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| 1 | 保护动机理论在个体行为改变中的应用和发展显示文摘 | 王芸 肖霞 郑频频 Abu Abdullah 傅华 | 2009 | 中国健康教育2009，25，11： | 38 |
| 2 | Rubber band ligation for 750 cases of symptomatic hemorrhoids out of 2200 cases显示文摘AIM: To study the results for the treatment of symptomatic hemorrhoids using rubber band ligation (RBL) method. METHODS: A retrospective study for 750 patients who came to the colorectal unit from June, 1998 to September, 2006, data was retrieved from archived fi les. RBL was performed using the Mc Gown applicator on an outpatient basis. The patients were asked to return to out-patient clinic for follow up at 2 wk, 1 mo, 6 mo and through telephone call every 6 mo for 2 years). RESULTS: After RBL, 696 patients (92.8%) were cured with no difference in outcome for second or third degree hemorrhoids (P = 0.31). Symptomatic recurrence was detected in 11.04% after 2 years. A total of 52 patients (6.93%) had 77 complications from RBL which required no hospitalization. Complications were pain, rectal bleeding and vaso-vagal symptoms(4.13%, 4.13% and 1.33% of patients, respectively). At 1 mo there were a significant improvement in mean SF-36 scores over baseline in five items, while after 2 years there were improvement in all items over baseline, but not significant. No significant manometeric changes after band ligation. CONCLUSION: RBL is a simple, safe and effective method for treating symptomatic second and third degree hemorrhoids as an out patient procedure with signifi cant improvement in quality of life. RBL doesn't alter ano-rectal functions. | Ayman M El Nakeeb Amir A Fikry Waleed H Omar Elyamani M Fouda Tito A El Metwally Hosam E Ghazy Sabry A Badr Mohmed Y Abu Elkhar Salih M Elawady Hisham H Abd Elmoniam Waiel W Khafagy Mosaad M Morshed Ramadan E El Lithy Mohamed E Farid | 2008 | World Journal of Gastroenterology2008，14，42： | 24 |
| 3 | Vitamin D improves viral response in hepatitis C genotype 2-3 nave patients显示文摘AIM: To examine whether vitamin D improved viral response and predicted treatment outcome in patients with hepatitis C virus (HCV) genotype 2-3. METHODS: Fifty patients with chronic HCV genotype 2-3 were randomized consecutively into two groups: Treatment group [20 subjects, age 48 ± 14 years, body mass index (BMI) 30 ± 6, 65% male], who received 180 μg pegylated α-interferon-2a plus oral ribavirin 800 mg/d (Peg/RBV), together with oral vitamin D3 (Vitamidyne D drops; 2000 IU/d, 10 drops/d, normal serum level > 32 ng/mL) for 24 wk; and control group (30 subjects, age 45 ± 10 years, BMI 26 ± 3, 60% male), who received identical therapy without vitamin D. HCV RNA was assessed by reverse transcription polymerase chain reaction. Undetectable HCV RNA at 4, 12 and 24 wk after treatment was considered as rapid virological response, complete early virological response, and sustained virological response (SVR), respectively. Biomarkers of in? ammation were measured. RESULTS: The treatment group with vitamin D hadhigher BMI (30 ± 6 vs 26 ± 3, P < 0.02), and high viral load (> 400 000 IU/mL, 65% vs 40%, P < 0.01) than controls. Ninety-fi ve percent of treated patients were HCV RNA negative at week 4 and 12. At 24 wk after treatment (SVR), 19/20 (95%) treated patients and 23/30 (77%) controls were HCV RNA negative (P < 0.001). Baseline serum vitamin D levels were lower at baseline (20 ± 8 ng/mL) and increased after 12 wk vitamin D treatment, to a mean level of (34 ± 11 ng/ mL). Logistic regression analysis identifi ed vitamin D supplement [odds ratio (OR) 3.0, 95% CI 2.0-4.9, P < 0.001], serum vitamin D levels (< 15 or > 15 ng/mL, OR 2.2, P < 0.01), and BMI (< 30 or > 30, OR 2.6, P < 0.01) as independent predictors of viral response. Adverse events were mild and typical of Peg/RBV. CONCLUSION: Low vitamin D levels predicts negative treatment outcome, and adding vitamin D to conventional Peg/RBV therapy for patients with HCV genotype 2-3 signifi cantly improves viral response. | Assy Nimer Abu Mouch | 2012 | World Journal of Gastroenterology2012，18，8： | 24 |
