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2371篇 您的检索式:期刊名="Forensic Science"
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1Research progress in the estimation of the postmortem interval by Chinese forensic scholars显示文摘The determination of time since death or the postmortem interval(PMI)is one of the most important and frequently asked questions in forensic medicine.Medicolegal scholars and forensic pathologists around the world have studied the estimation of PMI extensively in the past,and many novel methods and advanced technologies have now been applied in the field.For several centuries,Chinese forensic examiners have also worked on the estimation of the PMI,and there are a large number of excellent studies published in Chinese rather than in English,and these are not easily accessible or known internationally.Therefore we have conducted a review of relevant studies published by Chinese forensic scholars in the last few decades.The scope of this review is to provide a concise summary of the current progress in the estimation of PMI by Chinese forensic researchers using molecular biology,spectroscopic technology,entomological methods,energy changes,thanatochemistry and other methods.Chengzhi Li Qi Wang Yinming Zhang Hancheng Lin Ji Zhang Ping Huang Zhenyuan Wang 2016Forensic Sciences Research2016,1,1:9
2Determination of Electrical Conductivity of Cadaver Skeletal Muscle: A Promising Method for the Estimation of Late Postmortem Interval显示文摘The electrical conductivity(EC)of extracted muscle fluid has been extensively used to evaluate meat freshness and shelf life in the field of food sanitation for decades.The opposite of freshness is the corruption that increases with time.Based on the freshness/corruption principle,we investigated the relationship between long postmortem intervals(PMIs)and EC in cadaver skeletal muscle.EC values of extracted fluid from rat muscles were measured at different PMIs for 10 days.The results indicate that there was a significant correlation between PMI and EC,and the data fit well to the cubic polynomial regression equation y=‑0.01x3+0.264x2‑13.657x+1769.148(R2=0.925).In addition,the EC of different dilutions of these muscle extracts showed strict quadratic correlation(R2=1)with the dilution ratios,suggesting that EC can be measured with very small quantities of muscle sample.Our study suggests that determination of the EC of cadaver skeletal muscle extracts may be a useful method for estimating long PMIs.Zhiyuan Xia Xiandun Zhai Beibei Liu Yaonan Mo 2015Journal of Forensic Science and Medicine2015,1,1:8
3Wastewater analysis for nicotine,cocaine,amphetamines,opioids and cannabis in New York City显示文摘According to current surveys and overdoses data,there is a drug crisis in the USA.Wastewater-based epidemiology(WBE)is an evolving discipline that analyses wastewater samples to detect drugs and metabolites to estimate drug consumption in a certain community.This study demonstrates how drug relative presence could be tracked by testing wastewater,providing real-time results,in different boroughs in New York City throughout 1 year.We developed and fully validated two analytical methods,one for 21 drugs and metabolites,including nicotine,cocaine,amphetamines,opioids and cannabis markers;and another for the normalization factor creatinine.Both methods were performed by liquid chromatography tandem mass spectrometry(LC-MS/MS)using positive electrospray ionization,achieving a limit of quantification of 5–10 ng/L for drugs and metabolites,and 0.01 mg/L for creatinine.These methods were applied to 48 one-time grab wastewater samples collected from six wastewater treatment plants in New York City(Manhattan,The Bronx,Queens and Brooklyn),eight different times throughout 2016,before and after major holidays,including Memorial Day,4th of July,Labour Day and New Year’s.In this study,the drug group normalized concentrations present in the wastewater samples,in decreasing order,were cocaine,nicotine,opioids,cannabis and amphetamines.When looking at individual compounds,the one with the highest normalized concentration was benzoylecgonine(BE),followed by cotinine,morphine and 11-nor-9-carboxy-tetrahydrocannabinol(THCCOOH).To estimate community use,these concentrations were multiplied by the corresponding correction factor,and the most present were THCCOOH,followed by BE,cotinine and morphine.When comparing the treatment plants by drug group(nicotine,cocaine,amphetamines,opioids and cannabis),samples collected from The Bronx had the highest normalized concentrations for nicotine,cocaine and opioids;The Bronx and Manhattan for cannabis;and Manhattan and Queens for amphetamines.In most of the cases,no effect due to holiday was observed.This study provides the first snapshot of drug use in New York City and how that changes between key calendar dates employing wastewater analysis.Nicole Centazzo Bonnie-Marie Frederick Alethea Jacox Shu-Yuan Cheng Marta Concheiro-Guisan 2019Forensic Sciences Research2019,4,2:7
