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| 1 | Comparison of perceived pain and patients’ satisfaction with traditional local anesthesia and single tooth anesthesia: A randomized clinical trial显示文摘BACKGROUND Contemporary innovations in the area of local anesthesia have attempted to provide an absolutely pain free experience for patients.Since the introduction of Computer-Controlled Local Anesthetic Delivery Systems to dentistry,many studies have compared its efficacy and safety to conventional anesthesia.However,very few studies have compared single tooth anesthesia(STA)and traditional local anesthesia.AIM To compare pain rating,changes in blood pressure,and heart rate during the local anesthetic injection.The secondary objectives were to measure the patients’level of satisfaction and the differences in anesthetic efficiency between the STA system and traditional local infiltration.METHODS A randomized controlled trial was conducted and a total of 80 patients with dental restorative needs were enrolled for the study.The patients were evaluated for their general physical status and oral clinical findings before enrollment.Information regarding perceived pain,changes in heart rate and blood pressure,and patients’satisfaction was collected using an electronic data form and was analyzed using paired and unpaired t-tests.RESULTS No significant difference was noted in perceived pain(P=0.59)and systolic blood pressure(P=0.09)during anesthetic injection using both traditional and STA techniques.STA patients had a significantly higher heart rate during anesthesia,although a statistically significant difference was noted among the traditional anesthesia and the STA groups even before anesthesia.During the restorative procedure,less pain was perceived by STA patients on the Wong-Baker FACES pain scale,which was statistically significant(P<0.001).Analyses of post-procedure patient responses showed that STA patients had a significantly better treatment experience and preferred to have the same method of injection in the future(P=0.04).CONCLUSION STA system can provide less painful and more comfortable restorative treatment procedures in comparison to the traditional infiltration technique. | Mohammad I Al-Obaida Mehdiya Haider Rawan Hashim Wafa AlGheriri Sree Lalita Celur Samar A Al-Saleh Ebtissam M Al-Madi | 2019 | World Journal of Clinical Cases2019，7，19： | 8 |
| 2 | Flow cytometric detection of hepatitis C virus antigens in infected peripheral blood leukocytes: Binding and entry显示文摘AIM: We designed two synthetic-core-specific peptides core 1 (C1) and core 2 (C2), and an E1-specific peptide (E1). We produced specific polyclonal antibodies againstthese peptides and used the antibodies for detection of HCV antigens on surface and within infected peripheral blood leukocytes.METHODS: Peripheral blood from a healthy individual who tested negative for HCV RNA was incubated with HCV type 4 infected serum for 1 h and 24 h at 37 ℃. Cells were stained by direct and indirect immunofluorescence and measured by flow cytometry.RESULTS: After 1 h of incubation, antibodies against C1,C2, and E1 detected HCV antigens on the surface of 27%,26% and 73% of monocytes respectively, while 10%, 5% and 9% of lymphocytes were positive with anti-C1, anti-C2 and anti-E1 respectively. Only 1-3% of granulocytes showed positive staining with anti-C1, anti-C2 and anti E1 antibodies. After 24 h of incubation, we found no surface staining with anti-C1, anti-C2 or anti-E1. Direct immunostaining using anti-C2 could not detect intracellular HCV antigens, after 1 h of incubation with the virus, while after 24 h of incubation, 28% of infected cells showed positive staining. Only plus strand RNA was detectable intracellularly as early as 1 h after incubation, and remained detectable throughout 48 h post-infection.Interestingly, minus RNA strand could not be detected after 1 h, but became strongly detectable intracellularly after 24 h post-infection.CONCLUSION: Monocytes and lymphocytes are the preferred target cells for HCV infection in peripheral blood leukocytes. Our specific anti-core and anti-E1 antibodies are valuable reagents for demonstration of HCV cell cycle.Also, HCV is capable of infecting and replicating in peripheral blood mononuclear cells as confirmed by detection of minus strand HCV RNA as well as intracellular staining of core HCV antigen. | Mostafa K El-Awady Ashraf A Tabll El-Rashdy M Redwan Samar Youssef Moataza H Omran Fouad Thakeb Maha El-Demellawy | 2005 | World Journal of Gastroenterology2005，11，33： | 4 |
