区韦恩县为研究区域,应用遥感时序分析法分析了像元尺度的土地损毁和复垦过程特征。得出结论:1984-2010年间,韦兹县露天开采扰动区域占采矿权范围的45.80%,其中植被恢复区域占开采范围的66.45%,开采时间越早,植被恢复像元比例越高;开采造成的地表无植被覆盖期时长中位数为6 a,均值为7 a;已充分复垦的区域,NDVI值恢复至采前水平的加权平均时长为12 a。基于像元变化轨迹的研究,除揭示土地损毁-复垦过程特征外,能较好地反映空间异质性,可以为土地复垦管理和相关政策决策提供科学依据。 | 李晶 Zipper Carl E. 李松 Donovan Patricia F. Wynne Randolph H. Oliphant Adam J. 夏清 | 2015 | 农业工程学报2015,31,16: | 32 |
| 17 | An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options显示文摘Since the documented observations of Kanner in1943, there has been great debate about the diagnoses, the sub-types, and the diagnostic threshold that relates to what is now known as autism spectrum disorder(ASD).Re?ecting this complicated history, there has been continual re?nement from DSM-III with ‘Infantile Autism' to the current DSM-V diagnosis. The disorder is now widely accepted as a complex, pervasive, heterogeneous condition with multiple etiologies, sub-types, and developmental trajectories. Diagnosis remains based on observation of atypical behaviors, with criteria of persistent de?cits in social communication and restricted and repetitive patterns of behavior. This review provides a broad overview of the history, prevalence, etiology, clinical presentation, and heterogeneity of ASD. Factors contributing to heterogeneity, including genetic variability, comorbidity, and gender are reviewed. We then explore current evidencebased pharmacological and behavioral treatments for ASD and highlight the complexities of conducting clinical trials that evaluate therapeutic ef?cacy in ASD populations.Finally, we discuss the potential of a new wave of research examining objective biomarkers to facilitate the evaluation of sub-typing, diagnosis, and treatment response in ASD. | Anne Masi Marilena M.De Mayo Nicholas Glozier Adam J.Guastella | 2017 | Neuroscience Bulletin2017,33,2: | 33 |
| 18 | 缺血性卒中的一级预防——美国心脏协会/美国卒中协会卒中委员会指南 动脉粥样硬化性周围血管病跨学科工作组、心血管护理委员会、临床心脏病学委员会、营养、体力活动和代谢委员会以及医疗质量和转归研究跨学科工作组共同倡导显示文摘背景和目的本指南提供有关各种确定和潜在的卒中危险因素证据的概述,并提供降低卒中风险的推荐。方法写作组成员由委员会主席根据每位作者先前在相关课题领域中的工作提名,并经美国心脏协会(AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾(涵盖时间段为2001年最后一次回顾发表到2005年1月),参考先前已发表的指南、个人文件和专家意见来概括现有的证据,指明现有知识的差距;如果合适,则根据标准的AHA标准做出简明的推荐。写作组全体成员在撰写过程中均有很多机会对推荐进行评论并认可这份声明的最终版本。在AHA科学咨询与协调委员会批准之前,本指南已进行过广泛的同行评议。结果对评价个体首次卒中风险的流程图进行评估。根据干预的可能性(不可干预、可干预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预的危险因素包括年龄、性别、出生体重低、人种/种族和遗传因素。证据充分的可干预危险因素包括高血压、主动或被动吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、缺乏体力活动、肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、脂蛋白相关的磷脂酶升高、高凝状态、炎症和感染。对应用阿司匹林进行卒中一级预防的资料进行回顾。结论有大量证据可以用于确定增加首次卒中风险的各种特殊因素和提供降低这种风险的策略。 | Larry B. Goldstein Robert Adams Mark J. Alberts Lawrence J. Appel Lawrence M. Brass Cheryl D. Bushnell Antonio Culebras Thomas J. DeGraba Philip B. Gorelick John R. Guyton Robert G. Hart George Howard Margaret Kelly-Hayes J.V. (Ian) Nixon Ralph L. Sacco 苏克江 高宗恩 | 2006 | 国际脑血管病杂志2006,14,8: | 28 |
| 19 | Dielectric metasurfaces for complete and independent control of the optical amplitude and phase显示文摘Metasurfaces are optically thin metamaterials that promise complete control of the wavefront of light but are primarily used to control only the phase of light.Here,we present an approach,simple in concept and in practice,that uses meta-atoms with a varying degree of form birefringence and rotation angles to create high-efficiency dielectric metasurfaces that control both the optical amplitude and phase at one or two frequencies.This opens up applications in computer-generated holography,allowing faithful reproduction of both the phase and amplitude of a target holographic scene without the iterative algorithms required in phase-only holography.We demonstrate all-dielectric metasurface holograms with independent and complete control of the amplitude and phase at up to two optical frequencies simultaneously to generate two-and three-dimensional holographic objects.We show that phaseamplitude metasurfaces enable a few features not attainable in phase-only holography;these include creating artifactfree two-dimensional holographic images,encoding phase and amplitude profiles separately at the object plane,encoding intensity profiles at the metasurface and object planes separately,and controlling the surface textures of three-dimensional holographic objects. | Adam C.Overvig Sajan Shrestha Stephanie C.Malek Ming Lu Aaron Stein Changxi Zheng Nanfang Yu | 2019 | Light(Science & Applications)2019,8,1: | 27 |
| 20 | 湘西沃溪钨锑金矿床辉锑矿脉矿物学特征及其矿床成因指示显示文摘辉锑矿脉为沃溪钨锑金矿床最具工业价值的矿石类型。本文报道了近期对该型矿石的主要矿石矿物如自然金、自然锑、辉锑矿、白钨矿、黑钨矿等的观察研究和电子探针分析结果。分析了矿石矿物微量化学成分特征及其所揭示的矿床成因信息。研究表明 ,矿床成矿应与区域构造 岩浆作用有成因联系。从而建立了该矿床新的成矿机理模式。 | 彭渤 陈广浩 Adam Piestrzynski | 2003 | 矿物学报2003,23,1: | 28 |