|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | In vitro corrosion resistance of a Ta2O5 nanofilm on MAO coated magnesium alloy AZ31 by atomic layer deposition显示文摘Micro-arc oxidation(MAO)coating with outstanding adhesion strength to Mg alloys has attracted more and more attention.However,owing to the porous structure,aggressive ions easily invaded the MAO/substrate interface through the through pores,limiting long-term corrosion resistance.Therefore,a dense and biocompatible tantalum oxide(Ta2O5)nanofilm was deposited on MAO coated Mg alloy AZ31 through atomic layer deposition(ALD)technique to seal the micropores and regulate the degradation rate.Surface micrography,chemical compositions and crystallographic structure were characterized using FE-SEM,EDS,XPS and XRD.The corrosion resistance of all samples was evaluated through electrochemical and hydrogen evolution tests.Results revealed that the Ta2O5 film mainly existed in the form of amorphousness.Moreover,uniform deposition of Ta2O5 film and effective sealing of micropores and microcracks in MAO coating were achieved.The current density(icorr)of the composite coating decreased three orders of magnitude than that of the substrate and MAO coating,improving corrosion resistance.Besides,the formation and corrosion resistance mechanisms of the composite coating were proposed. | Chang-Yang Li Chi Yu Rong-Chang Zeng Bo-Cheng Zhang Lan-Yue Cui Jun Wan Yang Xia | 2020 | Bioactive Materials2020，5，1： | 11 |
| 2 | Investigation of Mg–Zn–Y–Nd alloy for potential application of biodegradable esophageal stent material显示文摘In recent years,due to unhealthy dietary habits and other reasons,advanced esophageal cancer patients are on the rise,threatening human health and life safety at all times.Stents implantation as an important complementary or alternative method for chemotherapy has been widely applied in clinics.However,the adhesion and proliferation of pathological cells,such as tumor cells,fibroblasts and epithelial cells,may interfere the efficacy of stents.Further multiple implantation due to restenosis may also bring pain to patients.In this contribution,we preferred a biodegradable material Mg–Zn–Y–Nd alloy for potential application of esophageal stent.The hardness testing showed that Mg–Zn–Y–Nd alloy owned less mechanical properties compared with the commercial esophageal stents material,317L stainless steel(317L SS),while Mg–Zn–Y–Nd displayed significantly better biodegradation than 317L SS.Cell apoptosis assay indicated Mg–Zn–Y–Nd inhibited adhesion and proliferation of tumor cells,fibroblasts and epithelial cells.Our research suggested potential application of Mg–Zn–Y–Nd alloy as a novel material for biodegradable esophageal stent. | Shuo Wang Xueqi Zhang Jingan Li Changsheng Liu Shaokang Guan | 2020 | Bioactive Materials2020，5，1： | 7 |
| 3 | In vitro degradation of pure magnesium-the synergetic influences of glucose and albumin显示文摘The biocorrosion of magnesium in the external physiological environment is still difficult to accurately evaluate the degradation behavior in vivo,particularly,in the microenvironment of the patients with hyperglycemia or diabetes.Thus,we explored the synergistic effects of glucose and protein on the biodegradation of pure magnesium,so as to have a deeper understanding the mechanism of the degradation in vivo.The surface morphology and corrosion product composition of pure magnesium were investigated using SEM,EDS,FTIR,XRD and XPS.The effect of glucose and albumin on the degradation rate of pure magnesium was investigated via electrochemical and immersion tests.The adsorption of glucose and albumin on the sample surface was observed using fluorescence microscopy.The results showed that the presence of 2 g/L glucose changed