4Sports-related sudden cardiac death due to myocardial diseases on a population from 1-35 years: a multicentre forensic study in Spain显示文摘This is a multicentre forensic study that identifies all sports-related sudden deaths (SRSDs) in young people,due to myocardial diseases (MDs) that occurred in a large area of Spain.The aim of the study is to assess the epidemiology,causes of death,and sport activities associated with these fatalities.This is a retrospective study based on forensic autopsies performed in the provinces of Biscay,Seville,Valencia and in the jurisdiction covered by the National Institute of Toxicology and Forensic Sciences in Madrid (Spain).The retrospective study encompasses from 2010 to 2017.All sudden cardiac deaths (SCDs) in persons 1-35years old were selected.The total number of SCDs were divided into death occurred during exercise (SRSD) and death during rest,sleep or normal activities (non-SRSD).Each of these two groups was subdivided according to the cause of death into MD (primary cardiomyopathies and myocarditis) and non-MD.Clinic-pathological,toxicological and genetic characteristics of SRSD due to MD were analysed.Over the 8-year study period,we identified 645 cases of SCD in the young: 75 SRSD (11.6%) and 570 non-SRSD (88.4%).MD was diagnosed in 33 (44.0%) of the SRSD and in 112 (19.6%) of the non-SRSD cases.All cases of SRSD due to MD were males (mean age (24.0±7.6) years) practicing recreational sports (85%).SRSDs were more frequent in arrhythmogenic cardiomyopathy (ACM) (37%) and hypertrophic cardiomyopathy (HCM) (24%),followed by myocarditis (15%) and idiopathic left ventricular hypertrophy (ILVH) (9%).Only in five cases of SRSD the MD responsible of death (HCM) had been diagnosed in life.Cardiovascular symptoms related to the disease were present in other seven patients (six of them with ACM).Postmortem genetic studies were performed in 15/28 (54%) primary cardiomyopathies with positive results in 12 (80%) cases.The most frequent sports disciplines were football (49%) followed by gymnastics (15%) and running (12%).In Spain,SRSD in young people due to MDs occurs in males who perform a recreational activity.Compared with control group we observed a strong association between MDs and exertion.One in three SRSDs are due to cardiomyopathy,especially ACM,which reinforces the need for preparticipation screening to detect these pathologies in recreational sport athletes.Further studies are warranted to understand the causes and circumstances of sudden death to facilitate the development of preventive strategies.Benito Morentin M.Paz Suárez-Mier Ana Monzó Pilar Molina Joaquín S.Lucena 2019Forensic Sciences Research2019,4,3:6
5Research progress of aconitine toxicity and forensic analysis of aconitine poisoning显示文摘Chinese herbal medicines have been extensively used in China and other countries for cen-turies.Aconitine,a diterpenoid alkaloid extracted from Aconitum plants,has anti-inflamma-tory and analgesic activities,but can also induce severe arrhythmia and neurotoxicity.Aconitine poisoning accidents caused by misuse,suicide,or homicide have been reported in recent years.In China,fatal aconitine poisoning can occasionally happen on account of acci-dental ingestion of some wild plants or consumption of herbal decoction made from the roots of Aconitum plants.However,it is rather difficult for forensic experts to find the specific results in present forensic autopsy of aconitine-induced death.To further clarify its potential risk following the widespread application of aconitine,toxicological characteristics and pharmacokinetics of aconitine are reviewed.Moreover,gastrointestinal,neurological,and car-diovascular symptoms were observed frequently in aconitine poisoning cases.In addition,the review also aims at providing some convincing evidences for forensic experts to identify unexplained death with postmortem examination.Xiangting Gao Jun Hu Xincai Zhang Yuanyi Zuo Yun Wang Shaohua Zhu 2020Forensic Sciences Research2020,5,1:6
6Assessment of cognitive dysfunction in traumatic brain injury patients:a review显示文摘Traumatic brain injury(TBI)is one of the major causes of human mortality and morbidity in the world.Brain injury could affect the core of a person’s being–their thinking,memory,personality and behaviour.Electrophysiological markers from the human electroencephalogram and brain imaging provide a rich source of data which helps to elucidate specific processing impairments in TBI patients.To assess the cognitive and social function in traumatic brain injury patients,this review will focus on some of methods for assessing the disabling cognitive and social function deficits induced by TBI.There are many new technologies available to address TBI and recognition related questions.Integration of the various techniques will help to facilitate our comprehending of TBI,cognitive function and social function,and improve treatment and rehabilitation.Huiyan Sun Chengliang Luo Xiping Chen Luyang Tao 2017Forensic Sciences Research2017,2,4:5
