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| 1 | 2001~2010年体育改革与发展纲要显示文摘为实现我国的现代化建设目标 ,充分发挥体育在提高人民物质文化生活中的作用。国家体育总局经过充分调研 ,经过 1999年、2 0 0 0年全国体育工作会议修改 ,制定《2 0 0 1~ 2 0 10年体育改革与发展纲要》,纲要明确了 2 1世纪前10年我国体育的指导思想、基本战略和奋斗目标。提出 :10年内 ,大众体育普及程度明显提高 ,体育人口达总人口的40 %左右 ;竞技体育保持亚洲领先 ,夏季奥运会前列 ,实现冬季奥运会零的突破 ;体育产业初具规模等。《纲要》是我国体育今后 | The State Sport General Administration (December 15,2000) | 2001 | 体育科学2001，21，3： | 147 |
| 2 | 我国不同胎龄新生儿体格发育的现状显示文摘我国对不同胎龄新生儿体格发育的研究,始于1980年上海市对20,884例新生儿出生体重的回顾性分析,列出了孕32~34周不同胎龄新生儿体重的百分位数。1983年发表了江苏省5市13所医院于1980~1981年调查的14。 | 中国15城市新生儿体格发育科研协作组 | 1991 | 临床儿科杂志1991，9，2： | 34 |
| 3 | Effects of aminoguanidine on nitric oxide production induced by inflammatory cytokines and endotoxin in cultured rat hepatocytes显示文摘AIM To study the effects of aminoguanidine(AG) and two L-arginine analogues Nω-nitro-L-arginine methyl ester (L-NAME) and Nω-nitro-L-arginine (L-NNA) on nitric oxide (NO) productioninduced by cytokines (TNF-α, IL-11β, and IFN-γ)and bacterial lipopolysaccharide (LPS) mixture(CM) in the cultured rat hepatocytes, andexamine their mechanisms action.METHODS Rat hepatocytes were incubatedwith AG, L-NAME, L-NNA, Actinomycin D (ActD)and dexamethasene in a medium containing CM(LPS plus TNF-α, IL-1β, and IFN-γ) for 24 h. NOproduction in the cultured supernatant wasmeasured with the Griese reaction. IntracellularcGMP level was detected with radioimmunoasey.RESULTS NO production was markedlyblocked by AG and L-NAME in a dose-dependentmanner under inflammatory stimuli conditiontriggered by CM in vitro. The rate of themaximum inhibitory effects of L-NAME (38.9%)was less potent than that obtained with AG(53.7%, P<0.05). There was no significantdifference between the inhibitory effects of AGand two L-arginine analogues on intracellularcGMP accumulation in rat cultured hepatocytes.Non-specific NOS expression inhibitordexamethasone ( DEX ) and iNOS mRNAtranscriptional inhibitor ActD also significantlyinhibited CM-induced NO production. AG(0.1mmol.L-1) and ActD (0.2ng@Lt) wereequipotent in decreasing NO production inducedby inflammatory stimuli in vitro, and botheffects were more potent than that induced bynon-selectivity NOS activity inhibitor L-NAME(0. 1 mmol@ L- 1) under similar stimuli conditions(P | Guo Liang Zhang Ye Hong Wang Hui Ling Teng Zhi Bin Lin Department of Pharmacology,School of Basic Medical Sciences,Beijing University,Beijiog 100083,ChinaDr.Guo Liang Zhang graduated from Xinxiang Medical College in 1982,got Ph.D.at Nagoya City University Medical School,Japan in 1994,finished postdoctoral research at Beijing Medical Univcrsity in 1996,now an associate professor of pharmacology,specialized in hepatic pharmacology,having 15 papers published. | 2001 | World Journal of Gastroenterology2001，7，3： | 20 |
| 4 | Virulence and potential pathogenicity of coccoid Helicobacter pylori induced by antibiotics显示文摘AIM To explore the virulence and the potential pathogenicity of coccoid Helicobacter pylori (H. pylori) transformed from spiral form by exposure to antibiotic.METHODS Three strains of H. pylori, isolated from gastric biopsy specimens of confirmed peptic ulcer, were converted from spiral into coccoid from by exposure to metronidazole.Both spiral and coccoid form of H. pylori were tested for the urease activity, the adherence to Hep-2 cells and the vacuolating cytotoxicity to Hela cells, and the differences of the protein were analysed by SDS-PAGE and Western blot,The mutation of the genes including ureA, ureB,hpaA; vacA and cagA, related with virulence,was detected by means of PCR