| 4 | 外语能力磨蚀的性别差异初探显示文摘对300余名大学生进行了英语阅读和听力测试,并从中随机抽取男女生各50名进行了写作测试,得出如下结论:(1)外语磨蚀程度存在明显的性别差异;(2)男女生在深度阅读、短对话听力以及段落听力方面的磨蚀差异不显著;(3)女生在快速阅读能力方面的磨蚀程度明显超过男生;(4)女生写作能力在切题性、连贯性以及清楚性方面的磨蚀程度显著大于男生,而在语言的正确性方面的磨蚀没有明显超过男生。 | 于中根 Chan Swee Heng Ain Nadzimah Bt Abdullah Bahaman bin Abu Samah Yap Ngee Thai | 2010 | 南京邮电大学学报(社会科学版)2010，12，2： | 19 |
| 5 | A survey on trust based detection and isolation of malicious nodes in ad-hoc and sensor networks显示文摘 | Adnan AHMED Kamalrulnizam ABU BAKAR Muhammad Ibrahim CHANNA Khalid HASEEB Abdul Waheed KHAN | 2015 | Frontiers of Computer Science2015，9，2： | 15 |
| 6 | Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases显示文摘AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary tumors.METHODS This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.CONCLUSION Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%. | ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab | 2017 | World Journal of Gastroenterology2017，23，38： | 15 |
| 7 | Normal vitamin D levels are associated with spontaneous hepatitis B surface antigen seroclearance显示文摘AIM: To investigate a possible association between serum vitamin D levels and spontaneous hepatitis B surface antigen (HBsAg) seroclearance. METHODS: Fifty-three patients diagnosed with chronic inactive hepatitis B and spontaneous HBsAg seroclearance were followed up in two Israeli liver units between 2007 and 2012. This retrospective study reviewed medical charts of all the patients, extracting demographic, serological and vitamin D rates in the serum, as well as medical conditions and current medical therapy. Spontaneous HBsAg seroclearance was defined as the loss of serum HBsAg indefinitely. Vitamin D levels were compared to all patients who underwent spontaneousHBsAg seroclearance.HBsAg seroclearance. RESULTS: Out of the 53 patients who underwent hepatitis B antigen seroclearance, 44 patients (83%) had normal levels of 25-hydroxyvitamin vitamin D compared to 9 patients (17%) who had below normal levels. Multivariate analysis showed that age (>35 years) OR = 1.7 (95%CI: 1.25-2.8, P=0.05), serum vitamin D levels (>20 ng/mL) OR = 2.6 (95%CI: 2.4-3.2, P=0.02), hepatitis B e antigen negativity OR = 2.1 (95%CI: 2.2-3.1, P=0.02), low viral load (hepatitis B virus DNA < 100 IU/mL) OR = 3 (95%CI: 2.6-4.2, P = 0.01) and duration of HBsAg seropositivity (> 8 years) OR = 1.6 (95%CI: 1.15-2.6, P=0.04) were also associated with spontaneous HBsAg seroclearance. CONCLUSION: We found a strong correlation between normal vitamin D levels and spontaneous HBsAg seroclearance. | Mahmud Mahamid William Nseir Omar Abu Elhija Shimon Shteingart Ammad Mahamid Mosab Smamra Benjamin Koslowsky | 2013 | World Journal of Hepatology2013，5，6： | 14 |