7Vitality and wound-age estimation in forensic pathology:review and future prospects显示文摘Determining the age of a wound is challenging in forensic pathology,but it can contribute to the reconstruction of crime scenes and lead to arrest of suspects.Forensic scholars have tended to focus on evaluating wound vitality and determining the time elapsed since the wound was sustained.Recent progress in forensic techniques,particularly high-throughput analyses,has enabled evaluation of materials at the cellular and molecular levels,as well as simultaneous assessment of multiple markers.This paper provides an update on wound-age estimation in forensic pathology,summarizes the recent literature,and considers useful additional informa-tion provided by each marker.Finally,the future prospects for estimating wound age in foren-sic practise are discussed with the hope of providing something useful for further study.Na Li Qiuxiang Du Rufeng Bai Junhong Sun 2020Forensic Sciences Research2020,5,1:5
8Modern post-mortem imaging:an update on recent developments显示文摘Modern post-mortem investigations use an increasing number of digital imaging methods,which can be collected under the term“post-mortem imaging”.Most methods of forensic imaging are from the radiology field and are therefore techniques that show the interior of the body with technologies such as X-ray or magnetic resonance imaging.To digitally image the surface of the body,other techniques are regularly applied,e.g.three-dimensional(3D)surface scanning(3DSS)or photogrammetry.Today’s most frequently used techniques include post-mortem computed tomography(PMCT),post-mortem magnetic resonance imaging(PMMR),post-mortem computed tomographic angiography(PMCTA)and 3DSS or photogrammetry.Each of these methods has specific advantages and limitations.Therefore,the indications for using each method are different.While PMCT gives a rapid overview of the interior of the body and depicts the skeletal system and radiopaque foreign bodies,PMMR allows investigation of soft tissues and parenchymal organs.PMCTA is the method of choice for viewing the vascular system and detecting sources of bleeding.However,none of those radiological methods allow a detailed digital view of the body’s surface,which makes 3DSS the best choice for such a purpose.If 3D surface scanners are not available,photogrammetry is an alternative.This review article gives an overview of different imaging techniques and explains their applications,advantages and limitations.We hope it will improve understanding of the methods.Silke Grabherr Coraline Egger Raquel Vilarino Lorenzo Campana Melissa Jotterand Fabrice Dedouit 2017Forensic Sciences Research2017,2,2:5
9Forensic odontology identification response to terrorist attacks in Paris November 2015显示文摘The terrorist attacks of November 2015 led to the immediate death of 129 victims admitted to the Legal and Forensic Medicine Institute of Paris,including 41 unidentified.During the Disaster Victim Identification(DVI)operations,22 bodies were examined by the postmortem(PM)dental team with the aim of establishing PM odontograms.At the same time,the dental expert in the antemortem(AM)unit collected a large number of dental files,progressively filtered as the list of missing persons became reduced.Feedback from these events has highlighted the difficulties of implementing the DVI chain principles in a legal framework,published the day before the attacks,and also the technical complexity of collecting dental data on a week end of terror.The return on experience after this event has represented a paradigm shift on previous methods of DVI in Paris and even more in France.Indeed,the victim identification procedure was redesigned,integrating new technical means such as a CT scan directly on spot,allowing the extraction of maxillofacial data as soon as possible in order to support the PM dental examination team.Moreover,the National Dental Council proceeded to the overall remodeling of the dental identification unit,which is composed of trained members,from local,regional and national aspects.These forensic experts are dedicated,at the request of the legal authorities,to DVI operations and deployed throughout the country capable of managing AM and PM data.This unit aims also to share experiences and awarenessraising among health professionals and investigators in order to optimize a better submission of AM elements and also to enhance the major interest of odontology as a primary identifier in disaster.Steve Toupenay Aida Ben Cheikh Bertrand Ludes Rufino Felizardo 2020Forensic Sciences Research2020,5,3:4
