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| 1 | Neurological consequences of systemic inflammation in the premature neonate显示文摘Despite substantial progress in neonatal care over the past two decades leading to improved survival of extremely premature infants, extreme prematurity continues to be associated with long term neurodevelopmental impairments. Cerebral white matter injury is the predominant form of insult in preterm brain leading to adverse neurological consequences. Such brain injury pattern and unfavorable neurologic sequelae is commonly encountered in premature infants exposed to systemic inflammatory states such as clinical or culture proven sepsis with or without evidence of meningitis, prolonged mechanical ventilation, bronchopulmonary dysplasia, necrotizing enterocolitis and chorioamnionitis. Underlying mechanisms may include cytokine mediated processes without direct entry of pathogens into the brain, developmental differences in immune response and complex neurovascular barrier system that play a critical role in regulating the cerebral response to various systemic inflammatory insults in premature infants. Understanding of these pathologic mechanisms and clinical correlates of such injury based on serum biomarkers or brain imaging findings on magnetic resonance imaging will pave way for future research and translational therapeutic opportunities for the developing brain. | Aparna Patra Hong Huang John A.Bauer Peter J.Giannone | 2017 | Neural Regeneration Research2017，12，6： | 5 |
| 2 | 新型电弧控制机构对双丝气体保护焊的影响显示文摘简单阐述了高效双丝焊TPS/i TWIN,并介绍了多重脉冲控制(PMC)的功能以及新的焊接工艺功能,尤其是PulseSync,并进行了焊接试验。结果表明:这些工艺特点对厚板碳素钢角焊缝和对接焊缝的焊接速度和熔深有影响。 | S.Schartner D.Soellinger P.Lumpf A.Bauer K.Schneider M.Schoerghuber | 2020 | 金属加工(热加工)2020，0，4： | 3 |
| 3 | Complementary and Alternative Medicine Therapies for Chronic Pain显示文摘Pain afflicts over 50 million people in the US, with 30.7% US adults suffering with chronic pain. Despite advances in therapies, many patients will continue to deal with ongoing symptoms that are not fully addressed by the best conventional medicine has to offer them. The patients frequently turn to therapies outside the usual purview of conventional medicine(herbs, acupuncture, meditation, etc.) called complementary and alternative medicine(CAM). Academic and governmental groups are also starting to incorporate CAM recommendations into chronic pain management strategies. Thus, for any physician who care for patients with chronic pain, having some familiarity with these therapies—including risks and benefits—will be key to helping guide patients in making evidence-based, well informed decisions about whether or not to use such therapies. On the other hand, if a CAM therapy has evidence of both safety and efficacy then not making it available to a patientwho is suffering does not meet the need of the patient. We summarize the current evidence of a wide variety of CAM modalities that have potential for helping patients with chronic pain in this article. The triad of chronic pain symptoms, ready access to information on the internet, and growing patient empowerment suggest that CAM therapies will remain a consistent part of the healthcare of patients dealing with chronic pain. | Brent A.Bauer Jon C.Tilburt Amit Sood 李光熙 王师菡 | 2016 | Chinese Journal of Integrative Medicine2016，22，6： | 3 |
| 4 | Chinese Medicine and Integrative Medicine in the United States显示文摘Health wellness is a state of the homeostasis.Chinese medicine incorporate many concept including holistic medicine and individualized medicine to promote health wellness.Different domains of Chinese medicine were exclusively adopted after the first introduction of acupuncture to USA.Mayo as one of the best USA hospital created a foundation for the more widespread introduction of Chinese medicine into the US especially on the health wellness promotion. | Brent A.Bauer | 2015 | Chinese Journal of Integrative Medicine2015，21，8： | 3 |
