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| 1 | Taurine Transporter dEAAT2 is Required for Auditory Transduction in Drosophila显示文摘Drosophila dEAAT2, a member of the excitatory amino-acid transporter(EAAT) family, has been described as mediating the high-affinity transport of taurine, which is a free amino-acid abundant in both insects and mammals. However, the role of taurine and its transporter in hearing is not clear. Here, we report that dEAAT2 is required for the larval startle response to sound stimuli. d EAAT2 was found to be enriched in the distal region of chordotonal neurons where sound transduction occurs. The Ca^(2+) imaging and electrophysiological results showed that disrupted dEAAT2 expression significantly reduced the response of chordotonal neurons to sound.More importantly, expressing d EAAT2 in the chordotonal neurons rescued these mutant phenotypes. Taken together,these findings indicate a critical role for Drosophila dEAAT2 in sound transduction by chordotonal neurons. | Ying Sun Yanyan Jia Yifeng Guo Fangyi Chen Zhiqiang Yan | 2018 | Neuroscience Bulletin2018，34，6： | 4 |
| 2 | Molecular Basis for Cephalic Mechanosensitivity of Drosophila Larvae显示文摘Dear Editor,For an animal to explore its environment,the mechanosensors on its head are of particular importance.For example,in Drosophila larvae that constantly explore the surrounding substrate during foraging and wandering,the cephalic segments host highly specialized organs with extraordinary mechanical sensitivity [1]. | Zhenyu Zhang Zhiyuan Li Ting Liu Wei Zhang | 2020 | Neuroscience Bulletin2020，36，9： | 0 |
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