10Forensic Automatic Speaker Recognition Based on Likelihood Ratio Using Acoustic-phonetic Features Measured Automatically显示文摘Forensic speaker recognition is experiencing a remarkable paradigm shift in terms of the evaluation framework and presentation of voice evidence.This paper proposes a new method of forensic automatic speaker recognition using the likelihood ratio framework to quantify the strength of voice evidence.The proposed method uses a reference database to calculate the within-and between-speaker variability.Some acoustic-phonetic features are extracted automatically using the software VbiceSauce.The effectiveness of the approach was tested using two Mandarin databases:A mobile telephone database and a landline database.The experimenfs results indicate that these acoustic-phonetic features do have some discriminating potential and are worth trying in discrimination.The automatic acoustic-phonetic features have acceptable discriminative performance and can provide more reliable results in evidence analysis when fused with other kind of voice features.Huapeng Wang Cuiling Zhang 2015Journal of Forensic Science and Medicine2015,1,2:4
11Pathology of atherosclerotic coronary artery disease in the young Indian population显示文摘Atherosclerotic coronary artery disease (CAD) is of great concern in young adults because of its potential to cause great incapacitation.This arena of cardiology has gained importance in South Asian countries,particularly India due to increased prevalence that is related to traditional risk factors,altered life styles and inherent risk factors.In this study,we sought to evaluate,at autopsy,the pathology of atherosclerotic CAD in young patients with ischemic heart disease (IHD).A 10-year retrospective autopsy-based study was carried out in a large tertiary-care centre and patients aged ≤45 years with IHD were selected.Out of 545 autopsied cases of IHD,95 patients (17.4%) were young.Among these 95 patients,84 (88.4%) had IHD related to atherosclerotic CAD;the youngest patient was 18years old.Predictably there was sole involvement of left anterior descending artery and the presence of fibrous plaques.Irrespective of the plaque morphology,the commonest complication was thrombosis produced by plaque erosion seen in 36.9% of patients.Acute coronary insufficiency was noted in 52 patients (61.9%),while healed infarctions were surprisingly noted in 28 patients (33.3%).Screening for IHD in the young population may help to improve prognosis by detecting subclinical disease,although more studies are necessary to establish reference limits for this young population.Additional research must also focus on treatment concerns that are specific to young patients.Pradeep Vaideeswar Shashank Tyagi Saranya Singaravel 2019Forensic Sciences Research2019,4,3:4
12The use of wastewater analysis in forensic intelligence:drug consumption comparison between Sydney and different European cities显示文摘Wastewater analysis offers objective and complementary information to illicit drug agencies by monitoring patterns of illicit drug consumption.In this study,wastewater samples from three different wastewater treatment plants in Sydney,Australia were collected in March 2016.Ten targeted drugs were analysed and temporal and geographical analyses were performed to obtain a better understanding of the type and amount of illicit drugs consumed in Sydney in comparison with similar studies conducted around Australia and in Europe.Among the targeted drugs,methamphetamine was consumed the most,followed by cocaine and 3,4-methylenedioxymethamphetamine(MDMA).Weekly patterns were observed where a peak during the weekend was present.The geographical analysis showed differences between the regions targeted.This observation may be related to socio-demographic aspects.The comparison of our study to other data sources from Australia showed a high consumption of methamphetamine in Sydney and Western Australia.The comparison between Sydney and different European cities revealed a difference in consumption,which is in line with traditional market indicators.The information obtained through wastewater analysis provides complementary information regarding illicit drug consumption,the size,and the evolution of the illicit drug market.This,ultimately,will assist authorities in making informed decisions.Anne Bannwarth Marie Morelato Lisa Benaglia Frederic Been Pierre Esseiva Olivier Delemont Claude Roux 2019Forensic Sciences Research2019,4,2:4
