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| 1 | Further analyses of variation of ribosome DNA copy number and polymorphism in ciliates provide insights relevant to studies of both molecular ecology and phylogeny显示文摘Sequence-based approaches, such as analyses of ribosome DNA(rDNA) clone libraries and high-throughput amplicon sequencing, have been used extensively to infer evolutionary relationships and elucidate the biodiversity in microbial communities.However, recent studies demonstrate both r DNA copy number variation and intra-individual(intra-genomic) sequence variation in many organisms, which challenges the application of the rDNA-based surveys. In ciliates, an ecologically important clade of microbial eukaryotes, rDNA copy number and sequence variation are rarely studied. In the present study, we estimate the intraindividual small subunit rDNA(SSU r DNA) copy number and sequence variation in a wide range of taxa covering nine classes and 18 orders of the phylum Ciliophora. Our studies reveal that:(i) intra-individual sequence variation of SSU rDNA is ubiquitous in all groups of ciliates detected and the polymorphic level varies among taxa;(ii) there is a most common version of SSU rDNA sequence in each cell that is highly predominant and may represent the germline micronuclear template;(iii)compared with the most common version, other variant sequences differ in only 1–3 nucleotides, likely generated during macronuclear(somatic) amplification;(iv) the intra-cell sequence variation is unlikely to impact phylogenetic analyses;(v) the rDNA copy number in ciliates is highly variable, ranging from 103 to 106, with the highest record in Stentor roeselii. Overall,these analyses indicate the need for careful consideration of SSU r DNAvariation in analyses of the role of ciliates in ecosystems. | Yurui Wang Chundi Wang Yaohan Jiang Laura A.Katz Feng Gao Ying Yan | 2019 | Science China(Life Sciences)2019，62，2： | 7 |
| 2 | A paradox: rapid evolution rates of germline-limited sequences are associated with conserved patterns of rearrangements in cryptic species of Chilodonella uncinata(Protista, Ciliophora)显示文摘Some of the most extreme genome wide rearrangements are found in ciliates, which are unique in possessing both germline micronucleus and somatic macronucleus in every cell/organism. A series of DNA rearrangement events, including DNA elimination, chromosomal fragmentation, gene unscrambling and alternative processing, happen during macronuclear development. To assess the molecular evolution of macronuclear and germline-limited sequences in different cryptic species of Chilodonella uncinata, we characterized the actin, α-tubulin and β-tubulin genes in the micronucleus and macronucleus genomes of USA-SC2 strain and compared them with other strains(i.e. cryptic species). Three main results are:(i) rearrangement patterns between germline and soma are conserved for each gene among the cryptic species of C. uncinata;(ii) in contrast, the germlinelimited regions are highly divergent in sequence and length among the cryptic species;(iii) pointer shifting is frequent among the cryptic species. We speculate that pointer sequences may serve as the buffer between the conserved macronuclear destined sequences and rapidly-evolving internal eliminated sequences. The data combined with previous studies demonstrate the plasticity of gene rearrangement among different groups of ciliates and add to the growing data for the role of genome rearrangements in species differentiation. | Tengteng Zhang Chundi Wang Laura A.Katz Feng Gao | 2018 | Science China(Life Sciences)2018，61，9： | 5 |
| 3 | The assessment of regional gut transit times in healthy controls and patients with gastroparesis using wireless motility technology显示文摘 | I.SAROSIEK K. H.SELOVER L. A.KATZ J. R.SEMLER G. E.WILDING J. M.LACKNER M. D.SITRIN B.KUO W. D.CHEY W. L.HASLER K. L.KOCH H. P.PARKMAN J.SAROSIEK R. W.MCCALLUM | 2009 | Alimentary Pharmacology & Therapeutics2009，，2： | 2 |
| 4 | Comparison of gastric emptying of a nondigestible capsule to a radio‐labelled meal in healthy and gastroparetic subjects显示文摘 | B.KUO R. W.McCALLUM K. L.KOCH M. D.SITRIN J. M.WO W. D.CHEY W. L.HASLER J. M.LACKNER L. A.KATZ J. R.SEMLER G. E.WILDING H. P.PARKMAN | 2007 | Alimentary Pharmacology & Therapeutics2007，，2： | 1 |
| 5 | The chronology and intellectual trajectory of American entrepreneurship education 1876-1999显示文摘 | Jerome A.Katz | | 0，，18： | 1 |
| 6 | OPTN Policy Regarding Prioritization of Patients with Hepatopulmonary Syndrome: Does It Provide Equitable Organ Allocation?显示文摘 | B. M.Sulieman L. G.Hunsicker D. A.Katz M. D.Voigt | 2008 | American Journal of Transplantation2008，，5： | 1 |