| 8 | Differentiation of murine male germ cells to spermatozoa n a soft agar culture system显示文摘建立一在里面允许阴囊的细菌房间的发展到精子的 vitro 系统将为男不孕为精子发生和未来治疗的研究是珍贵的。在现在的学习,我们用三维的琼脂文化系统(囊) 处于 vitro 文化条件发展了,它有能力导致阴囊的细菌房间到达精子发生的最后的阶段,包括精子产生。从 7-day-old 老鼠的睾丸的生精的小管酶地被分裂,并且 intratubular 房间在在与胎儿的小牛浆液(FCS ) 补充的 RPMI 媒介的 SACS 的上面的层是有教养的。SACS 的更低的层包含了与 FCS 补充的仅仅 RPMI 媒介。在上面的层的殖民地在文化的 14 和 28 天以后被孤立并且根据他们的尺寸被分类。Immunofluorescence 和即时 PCR 被用来分析在无差别、区分的 spermatogonia 表示的特定的标记(Vasa, Dazl, OCT-4, C 工具包, GFR-α -1, CD9 和 α -6-integrin), meiotic 房间(LDH, Crem-1 和议会) 和 post-meiotic 房间(Protamine-1,精子酵素和 SP-10 ) 。我们的结果表明导致老鼠是可能的阴囊的 pre-meiotic 细菌房间扩大并且在囊导致他们的区别到精子。精子显示出正常形态学并且包含了 acrosomes。因此,我们的结果证明囊能为 pre-meiotic 鼠标细菌房间的成熟在 vitro 系统被用作一篇小说到 post-meiotic 阶段和词法上正常的精子。 | Mahmoud Abu Elhija Eitan Lunenfeld Stefan Schlatt Mahmoud Huleihel | 2012 | Asian Journal of Andrology2012，14，2： | 14 |
| 9 | Premature ejaculation:an update on definition and pathophysiology显示文摘Premature ejaculation(PE)is the most comm on male sexual dysfunction,which represents a diag no stic as well as a therapeutic challenge for physicians.However,no universally accepted definition is currently available for PE.As a result,physicians continue to diagnose patients with PE according to major guidelines set by the professional societies.These guidelines either recommend the use of validated questionnaires or patient-reported outcomes.Recent efforts directed toward classifying PE may help provide a better understanding of the prevalence and risk factors of this disorder.While the exact etiology of PE has not been clearly elucidated,several risk factors have been strongly reported in the literature.Clearly,to understand the revised definition of PE,its etiology and pathophysiology is necessary to improve the clinical management of this medical condition and form the basis of future research in this regard.In this review,we highlight the past and current definitions of PE and present an appraisal on the classifications and theories suggested for the etiopathogenesis of PE. | Mohammed Abu El-Hamd Ramadan Saleh Ahmad Majzoub | 2019 | Asian Journal of Andrology2019，21，5： | 12 |
| 10 | Microstructure and corrosion behavior of Mg-Sn-Ca alloys after extrusion显示文摘Mg-Sn-Ca alloys promise a reasonable corrosion resistance in combination with good creep resistance, likely due to the presence of Ca2-xMgxSn and other phases. The selected alloys with 3% Sn and Ca in the range of 1%-2% have been extruded in order to achieve more homogeneous microstructure compared with the as-cast alloys. Optical microscopy(OM) and X-ray diffraction(XRD) techniques were used to study the microstructure and phases of these alloys. The corrosion behavior of these alloys was investigated by means of salt spray test and potentio-dynamic measurements. The results obtained on the alloys Mg-3Sn (T3), Mg-3Sn-1Ca (TX31), and Mg-3Sn-2Ca (TX32) indicate the presence of the same phases in as-cast and after extrusion, namely Mg2Sn, Ca2-xMgxSn, and Ca2-xMgxSn/Mg2Ca, respectively. However, due to the occurrence of extensive recrystallization in the extrusion process, the grain size has significantly reduced after extrusion. The reduction leads to the improvement of the corrosion resistance after extrusion which is then comparable with the commercial alloy AZ91D. | T. ABU LEIL N. HORT W. DIETZEL C. BLAW ERT Y. HUANG K. U. KAINER K. P. RAO | 2009 | 中国有色金属学会会刊:英文版2009，19，1： | 12 |
