Mechanical Stress Induces Neuroendocrine and Immune Responses of Sea Cucumber(Apostichopus japonicus)

查看全文 作　　者：TAN [1,1]Jie;LI [2]Fenghui;SUN [3]Huiling;GAO [3]Fei;YAN [3]Jingping;Gai [4]Chunlei;Chen [5]Aihua;WANG [3]Qingyin

机构地区：[1]College of Marine Life Sciences, Ocean University of China;[2]College of Fisheries and Life Science, Shanghai Ocean University;[3]Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences;[4]Key Laboratory of Mariculture Disease Treatment, Provincial Mariculture Institute of Shandong;[5]Municipal Oceanic and Fishery Administration of Rushan

出　　处：《Journal of Ocean University of China》索引2015年第14卷第2期,共7页

基　　金：financially supported by the 863 High Technology Project of the Ministry of Science and Technology (No. 2012AA10A412-4);the Special Funds for the Basic B & D Program in the Central Non-profit Research Institutes (No. 2010-cb-03);Science and Technology Development Planning Project of Shandong Province (No. 2012GGA06021);Science and Technology Development Fund of Shinan district of Qingdao (No. 2011-5-023-QT) 摘　　要：Grading procedure in routine sea cucumber hatchery production is thought to affect juvenile sea cucumber immunological response. The present study investigated the impact of a 3-min mechanical perturbation mimicking the grading procedure on neuroendocrine and immune parameters of the sea cucumber Apostichopus japonicus. During the application of stress, concentrations of noradrenaline and dopamine in coelomic fluid increased significantly, indicating that the mechanical perturbation resulted in a transient state of stress in sea cucumbers. Coelomocytes concentration in coelomic fluid increased transiently after the beginning of stressing, and reached the maximum in 1 h. Whereas, coelomocytes phagocytosis at 3 min, superoxide anion production from 3 min to 0.5 h, acid phosphatase activity at 0.5 h, and phenoloxidase activity from 3 min to 0.5 h were all significantly down-regulated. All of the immune parameters recovered to baseline levels after the experiment was conducted for 8 h, and an immunostimulation occurred after the stress considering the phagocytosis and acid phosphatase activity. The results suggested that, as in other marine invertebrates, neuroendocrine/immune connections exist in sea cucumber A. japonicus. Mechanical stress can elicit a profound influence on sea cucumber neuroendocrine system. Neuroendocrine messengers act in turn to modulate the immunity functions. Therefore, these effects should be considered for developing better husbandry procedures. 关键词：神经内分泌系统机械应力应力诱导免疫反应海参酸性磷酸酶活性海洋无脊椎动物去甲肾上腺素

相关文献

参考文献（44）
引证文献（0）
耦合文献（5）

参考文献(44)

耦合文献(5)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Mechanical Stress Induces Neuroendocrine and Immune Responses of Sea Cucumber(Apostichopus japonicus)

参考文献(44)

耦合文献(5)

用户提示