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| 1 | Ex-press青光眼引流钉植入术治疗不同类型青光眼的长期临床观察显示文摘目的评价Ex-press青光眼引流钉植入术治疗不同类型青光眼的有效性和安全性。方法回顾分析于我院行P50型Ex-press青光眼引流钉植入术的不同类型青光眼患者209例(283眼),包括原发性开角型青光眼(POAG)组135眼、原发性闭角型青光眼(PACG)组12眼、发育性青光眼(DG)组94眼、继发性青光眼(SG)组42眼,比较了手术成功率,术后眼压、视力,抗青光眼药物使用数量及并发症。结果术后平均随访(26.7±10.7)个月。术后36个月,POAG组的完全成功率(68.8%)明显高于PACG组(40.0%)和SG组(47.6%),DG组的完全成功率(65.1%)明显高于SG组(47.6%),以上P值均<0.05。各组青光眼术后眼压较术前均明显下降(P<0.05),术后不同随访时间各组间平均眼压差异无统计学意义(P>0.05)。各组视力均在术后1周明显下降(P<0.05),术后1个月恢复至术前水平。SG组术后抗青光眼药物使用数量(1.05±1.13)明显高于POAG组(0.51±1.22)、PACG组(0.83±0.84)及DG组(0.63±0.90),P值均<0.05。SG组术后并发症总发生率(40.48%)高于POAG组(15.56%)和DG组(21.28%),P值均<0.05。结论Ex-press青光眼引流钉植入术治疗POAG和DG有较好的有效性和安全性,对于PACG和SG的治疗则需根据临床情况谨慎选择。 | 郑蓥蓥 张玉秋 王晓蕾 孙兴怀 | 2020 | 中国眼耳鼻喉科杂志2020，20，4： | 4 |
| 2 | Ex-PRESS implantation for different types of glaucoma显示文摘AIM: To evaluate the clinical results, efficacy and safety of Ex-PRESS P200 glaucoma shunt implant in different types of medically uncontrolled glaucoma. METHODS: The study included 31 eyes of 31 patients that were unresponsive to medical antiglaucomatous therapy in whom Ex-PRESS P200 glaucoma shunt implantation was performed. The demographic characteristics of the patients, type of glaucoma, complete ocular examination results, number of antiglaucomatous drugs before and after surgery, early and late complications of surgery, additional surgical and nonsurgical medical interventions, and success rates were investigated from the patients’ files, retrospectively. RESULTS: The mean postoperative follow-up time was 16.4±7.5 mo. The preoperative mean corrected intraocular pressure(IOP) was 28.7±10.3 mm Hg and postoperative mean corrected IOP was 15.3±5.2 mm Hg(P<0.05) at the last visit. The mean IOP reduction was 39.9% when the preoperative and postoperative values of the last visits were compared. The average number of antiglaucomatous drug use decreased from 3.9±0.3 to 1.7±1.7 postoperatively(P<0.05). The use of antiglaucomatous medications at the last visit was more than in other studies in the literature. The most common complication was conjunctival leakage, which was seen in 7 patients. Other early complications were iris touch, intravitreal hemorrhage, hyphema, choroidal effusion, early transient hypotonia and corneal edema. One of the late complications was endophthalmitiswhich was seen in one case 6 mo after the operation, and the other late complication was opacification of the cornea in one patient. Twelve additional surgical operations associated to Ex-PRESS surgery and 3 bleb needling have done. At the last visit, the complete success rate was 32.3% and the qualified success rate was 77.5% in all patients. CONCLUSION: Ex-PRESS P200 glaucoma shunt implantation may be an effective procedure for medically uncontrolled glaucoma with significantly lower use of antiglaucomatous medications. | Meltem Guzin Altinel Ayse Yagmur Kanra Remzi Karadag Huseyin Bayramlar | 2019 | International Journal of Ophthalmology(English edition)2019，12，8： | 3 |
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