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| 1 | Recent advances in the management of hemorrhoids显示文摘Hemorrhoids are considered one of the most common anorectal diseases with a prevalence of 4.4% up to 36.4% of the general population, and a peak incidence between 45 and 65 years. Hemorrhoidal disease presents with a prolapsed lump, painless bleeding, discomfort, discharge, hygiene problems, soiling, and pruritus. Sliding anal canal lining theory is the most accepted theory as a cause of hemorrhoidal disease; however, it is also associated with hyper-vascularity, and, recently, with several enzymes or mediators involved in the disintegration of the tissues supporting the anal cushions, such as matrix metalloproteinase. A comprehensive search in published English-language literature till 2013 involving hemorrhoids was performed to construct this review article, which discusses advances in the management of hemorrhoids. This includes conservative treatment(life style modification, oral medications, and topical treatment), office procedures(rubber band ligation, injection sclerotherapy, infrared and radiofrequency coagulation, bipolar diathermy and direct-current electrotherapy, cryosurgery, and laser therapy), as well as surgical procedures including diathermy hemorrhoidectomy, Liga Sure hemorrhoidectomy, Harmonic scalpel hemorrhoidectomy, hemorrhoidal artery ligation, stapled hemorrhoidopexy(SH), and double SH. Results, merits and demerits of the different modalities of treatment of hemorrhoids are presented, in addition to the cost of the recent innovations. | Mahmoud Sakr Khaled Saed | 2014 | World Journal of Surgical Procedures2014，4，3： | 2 |
| 2 | New approaches in laparoscopic surgery for colorectal diseases: The totally laparoscopic and single-incision approaches显示文摘More than 20 years have passed since the first report of laparoscopic colectomy in 1991. Thereafter, laparoscopic surgery for the management of colorectal diseases has been widely accepted as a prevailing option because of improved cosmetic outcomes, less postoperative pain, and shorter hospital stay in comparison with open surgery. To further the principle of minimally invasive surgery, two new approaches have been developed in this rapidly evolving field. The first is the totally laparoscopic approach. Currently most of standard techniques inevitably involve an abdominalincision for retrieval of the specimen and preparation for anastomosis, which might compromise the benefits of laparoscopic surgery. The totally laparoscopic approach dispenses with this incision by combining completely intraperitoneal anastomosis with retrieval of the specimen via a natural orifice, such as the anus or the vagina. Our new and reliable technique for intraperitoneal anastomosis is also described in detail in this article. The second is the single-incision approach. While three to six ports are needed in standard laparoscopic surgery, the single-incision approach uses the umbilicus as the sole access to the abdominal cavity. All of the laparoscopic procedures are performed entirely through the umbilicus, in which the surgical scar eventually becomes hidden, achieving virtually scarless surgery. This article reviews the current status of these two approaches and discusses the future of minimally invasive surgery for colorectal diseases. | Hiroki Akamatsu Masahiro Tanemura Kentaro Kishi Mitsuyoshi Tei Toru Masuzawa Masaki Wakasugi | 2015 | World Journal of Surgical Procedures2015，5，1： | 2 |
