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| 1 | Experimental study on antitumor effect of arsenic trioxide in combination with cisplatin or doxorubicin on hepatocellular carcinoma显示文摘INTRODUCTIONThe main component of a traditional Chinese drug 'Pishuang'. arsenic trioxide (As2O3), has obviously selective anti-tumor effect on human hepatocellular carcinoma (HCC)in both in vitro and in vivo studies[1-5]. Due to limited effectiveness when any anti-carcinogen is used alone and obviously increased toxicity when the dose is raised, there is no exception for As2O3. Furthermore, combined chemotherapy contributes to improve therapeutic effectiveness, disperse toxicity and surmount drug-resistance,in which the combination of traditional Chinese and modern medicine has more advantages and characteristics. As a result,we made an experimental study on anti-tumor effect of As2O3in combination with cisplantin (PDD) or doxorubicin (ADM)on HCC. to investigate the possibility of AS2O3 in combination with PDD or ADM and nature of interaction between them,and to provide experimental basis for clinical application. | Wei Wang~1 Shu-Kui Qin~1 Bao-An Chen~2 Hui-Ying Chen~1 1 Chinese PLA Cancer Center,Chinese PLA 81 Hospital,Nanjing 210002,Jiangshu Province,China2 Affliliated Zhongda Hospital of Southeast University Medical College,Nanjing 210087,Jiangsu Province,China | 2001 | World Journal of Gastroenterology2001，7，5： | 50 |
| 2 | SYNTHESIS OF INTERMETALLICS BY MECHANICAL ALLOYING显示文摘SYNTHESISOFINTERMETALLICSBYMECHANICALALLOYINGF.H.(Sam)Froes;C.Suryanarayana;andD.Mukhopadhyay(InstituteforMaterialsandAdvance... | F. H.(Sam) Froes C. Suryanarayana and D. Mukhopadhyay (Institute for Materials and Advanced Processes (IMAP), University of Idaho,Moscow, ID 83844-3026, USA)C-G. Li(BlM, P.O. Box 81 , Beijing, 100095, P.R. CHINA)K. Brand(On leave from Institut fur Werkst | 1995 | Acta Metallurgica Sinica(English Letters)1995，8，Z1： | 10 |
| 3 | “地壳异常压力”学术研讨会显示文摘延用至今的地质作用深度测算方法 ,即重力 /密度法 ,是基于“地下岩石处于静水压力状态” (Heim,1978)和“地下某一深处的垂直压力等于上覆岩石柱的总重量” (ДИННИК,1937)两个理论假设。下面刊登的是“地壳异常压力学术研讨会”专家们的发言 (北京 ,2 0 0 0 . 2 )。到会专家对上述假设和测算方法提出了不同见解 ,指出 ,浅部地壳直至地幔深处的岩石都是固体状态 ,地下的压力是极不均匀的 ,所以对地壳中的地质作用深度的测算必须把所处岩石看作固体 ,并依据固体物理理论 ,也就是说 ,除重力之外 ,构造力、瞬时压力、结晶力、变质作用、岩石相变等都会产生局部巨大的异常压力。因此 ,应该对地壳异常压力进行深入研究以建立更具普适性的深度测算公式。专家们还认为 ,对在全球具有重要地位的大别超高压变质带的形成深度 ,我国科学家认为是 32 km左右 ,属壳内成因 ,并提供了测算数据 ,但该项研究还应深化。 | CHEN Qing-xuan,REN Xi-fei,LU Gu-xian: ( Institute of Geomechanics,CAGS,Beijing 1 0 0 0 81 ,China) ( 2 ) DONG Shen-bao,LIU Rui-xun,CHEN Jing: ( Departmentof Geology,Peking University,Beijing 1 0 0 871 ,China) ( 3 ) WANG Fang-zheng:( Chinese University of Geosciences,Wuhan 4 3 0 0 74 ,China) ( 4) REN Ji-shun,LITing-dong,LIU Dun-yi: ( Institute of Geology,CAGS,Beijing 1 0 0 0 3 7,China) ( 5) ZHAIYu-sheng:( Chinese University of Geosciences,Beijing1 0 0 0 83 ,China) ( 6) ZHANG Bing-xi:( Ministry of Land and Resources,Beijing1 0 0 0 3 5,China) ( 7) SHAO Li-qin:( Ministry of Science and Technology,Beijing 1 0 0 0 3 8,China) | 2000 | 地质力学学报2000，6，3： | 6 |
| 4 | The Relationships between cyclin D1 Expression and Prognosis of Non-small Cell Lung Cancer显示文摘Background and objective cyclin D1 is a member of the cyclin family,and it has been proven that it plaied an important role in tumorigenesis,invasion and metastasis.We performed a retrospective study on the cyclin D1 expression in non-small cell lung cancer (NSCLC) according to the clinical characteristics.Methods One hundred fifteen postsurgical NSCLC patients were investigated.Immunohistochemistry was used to evaluate the cyclin D1 expression.Results Overall survival was significantly lower in patients with cyclin D1-high expression of tumors than those with cyclin D1 low expression of tumors (χ2=5.132,P=0.023).In early stage patients (stage I,II),the overall survival was significantly lower in patients with cyclin D1-high expression of tumors than those with cyclin D1-low expression of tumors (χ2=6.863,P=0.009).cyclin D1 status (hazard ratio=0.630;P=0.035),differentiation (hazard ratio=0.399;P<0.001),and pTNM (hazard ratio=1.576;P<0.001) to be independent prognostic