and PCR-SSCP.RESULTS In the coccoid H. pylori, the urease activity, the adherence to Hep-2 cells and the vacuolating cytotoxicity to Hela cells alldecreased. In strain F44, the rate and index of adherence reduced from 70.0% ± 5.3% to 33% ±5.1% and from 2.6 ±0.4 to 0.96 ±0.3 (P<0.01),respectively. The invasion of coccoid H. pylori into Hep-2 cell could be seen under electronmicroscope. SDS-PAGE showed that the content of the protein with the molecular weight over Mr74 000 decreased, and the hybriditional signal in band Mr 125 000 weakened, while the band Mr 110000 and Mr63000 strengthened in coccoid H. pylori as shown in Western blot. The results of PCR were all positive, and PCR-SSCP indicated that there may exist the point mutation in gene hpaA or vacA.CONCLUSION The virulence and the proteins with molecular weight over Mr74 000 in coccoid H. pylori decrease, but no deletion exists in amplification fragments from ureA, ureB, hpaA,vacA and cagA genes, suggesting that coccoid H. pylori may have potential pathogenicity. | Fei Fei She1 Dong Hui Su1 Jian Yin Lin2 Lin Ying Zhou3 1Department of Microbiology, Fujian Medical University. Fuzhou 350004, Fujian Province, China2Department of Molecular Medicine, Fujian Medical University, Fuzhou 350004, Fujian Province, China 3Laboratory of Electron Microscope, Fujian Medical University, Fuzhou 350004. Fujian Province. ChinaFei Fei She. graduated from Fujian Medical University as a postgraduate in 1991, now associate professor of microbiology and immunology, specialized in molecular biology of pathogen, having 15 papers published. | 2001 | World Journal of Gastroenterology2001，7，2： | 18 |
| 5 | 新疆望峰金矿成矿流体研究及其成因意义显示文摘新疆望峰金矿,产于中天山结晶基底中的韧性剪切带内。围岩蚀变和流体包裹体研究表明,成矿过程包括了3个阶段,从早到晚有石英黄铁矿阶段、多金属硫化物阶段和石英碳酸盐阶段,温度分别集中在360~520℃、240~360℃和120~240℃;矿化以第Ⅱ阶段为主。成矿流体的δ18O值变化于1.15‰~2.70‰之间,属于变质热液与大气降水热液的混合流体。包裹体成分表明成矿流体来源较浅,但有利于金矿化;CO2/H2O比值多大于0.026,也有利于成矿。而包裹体捕获压力表明成矿作用发生在5.6~1.2km深度范围,主要发生在1.9km左右;矿化过程与地壳抬升伸展的过程一致,自然亦与碰撞造山体制的矿化规律一致。因此,古生代末期的碰撞造山作用导致了望峰金矿的形成,冰达坂断裂两侧是寻找望峰式金矿的有利地带。石英红外光谱分析表明,CO2光密度(D2)及其与H2O光密度(D1)的比值(D2/D1)普遍较高,指示矿化较强;D2>0.55和D2/D10.26是该区富金样品的标志。 | Chen Yanjing 1) Li Xin 1) Jing Jun 2) Gao Xiuli 1) Chen Huayong 1) Wu Xidan 2) Wu Dehua 2) ( 1) Department of Geology, Peking University 2)Team 15 of Gold Headquarters, MMIC, Urumqi ) | 1998 | 地球学报(中国地质科学院院报)1998，19，2： | 18 |
| 6 | 1994年陕北地区淤地坝水毁情况调查显示文摘1994年7、8月间,陕北不少地方遭受特大暴雨袭击,一大批淤地坝和水库被洪水冲坏,一些库坝出现险情。经陕西省水利厅及有关人员深入灾区进行调查,这次被洪水冲垮和局部冲坏的淤地坝共7000多座,冲毁坝地3200hm2,给群众生产、生活带来一定困难。但淤地坝在暴雨洪水中也发挥了抗洪、拦泥、淤地作用,新淤坝地4000多公顷,扣除水毁坝地后,又新增坝地1200多公顷。文中就水毁原因进行了分析,并对今后搞好淤地坝工作提出了一些意见。 | Silt Arrester Investigation Team of Shannxi Water and Soil Conservation Bureau(Shannxi Water and Soil Conservation Bureau, Xi’an,710004)(15) | 1995 | 人民黄河1995，17，1： | 12 |
| 7 | The 3-D non-axisymmetrical Lamb's problem in transversely isotropic saturated poroelastic media显示文摘Based on Biots theory on fluid-saturated porous media, the displacement functions are adopted to convert the 3-D Biots wave equations in the cylindrical coordinate for transversely isotropic saturated poroelastic media into two棗one 6-order and one 2-order棗uncoupling differential governing equations. Then, the differential equations are solved by the Fourier expanding and Hankel integral transform method. Integral solutions of soil skeleton displacements and pore pressure as well as the total stresses for poroelastic media are obtained. Furthermore, the systematic study on Lambs problems for the transversely isotropic saturated poroelastic media is performed. Integral solutions for surface