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| 1 | 磷酸镁基骨水泥强度的影响因素及改性策略显示文摘磷酸镁基骨水泥(magnesium phosphate cements,MPCs)是一类新型无机骨修复材料,主要由氧化镁和磷酸盐通过水化反应而成;因其具备良好的生物学和物理学特性近年来引起研究者的极大兴趣。但现有MPCs的机械强度仍远低于人体骨,这极大地限制了其临床应用。探索具有合适机械强度的MPCs应用于临床是当前研究的急重热点。本文就目前关于MPCs机械强度方面的研究及改性进行综述。 | 邱永龙 郭卫春 李威 | 2022 | 医学研究杂志2022，51，2： | 0 |
| 2 | The Comparative Study of Gelatin/CNT-contained Mg-Ca-P Bone Cement with the Plain and CNT-reinforced Ones显示文摘Mimicking compositional and constructional features of the extracellular matrix(ECM)is an effective parameter in improving the biological response of biomaterials.In this regard,carbon nanotube(CNT)and gelatin were added to magnesium-calcium phosphate cement(CNG)to mimic fibrillar construction and organic composition of ECM,respectively,besides the CNG performance was compared with the plain and CNT-reinforced cement.Cementation behavior of the cements was investigated by evaluating their setting time,cement composition variation during setting,and viscosity fluctuation.Furthermore,compressive strength,degradation,and cell response of the cements were compared.Adding 5 wt.%gelatin reduced setting time about 60%,because of gel formation,not due to struvite precipitation.Moreover,the gelatin decreased compressive strength by about 20%.Although gelatin decreased compressive strength,the strength remained in the range attributed to trabecular bone.All the types of cement indicated shear thinning behavior that made their injectability feasible.Compared to other types of cement,CNG enhanced proliferation and differentiation of mesenchymal stem cells besides faster degradation,nontoxicity and suitable cell adhesion.Hence,mimicking features of CNG enhanced osteoconductivity and osteoinductivity of the cement compared to the plain one. | Mohammad Hossein Esnaashary Masoud Karfarma Hamid Reza Rezaie Alireza Khavandi Jafar Javadpour | 2021 | Journal of Bionic Engineering2021，18，3： | 0 |
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