共被期刊论文引用了2次
您的检索式：您选中1篇文献正在查看引证文献汇总
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 阿维A结合CO_(2)激光术治疗多发性尖锐湿疣的临床疗效及安全性显示文摘目的观察阿维A结合CO_(2)激光术治疗多发性尖锐湿疣的临床疗效及安全性。方法选取2020年1月—2022年1月龙岩人民医院收治的多发性尖锐湿疣患者80例,根据随机数字法分为激光组和联合组,各40例。激光组患者采用CO_(2)激光术治疗,联合组患者在激光组基础上予以阿维A胶囊治疗3个月。比较2组临床疗效,治疗前及治疗3个月后汉密尔顿抑郁量表(HAMD)评分、汉密尔顿焦虑量表(HAMA)评分,3个月内疾病复发率及不良反应发生率。结果联合组总有效率高于激光组(95.00%vs.70.00%,χ^(2)=8.658,P=0.003)。治疗3个月后,2组HAMD评分、HAMA评分均低于治疗前,且联合组HAMD评分、HAMA评分低于激光组(P<0.01)。联合组3个月内疾病复发率为5.00%,低于激光组的22.50%(χ^(2)=5.165,P=0.023)。联合组与激光组不良反应总发生率比较,差异无统计学意义(7.50%vs.0,χ^(2)=3.117,P=0.077)。结论采用阿维A结合CO_(2)激光术治疗多发性尖锐湿疣患者可增强疗效,降低疾病复发率,缓解患者焦虑、抑郁情绪,且具有一定安全性。 | 朱雪桦 | 2023 | 临床合理用药杂志2023，16，24： | 0 |
| 2 | Anal human papilloma viral infection and squamous cell carcinoma:Need objective biomarkers for risk assessment and surveillance guidelines显示文摘High grade anal intraepithelial neoplasia due to human papilloma viral(HPV)infections is a precursor lesion for squamous cell carcinoma especially in high risk populations.Frequent examination and anal biopsies remain unpopular with patients;moreover they are also risk factors for chronic pain,scarring and sphincter injury.There is lack of uniform,surveillance methods and guidelines for anal HPV specifically the intervals between exam and biopsies.The aim of this editorial is to discuss the intervals for surveillance exam and biopsy,based on specific HPV related biomarkers?Currently there are no published randomized controlled trials documenting the effectiveness of anal screening and surveillance programs to reduce the incidence,morbidity and mortality of anal cancers.In contrast,the currently approved screening and surveillance methods available for HPV related cervical cancer includes cytology,HPV DNA test,P16 or combined P16/Ki-67 index and HPV E/6 and E/7 mRNA test.There are very few studies performed to determine the efficacy of these tests in HPV related anal precancerous lesions.The relevance of these biomarkers is discussed in this editorial.Longitudinal prospective research is needed to confirm the effectiveness of these molecular biomarkers that include high risk HPV serotyping,P16 immuno-histiochemistry and E6/E7 mRNA profiling on biopsies to elucidate and establish surveillance guidelines. | Santosh Shenoy | 2022 | World Journal of Gastrointestinal Oncology2022，14，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员