13Recent applications of isotope analysis to forensic anthropology显示文摘Isotope analysis has become an increasingly valuable tool in forensic anthropology case-work over the past decade. Modern-day isotopic investigations on human remains have integrated the use of multi-isotope profiles (e.g. C, N, O, H, S, Sr, and Pb) as well as iso-topic landscapes ('isoscapes') from multiple body tissues (e.g. teeth, bone, hair, and nails) to predict possible region-of-origin of unidentified human remains. Together, data from various isotope analyses provide additional lines of evidence for human identification, including a decedent's possible region-of-birth, long-term adult residence, recent travel history, and dietary choices. Here, we present the basic principles of isotope analysis and provide a brief overview of instrumentation, analytical standards, sample selection, and sample quality measures. Finally, we present case studies that reflect the diverse applications of isotope analysis to the medicolegal system before describing some future research directions. As shown herein, isotope analysis is a flexible and powerful geolocation tool that can provide new investigative leads for unidentified human remains cases.Eric J.Bartelink Lesley A.Chesson 2019Forensic Sciences Research2019,4,1:4
14Forensic odontology in DVI:current practice and recent advances显示文摘Forensic odontology frequently plays a significant role in identification of the victims of multi-fatality disasters,but not in all.It depends on adequate dental remains surviving the disaster and on the availability of dental records to be successful.This paper describes current practice in the techniques of identification in forensic odontology and outlines recent advances that are moving into the mainstream.Alex Forrest 2019Forensic Sciences Research2019,4,4:4
15Forensic investigation of 23 autosomal STRs and application in Han and Mongolia ethnic groups显示文摘A forensic validation study of the Early Access HuaxiaTM Platinum Polymerase Chain Reaction (PCR) kit was completed to document the performance capabilities and limitations.The genotyping of DNA samples was consistent across a large range of template DNA concentrations,with complete profiles obtained at 0.125 ng;however,no more than 2 mm× 1.2 mm punches of samples would be recommended for direct amplification.The size precision and accuracy test revealed the genotyping ability;while consistent results were obtained when comparing the kit with other commercially available systems.In addition,the whole PCR amplification can finish within approximately 45 min,making the system suitable for fastdetection.However,only partial profiles may be obtained with challenging samples,including DNA stored on Foam-Tipped Applicators (FTA) cards or some case samples.For the forensic application in ethnic groups,a total of 282 and 229 alleles were obtained in Han and Mongolia,respectively.Since the 23 short tandem repeats were independent from each other,the cumulative power of exclusion in duos was 0.999999157188 and the cumulative power of exclusion in trios was 0.999999999859 in the Han group while the cumulative power of exclusion in duos (CPEduo) was 0.999 998 848 26 and cumulative power of exclusion in trios (CPEtrio) was 0.999 999 999 79 in the Mongolia group.And good internal consistency was found between the two investigated groups and the Sichuan Han,Hui,Tibetan and Uygur according to available reference data.Xiang Sheng Yali Wang Jiashuo Zhang Liqin Chen Yuan Lin Zhenmin Zhao Chengtao Li Suhua Zhang 2018Forensic Sciences Research2018,3,2:4
16COVID-19 research:pandemic versus“paperdemic”,integrity,values and risks of the“speed science”显示文摘Scientific integrity is a learned skill.When researchers and students learn integrity in laboratories or in the classroom,they are empowered to use similar principles in other aspects of their lives.This commentary reviews the concepts related to scientific integrity at a time when science faces important challenges related to the increase number of articles produced regarding research on coronavirus disease 2019(COVID-19).Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has ignited another parallel viral pandemic,with science ranging from robust studies to dishonest studies being conducted,posted,and shared at an unprecedented rate.A balance is needed between the benefits of the rapid access to new scientific data and the threat of causing panic or erroneous clinical decisions based on mistakes or misconduct.The truth is that the“scientific research has changed the world”but now,and more than ever,“it needs to change itself”.A pandemic with a“paperdemic”will be even more complicated to manage if it progresses in an uncontrolled manner and is not properly scrutinized.Ricardo Jorge Dinis-Oliveira 2020Forensic Sciences Research2020,5,2:4