the micromorphology of corrosion products on the magnesium surface by reacting with metal cations,thus inhibiting the corrosion of pure magnesium.Protein formed a barrier layer to protect the magnesium at early stage of immersion.The chelation reaction between protein and magnesium surface might accelerate the degradation at later stage.There may be a critical glucose(albumin)content.Biodegradation of pure magnesium was inhibited at low concentrations and promoted at high concentrations.The synergistic effect of glucose and protein restrained the adsorption of aggressive chloride ions to a certain extent,and thus inhibited the degradation of pure magnesium considerably.Moreover,XPS results indicated that glucose promoted the adsorption of protein on the sample surface. | Wei Yan Yi-Jie Lian Zhi-Yuan Zhang Mei-Qi Zeng Zhao-Qi Zhang Zheng-Zheng Yin Lan-Yue Cui Rong-Chang Zeng | 2020 | Bioactive Materials2020，5，2： | 6 |
| 4 | 仿生矿化细胞保护壳的制备及其在环境微生物领域的研究进展显示文摘自然界中部分生物体能够产生矿物质形成矿化保护壳,保护壳在提高生物体对外界不利环境的抗性和改善生命功能方面展现出良好的效果。为了利用保护壳的诸多优势,科研人员深入研究生物矿化机理,开发出多种仿生矿化方法,为不能自然产生矿化壳的生物体制备人工保护壳,具有保护壳的生物体在疾病治疗、环境保护和新能源等领域展现出广阔的应用前景。主要围绕微生物细胞保护壳的制备方法和功能价值进行讨论。首先从制备机理、制备过程和适用范围方面介绍细胞保护壳的主要制备方法,然后阐明矿化壳在保护细胞免受外界侵害和室温储存细胞方面的应用价值,最后对具有保护壳的微生物在环境污染治理方面的应用进行展望。 | 贾方旭 蔡琳娜 范利茹 蔡伟伟 李泓洋 邢薇 姚宏 | 2021 | 环境工程2021，39，5： | 1 |
| 5 | Regulation of osteoblast functions on titanium surfaces with different micro/nanotopographies and compositions显示文摘Surface modification of medical implants is considered as an effective method to improve cellular behaviors and the integration of tissues with materials. Titanium(Ti)-based materials with four different micro/nano-structures and compositions were prepared by acid etching, electrochemical anodization and alkali-heat treatment. The surface morphologies and compositions of the different surface-modified Ti materials were characterized by field-emission scanning electron microscopy(FE-SEM),atomic force microscopy(AFM) and X-ray diffraction(XRD). The effects of the micro/nano structured and compositions of the surfaces on cellular responses were investigated in vitro by observing the morphology, adhesion, proliferation and osteogenic differentiation of osteoblasts. To further investigate the underlying mechanisms, an RT-PCR assay was performed to analyze the expression levels of cell adhesion-related genes. Our results indicated that the nanosized structure and anatase composition could promote the adhesion and proliferation of MC3T3-E1 pre-osteoblast, as well as alkaline phosphatase activity and extracellular matrix mineralization via the integrin-FAK signaling pathway. Taken together, our innovation presented in this work demonstrated that the surface nano-structure design and composition of biomedical implants can be modified of for future orthopaedic applications. | HE Peng WANG XiaoLan NING ChengYun LIU XiaoWei LI Mei XU HaiDong GUO GuoDong MAO GuangPing LIU Gang XU Bin ZHANG Yu ZHAO JianNing | 2019 | Science China(Technological Sciences)2019，62，4： | 0 |
| 6 | 水热温度和时间对3D打印Ti-6Al-4V植入体表面理化性能的影响显示文摘目的 研究在具有微纳米双级结构的3D打印钛合金植入体表面制备聚多巴胺涂层的最佳工艺及参数。方法 对酸蚀和阳极氧化处理后的3D打印Ti-6Al-4V样品进行水热处理,通过水热法将聚多巴胺添加到样品表面,并分析不同水热温度和时间的处理效果。使用扫描电子显微镜、三维共聚焦激光显微镜、X射线光电子能谱仪、接触角测量仪、电化学工作站对各组样品的表面形貌、粗糙度、元素组成、表面润湿性、耐腐蚀性等进行表征。结果 经过酸蚀和阳极氧化处理后,在3D打印钛合金植入体表面成功制备了微纳米双级结构,表面纳米管的管径为80nm左右,水热处理后各组表面均可以观察到有涂层附着。样品表面元素分析结果表明,各组样品表面的N/C值均与理论值0.125接近,证明水热处理成功在微纳米结构表面添加了聚多巴胺涂层。随着水热处理温度的升高和时间的延长,纳米管的管径逐渐减小,由80nm减小至40nm左右。随着反应时间的延长,样品表面粗糙度逐渐降低,各组粗糙度均保持在4~5μm,且接触角逐渐减小,酸蚀后的表面接触角为52.1°,阳极氧化后,接触角降低至42.9°。经过水热处理,各组接触角均小于35°,表现出较好的亲水性。相比于酸蚀组和阳极氧化组,水热处理后的各组的耐腐蚀性均得到增强。结论 在基本保留原有微纳米双级结构的前提下,37℃的反应温度和24 h的反应时间适用于聚多巴胺在钛合金植入体表面的沉积。研究结果为聚多巴胺在钛合金植入体表面自聚合的工艺参数优化提供了参考。 | 纪振冰 万熠 赵梓贺 于明志 王宏卫 范世缘 | 2022 | 表面技术2022，51，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员