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| 1 | 人血浆硫氧化还原蛋白80随着年龄增长而增加,并在载脂蛋白E基因敲除小鼠中诱导炎症、血管生成和动脉粥样硬化显示文摘硫氧化还原蛋白(thioredoxin,TRX)1是一种普遍存在的12kD的蛋白质,可产生抗氧化和抗炎作用。由巨噬细胞产生的截断形式称为TRX80,其可诱导促炎细胞因子的上调。TRX80还促进小鼠腹膜和人巨噬细胞向促炎M1表型的分化。方法:使用特异性酶联免疫吸附试验测定血浆TRX1和TRX80水平。 | 刘莉 叶鹏 Couchie D Vaisman B Abderrazak A Mahmood DFD Hamza MM Canesi F Diderot V El Hadri K Nègre-Salvayre AE Le Page A Fulop T Remaley AT Rouis M | 2017 | 中华高血压杂志2017，25，6： | 9 |
| 2 | HBV vaccine efficacy and detection and genotyping of vaccineé asymptomatic breakthrough HBV infection in Egypt显示文摘AIM:To evaluate the impact of mass vaccination against the hepatitis B virus (HBV) in Egypt,and to search for vaccinee asymptomatic breakthrough HBV infection and its genotype.METHODS:Seven hundred serum samples from vaccinated children and adults (aged 2-47 years) were used for quantitative and qualitative detection of HBsAb by ELISA.Three hundred and sixty serum samples representing undetectable or low or high HBsAb were screened for markers of active HBV infection (HBsAg,HBcAb (IgG) and HBeAb by ELISA,plus HBsAg by AxSYM) and HBV-DNA genotyping by nested multiplex PCR and by DNA sequencing.RESULTS:It was found that 65% of children aged 2-4 years,and 20.5% aged 4-13 years,as well as 45% adults were good responders to HBV vaccination mounting protective level HBsAb.Poor responders were 28%,59.5% and 34%,and non-responders were 7%,20% and 21% respectively,in the three studied groups.Markers of asymptomatic HBV infections were HBsAg detected by ELISA in 2.5% vs 11.39% by AxSYM.Other markers were HBcAb (IgG) in 1.38%,HBeAb in 0.83%,and HBV-DNA in 7.8%.All had HBV genotype E infection.CONCLUSION:It is concluded that HBV vaccine is efficient in controlling HBV infection among children and adults.The vaccine breakthrough infection was by HBV genotype E.A booster dose of vaccine is recommended,probably four years after initial vaccination. | Eman AE Abushady Magda MA Gameel John D Klena Salwa F Ahmed Kouka SE Abdel-wahab Sanya M Fahmy | 2011 | World Journal of Hepatology2011，3，6： | 5 |
| 3 | Human immunodeficiency virus-related primary central nervous system lymphoma: factors influencing survival in 111 patients显示文摘BACKGROUND: The current study evaluated factors influencing survival in patients diagnosed with human immunodeficiency virus (HIV)-related primary central nervous system lymphoma (PCNSL), with a focus on the effects of therapeutic radiotherapy (RT) and highly active antiretroviral therapy (HAART). METHODS: A retrospective chart review of patients with a diagnosis of HIV-related PCNSL at one of five university hospitals between 1987 and 1998 was performed. Clinical details including antiretroviral agent use, brain imaging scan results, RT use, and survival outcomes were recorded. RESULTS: One hundred eleven patients with HIV-related PCNSL were identified. The annual incidence decreased significantly between 1992 and 1995 and between 1996 and 1998 (P=0.04). | Newell ME Hoy JF Cooper SG DeGraaff B Grulich AE Bryant M Millar JL Brew BJ Quinn DI | 2004 | 中国神经肿瘤杂志2004，2，2： | 4 |
| 4 | The stimulation of prostaglandin synthesis by micromovement in fracture healing显示文摘 | Goodship AE Norrodin N Francis M | 1992 | Micromovement in Orthopaedics1992，3134，： | 2 |