| 11 | Spatial distribution and source identification of heavy metal pollution in roadside surface soil:a study of Dhaka Aricha highway,Bangladesh显示文摘Introduction:In this study,metal pollution and their sources in surface soils were evaluated by pollution indices and multivariate statistical techniques in association with a geographical information system(GIS).Methods:Surface soil samples were collected in dry season from different locations of Dhaka Aricha highway and analyzed by energy dispersive X-ray fluorescence(EDXRF).Results:Thirteen different metals were found in the tested samples.Pollution indices are determined by enrichment factor in an order of Zr>Sn>P>Mn>Zn>Rb>Fe>Ba>Sr>Ti>K>Ca>Al.The resulting geoaccumulation index(Igeo)value shows the following order:Sn>Zr>P>Mn>Zn>Rb>Fe>Ba>Ti>Sr>K>Ca>Al.Contamination factors(CFs)of the metals range from 1.422 to 3.979(Fe);0.213 to 1.089(Al);0.489 to 3.484(Ca);1.496 to 2.372(K);1.287 to 3.870(Ti);2.200 to 14.588(Mn);5.938 to 56.750(Zr);0.980 to 3.500(Sr);2.321 to 4.857(Rb);2.737 to 6.526(Zn);16.667 to 27.333(Sn);3.157 to 16.286(P);and 0.741 to 3.328(Ba).Pollution load index calculated from the CFs indicates that soils are strongly contaminated by Zr and Sn.Principal component analysis(PCA)of parameters exhibits three major components.R-mode cluster analysis reveals three distinct groups in both site and metal basis clustering that shows a similar pattern with the PCA.Conclusions:These results might be helpful for future monitoring of further increase of heavy metal concentrations in surface soils along highways. | Fahad Ahmed A.N.M.Fakhruddin M.D.Toufick Imam Nasima Khan Tanzir Ahmed Khan Md.Mahfuzur Rahman Abu Tareq Mohammad Abdullah | 2016 | Ecological Processes2016，5，1： | 11 |
| 12 | Antioxidant, antimicrobial and cytotoxic potential of condensed tannins from Leucaena leucocephala hybrid-Rendang显示文摘Condensed tannins(CTs)are one of the promising compounds due to their potentially health-promoting qualities.In this study,CTs were extracted from a Leucaena leucocephala hybrid-Rendang and subjected to various biological studies including antioxidant(using Ferric reducing antioxidant power(FRAP),DPPH and ABTS radical scavenging assay),anti-microbial(against different pathogens)and cytotoxic activities(toward human breast adenocarcinoma(MCF-7),human colon carcinoma(HT29),human cervical carcinoma(HeLa)and human liver carcinoma(HepG2)cell lines)in cancer cells through in vitro experiments.The structural characteristics and purity of CTs extract were determined using 13C NMR.The results showed that CTs exhibited higher in vitro antioxidant activities(2257.12±80.55 mg TEAC/g extract,605.3±1.82 mg TEAC/g extract and 1014.03±1.20 mg TEAC/g extract in FRAP,ABTS and DPPH assay,respectively)and demonstrated anti-microbial activities toward selected Gram’s positive and Gram’s negative bacteria tested with MIC and MBC value at 6.25–50 mg/mL.Furthermore,among other selected cancer cells,CTs also demonstrated cytotoxic activity toward human breast cancer cells(MCF-7)(IC50=38.33±2.08mg/mL).Characteristic of apoptosis such as cell shrinkage,nuclear condensation and apoptotic bodies were shown in MCF-7.These preliminary investigations have provided scientific rationale to use CTs as an alternative therapy for various oxidative and inflammatory associated diseases.©2016 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Mazni Abu Zarin Ho Yin Wan Azizul Isha Nurdin Armania | 2016 | Food Science and Human Wellness2016，5，2： | 9 |