factors for NSCLC patients.Specifically,the cyclin D1 status (hazard ratio=0.188;P=0.008) was a significant prognostic factor for patients with stage I NSCLCs.Conclusion cyclin D1 expression is an independent prognosis factor for postoperative patient in stage I,II NSCLCs. | Jiping ZHU1,Like YU1,Ping ZHAN2,Yong SONG2,Qin WANG3 1Department of Respiratory Medicine,Nanjing Chest Hospital,Nanjing 210029,China 2Department of Respiratory Medicine,Jinling Hospital,Nanjing University School of Medicine,Nanjing 210001,China 3Department of Respiratory Medicine,81 Hospital of PLA,Nanjing 210002,China | 2010 | 中国肺癌杂志2010，13，8： | 3 |
| 5 | A NOTE ON THE MAXIMUM GENUS OF 3-EDGE-CONNECTED NONSIMPLE GRAPHS显示文摘Let G be a 3 edge connected graph (possibly with multiple edges or loops), and let γ M(G) and β(G) be the maximum genus and the Betti number of G, respectively. Then γ M(G)≥β(G)/3 can be proved and this answers a question posed by Chen, et al. in 1996.F FIRST | Huang YuanqiuDept.of Math.,Hunan Normal Univ.,Changsha 41 0 0 81 . Email:hyqq @public.cs.hn.cn | 2000 | Applied Mathematics(A Journal of Chinese Universities)2000，15，3： | 2 |
| 6 | Systemic inflammation exacerbates behavioral and histopathological consequences of isolated traumatic brain injury in rats显示文摘 | Utagawa A Truettner JS Dietrich WD et 81 | 2008 | Exp Neurol2008，211，1： | 1 |
| 7 | Preoperative diagnosis of cervical metastatic lymph nodes in papillary thyroid carcinoma: comparison of ultrasound, computed tomography, and combined ultrasound with computed tomography显示文摘 | Kim E Park JS Son KR et 81 | 2008 | Thyroid2008，18，4： | 1 |
| 8 | Application of Supercon- ducting Magnetic Bear/ngs to a lOkWh-Class Flywheel Energy Storage System显示文摘 | lchihara T Matsunaga K Kita M et 81 | 2005 | IEEE Transactions on Applied Superconductiv- ity2005，6，15： | 1 |
| 9 | HepatoceUular o11- eofetal protein,glypiean 3 is a sensitive marker for alpha - feto- protein - producing gastric carcinoma 显示文摘 | Hishinuma M Ohashi KI Yamauehi N et 81 | 2006 | Histopathalogy2006，49，5： | 1 |
| 10 | Prevalence of diabetes among men and women in China显示文摘 | Yang W Lu J Weng J et 81 | 2010 | N Engl J Med2010，362，12： | 1 |
| 11 | Comparing convention- al gauze therapy to vacuum - assisted closure wound therapy显示文摘 | Moues CM van den Bemd GJ Heule F et 81 | 2007 | J Plast Recons: Aesthet Stag2007，60，： | 1 |
| 12 | Removal of carbon and nutri- ents from domestic wastewater using a low investment,integrated treatment concept 显示文摘 | Aiyuk S Amoako J Raskin L et 81 | 2004 | Water Research2004，38，13： | 1 |
| 13 | Antibody levels to hepatitis E virus in North Carolina swine workers,non-swine work-ers,swine,and mufids显示文摘 | Withers-M-K Correa-M-T Morrow-M et 81 | | 0，，04： | 1 |
| 14 | Pharmacokinetics of plantamajoside and acte- oside from Plantago asiatica in rats by liquid chromatography - mass spectrometry 显示文摘 | Li Y Gan L Li GQ et 81 | 2014 | J Pharm Biomed Anal2014，89，： | 1 |
| 15 | Low-cost thermo-op- tic imaging sensors:A detection principle based on tunable one- dimensional photonic crystals 显示文摘 | Exner A T Pavlichenko I Lotsch B V et 81 | 2013 | ACS Applied Materials & In- terfaces2013，5，5： | 1 |
| 16 | Multiplicity of positive periodic solutions to second order differential equations 显示文摘 | CHU J F LIN X N JIANG D Q et 81 | 2006 | Bulletin of the Aus- tralian Mathematical Society2006，73，2： | 1 |
| 17 | Biomechanical analysis of pos- teromedial tibial plateau split fracture fixation 显示文摘 | Zeng ZM Luo CF Pulnis S et 81 | 2011 | Knee2011，18，1： | 1 |
| 18 | Type1/Type2 cytokine paradigm and the progression of pulmonary fibrosis 显示文摘 | Lukacs N W Hogaboam C Chensue S W et 81 | 2001 | Chest2001，120，1： | 1 |
| 19 | The analysis of the fine specificity of celiac disease antibodies using tissue transglutaminase fragments 显示文摘 | SBLATTERO D FLORIAN F AZZONI E et 81 | 2002 | Eur J Biochem2002，269，21： | 1 |
| 20 | Quantification of rabeprazole in human plasma by liquid chromatography-tandem mass spectrometry 显示文摘 | Zhang Y Oaen XY C u Q et 81 | 2004 | Anal Chim Aeta2004，523，2： | 1 |
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