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| 1 | Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications显示文摘Major depressive disorder(MDD),also referred to as depression,is one of the most common psychiatric disorders with a high economic burden.The etiology of depression is still not clear,but it is generally believed that MDD is a multifactorial disease caused by the interaction of social,psychological,and biological aspects.Therefore,there is no exact pathological theory that can independently explain its pathogenesis,involving genetics,neurobiology,and neuroimaging.At present,there are many treatment measures for patients with depression,including drug therapy,psychotherapy,and neuromodulation technology.In recent years,great progress has been made in the development of new antidepressants,some of which have been applied in the clinic.This article mainly reviews the research progress,pathogenesis,and treatment of MDD. | Zezhi Li Meihua Ruan Jun Chen Yiru Fang | 2021 | Neuroscience Bulletin2021，37，6： | 13 |
| 2 | 新型抗焦虑药物研究进展显示文摘焦虑障碍是我国成人患病率最高的精神疾病,但其治疗药物的研发却一直滞后于该疾病的医疗需求。目前临床常用的抗焦虑药物主要包括部分苯二氮[艹卓]类药物、非苯二氮[艹卓]类药物和部分抗抑郁药,大多具有令人不快的副作用。该文通过检索Pubmed的文献资料,从内源性大麻素系统、肠-微生物-脑轴和GABA A受体亚基3个角度切入,总结介绍近年新型抗焦虑药物的研究进展,希望能够为该领域的发展提供帮助。 | 郑天歌 张青杰 贾靖仪 梁建辉 | 2021 | 中国药理学通报2021，37，9： | 9 |
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