17State of the art in post-mortem forensic imaging in China显示文摘The autopsy and histopathologic examination are traditional and classic approaches in forensic pathology.In recent years,with the tremendous progresses of computer technology and medical imaging technology,the developed post-mortem computer tomography,post-mortem magnetic resonance imaging and other new methods provide non-invasive,intuitive,high-precision examining methods and research tools for the forensic pathology.As a result,the reconstruction of the injury as well as the analysis of injury mechanism has been essentially achieved.Such methods have become popular in the research field of forensic science and related work has also been carried out in China.This paper reviews the development and application of abovementioned post-mortem forensic imaging methods in China based on the relevant literature.Yijiu Chen 2017Forensic Sciences Research2017,2,2:4
18A brief review of forensically important flesh flies (Diptera: Sarcophagidae)显示文摘Forensic entomology could provide valuable data for the minimum postmortem interval (PMImin) estimation and other relevant information,such as causes and circumstances of death.Some representatives of flesh flies are one of the dominant necrophagous insects during early stages of decomposition,demonstrating unique biological characteristics compared with other necrophagous flies.Moreover,they lead to global health concerns as carriers of various pathogenic micro-organisms,and dominantly result in the traumatic myiasis.Thus,sarcophagid flies are considered important in decomposition processes for PMImin estimation.However,the utility of sarcophagid flies has been seriously hampered by limited ecological,biological and taxonomic knowledge of them.The aim of this paper is to provide a brief review on the species,distribution and biological habit of forensically important sarcophagid flies.In addition,the relation between traumatic myiasis and flesh flies,molecular identification methods and developmental pattern of flesh flies are summarized.Lipin Ren Yanjie Shang Wei Chen Fanming Meng Jifeng Cai Guanghui Zhu Lushi Chen Yong Wang Jianqiang Deng Yadong Guo 2018Forensic Sciences Research2018,3,1:3
19Validation of the DNATyper^(TM)15 PCR Genotyping System for Forensic Application显示文摘We describe the optimization and validation of the DNATyper^(TM)15 multiplex polymerase chain reaction(PCR)genotyping system for autosomal short tandem repeat(STR)amplification at 14 autosomal loci(D6S1043,D21S11,D7S820,CSF1PO,D2S1338,D3S1358,D13S317,D8S1179,D16S539,Penta E,D5S818,vWA,D18S51,and FGA)and amelogenin,a sex‑determining locus.Several DNATyper^(TM)15 assay variables were optimized,including hot start Taq polymerase concentration,Taq polymerase activation time,magnesium concentration,primer concentration,annealing temperature,reaction volume,and cycle number.The performance of the assay was validated with respect to species specificity,sensitivity to template concentration,stability,accuracy,influence of the DNA extraction methods,and the ability to genotype the mixture samples.The performance of the DNATyper^(TM)15 system on casework samples was compared with that of two widely used STR amplification kits,Identifiler^(TM)(Applied Biosystems,Carlsbad,CA,USA)and PowerPlex 16®(Promega,Madison,WI,USA).The conditions for PCR‑based DNATyper^(TM)15 genotyping were optimized.Contamination from forensically relevant nonhuman DNA was not found to impact genotyping results,and full profiles were generated for all the reactions containing≥0.125 ng of DNA template.No significant difference in performance was observed even after the DNATyper^(TM)15 assay components were subjected to 20 freeze‑thaw cycles.The performances of DNATyper^(TM)15,Identifiler^(TM),and PowerPlex 16®were comparable in terms of sensitivity and the ability to genotype the mixed samples and case‑type samples,with the assays giving the same genotyping results for all the shared loci.The DNA extraction methods did not affect the performance of any of the systems.Our results demonstrate that the DNATyper^(TM)15 system is suitable for genotyping in both forensic DNA database work and case‑type samples.Jian Ye Chengtao Jiang Xingchun Zhao Le Wang Caixia Li Anquan Ji Li Yuan Jing Sun Shuaifeng Chen 2015Journal of Forensic Science and Medicine2015,1,1:3
20Study on Accuracy of Judgments by Chinese Fingerprint Examiners显示文摘The interpretation of fingerprint evidence depends on the judgments of fingerprint examiners.This study assessed the accuracy of different judgments made by fingerprint examiners following the Analysis,Comparison,and Evaluation(ACE)process.Each examiner was given five marks for analysis,comparison,and evaluation.We compared the experts’judgments against the ground truth and used an annotation platform to evaluate how Chinese fingerprint examiners document their comparisons during the identification process.The results showed that different examiners demonstrated different accuracy of judgments and different mechanisms to reach them.Shiquan Liu Christophe Champod Jian Wu Yaping Luo 2015Journal of Forensic Science and Medicine2015,1,1:3
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