radial, vertical and circumferential displacements are obtained in both cases of drained surface and undrained surface under the vertical and horizontal harmonic excitation force. In the end of this paper, the numerical examples are presented. The calculation results indicate that the difference between the model of isotropic saturated poroelastic media and that of transversely isotropic saturated poroelastic media is obvious. | HUANG Yi1 & WANG Xiaogang1,2 1. School of Civil Engineering, Xian University of Architecture & Technology, Xian 710055, China 2. Department of Civil Engineering, Qinghai University, Xining 810016, China Correspondence should be addressed to Huang Yi (email: huangyih@pub.xaonline.com) Received April 15, 2004 revised July 12, 2004 | 2004 | Science China(Technological Sciences)2004，47，5： | 10 |
| 8 | Influence of Long-Term Fertilization with Different Mineral Fertilizers and Farmyard Manure on Some Soil Chemical Properties and Crop Yields显示文摘Longtermexperimentshaveaspecialvalueforprovidinginformationtoguideagriculturaldevelopments.Asearlyasin1843,LawesandGilbertes... | LIU DEHUI 1, J. LABETOWICZ 2 and L. KUSZELEWSKI 2 1 Nanjing Agricultural University, Nanjing 210095 (China) 2 Department of Agricultural Chemistry, Warsaw Agricultural University, Warsaw 02 528 (Poland) (Received February 15, 1998 r | 1998 | Pedosphere1998，8，3： | 8 |
| 9 | NUMERICAL STUDIES ON RESONANT AND ENHANCEMENT EFFECTS FOR COUPLING OF MICROWAVE PULSES INTO NARROW SLOTS显示文摘In this paper, modifications to the finite-difference time-domain(FD-TD) method for modeling microwave pulse coupling into a slot, which is much narrower than one conventional FD-TD cell, are discussed. The coupling process of microwave pulse into a slot is studied by using the modified FD-TD method, and the dependence of microwave coupling on slot sizes, the carrier frequencies and the polarization directions of the incident waves is analysed. Resonant and enhancement effects which occur in this process are observed. The condition at which the resonant effect takes place is also presented. | Wang Jianguo Yu Hanqing Liu Guozhi Chen Yusheng Fan Ruyu (Northwest Institute of Nuclear Technology, Branch 15, P. O. Box 69, Xi’an 710024)Ge Debiao(Department of Physics, Xidian University, Xi’an 710071) | 1998 | Journal of Electronics(China)1998，15，2： | 6 |
| 10 | Molecular epigenetics: dawn of a new era of biomedical research显示文摘At about the same time in 1940s when Erwin Schrdinger published his famous little book What Is Life, which sparked the birth of molecular biology, the term epigenetics was coined by the English biologist Conrad Waddington. The concept of epi-inheritance can be traced back to French naturalist Jean-Baptiste Lamarck’s idea of 'inheritance | XU Rui-Ming Institute of Biophysics, Chinese Academy of Sciences 15 Datun Road, Chaoyang District, Beijing 100101, China | 2009 | Science China(Life Sciences)2009，52，4： | 5 |
| 11 | FLOW MECHANISMS ANDSEDIMENT TRANSPORT IN COMPOUND CHANNELS显示文摘Recent work on the UK Flood Channel Facility (FCF) is described. An overview of tile various experimental programmes. involving overbank flow studies in straight. skewed and meandering channels. is given. Some key results concerning flow mechanisms. resistance. dispcrsion and sediment transport are reviewed. A summary of different methods for estimating the stage-discharge relationship for overbank flows is included. An extensive bibliography is given for those seeking more detailed information. | Donald W. KNIGHT (1 School of Civil Engineering. The University of Birmingham, Edgbaston, Birmingham, B 15 2TT. UK) | 1999 | International Journal of Sediment Research1999，14，2： | 4 |