| 3 | HepG2 cells support viral replication and gene expression of hepatitis C virus genotype 4 in vitro显示文摘瞄准:与丙肝的长期的复制建立一个房间文化系统病毒(HCV ) 染色体和病毒的抗原的表示在试管内。方法:HepG2 房间线被孵化与长期的丙肝从一个病人与浆液为它的危险性测试到 HCV。房间和上层清液在文化期间在各种各样的时间点被收获。文化上层清液为它感染天真的房间的能力被测试。存在减(反感觉) 在房间的核心和 E1 抗原的 RNA 海滨,和察觉被 RT-PCR 和免疫学的技术(流动血细胞计数和西方的污点) 分别地检验。结果:细胞内部的 HCV RNA 首先在 d 上被检测 3 在感染以后然后能一致地在至少三个月的一个时期上在房间和上层清液被检测。新鲜房间能从有教养的感染的房间感染上层清液。流动 cytometric 分析证明表面和在房子里使用的细胞内部的 HCV 抗原表示使 polyclonal 成为了抗体(反核心,和 anti-E1 ) 。西方的污点分析证明在分子量的产生免疫性的肽的簇的表示在一个月内在 31 和 45 kDa 之间延长了感染的房间的旧文化而这簇在 uninfected HepG2 房间是无法发现的。结论:HepG2 房间线产生 HCV 感染而且支持它的复制在试管内不仅。HCV 结构的蛋白质的表示能在感染的 HepG2 房间被检测。这些房间也能够流病毒的粒子进接着对 uninfected 房间变得传染的培养基。 | Mostafa K El-Awady Ashraf A Tabll Yasmine S El-Abd Mahmoud M Bahgat Hussein A Shoeb Samar S Youssef Noha G Bader El Din El-Rashdy M Redwan Maha El-Demellawy Moataza H Omran Wael T El-Garf Said A Goueli | 2006 | World Journal of Gastroenterology2006，12，30： | 2 |
| 4 | Optimal path computation for autono- mous aerial vehicles 显示文摘 | Samar R Kamal W A | 2012 | Cognitive Computation2012，4，4： | 1 |
| 5 | Prediction of some cotton fiber blends properties using regression models显示文摘 | MOHAMED N SAMAR A E | 2008 | Al- exandria Engineering Journal2008，47，2： | 1 |
| 6 | Wavelet analysis of neuroelectric waveforms:A conceptual tutorial显示文摘 | Samar V J Bopardikar A Rao R | | 0，，01： | 1 |
| 7 | Cardiac and renal effects of omapatrilat,a vasopeptidase inhibitor,in rats with experimental congestive heart failure显示文摘 | Abassi Zaid A Yahia Ali Zeid Samar | 2005 | Am J Physiol Heart Circ Physiol2005，288，： | 1 |
| 8 | Detection and identifi-cation of non-tuberculous mycobacterial infections in 6,472 tubercu- losis suspected patients显示文摘 | Bahrmand A R Madani H Samar G | 1996 | Seand J Infect Dis1996，28，： | 1 |
| 9 | Optimal path computation for autonomous aerial vehicles显示文摘 | SAMAR R KAMAL W A | 2012 | Cognitive Computation2012，4，4： | 1 |
| 10 | Wavelet analysis of neuroelectric waveforms: a conceptual tutorial 显示文摘 | Samar V J Bopardikar A Rao R | 1999 | Brain Lang1999，66，1： | 1 |
| 11 | Bioavailability en- hancement of verapamil HC1 via intranasal chitosan microspheres 显示文摘 | Mamdouh A M Noha M Z Samar M | 2014 | Eur J Pharm Sci2014，51，： | 1 |
| 12 | Nanocrystalline calcium phosphate ceramics in biomedical engineering显示文摘 | SAMAR J K ABHILASHA B HIMESH A B | 2007 | Materials Science and Engineering C2007，27，： | 1 |
| 13 | Optimal path computation for autonomous aerial vehicles显示文摘 | SAMAR R KAMAL W A | 2012 | Cognitive Computation2012，4，4： | 1 |
| 14 | Extraction of cobalt and lead from waste water using a liquid surfac- tant membrane emulsion显示文摘 | Bourenane S Samar M E H Abbaci A | 2003 | Acta Chimica Slovenica2003，50，4： | 1 |
| 15 | Successful use of linezolid in the treatment of enterococcal endocarditis: an effective and safe option? 显示文摘 | Javaid M Abdelhamed A Samar H | 2008 | Clinical Microbiology Newsletter2008，30，1： | 1 |
| 16 | File and Replication in Data Grids 显示文摘 | H Stockinger A Samar B Allcock | 2002 | Journal of Cluster Computing2002，5，3： | 1 |
| 17 | File and object replication in data grids显示文摘 | Stockinger H Samar A Allcock B | 2002 | Journal of Cluster Compu-ting2002，5，3： | 1 |
| 18 | File and object replication in data grids显示文摘 | Samar A Allcock B | 2002 | Journal of Cluster Computing2002，5，3： | 1 |
| 19 | Predictors of chronic idiopathic thrombocytopenic purpura显示文摘 | Mohssen E Samar F Abeer A | 2010 | Pediatr Blood Cancer2010，54，： | 1 |
| 20 | Wavelet analysis of neuroelectric waveforms:a conceptual tutorial显示文摘 | Samar VJ Bopardikar A Rao R | 1999 | Brain Lang1999，66，1： | 1 |
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