| 13 | Effects of feeding whole linseed on ruminal fatty acid composition and microbial population in goats显示文摘The objective of the present study was to evaluate the effect of feeding different levels of whole linseed,as a source of n-3 polyunsaturated fatty acids(PUFA), on ruminal fatty acid composition and microbial population in the goat. Twenty-four crossbred Boer goats were assigned to 3 dietary treatments: LO(control), L10 and L20 containing 0,10%, or 20% whole linseed, respectively. The ruminal pH and concentration of total volatile fatty acids(VFA) were not affected by dietary treatments. The feeding of L10 and L20 diets produced higher(P < 0.05) molar proportions of acetate and lower(P < 0.05) molar proportions of butyrate and valerate than the LO diet. Molar proportions of myristic acid(C14:0) and palmitic acid(C16:0) were lower(P < 0.05) in the rumen of goats offered L10 and L20 diets than the control diet. However, stearic acid(C18:0), vaccenic acid(C18:1 trans-11), conjugated linoleic acid(CLA,C18:2 trans-10, cis-12) and a-lenolenic acid(C18:3 n-3) were higher(P < 0.05) in the rumen of goats fed L10 and L20 than L0. Both inclusion levels of linseed in the diet(L10 and L20) reduced the ruminal total bacteria, methanogens, and protozoa compared with LO(P < 0.05). The effect of the dietary treatments on cellulolytic bacteria, varied between the individual species. Both inclusion levels of linseed resulted in a significant decrease(P < 0.05) in the population of Fibrobacter succinogenes, and Rumunococus flavefaciens compared with LO, with no significant difference between the groups fed linseed diets. The population of Rumunococus albus was not affected by the different dietary treatments. It was concluded that inclusion of whole linseed in the diet of goats could increase the concentration of PUFA in the rumen, and decrease the population of F. succinogenes, R. flavefaciens, methanogens and protozoa in rumen liquid of goats. | Kamaleldin Abuelfatah Abu B.Zuki Yeng M.Goh Awis Q.Sazili Abdelrahim Abubakr | 2016 | Animal Nutrition2016，，4： | 7 |
| 14 | Antioxidant activity and phytochemical screening of the methanol extracts of Euphorbia hirta L显示文摘Objective:To assess antioxidant activities of different parts of Euphorbia hirta(E.hirta),and to search for new sources of safe and inexpensive antioxidants.Methods:Samples of leaves,stems, flowers and roots from E.hirta were tested for total phenolic content,and flavonoids content and in vitro antioxidant activity by diphenyl-1-picrylhydrazyl(DPPH) assay and reducing power was measured using cyanoferrate method.Results:The leaves extract exhibited a maximum DPPH scavenging activity of(72.96±0.78)%followed by the flowers,roots and stems whose scavenging activities were(52.45±0.66)%,(48.59±0.97)%,and(44.42±0.94)%,respectively.The standard butylated hydroxytoluene(BHT) was(75.13±0.75)%.The IC50,for leaves,flowers,roots,stems and BHT were 0.803,0.972,0.989,1.358 and 0.794 mg/mL,respectively.The reducing power of the leaves extract was comparable with that of ascorbic acid and found to be dose dependent. Leaves extract had the highest total phenolic content[(206.17±1.95) mg GAE/g],followed by flowers,roots and stems extracts which were(117.08±3.10) mg GAE/g,(83.15±1.19) mg GAE/g,and (65.70±1.72) mg GAE/g,respectively.On the other hand,total flavonoids content also from leave had the highest value[(37.970±0.003) mg CEQ/g],followed by flowers,roots and stems extracts which were(35.200±0.002) mg CEQ/g,(24.350±0.006) mg CEQ/g,and(24.120±0.004) mg CEQ/ g,respectively.HPTLC bioautography analysis of phenolic and antioxidant substance revealed phenolic compounds.Phytochemical screening of E.hirta leaf extract revealed the presence of reducing sugars,terpenoids,alkaloids,steroids,tannins,flavanoids and phenolic compounds. Conclusions:These results suggeste that E.hirta have strong antioxidant potential.Further study is necessary for isolation and characterization of the active antioxidant agents,which can be used to treat various oxidative stress-related diseases. | Abu Arra Basma Zuraini Zakaria Lacimanan Yoga Latha Sreenivasan Sasidharan | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，5： | 7 |