| 12 | Intrinsic peroxidase-like activity of ferromagnetic nanoparticles and its application in immunoassay and environment treatment显示文摘Nanoparticles that contain magnetic materials, such as magnetite (Fe3O4), are particularly useful for imaging and separation techniques. Since these nanoparticles are | Lizeng Gao, Jie Zhuang, Xiyun Yan National Laboratory of Biomacromolecules and Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China. | 2009 | 生物物理学报2009，25，S1： | 3 |
| 13 | 我国15城市不同胎龄新生儿体格发育调查研究[J]显示文摘 | 中国15城市新生儿体格发育科研协作组 | | 中华儿科杂志0，，： | 2 |
| 14 | Novel ^(99m)Tc labeled σ r eceptor ligand as a potential tumorimaging agent显示文摘A novel 99mTc labeled complex, [N-[2-((2-oxo-2-(4-(3-phenylpropyl)piperazin-1-yl)ethyl) (2-mercaptoethyl)amino)acetyl]-2-aminoethanethiolato]Technetium(V) oxide (PPPE-MAMA′-99mTcO) ([99mTc]-2) has been designed and prepared based on the integrated approach. The corresponding rhenium complex (PPPE-MAMA′-ReO)(Re-2) has been prepared and characterized. In vitro competi-tion binding assays show moderate affinity of Re-2 towards σ1 and σ2 receptors with Ki values of 8.67 ± 0.07 and 5.71 ± 1.88 μmol, respectively. Planar images obtained at 0.5 h, 4 h, 20 h after i.v. in-jection indicate the accumulation of [99mTc]-2 in MCF-7 human breast tumor bearing mice at 20 h. Furthermore, the accumulation of [99mTc]-2 has been inhibited at 20 h after co-injection of [99mTc]-2 plus haloperidol (1 mg/kg). Biodistribution studies of [99mTc]-2 display an in vivo tumor uptake of 0.14% ± 0.01% ID/g at 24 h post i.v. injection with a tumor/muscle ratio of 6.02 ± 0.87. The above results suggest that [99mTc]-2, derived from a previously published lead compound, retains certain tumor uptake and affinity for σ receptors. [99mTc]-2 may be used as a basis for further structural modifications to develop tumor imaging agents with high affinity for σ receptors. | FAN Caiyun1, JIA Hongmei1, Deuther-Conrad Winnie2, Brust Peter2, Steinbach J?rg2 & LIU Boli1 1. Key Laboratory of Radiopharmaceuticals (Beijing Normal University), Ministry of Education, Department of Chemistry, Beijing Normal University, Beijing 100875, China 2. Institute of Interdisciplinary Isotope Research, Permoserstr. 15, 04318 Leipzig, Germany Correspondence should be addressed to Liu Boli | 2006 | Science China Chemistry2006，49，2： | 2 |
| 15 | 武汉市基层社会治理创新:经验、问题及对策显示文摘基层是社会治理的基础性场域,理论与实践皆表明,加强以政府为主导、社会组织和人民群众广泛参与的主体多元化的'社会共治',是推进和创新基层社会治理的必由之路。本文试图在梳理武汉市各街区近年来形成的有代表性的社会治理创新经验,以及分析仍存在的问题基础上,就如何进一步构建'社会共治'格局提出若干政策建议。 | 中共武汉市委党校第15期街道(乡镇)党政正职领导干部进修班课题组 刘华珍 | 2017 | 长江论坛2017，0，1： | 2 |
| 16 | Benigncongenitalmusculardystrophywithantosomaldominantheredity:Problemsofclaassification显示文摘 | 〔15〕SchmalbruchH KamienieckaI FuglsangF etal | 1987 | JNeurol1987，234，： | 1 |
| 17 | ISF-SiO2An Efficient Reagent System for the One-pot Synthesis of 1,2,4,5-tetrasubstituted Imidazoles 显示文摘 | SADEGHI B MIRJALIL 15 B F HASHEMI M M | 2008 | Tetrahedron Lett2008，49，： | 1 |
| 18 | 显示文摘 | 张连启.? 医院电子档案的管理与利用措施分析(J)华章. 2013 (15) | 2013 | 华章2013，，： | 1 |
| 19 | Overexpression of Cdx2 inhibits progression of gastric cancer in vitro显示文摘 | Xie Y 15 L Wang X | 2010 | Int J Oncol2010，36，2： | 1 |
| 20 | Resorption of a calcium hydroxide/iodoform paste (Vitapex) in root canal therapy for primary teeth:a case report显示文摘 | 15 Nurko C Ranly DM Garcia-Godoy F | 2000 | Pediatr Dent2000，22，6： | 1 |
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