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| 1 | 影响上消化道出血的相关危险因素显示文摘上消化道出血为内科常见急危重症之一,其因较高的发病率和病死率而在全球范围内受到广泛关注。本文对上消化道出血的相关危险因素进行总结,发现年龄、性别、幽门螺杆菌感染、慢性肾功能不全、心功能不全应用左室辅助装置、长期单独或联合应用非甾体类抗炎药(non-steroid anti-inflammatory drugs,NSAIDs)、选择性5-羟色胺再摄取抑制剂(selective serotonin reuptake inhibitors,SSRIs)等药物、气象因素和吸烟饮酒等不良生活习惯为发病的危险因素。VKORC基因多态性等其他可能的危险因素还需进一步研究。明确上消化道出血的危险因素,可优化相关高危人群的管理及治疗策略,有效预防上消化道出血的发生,对提高患者生活质量、节约卫生经费具有重要意义。 | 袁玥(综述) 郝建宇 刘心娟(审校) | 2021 | 临床与病理杂志2021,41,7: | 11 |
| 2 | 胃肠道毛细血管扩张症显示文摘胃肠道毛细血管扩张症为最常见的胃肠道良性血管发育异常病变,通常是血管本身的异常,也可以是某一系统性病症或某一综合征的表现之一。本病大多数患者无消化道症状,仅于内镜检查时偶然发现,部分患者表现为隐匿性消化道出血,极少数患者发生急性胃肠道出血。目前该病的治疗方法有对症支持治疗、内镜下治疗、药物治疗、血管栓塞治疗、手术治疗等。本文就胃肠道毛细血管扩张症的临床特征及治疗方法作一概述。 | 刘文倩 唐庆林 张鸣青 邓立新 温春虹 赖际霞 | 2021 | 胃肠病学和肝病学杂志2021,30,12: | 4 |
| 3 | 海德综合征诊治研究新进展显示文摘1958年,Heyde医生首次报道主动脉瓣狭窄(aortic valve stenosis,AS)合并不明原因消化道出血(gastrointestinal bleeding,GIB)的系列病例引起了医学界的广泛关注和讨论。经过数十年的探索,1992年Warkentin等[1]提出了血管性血友病因子(von Willebrand factor,vWF)高分子量多聚体(high-molecular-weight multimers of vWF,HMWM-vWFs)缺乏所致的获得性血管性血友病综合征(acquired von Willebrand syndrome,AVWS)可能是AS合并出血性胃肠道血管发育不良(angiodysplasia,AD)的重要机制,同年该症候群被命名为海德综合征(Heyde’s syndrome,HS)。 | 李睿 章洁淳 李志鹏 卿立金 吴伟 | 2022 | 中国心血管杂志2022,27,1: | 0 |
| 4 | Comparison of the performance of MS enteroscope series and Japanese double-and single-balloon enteroscopes显示文摘BACKGROUND Small intestine disease endangers human health and is not easy to locate and diagnose.AIM To observe the effect of the MS series of small intestine endoscopes on the gastrointestinal tract,the changes in serum gastrin levels and intestinal tissue,and the time required for the examination.METHODS In vivo experiments in 20 Living pigs were conducted,Bowel preparation was routinely performed,Intravenous anesthesia with propofol and ketamine was applied,the condition of the small intestine was observed and the detection time of the MS series of small intestine endoscopes were recorded,The changes in intestinal tissue using the MS series of small intestine endoscopes observed and compared before and after the examination,Venous blood(3-5 mL)from pigs was collected before and after the experiment;changes in intestinal tissue after use of the MS series of small intestine endoscopes observed after examination.After completion of each type of small intestine endoscope experiment,the pigs were allowed to rest and the next type of small intestine endoscope experiment was performed after 15 days of normal feeding.The detection time data of the single-balloon small intestine endoscope and doubleballoon small intestine endoscope were collected from four hospitals.RESULTS One case of Ascarislumbricoides,one of suspected Crohn’s disease,one small intestinal diverticulum and one anesthesia accident were observed in pigs.The small intestine showed no differences in the MS series of small intestine endoscopes and there were no differences in serum gastrin between the groups(P>0.05).The time required for inspection was recorded,and the overall detection time for the Japanese small intestine endoscopes was approximately 1.68±0.16 h.CONCLUSION Intestinal ascariasis is a common disease in pigs.Some pigs have abnormal intestinal variation.After continuous upgrade and improvement,the MS-3 and MS-4 small intestine endoscope appear superior in terms of detection time. | Jin-Hua Liu Dan-Yang Liu Yong-Feng Yuan Xue-Jun Sun Shu-Mei Shan | 2022 | World Journal of Gastroenterology2022,28,13: | 0 |
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