| 15 | 生长激素受体信号相关因子在斑马鱼中的比较表达分析及GHR信号通路体内研究模型的建立(英文)显示文摘GHR信号通路在动物出生后的生长中扮演着重要角色。实验利用斑马鱼模型研究了GHR信号相关基因在成体组织、胚胎发育以及幼体期的表达情况,这些基因包括gh、ghra、ghrb、jak2a、jak2b、stat5.1、stat5.2、igf1、c-fos、socs1和socs2。值得关注的是,上述的大部分基因都存在母源性表达,且它们的合子表达均起始在体节早期之前。这说明在有功能性的脑垂体形成之前和完善的循环系统建立之前,GH及GH信号相关因子就已经存在于早期胚胎中,因此GH很可能是控制胚胎发育的一系列自分泌/旁分泌生长因子中的一员。同时,我们发现成体组织的socs表达水平与GH信号靶基因igf1和c-fos的表达呈某种程度的负相关。我们利用实时定量PCR技术和荧光素酶分析技术,通过注射GH和GHR表达载体,在斑马鱼胚胎中分析了它们促进GH信号靶基因c-fos和igf1转录活性以及GH应激启动子spi2.1活性的能力。由此,研究利用斑马鱼胚胎建立一个体内研究模型来评估发育过程中的GH信号激活(GHSA)。在受精后1天(dpf)和3dpf斑马鱼胚胎中,单独过表达gh或ghr均可以显著刺激GHSA,这表明在1dpf的斑马鱼胚胎中即存在功能性的GH和GHR蛋白表达,而这一时期是在功能性垂体的形成之前的。gh以及ghr的协同过表达则可以显著放大gh或ghr单独过表达的GHSA效果。 | Abu Shufian Ishtiaq Ahmed 于力群 朱作言 孙永华 | 2011 | 水生生物学报2011，35，5： | 6 |
| 16 | Sedimentary and geochemical evidence of Eocene climate change in the Xining Basin, northeastern Tibetan Plateau显示文摘The northeastern Tibetan Plateau began to grow during the Eocene and it is important to understand the climatic history of Asia during this period of so-called ‘doubthouse' conditions. However, despite major advances in the last few decades,the evolutionary history and possible mechanisms of Eocene climate change in the northeastern Tibetan Plateau remain unclear.The Xining Basin in the northeastern Tibetan Plateau contains a continuous sequence of Early to Late Eocene non-marine sediments which provides the opportunity to resolve long-term climate changes during this period. In this study, we report the results of analyses of lithofacies, sediment color and geochemistry of bulk samples collected from the Xijigou section of the Xining Basin. An abrupt lithofacies change between the Early(~52–40 Ma) and Late Eocene(~40–34 Ma) indicates a change in the depositional environment from a shallow lake to a playa lake in response to a significant climatic shift. During ~52–40 Ma,higher values of sediment redness(a*), redness/lightness(a*/L*) and higher modified Chemical Index of Weathering(CIW′)indicate a relatively warm and humid climate, while from ~40–34 Ma the lower values of a*, a*/L*and lower CIW′ imply subhumid to semi-arid climatic conditions. The paleoclimatic records indicate a long-term(~52–34 Ma) trend of decreasing chemical weathering, consistent with global climate change. An abrupt sharp excursion of the proxy records during ~42–40 Ma suggests a relatively brief warm interval, corresponding to the Middle Eocene Climatic Optimum(MECO). We suggest that global cooling substantially reduced humidity in inner Asia, resulting in sub-humid to semi-arid climatic conditions after 40 Ma in the Xining Basin, which may have been responsible for the long-term trend of decreasing chemical weathering during the Eocene. | Abu Sadat Md SAYEM Zhengtang GUO Haibin WU Chunxia ZHANG Fan YANG Guoqiao XIAO Zhilin HE | 2018 | Science China Earth Sciences2018，61，9： | 6 |
| 17 | Simulation of Vortex-Induced Vibrations of A Cylinder Using ANSYS CFX显示文摘In this paper, vortex-induced vibrations of a cylinder are simulated by use of ANSYS CFX simulation code. The cylinder is treated as a rigid body and transverse displacements are obtained by use of a one degree of freedom spring damper system. 2-D as well as 3-D analysis is performed using air as the fluid. Reynolds number is varied from 40 to 16000 approx., covering the laminar and turbulent regimes of flow. The experimental results of(Khalak and Williamson, 1997) and other researchers are used for validation purposes. The results obtained are comparable. | Abu Bakar IZHAR Arshad Hussain QURESHI Shahab KHUSHNOOD | 2014 | China Ocean Engineering2014，28，4： | 5 |