| 5 | Effects of transdermal magnesium chloride on quality of life for patients with fibromyalgia: a feasibility study显示文摘BACKGROUND: Fibromyalgia is a syndrome characterized by chronic pain, fatigue, depression, and sleep disturbances. Its primary cause is unclear. Several studies have reported decreased intracellular magnesium levels in patients with fibromyalgia and have found negative correlation between magnesium levels and fibromyalgia symptoms.OBJECTIVE: To gather preliminary data on whether transdermal magnesium can improve quality of life for women who have fibromyalgia.DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS: This is a patient questionnaires and survey in a fibromyalgia clinic at a tertiary medical center. Forty female patients with the diagnosis of fibromyalgia were enrolled. Each participant was provided a spray bottle containing a transdermal magnesium chloride solution and asked to apply 4 sprays per limb twice daily for 4 weeks. Participants were asked to complete the Revised Fibromyalgia Impact Questionnaire, SF-36v2 Health Survey, and a quality-of-life analog scale at baseline, week 2, and week 4.MAIN OUTCOME MEASURE: Questionnaire and survey scores, evaluated through intent-to-treat and per-protocol analyses.RESULTS: Twenty-four patients completed the study(mean [SD] age, 57.2 [7.6] years; white, 95%; mean body mass index, 31.3 kg/m2). With intention-to-treat analysis, Revised Fibromyalgia Impact Questionnaire subscale and total scores were significantly improved at week 2 and week 4(total score, P = 0.001). Per-protocol analysis results were similar: all subscales of the Revised Fibromyalgia Impact Questionnaire were significantly improved at week 2 and week 4(total score, P = 0.001). CONCLUSION: This pilot study suggests that transdermal magnesium chloride applied on upper and lower limbs may be beneficial to patients with fibromyalgia.TRIAL REGISTRATION: Clinical Trials.gov.ldentifier NCT01968772. | Deborah J.Engen Samantha J.Mc Allister Mary O.Whipple Stephen S.Cha Liza J.Dion Ann Vincent Brent A.Bauer Dietlind L.Wahner-Roedler | 2015 | Journal of Integrative Medicine2015，13，5： | 2 |
| 6 | Stretching has no effect on tennis serve performance显示文摘 | Duane V.Knudson Guillermo J.Noffal Rafael E.Bahamonde Heef A.Bauer john R.Blackell | | 0，，03： | 1 |
| 7 | The Objective Severity Assessment of Atopic Dermatitis (OSAAD) score: validity, reliability and sensitivity in adult patients with atopic dermatitis显示文摘 | I.Angelova‐Fischer A.Bauer U. C.Hipler I.Petrov J.Kazandjieva T.Bruckner T.Diepgen N.Tsankov M.Williams T.W.Fischer P.Elsner J.W.Fluhr | 2005 | British Journal of Dermatology2005，，4： | 1 |
| 8 | A predictive accident-duration based decision-making module for rerouting in environments with V2V communication显示文摘Communication for cooperative traffic management increases convenience and efficiency in driving. Intelligent vehicles can collect information about the driving environment, the driver situation and, more importantly, information on other vehicles. While giving this information to the driver can be useful, there is also the possibility of presenting the driver with too much information. Existing vehicles already have some mechanisms to take certain actions if the driver fails to act. Future vehicles will need more complex decision-making modules which receive the raw data from all available sources, process this data and inform the driver about existing or impending situations and suggest, or even take actions. In this work, we explore the use of a decision-making module for accident situations that processes information from VANET communication and advises the driver based on the situation. Our decision-making algorithm is a simple and effective algorithm that can be implemented in each vehicle to assist the driver in situations where rerouting to avoid traffic congestion caused by an accident may be necessary. Our approach estimates accident duration and provides a rerouting for upcoming traffic. Our algorithm has been implemented and evaluated within an elegant traffic simulation system where both city and highway environments are considered, along with various proportions of V2V-equipped vehicles. Overall, the results indicate that using our decision-making module in vehicles shows great potential for improving performance of vehicular systems by reducing both travel and wait times and providing more accurate information on surrounding environments. | besat zardosht steven s.beauchemin michael a.bauer | 2017 | Journal of Traffic and Transportation Engineering(English Edition)2017，4，6： | 0 |