| 7 | High quality large single crystals of metal halide perovskites for optoelectronic applications显示文摘As the technological development of large single-crystalline wafers have revolutionized many industries including electronics and photovoltaics,one can predict that the availability of large single-crystalline perovskite crystals and wafers can revolutionize its broad applications in photodetectors,solar cells,LEDs,lasers,etc.In 2015,Liu et al.[1]at Shaanxi Normal University developed a reactive inverse-temperature crystallization(RITC)method and harvested high quality MAPbI_3 | Eugene A.Katz | 2017 | Science China Chemistry2017，60，10： | 0 |
| 8 | 董事会信息保密战显示文摘创建互相信任的文化可能是董事会防范信息泄露的最佳措施,董事长应该以身作则。 | David A.Katz Laura A.McIntosh | 2014 | 董事会2014，，3： | 0 |
| 9 | 《修辞语言与思维》述评显示文摘<修辞语言与思维>(Figurative Languages and Thought)一书的作者是Albert N.Katz,Cristina Cacciari,Raymond W.Gibbs,Jr.和Mark Turner,1998年由Oxford UnIversity Press出版社出版. | A.Katz 王全智 | 2003 | 当代语言学2003，5，3： | 0 |
| 10 | Modeling the impact of changing sexual behaviors with opposite-sex partners and STI testing among women and men ages 15-44 on STI diagnosis rates in the United States 2012-2019显示文摘Objective:To estimate the potential contributions of reported changes in frequency of penile-vaginal sex(PVS),condom use and STI screening to changes in gonorrhea and chlamydial diagnoses from 2012 to 2019.Methods:An agent-based model of the heterosexual population in the U.S.simulated the STI epidemics.Baseline was calibrated to 2012 diagnosis rates,testing,condom use,and frequency of PVS.Counterfactuals used behaviors from the 2017-2019 NSFG,and we evaluated changes in diagnosis and incidence rates in 2019.Results:Higher testing rates increased gonorrhea and chlamydia diagnosis by 14%and 13%,respectively,but did not reduce incidence.Declining frequency of PVS reduced the diagnosis rate for gonorrhea and chlamydia 6%and 3%respectively while reducing incidence by 10%and 9%respectively.Declining condom use had negligible impact on diagnosis and incidence.Conclusion:Understanding how changing behavior drives STI incidence is essential to addressing the growing epidemics.Changes in testing and frequency of PVS likely contributed to some,but not all,of the changes in diagnoses.More research is needed to understand the context within which changing sexual behavior and testing are occurring. | Deven T.Hamilton David A.Katz Laura T.Haderxhanaj Casey E.Copen Ian H.Spicknall Matthew Hogben | 2023 | Infectious Disease Modelling2023，8，4： | 0 |
| 11 | All carbon non-covalent exohedral hybrids:C60 aggregates on nanotube networks显示文摘Exohedral van der Waals(vd W) hybrids comprising pristine carbon nanotubes(CNTs) and C_(60) fullerenes are expected to enable the engineering of carbonaceous materials with tunable physical and chemical properties due to the unperturbed sp2 hybridization of the comprising allotropes. In spite of theoretical predictions, experimental realization of exohedral non-covalent hybridization of unmodified C_(60) fullerenes and CNTs was not reported before, probably due to the relatively strong inter-fullerene and inter-tube interactions that drive the system toward phase separation and the formation of fullerene crystals and CNTs bundles. Here we describe a two-step process for preparation of C_(60)–CNTs hybrids. The first step is based on solution-assembly of random, 3 D-networks of individual, pristine CNTs followed by fast solvent-quenching. In the second step sublimated fullerenes are deposited onto the pre-assembled networks where structural defects serve as nucleation points for fullerite nanocrystals. Annealing at low temperature(80 °C) results in re-organization of the C_(60) nanocrystals into nanometric layers, forming a CNT-C_(60) core-shell like cylindrical hybrids. Raman characterization and the observed high mobility of the fullerenes at the CNT surface support the assumption that the exohedral hybrids are of vd W type. The approach presented here offers a pathway for preparation of exohedral hybrids with controlled nanomorphology: CNTs-networks decorated by nanometric C_(60) crystals and CNTs-3 D-networks coated by a shell of non-covalently bonded mono-or multi-layers of C_(60) molecules that may serve to shape the nanomorphology of the active layer in polymer-fullerene bulk-heterojunction solar cells. | Evgenee Yekymov Celine Bounioux Racheli Itzhak-Cohen Leila Zeiri Emil Shahnazaryan Eugene A.Katz Rachel Yerushalmi-Rozen | 2018 | Journal of Energy Chemistry2018，27，4： | 0 |
| 12 | BILATERAL OPHTHALMIC CAROTHID A- NEURYSM THAT MIMICS NORMAL TEN-SION GLAUCOMA显示文摘A 47 years old woman who was treated like NTG, with visual fields changes that are similar to those in NTG. She was clamped both ophthalmic arteries anuerysm.Two years before she was treated like NTG with beta-blockers, the main symptom was mi-grane like headackes. | G.Alfaro F.Gil J.Fromow I.Ordonez A.Katz | 2003 | 国际眼科杂志2003，3，1： | 0 |
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