| 3 | Should multi-gene panel testing replace limited BRCA1/2 testing? A review of genetic testing for hereditary breast and ovarian cancers显示文摘Clinical testing of patients for hereditary breast and ovarian cancer syndromes began in the mid-1990s with the identification of the BRCA1 and BRCA2 genes.Since then,mutations in dozens of other genes have been correlated to increased breast,ovarian,and other cancer risk.The following decades of data collection and patient advocacy allowed for improvements in medical,legal,social,and ethical advances in genetic testing.Technological advances have made it possible to sequence multiple genes at once in a panel to give patients a more thorough evaluation of their personal cancer risk.Panel testing increases the detection of mutations that lead to increased risk of breast,ovarian,and other cancers and can better guide individualized screening measures compared to limited BRCA testing alone.At the same time,multi-gene panel testing is more time-and cost-efficient.While the clinical application of panel testing is in its infancy,many problems arise such as lack of guidelines for management of newly identified gene mutations,high rates of variants of uncertain significance,and limited ability to screen for some cancers.Through on-going concerted efforts of pooled data collection and analysis,it is likely that the benefits of multi-gene panel testing will outweigh the risks in the near future. | Nimmi S Kapoor Kimberly C Banks | 2016 | World Journal of Surgical Procedures2016，6，1： | 2 |
| 4 | l,aparoscopie Ioal gastrec- tomy for gastric cancer显示文摘 | Li GX Wang D Hu YF | 2014 | Chinese Journal of Operative Procedures of General Surgery (Electronic Version)2014，11，8： | 1 |
| 5 | Preparation of monomethyl fumarate 显示文摘 | Dymicky M | 1983 | Organic Preparations and Procedures Internotional1983，15，4： | 1 |
| 6 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis 显示文摘 | Huang N E | 1998 | Procedures of the Royal Society of London A1998，454，： | 1 |
| 7 | Convenient synthesis of 5,7-dihydroxy-chromone显示文摘 | GAYLAND F SPENCER A | 1991 | Organic Preparations and Procedures International1991，23，1： | 1 |
| 8 | Preparation of n- monoalkyl maleates and n-mono- and dialkyl fumarates 显示文摘 | Dymicky M Buchanan R L | 1985 | Organic Preparations and Procedures Internotional1985，17，2： | 1 |
| 9 | Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/ relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae 显示文摘 | Takehana A Katsuyama T Yano T | 2002 | Procedure National Academic Sciences USA2002，99，13： | 1 |
| 10 | Collection of Epithelial Cells from Rodent Mammary Gland Via Laser Capture Microdissection Yielding High-Quality RNA Suitable for Microarray Analysis显示文摘 | McGinley JN Zhu ZJ Jiang WQ | 2010 | Bio-logical procedures online2010，12，1： | 1 |
| 11 | Techniques of EMG signal analysis: detection, processing, classification and applications显示文摘 | REAZ M B I HUSSAIN M S MOHDYASIN F | 2006 | Biological Procedures Online2006，8，1： | 1 |
| 12 | Asymmetric synthesis of 2 - ,3 - and 4 -methyl octanoic acids显示文摘 | Philip E Sonnet Joseph Gazzillo | 1990 | Organic preparations and procedures international1990，22，2： | 1 |
| 13 | Thoracoscopic lobectomy is a safe and versatile显示文摘 | Onaitis MW Petersen RP Balderson SS | 2006 | Procedure2006，244，3： | 1 |
| 14 | Preparation of monomethyl fumarate 显示文摘 | Dymicky M | 1983 | Organic Preparations and Procedures International1983，15，4： | 1 |
| 15 | The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis显示文摘 | Huang N E | 1998 | Procedures of the Royal Society of London Series A 454 903-9951998，1998，： | 1 |
| 16 | Ultrasonically accelerated syntheses of furan-2, 4-dicarbaldehyde from 5-hydroxymethyl-2- furfural显示文摘 | Cottier L Descotes G Lewkowski J | 1995 | Organic Preparations and Procedures International1995，27，5： | 1 |
| 17 | Preparation of n-monoalkyl maleates and n-mono-and dialkyl fumarates 显示文摘 | Dymicky M Buchanan R L | 1985 | Organic Preparations and Procedures International1985，17，2： | 1 |
| 18 | An efficient large scale synthesis of nateglinide显示文摘 | Chandrasekhar B Sawanth M S Naik S J | 2004 | Organic Preparations and Procedures International2004，36，5： | 1 |
| 19 | TARTARIC ACID AND ITS O-ACYL DERIVATIVES. PART 2. APPLICATION OF TARTARIC ACID AND OF O-ACYL TARTARIC ACIDS AND ANHYDRIDES. RESOLUTION OF RACEMATES显示文摘 | | 2008 | Organic Preparations and Procedures International2008，，2： | 1 |
| 20 | An efficient oxidation of arylsemicarbazides to the Azn ureas 显示文摘 | Wang C L Wang Y L Wang X | 1998 | Organic Preparations and Procedures International1998，30，1： | 1 |
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