| 9 | Incorporation of integrative medicine education into undergraduate medical education:a longitudinal study显示文摘OBJECTIVE: Integrative medicine(IM) combines complementary medical approaches into conventional medicine and considers the whole person. We implemented a longitudinal IM short-course curriculum into our medical school education. This study aimed to evaluate the feasibility and effectiveness of the curriculum via knowledge and attitude surveys regarding IM among students. METHODS: A mandatory short IM curriculum across all years of medical school was created and taught by IM professionals and physician faculty members with expertise in integrative therapies. Graduating classes of 2015 and 2016 completed the same survey in their first and third years of medical school. Paired data analysis was done, and only students who completed surveys at both time points were included in final analyses. RESULTS: Of 52 students in each class, 17(33%) in the class of 2015 and 22(42%) in the class of 2016 completed both surveys. After the IM curriculum, students' knowledge of and comfort with several IM therapies—biofeedback, mindfulness, and the use of St. John's wort—improved significantly. Students' personal health practices also improved, including better sleep, exercise, and stress management for the class of 2015. Students graduating in 2016 reported decreased alcohol use in their third year compared with their first year.CONCLUSION: It is feasible to incorporate IM education into undergraduate medical education, and this is associated with improvement in students' knowledge of IM and personal health practices. | saswati mahapatra anjali bhagra bisrat fekadu zhuo li brent a.bauer dietlind l.wahner-roedler | 2017 | Journal of Integrative Medicine2017，15，6： | 0 |
| 10 | Saccharification versus simultaneous saccharification and fermentation of kraft pulp显示文摘Enzymes are a significant cost in cellulosic ethanol production,minimizing their use would be desirable as long as ethanol yields and productivities are not reduced.The aim was to evaluate the effects of enzyme dosage on conversion of cellulose to ethanol.Kraft pulp,an intermediate in paper production,was used to represent a fractionated cellulose feedstock.Trials were conducted in a 5 L BioFlow bioreactor(2-3 L working volume)with agitation rate varied(80-900 r/m)to provide acceptable mixing.Based on survey of the literature,an average dosage for cellulase(34 FPU/g glucan)andβ-glucosidase(135 CBU/g glucan)was calculated,and these were set as the 100%dosages.Dosages of 1%,7%,13%,33%,67%,100%,133%were tested,using Novozyme Celluclast 1.5 L(cellulase)and Novozyme 188(β-glucosidase)in a 4.8%(dry mass)kraft pulp slurry.Novozymes recommended dosages are at the low end of this spectrum,at 12 g/g glucan for Celluclast 1.5 L(35%dosage)and 1.2 g/g glucan for Novozyme 188(0.9%dosage).Saccharification trials(50oC)showed a typical dosage response,with the 133%dosage achieving the highest sugar concentration(~59 g/L glucose)and saccharification rate(2.45 g/L/h),with a specific rate of 2.2×10-4 g glucose/unit enzyme/h.However the 13%enzyme dosage resulted in the highest specific saccharification rate(2.9×10-4 g glucose/unit enzyme/h).Simultaneous saccharification and fermentation(SSF)trials(35oC)were conducted using Saccharomyces cerevisiae or Candida molischiana to compare enzyme dosages of 33%,67%,100%,and 133%.Ethanol titers and productivities were similar for trials with 67%or more of the literature average enzyme dosage,however were lower at the 33%enzyme dosage.Thus enzyme dosage can be substantially reduced from levels typically cited in the literature,but cannot be reduced to levels recommended by the manufacturer,without reduction in ethanol yield and productivity. | Nichole A.Bauer William R.Gibbons | 2012 | International Journal of Agricultural and Biological Engineering2012，5，1： | 0 |
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