| 5 | Toward a theory of student satisfaction:an exploratory study of the 'Quality of Student Life'显示文摘 | Benjamin M Hollings AE | 1995 | Journal of College Student Development1995，36，6： | 1 |
| 6 | Progesterone or progestogen-releasing intrauterine systems for heavy menstrual bleeding 显示文摘 | Lethaby AE Cooke I Rees M | 2005 | Cochrane Database Syst Rev2005，19，00： | 1 |
| 7 | Human tryptase fibrinogenolysis is optimal at acidic pH and generates anticoagulant fragments in the presence of the anti - tryptase monoclonal antibody B12显示文摘 | Lawson AE Carr M | 1997 | J Immunol1997，159，7： | 1 |
| 8 | Laparoscopic gastric banding prevents type 2 diabetes and arterial hypertension and induces their remission in morbid obesity:a 4-year case-controlled study显示文摘 | Pontiroli AE Folli F Paganelli M | 2005 | Diabetes Care2005，28，11： | 1 |
| 9 | Potential of siderophore-producing bacteria for improving heavy metal phytoextraction显示文摘 | Rajkumar M Ae N Prasad MNV | 2009 | Trends in Biotechnology2009，28，3： | 1 |
| 10 | Prevalence ofhuman papillomavirus genotypes and relate abnormali-ties of cervical cytological results among HIV-1infec-ted women in Rochester,New York显示文摘 | Luque AE Jabeen M Messing S | 2006 | JID2006，19，4： | 1 |
| 11 | Soluble CD 36 in plasma is increased in patients with symptomatic atherosclerotic ca-rotid plaques and is related to plaque instability显示文摘 | Handberg A Skjelland M Michelsen AE | 2008 | Stroke2008，39，11： | 1 |
| 12 | Cyclization of geranylgeranyl diphosphate to taxa-4(5),11(12)-diene is the committed step of taxol biosynthesis in Pacific yew显示文摘 | Koepp AE Hezari M Zajicek J 1995 | 1995 | J Biol Chem1995，270，： | 1 |
| 13 | Genotypicdifferences incadmium uptakeanddistributioninsoybeans 显示文摘 | AraoT Ae N Sugiyama M | 2003 | Plant- Soil2003，251，： | 1 |
| 14 | Interleukin-1 receptor antagonist and interleukin-6 for early diagnosis of neonatal sepsis 2 days before clinical manifestation显示文摘 | Kfister H Weiss M Willeitner AE | 1998 | Lancet1998，352，9136： | 1 |
| 15 | Review:diabetic ketoacidosis and hyperglycemic hyperosmo1ar nonketotic syndrome显示文摘 | Umpierrez GE Khajavi M Kitabchi AE | 1996 | Am J Med Sci1996，311，5： | 1 |
| 16 | The potential for be-ta-structure in the repeat domain of Tau protein determinesaggregation,synaptic decay, neuronal loss,and coassemblywith endogenous Tau in inducible mouse models of Tauopathy显示文摘 | Mocanu M Nissen AE Mandelkow EM | 2008 | J Neurosci2008，28，3： | 1 |
| 17 | Effects of glucagon-like peptidc-1 receptor agonists on weight loss :systematic review and meta - analyses of randomised controlled trials显示文摘 | VilsbOll T Christensen M Junker AE | 2012 | BMJ2012，344，： | 1 |
| 18 | Preven-ting disability in elderly people 显示文摘 | Stuck AE Beck JC Egger M | 2004 | Lancet2004，364，9446： | 1 |
| 19 | Effect of endoplasmie retieulum stress precondi- tioning on eytotoxicity of clinically relevant nephrotoxins in renal cell lines 显示文摘 | Peyrou M Cribb AE | 2007 | Toxieol In Vitro2007，21，5： | 1 |
| 20 | Radiofrequency assisted liver resection:Analysis of 604 consecutive cases显示文摘 | Pai M Frampton AE Mikhail S | 2012 | Eur J Surg Oncol2012，38，3： | 1 |
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