| 18 | Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation. | Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon | 2012 | World Journal of Gastrointestinal Oncology2012，4，5： | 5 |
| 19 | Anti-bacterial activity and brine shrimp lethality bioassay of methanolic extracts of fourteen different edible vegetables from Bangladesh显示文摘Objective:To investigate the antibacterial and cytotoxic activity of fourteen different edible vegetables methanolic extract from Bangladesh.Methods:The antibacterial activity was evaluated using disc diffusion assay method against 12 bacteria(both gram positive and gram negative).The plant extracts were also screened for cytotoxic activity using the brine shrimp lethality bioassay method and the lethal concentrations(LC_(50))were determined at confidence intervals by analyzing the data on a computer loaded with'Finney Programme??Results:All the vegetable extracts showed low to elevated levels of antibacterial activity against most of the tested strains(zone of inhibition=5-28 mm).The most active extract against all bacterial strains was from Xanthium indicum which showed remarkable antibacterial activity having the diameter of growth inhibition zone ranging from 12 to 28 mm followed by Alternanthera sessilis(zone of inhibition=6-21 mm).All extracts exhibited considerable general toxicity towards brine shrimps.The LC_(50)value of the tested extracts was within the range of 8.447 to 60.323μg/mL with respect to the positive control(vincristine sulphate)which was 0.91μg/mL.Among all studied extracts,Xanthium indicum displayed the highest cytotoxic effect with LC_(50)value of 8.447μg/mL.Conclusions:The results of the present investigation suggest that most of the studied plants are potentially good source of antibacterial and anticancer agents. | M.Obayed Ullah Mahmuda Haque Kaniz Fatima Urmi Abu Hasanat Md.Zulfiker Elichea Synthi Anita Momtaj Begum Kaiser Hamid | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，1： | 5 |
| 20 | Inhibition of Ehrlich ascites carcinoma by Manilkara zapota L.stem bark in Swiss albino mice显示文摘Objective:To evaluate the antitumor activity of Manilkara zapota(M.zapota) L.stem bark against Ehrlich ascites carcinoma(EAC) in Swiss albino mice.Methods:The in vivo antitumour activity of the ethyl acetate extract of stem bark of M.zapota L.(EASM) was evaluated at 50,100 and 200 mg/kg bw against EAC using mean survival time.After administration of the extract of M.zapota,viable EAC cell count and body weight in the EAC tumour hosts were observed.The animal was also observed for improvement in the haematological parameters(e.g.,heamoglobin content,red and white blood cells count and differential cell count) after EASM treatment. Results:Intraperitoneal administration of EASM reduced viable EAC cells,increased the survival lime,and restored altered haematological parameters.Significant efficacy was observed for EASM at 100 mg/kg dose(P<0.05).Conclusions:It can be concluded that the elhyl acetate extract of stem bark of M.zapota L.possesses significant antitumour activity. | M Abu Osman M Mamunur Rasbid M Abdul Aziz M Rowshahul Habib M Rezaul karim | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，6： | 5 |
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